메뉴 건너뛰기




Volumn 3, Issue 6, 2004, Pages 567-580

The dark side of light: The damaging effects of UV rays and the protective efforts of MAP kinase signaling in the epidermis

Author keywords

Keratinocyte; MAPK; Oncogene; Tumor suppressor; UV radiation

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

EID: 2342561098     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2004.02.012     Document Type: Short Survey
Times cited : (28)

References (189)
  • 1
    • 0020565091 scopus 로고
    • Photocarcinogenesis, skin cancer, and aging
    • Epstein J.H. Photocarcinogenesis, skin cancer, and aging. J. Am. Acad. Dermatol. 9:1983;487-502
    • (1983) J. Am. Acad. Dermatol. , vol.9 , pp. 487-502
    • Epstein, J.H.1
  • 2
    • 0027669972 scopus 로고
    • Frequency of ultraviolet radiation-induced mutation at the hprt locus in repair-proficient murine fibroblasts transfected with the denV gene of bacteriophage T4
    • Kusewitt D.F., Budge C.L., Anderson M.M., Ryan S.L., Ley R.D. Frequency of ultraviolet radiation-induced mutation at the hprt locus in repair-proficient murine fibroblasts transfected with the denV gene of bacteriophage T4. Photochem. Photobiol. 58:1993;450-454
    • (1993) Photochem. Photobiol. , vol.58 , pp. 450-454
    • Kusewitt, D.F.1    Budge, C.L.2    Anderson, M.M.3    Ryan, S.L.4    Ley, R.D.5
  • 4
    • 0016299016 scopus 로고
    • The wavelengths in sunlight effective in producing skin cancer: A theoretical analysis
    • Setlow R.B. The wavelengths in sunlight effective in producing skin cancer: a theoretical analysis. Proc. Natl. Acad. Sci. U.S.A. 71:1974;3363-3366
    • (1974) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 3363-3366
    • Setlow, R.B.1
  • 6
    • 0033372068 scopus 로고    scopus 로고
    • Skin cancer and solar UV radiation
    • de Gruijl F.R. Skin cancer and solar UV radiation. Eur. J. Cancer. 35:1999;2003-2009
    • (1999) Eur. J. Cancer , vol.35 , pp. 2003-2009
    • De Gruijl, F.R.1
  • 7
    • 0033256049 scopus 로고    scopus 로고
    • Environmental factors in nonmelanoma and melanoma skin cancer
    • Woodhead A.D., Setlow R.B., Tanaka M. Environmental factors in nonmelanoma and melanoma skin cancer. J. Epidemiol. 9:1999;S102-S114
    • (1999) J. Epidemiol. , vol.9 , pp. 102-S114
    • Woodhead, A.D.1    Setlow, R.B.2    Tanaka, M.3
  • 8
    • 0028284693 scopus 로고
    • Nonmelanoma skin cancer in the United States: Incidence
    • Miller D.L., Weinstock M.A. Nonmelanoma skin cancer in the United States: incidence. J. Am. Acad. Dermatol. 30:1994;774-778
    • (1994) J. Am. Acad. Dermatol. , vol.30 , pp. 774-778
    • Miller, D.L.1    Weinstock, M.A.2
  • 9
    • 0026009528 scopus 로고
    • Incidence of nonmelanoma skin cancer
    • Urbach F. Incidence of nonmelanoma skin cancer. Dermatol. Clin. 9:1991;751-755
    • (1991) Dermatol. Clin. , vol.9 , pp. 751-755
    • Urbach, F.1
  • 10
    • 0033923503 scopus 로고    scopus 로고
    • Photocarcinogenesis: UVA vs. UVB
    • de Gruijl F.R. Photocarcinogenesis: UVA vs. UVB. Methods Enzymol. 319:2000;359-366
    • (2000) Methods Enzymol. , vol.319 , pp. 359-366
    • De Gruijl, F.R.1
  • 11
    • 0023352287 scopus 로고
    • Action spectra for the induction of pyrimidine(6-4)pyrimidone photoproducts and cyclobutane pyrimidine dimers in normal human skin fibroblasts
    • Rosenstein B.S., Mitchell D.L. Action spectra for the induction of pyrimidine(6-4)pyrimidone photoproducts and cyclobutane pyrimidine dimers in normal human skin fibroblasts. Photochem. Photobiol. 45:1987;775-780
    • (1987) Photochem. Photobiol. , vol.45 , pp. 775-780
    • Rosenstein, B.S.1    Mitchell, D.L.2
  • 14
    • 0028197170 scopus 로고
    • Free radicals in cutaneous biology
    • Darr D., Fridovich I. Free radicals in cutaneous biology. J. Invest. Dermatol. 102:1994;671-675
    • (1994) J. Invest. Dermatol. , vol.102 , pp. 671-675
