Schoenheimer effect explained - Feedback regulation of cholesterol synthesis in mice mediated by Insig proteins

Journal of Clinical Investigation

Volumn 115, Issue 9, 2005, Pages 2489-2498

  Engelking, Luke J ^a   Liang, Guosheng ^a   Hammer, Robert E ^a   Takaishi, Kiyosumi ^a   Kuriyama, Hiroshi ^a   Evers, Bret M ^a   Li, Wei Ping ^b   Horton, Jay D ^a   Goldstein, Joseph L ^a   Brown, Michael S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE CITRATE LYASE; CHOLESTEROL; FATTY ACID; FATTY ACID SYNTHASE; GENOMIC DNA; GLUCOSE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; INSULIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN RECEPTOR; RNA; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; DIETARY INTAKE; EMBRYO; ENZYME ACTIVITY; FAT INTAKE; FATTY ACID BLOOD LEVEL; FATTY ACID SYNTHESIS; FEEDBACK SYSTEM; GENOTYPE; GLUCOSE BLOOD LEVEL; IMMUNOBLOTTING; INSULIN BLOOD LEVEL; LIVER WEIGHT; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL;

ALLELES; ANIMALS; BRAIN; CHOLESTEROL; CHOLESTEROL, DIETARY; FEEDBACK, BIOCHEMICAL; FEMALE; GENE TARGETING; LIPIDS; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEINS; TRIGLYCERIDES;

EID: 24644463295     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI25614     Document Type: Article

References (50)

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