Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain

Molecular Cell

Volumn 11, Issue 1, 2003, Pages 25-33

  Sever, Navdar ^a   Yang, Tong ^a   Brown, Michael S ^a   Goldstein, Joseph L ^a   DeBose Boyd, Russell A ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; COMPACTIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEVALONIC ACID; PROTEIN; PROTEIN INSIG 1; STEROL; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN CLEAVAGE ACTIVATING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME DEGRADATION; FEEDBACK SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANIMALIA;

EID: 0037245750     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(02)00822-5     Document Type: Article

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