    • Darr, D.1    Fridovich, I.2
  • 15
    • 0024049251 scopus 로고
    • The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells
    • Mitchell D.L. The relative cytotoxicity of (6-4) photoproducts and cyclobutane dimers in mammalian cells. Photochem. Photobiol. 48:1988;51-57
    • (1988) Photochem. Photobiol. , vol.48 , pp. 51-57
    • Mitchell, D.L.1
  • 19
    • 0030838767 scopus 로고    scopus 로고
    • The molecular basis of nonmelanoma skin cancer: New understanding
    • Grossman D., Leffell D.J. The molecular basis of nonmelanoma skin cancer: new understanding. Arch. Dermatol. 133:1997;1263-1270
    • (1997) Arch. Dermatol. , vol.133 , pp. 1263-1270
    • Grossman, D.1    Leffell, D.J.2
  • 20
    • 0029036342 scopus 로고
    • The specificity of p53 mutation spectra in sunlight induced human cancers
    • Daya-Grosjean L., Dumaz N., Sarasin A. The specificity of p53 mutation spectra in sunlight induced human cancers. J. Photochem. Photobiol. B. 28:1995;115-124
    • (1995) J. Photochem. Photobiol. B , vol.28 , pp. 115-124
    • Daya-Grosjean, L.1    Dumaz, N.2    Sarasin, A.3
  • 22
    • 0025203297 scopus 로고
    • Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma
    • Alcalay J., Freeman S.E., Goldberg L.H., Wolf J.E. Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma. J. Invest. Dermatol. 95:1990;506-509
    • (1990) J. Invest. Dermatol. , vol.95 , pp. 506-509
    • Alcalay, J.1    Freeman, S.E.2    Goldberg, L.H.3    Wolf, J.E.4
  • 24
    • 0014421995 scopus 로고
    • Defective repair replication of DNA in xeroderma pigmentosum
    • Cleaver J.E. Defective repair replication of DNA in xeroderma pigmentosum. Nature. 218:1968;652-656
    • (1968) Nature , vol.218 , pp. 652-656
    • Cleaver, J.E.1
  • 25
    • 0015982924 scopus 로고
    • Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair
    • Robbins J.H., Kraemer K.H., Lutzner M.A., Festoff B.W., Coon H.G. Xeroderma pigmentosum. An inherited diseases with sun sensitivity, multiple cutaneous neoplasms, and abnormal DNA repair. Ann. Intern. Med. 80:1974;221-248
    • (1974) Ann. Intern. Med. , vol.80 , pp. 221-248
    • Robbins, J.H.1    Kraemer, K.H.2    Lutzner, M.A.3    Festoff, B.W.4    Coon, H.G.5
  • 26
    • 0031022619 scopus 로고    scopus 로고
    • Sunlight and skin cancer: Another link revealed
    • Kraemer K.H. Sunlight and skin cancer: another link revealed. Proc. Natl. Acad. Sci. U.S.A. 94:1997;11-14
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 11-14
    • Kraemer, K.H.1
  • 27
    • 0035941996 scopus 로고    scopus 로고
    • Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: A randomised study. Xeroderma Pigmentosum Study Group
    • Yarosh D., Klein J., O'Connor A., Hawk J., Rafal E., Wolf P. Effect of topically applied T4 endonuclease V in liposomes on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma Pigmentosum Study Group. Lancet. 357:2001;926-929
    • (2001) Lancet , vol.357 , pp. 926-929
    • Yarosh, D.1    Klein, J.2    O'Connor, A.3    Hawk, J.4    Rafal, E.5    Wolf, P.6
  • 28
    • 0029115193 scopus 로고
    • Ultraviolet-B-induced apoptosis of keratinocytes: Evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells
    • Schwarz A., Bhardwaj R., Aragane Y., Mahnke K., Riemann H., Metze D., Luger T.A., Schwarz T. Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-alpha in the formation of sunburn cells. J. Invest. Dermatol. 104:1995;922-927
    • (1995) J. Invest. Dermatol. , vol.104 , pp. 922-927
    • Schwarz, A.1    Bhardwaj, R.2    Aragane, Y.3    Mahnke, K.4    Riemann, H.5    Metze, D.6    Luger, T.A.7    Schwarz, T.8
  • 30
    • 0019598992 scopus 로고
    • Relationship of the cell cycle to sunburn cell formation
    • Danno K., Takigawa M., Horio T. Relationship of the cell cycle to sunburn cell formation. Photochem. Photobiol. 34:1981;203-206
    • (1981) Photochem. Photobiol. , vol.34 , pp. 203-206
