Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2

Journal of Biological Chemistry

Volumn 280, Issue 26, 2005, Pages 25242-25249

  Lee, Peter C W ^a   Sever, Navdar ^a   Debose Boyd, Russell A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BIOLOGICAL MEMBRANES; BIOLOGICAL ORGANS; CHOLESTEROL; LIPIDS; MUTAGENESIS; PROTEINS; SYNTHESIS (CHEMICAL);

CHINESE HAMSTER OVARY CELLS; ENDOPLASMIC RETICULUM (ER); HOMEOSTATIS; STEROL REGULATORY ELEMENT-BINDING PROTEIN (SREBP);

CELLS;

25 HYDROXYCHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEMBRANE PROTEIN; OXIDOREDUCTASE; OXYSTEROL; PROTEIN INSIG 1; PROTEIN INSIG 2; PROTEIN SCAP; STEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ISOLATION; CHO CELL; CHOLESTEROL SYNTHESIS; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME DEGRADATION; FEEDBACK SYSTEM; GAMMA IRRADIATION; HOMEOSTASIS; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; UBIQUITINATION;

ANIMALS; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CHO CELLS; CHOLESTEROL; CRICETINAE; DNA-BINDING PROTEINS; DRUG RESISTANCE; ENDOPLASMIC RETICULUM; HYDROXYCHOLESTEROLS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; MEMBRANE PROTEINS; MUTAGENESIS; MUTATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROLS; SUBCELLULAR FRACTIONS; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSFECTION; UBIQUITIN;

ANIMALIA; CRICETULUS GRISEUS;

EID: 21644479920     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502989200     Document Type: Article

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