-
1
-
-
0002230202
-
Familial hypercholesterolemia
-
C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill Publishing Co., New York
-
Goldstein, J.L., and M.S. Brown. 1989. Familial hypercholesterolemia. In The Metabolic Basis of Inherited Disease. C.R. Scriver, A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill Publishing Co., New York. 1215-1250.
-
(1989)
The Metabolic Basis of Inherited Disease
, pp. 1215-1250
-
-
Goldstein, J.L.1
Brown, M.S.2
-
2
-
-
0025095799
-
Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects
-
Rubinsztein, D.C., J.C. Cohen, G.M. Berger, D.R. van der Westhuyzen, G.A. Coetzee, and W. Gevers. 1990. Chylomicron remnant clearance from the plasma is normal in familial hypercholesterolemic homozygotes with defined receptor defects. J. Clin. Invest. 86:1306-1312.
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 1306-1312
-
-
Rubinsztein, D.C.1
Cohen, J.C.2
Berger, G.M.3
Van Der Westhuyzen, D.R.4
Coetzee, G.A.5
Gevers, W.6
-
3
-
-
0027258140
-
Hypercholesterolemia in LDL receptor knockout mice and its reversal by adenovirus-mediated gene delivery
-
Ishibashi, S., M.S. Brown, J.L. Goldstein, R.D. Gerard, R.E. Hammer, and J. Herz. 1993. Hypercholesterolemia in LDL receptor knockout mice and its reversal by adenovirus-mediated gene delivery.J. Clin. Invest. 92:883-893.
-
(1993)
J. Clin. Invest.
, vol.92
, pp. 883-893
-
-
Ishibashi, S.1
Brown, M.S.2
Goldstein, J.L.3
Gerard, R.D.4
Hammer, R.E.5
Herz, J.6
-
4
-
-
0348038758
-
Hepatic uptake of chylomicron remnants in WHHL rabbits: A mechanism genetically distinci from the low density lipoprotein receptor
-
Kita, T., J.L. Goldstein, M.S. Brown, Y. Watanabe, C.A. Hornick, and R.J. Havel. 1982. Hepatic uptake of chylomicron remnants in WHHL rabbits: a mechanism genetically distinci from the low density lipoprotein receptor. Proc. Nail. Acad. Sci. USA. 79:3623-3627.
-
(1982)
Proc. Nail. Acad. Sci. USA
, vol.79
, pp. 3623-3627
-
-
Kita, T.1
Goldstein, J.L.2
Brown, M.S.3
Watanabe, Y.4
Hornick, C.A.5
Havel, R.J.6
-
5
-
-
0028273560
-
Role of hepatic lipase in the uptake and processing of chylomicrons remnants in rat liver
-
Shafi, S., S.E. Brady, A. Bensadoun, and R.J. Havel. 1994. Role of hepatic lipase in the uptake and processing of chylomicrons remnants in rat liver. J. Lipid. Res. 35:709-720.
-
(1994)
J. Lipid. Res.
, vol.35
, pp. 709-720
-
-
Shafi, S.1
Brady, S.E.2
Bensadoun, A.3
Havel, R.J.4
-
6
-
-
0027990682
-
Secretion-capture role for apolipoprotein e in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans
-
Ji, Z.S., S. Fazio, Y.L. Lee, and R.W. Mahley. 1994. Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans. J. Biol. Chem. 269:2764-2772.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2764-2772
-
-
Ji, Z.S.1
Fazio, S.2
Lee, Y.L.3
Mahley, R.W.4
-
7
-
-
0028263619
-
Enhanced binding and uptake of remnant lipoproteins by hepatic Iipase-secreting hepatoma cells in culture
-
Ji, Z.-S., SJ. Lauer, S. Fazio, A. Bensadoun, J.M. Taylor, and R.W. Mahley. 1994. Enhanced binding and uptake of remnant lipoproteins by hepatic Iipase-secreting hepatoma cells in culture. J. Biol. Chem. 269:13429-13436.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13429-13436
-
-
Ji, Z.-S.1
Lauer, S.J.2
Fazio, S.3
Bensadoun, A.4
Taylor, J.M.5
Mahley, R.W.6
-
8
-
-
0024989691
-
Apolipoprotein e localization in rat hepalocytes by immunogold labeling of cryothin sections
-
Hamilton, R.L., J.S. Wong, L.S.S. Guo, S. Krisans, and R.J. Havel. 1990. Apolipoprotein E localization in rat hepalocytes by immunogold labeling of cryothin sections. J. Lipid Res. 31:1589-1603.