    • Danno, K.1    Takigawa, M.2    Horio, T.3
  • 32
    • 0035182390 scopus 로고    scopus 로고
    • Ultraviolet light induced injury: Immunological and inflammatory effects
    • Clydesdale G.J., Dandie G.W., Muller H.K. Ultraviolet light induced injury: immunological and inflammatory effects. Immunol. Cell. Biol. 79:2001;547-568
    • (2001) Immunol. Cell. Biol. , vol.79 , pp. 547-568
    • Clydesdale, G.J.1    Dandie, G.W.2    Muller, H.K.3
  • 34
    • 0000516293 scopus 로고    scopus 로고
    • Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair
    • Hwang B.J., Ford J.M., Hanawalt P.C., Chu G. Expression of the p48 xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair. Proc. Natl. Acad. Sci. U.S.A. 96:1999;424-428
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 424-428
    • Hwang, B.J.1    Ford, J.M.2    Hanawalt, P.C.3    Chu, G.4
  • 35
    • 0036490207 scopus 로고    scopus 로고
    • A nucleotide excision repair master-switch: P53 regulated coordinate induction of global genomic repair genes
    • Amundson S.A., Patterson A., Do K.T., Fornace A.J.J. A nucleotide excision repair master-switch: p53 regulated coordinate induction of global genomic repair genes. Cancer Biol. Ther. 1:2002;145-149
    • (2002) Cancer Biol. Ther. , vol.1 , pp. 145-149
    • Amundson, S.A.1    Patterson, A.2    Do, K.T.3    Fornace, A.J.J.4
  • 37
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of UV-type DNA damage
    • Smith M.L., Chen I.T., Zhan Q., O'Connor P.M., Fornace A.J. Jr. Involvement of the p53 tumor suppressor in repair of UV-type DNA damage. Oncogene. 10:1995;1053-1059
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3    O'Connor, P.M.4    Fornace Jr., A.J.5
  • 38
    • 0030119061 scopus 로고    scopus 로고
    • The two faces of tumor suppressor p53
    • Smith M.L., Fornace A.J. Jr. The two faces of tumor suppressor p53. Am. J. Pathol. 148:1996;1019-1022
    • (1996) Am. J. Pathol. , vol.148 , pp. 1019-1022
    • Smith, M.L.1    Fornace Jr., A.J.2
  • 39
    • 0036270993 scopus 로고    scopus 로고
    • DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis
    • Bernstein C., Bernstein H., Payne C.M., Garewal H. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis. Mutat. Res. 511:2002;145-178
    • (2002) Mutat. Res. , vol.511 , pp. 145-178
    • Bernstein, C.1    Bernstein, H.2    Payne, C.M.3    Garewal, H.4
  • 41
    • 0027197097 scopus 로고
    • Cyclobutane pryrimidine dimers in UV-DNA induce release of soluble mediators which activate the human immunodeficiency virus promoter
    • Yarosh D.B., Alas L., Kibitel J., O'Connor A., Carrier F., Fornace A.J. Jr. Cyclobutane pryrimidine dimers in UV-DNA induce release of soluble mediators which activate the human immunodeficiency virus promoter. J. Invest. Dermatol. 100:1993;790-794
    • (1993) J. Invest. Dermatol. , vol.100 , pp. 790-794
    • Yarosh, D.B.1    Alas, L.2    Kibitel, J.3    O'Connor, A.4    Carrier, F.5    Fornace Jr., A.J.6
  • 42
    • 0030785521 scopus 로고    scopus 로고
    • Enhancement of DNA repair in human skin cells by thymidine dinucleotides: Evidence for a p53-mediated mammalian SOS response
    • Eller M.S., Maeda T., Magnoni C., Atwal D., Gilchrest B.A. Enhancement of DNA repair in human skin cells by thymidine dinucleotides: evidence for a p53-mediated mammalian SOS response. Proc. Natl. Acad. Sci. U.S.A. 94:1997;12627-12632
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 12627-12632
    • Eller, M.S.1    Maeda, T.2    Magnoni, C.3    Atwal, D.4    Gilchrest, B.A.5
  • 43
    • 0027363407 scopus 로고
    • NF-κB activation by ultraviolet light not dependent on a nuclear signal
    • Devary Y., Rosette C., DiDonato J.A., Karin M. NF-κB activation by ultraviolet light not dependent on a nuclear signal. Science. 261:1993;1442-1445
    • (1993) Science , vol.261 , pp. 1442-1445
    • Devary, Y.1    Rosette, C.2    Didonato, J.A.3    Karin, M.4
  • 47
    • 17844394391 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase activation in UV-induced signal transduction
    • A.M. Bode, Z. Dong, Mitogen-activated protein kinase activation in UV-induced signal transduction, Sci. STKE, 2003, RE2.
    • (2003) Sci. STKE
    • Bode, A.M.1    Dong, Z.2
  • 48
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis J.M., Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol. Rev. 81:2001;807-869
    • (2001) Physiol. Rev. , vol.81 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 49
  • 50
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development
    • Ip Y.T., Davis R.J. Signal transduction by the c-Jun N-terminal kinase (JNK)-from inflammation to development. Curr. Opin. Cell. Biol. 10:1998;205-219
    • (1998) Curr. Opin. Cell. Biol. , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 51
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis J.M., Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays. 18:1996;567-577
    • (1996) Bioessays , vol.18 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 54
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard B., Hibi M., Wu I.H., Barrett T., Su B., Deng T., Karin M., Davis R.J. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell. 76:1994;1025-1037
    • (1994) Cell , vol.76 , pp. 1025-1037
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 56
    • 0033567291 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathways
    • Tibbles L.A., Woodgett J.R. The stress-activated protein kinase pathways. Cell. Mol. Life Sci. 55:1999;1230-1254
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 1230-1254
    • Tibbles, L.A.1    Woodgett, J.R.2
  • 57
    • 0030866897 scopus 로고    scopus 로고
    • Activation mechanism of the MAP kinase ERK2 by dual phosphorylation
    • Canagarajah B.J., Khokhlatchev A., Cobb M.H., Goldsmith E.J. Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell. 90:1997;859-869
    • (1997) Cell , vol.90 , pp. 859-869
    • Canagarajah, B.J.1    Khokhlatchev, A.2    Cobb, M.H.3    Goldsmith, E.J.4
  • 58
    • 0026539931 scopus 로고
    • The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product
    • Crews C.M., Alessandrini A., Erikson R.L. The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science. 258:1992;478-480
    • (1992) Science , vol.258 , pp. 478-480
    • Crews, C.M.1    Alessandrini, A.2    Erikson, R.L.3
  • 59
    • 0027217533 scopus 로고
    • Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2
    • Zheng C.F., Guan K.L. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2. J. Biol. Chem. 268:1993;11435-11439
    • (1993) J. Biol. Chem. , vol.268 , pp. 11435-11439
    • Zheng, C.F.1    Guan, K.L.2
  • 62
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard B., Raingeaud J., Barrett T., Wu I.H., Han J., Ulevitch R.J., Davis R.J. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science. 267:1995;682-685
    • (1995) Science , vol.267 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 63
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway
    • Coso O.A., Chiariello M., Yu J.C., Teramoto H., Crespo P., Xu N., Miki T., Gutkind J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell. 81:1995;1137-1146
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 66
    • 0028880006 scopus 로고
    • Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
    • Xia Z., Dickens M., Raingeaud J., Davis R.J., Greenberg M.E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science. 270:1995;1326-1331
    • (1995) Science , vol.270 , pp. 1326-1331
    • Xia, Z.1    Dickens, M.2    Raingeaud, J.3    Davis, R.J.4    Greenberg, M.E.5
  • 67
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L., Karin M. Mammalian MAP kinase signalling cascades. Nature. 410:2001;37-40