-
(1990)
J. Lipid Res.
, vol.31
, pp. 1589-1603
-
-
Hamilton, R.L.1
Wong, J.S.2
Guo, L.S.S.3
Krisans, S.4
Havel, R.J.5
-
9
-
-
0028827449
-
Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway
-
Mortimer, B.C., D.J. Beveridge, U. Martins, and T.G. Redgrave. 1995. Intracellular localization and metabolism of chylomicron remnants in the livers of low density lipoprotein receptor-deficient mice and apoE-deficient mice. Evidence for slow metabolism via an alternative apoE-dependent pathway. J. Biol. Chem. 270:28767-28776.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28767-28776
-
-
Mortimer, B.C.1
Beveridge, D.J.2
Martins, U.3
Redgrave, T.G.4
-
10
-
-
0001665337
-
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
-
Herz, J., U. Hamann, S. Rogne, O. Myklebost, H. Gausepohl, and K.K. Stanley. 1988. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor. EMBO (Eur. Mol. Biol. Organ.) J. 7:4119-4127.
-
(1988)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.7
, pp. 4119-4127
-
-
Herz, J.1
Hamann, U.2
Rogne, S.3
Myklebost, O.4
Gausepohl, H.5
Stanley, K.K.6
-
11
-
-
0028284556
-
Inhibition of hepatic chylomicron remnam uptake by gene transfer of a receptor antagonist
-
Willnow, T.E., Z. Sheng, S. Ishibashi, and J. Herz. 1994. Inhibition of hepatic chylomicron remnam uptake by gene transfer of a receptor antagonist. Science. 264:1471-1474.
-
(1994)
Science
, vol.264
, pp. 1471-1474
-
-
Willnow, T.E.1
Sheng, Z.2
Ishibashi, S.3
Herz, J.4
-
12
-
-
0029079403
-
Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo
-
Willnow, T.E., S.A. Armstrong, R.E. Hammer, and J. Herz. 1995. Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo. Proc. Natl. Acad. Sci. USA. 92: 4537-4541.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4537-4541
-
-
Willnow, T.E.1
Armstrong, S.A.2
Hammer, R.E.3
Herz, J.4
-
13
-
-
0027306114
-
2-macroglobulin receptor in chylomicron remnant removal in the mouse in vivo
-
2-macroglobulin receptor in chylomicron remnant removal in the mouse in vivo. J. Biol. Chem. 268:15804-15811.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15804-15811
-
-
Choi, S.Y.1
Cooper, A.D.2
-
14
-
-
0029076825
-
Initial hepatic removal of chylomicron remnants is unaffected hut endocytosis is delayed in mice lacking the low density lipoprotein receptor
-
Hez, J., S.Q. Qiu, A. Oesterle, H.V. DeSilva, S. Shafi, and R.J. Havel. 1995. Initial hepatic removal of chylomicron remnants is unaffected hut endocytosis is delayed in mice lacking the low density lipoprotein receptor. Proc. Natl. Acad. Sci. USA. 92:4611-4615.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4611-4615
-
-
Hez, J.1
Qiu, S.Q.2
Oesterle, A.3
DeSilva, H.V.4
Shafi, S.5
Havel, R.J.6
-
15
-
-
0028284381
-
Effect of the 39-kD receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in the rat
-
Mokuno, H., S. Brady, L. Kotite, J. Herz, and R.J. Havel, 1994. Effect of the 39-kD receptor-associated protein on the hepatic uptake and endocytosis of chylomicron remnants and low density lipoproteins in the rat. J. Biol. Chem. 269:13238-13243.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13238-13243
-
-
Mokuno, H.1
Brady, S.2
Kotite, L.3
Herz, J.4
Havel, R.J.5
-
16
-
-
0026439778
-
LDL receptor-related protein internalizes and degrades uPA/PAI-1 complexes and is essential for embryo implantation
-
Herz, J., D.E. Clouthier, and R.E. Hammer. 1992. LDL receptor-related protein internalizes and degrades uPA/PAI-1 complexes and is essential for embryo implantation. Cell. 71:411-421.
-
(1992)
Cell
, vol.71
, pp. 411-421
-
-
Herz, J.1
Clouthier, D.E.2
Hammer, R.E.3
-
17
-
-
0027229924
-
Correction: LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation
-
Herz, J., D.E. Clouthier, and R.E. Hammer. 1993. Correction: LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell. 73:428.
-
(1993)
Cell
, vol.73
, pp. 428
-
-
Herz, J.1
Clouthier, D.E.2
Hammer, R.E.3
-
18
-
-
0028326257
-
Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL reccplor-relaled protein
-
Yen, F.T., CJ. Mann, L.M. Guermani, N.F. Hannouchc, N. Hubert, C.A. Hornick, V.M. Bordeau, G. Agnani, and B.E. Bihain. 1994. Identification of a lipolysis-stimulated receptor that is distinct from the LDL receptor and the LDL reccplor-relaled protein. Biochemistry. 33:1172-1180.
-
(1994)
Biochemistry
, vol.33
, pp. 1172-1180
-
-
Yen, F.T.1
Mann, C.J.2
Guermani, L.M.3
Hannouchc, N.F.4
Hubert, N.5
Hornick, C.A.6
Bordeau, V.M.7
Agnani, G.8
Bihain, B.E.9
-
19
-
-
0029155706
-
Lnducible gene targeting in mice
-
Kühn, R., F. Schwenk, M. Aguet, and K. Rajewsky. I995. lnducible gene targeting in mice. Science. 269:1427-1429.
-
(1995)
Science
, vol.269
, pp. 1427-1429
-
-
Kühn, R.1
Schwenk, F.2
Aguet, M.3
Rajewsky, K.4
-
20
-
-
0029043548
-
Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: A molecular switch for control of gene expression
-
Anton, M., and F.L. Graham 1995. Site-specific recombination mediated by an adenovirus vector expressing the Cre recombinase protein: a molecular switch for control of gene expression. J. Virol. 69:4600-4606.
-
(1995)
J. Virol.
, vol.69
, pp. 4600-4606
-
-
Anton, M.1
Graham, F.L.2
-
21
-
-
0029959746
-
Sustained somatic gene inactivalion by viral transfer of Cre recombinase
-
Rohlmann, A., M. Gotthardt, T.E. Willnow, R.H. Hammer, and J. Herz. 1996. Sustained somatic gene inactivalion by viral transfer of Cre recombinase. Nat. Biotech. 14:1562-1565.
-
(1996)
Nat. Biotech.
, vol.14
, pp. 1562-1565
-
-
Rohlmann, A.1
Gotthardt, M.2
Willnow, T.E.3
Hammer, R.H.4
Herz, J.5
-
22
-
-
0003799070
-
-
Cold Spring Harbor Laboratory Press, New York
-
Hogan, B., R. Beddingion, F. Constantini, and E. Lacy. 1994. Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York. 497 pp.
-
(1994)
Manipulating the Mouse Embryo: A Laboratory Manual
-
-
Hogan, B.1
Beddingion, R.2
Constantini, F.3
Lacy, E.4
-
24
-
-
0027409026
-
Adenovirus-mediated transfer of low density lipoprolein receptor gene acutely accelerates cholesterol clearance in normal mice
-
Herz, J., and R.D. Gerard. 1993. Adenovirus-mediated transfer of low density lipoprolein receptor gene acutely accelerates cholesterol clearance in normal mice. Proc. Natl. Acaci. Sci. USA. 90:2812-2816.
-
(1993)
Proc. Natl. Acaci. Sci. USA
, vol.90
, pp. 2812-2816
-
-
Herz, J.1
Gerard, R.D.2
-
25
-
-
0026725757
-
Severe hypcrcholesterolcmia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
-
Plump, A.S., J.D. Smith, T. Hayek. K. Aalto-Setälä. A. Walsh. J.G. Verstuyft, E.M. Rubin, and J.L. Breslow. 1992. Severe hypcrcholesterolcmia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell. 71:343-353.
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
Aalto-Setälä, K.4
Walsh, A.5
Verstuyft, J.G.6
Rubin, E.M.7
Breslow, J.L.8
-
26
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang, S.H., R.L. Reddick, J.A. Piedrahita, and N. Maeda, 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 258:468-471.
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
27
-
-
0002495086
-
Structure and metabolism of plasma lipoproteins
-
C.R. Scriver. A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill, New York
-
Havel, R.J., and J.P. Kane. 1989. Structure and metabolism of plasma lipoproteins. In The Metabolic Basis of Inherited Disease. C.R. Scriver. A.L. Beaudet, W.S. Sly, and D. Valle, editors. McGraw-Hill, New York. 1129-1138.
-
(1989)
The Metabolic Basis of Inherited Disease
, pp. 1129-1138
-
-
Havel, R.J.1
Kane, J.P.2
-
28
-
-
0027094799
-
Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins
-
Chan, L. 1992. Apolipoprotein B, the major protein component of triglyceride-rich and low density lipoproteins. J. Biol. Chem. 267.25621-25624.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 25621-25624
-
-
Chan, L.1
-
29
-
-
0024373365
-
The molecular and cell biology of apolipoprotein-B
-
Scott, J. 1989. The molecular and cell biology of apolipoprotein-B. Mol. Biol. Med. 6:65-80.
-
(1989)
Mol. Biol. Med.
, vol.6
, pp. 65-80
-
-
Scott, J.1
-
30
-
-
0025808746
-
The lowdensity lipoprotein receptor-related protein: Double agent or decoy?
-
Brown, M.S., J. Hen, R.C. Kowal, and J.L. Goldstein. 1991. The lowdensity lipoprotein receptor-related protein: double agent or decoy? Curr. Opin. Lipidol. 2:65-72.
-
(1991)
Curr. Opin. Lipidol.
, vol.2
, pp. 65-72
-
-
Brown, M.S.1
Hen, J.2
Kowal, R.C.3
Goldstein, J.L.4
-
31
-
-
0029767838
-
Ligand-activated site-specific recombination in micc
-
Feil, R., J. Brocard, B. Mascrez, M. LeMeur, D. Metzger, and P. Chambon. 1996. Ligand-activated site-specific recombination in micc. Proc. Natl. Acal. Sci. USA. 93:10887-10890.
-
(1996)
Proc. Natl. Acal. Sci. USA
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
LeMeur, M.4
Metzger, D.5
Chambon, P.6
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