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 68
    • 0036242247 scopus 로고    scopus 로고
    • Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence
    • Wang W., Chen J.X., Liao R., Deng Q., Zhou J.J., Huang S., Sun P. Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol. Cell. Biol. 22:2002;3389-3403
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3389-3403
    • Wang, W.1    Chen, J.X.2    Liao, R.3    Deng, Q.4    Zhou, J.J.5    Huang, S.6    Sun, P.7
  • 69
    • 0036315395 scopus 로고    scopus 로고
    • The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor
    • Iordanov M.S., Choi R.J., Ryabinina O.P., Dinh T.H., Bright R.K., Magun B.E. The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor. Mol. Cell. Biol. 22:2002;5380-5394
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5380-5394
    • Iordanov, M.S.1    Choi, R.J.2    Ryabinina, O.P.3    Dinh, T.H.4    Bright, R.K.5    Magun, B.E.6
  • 70
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin A.W., Barradas M., Stone J.C., van Aelst L., Serrano M., Lowe S.W. Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev. 12:1998;3008-3019
    • (1998) Genes Dev. , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    Van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 71
    • 1842429927 scopus 로고    scopus 로고
    • Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation
    • Hildesheim J., Belova G.I., Tyner S.D., Zhou X., Vardanian L., Fornace A.J. Gadd45a regulates matrix metalloproteinases by suppressing DeltaNp63alpha and beta-catenin via p38 MAP kinase and APC complex activation. Oncogene. 23:2004;1829-1837
    • (2004) Oncogene , vol.23 , pp. 1829-1837
    • Hildesheim, J.1    Belova, G.I.2    Tyner, S.D.3    Zhou, X.4    Vardanian, L.5    Fornace, A.J.6
  • 72
    • 0036023401 scopus 로고    scopus 로고
    • Gadd45a: An elusive yet attractive candidate gene in pancreatic cancer
    • Hildesheim J., Fornace A.J.J. Gadd45a: an elusive yet attractive candidate gene in pancreatic cancer. Clin. Cancer Res. 8:2002;2475-2479
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2475-2479
    • Hildesheim, J.1    Fornace, A.J.J.2
  • 73
    • 0037025296 scopus 로고    scopus 로고
    • Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation
    • She Q.B., Ma W.Y., Zhong S., Dong Z. Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation. J. Biol. Chem. 277:2002;24039-24048
    • (2002) J. Biol. Chem. , vol.277 , pp. 24039-24048
    • She, Q.B.1    Ma, W.Y.2    Zhong, S.3    Dong, Z.4
  • 74
    • 0037186149 scopus 로고    scopus 로고
    • Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20
    • She Q.B., Ma W.Y., Dong Z. Role of MAP kinases in UVB-induced phosphorylation of p53 at serine 20. Oncogene. 21:2000;1580-1589
    • (2000) Oncogene , vol.21 , pp. 1580-1589
    • She, Q.B.1    Ma, W.Y.2    Dong, Z.3
  • 75
    • 1442299046 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase inhibitor protects the epidermis against the acute damaging effects of ultraviolet irradiation by blocking apoptosis and inflammatory responses
    • Hildesheim J., Awwad R.T., Fornace A.J. p38 mitogen-activated protein kinase inhibitor protects the epidermis against the acute damaging effects of ultraviolet irradiation by blocking apoptosis and inflammatory responses. J. Invest. Dermatol. 122:2004;497-502
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 497-502
    • Hildesheim, J.1    Awwad, R.T.2    Fornace, A.J.3
  • 78
    • 0032959647 scopus 로고    scopus 로고
    • Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal to stimulate DNA synthesis
    • Treinies I., Paterson H.F., Hooper S., Marshall R.andC.J. Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis. Mol. Cell. Biol. 19:1999;321-329
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 321-329
    • Treinies, I.1    Paterson, H.F.2    Hooper, S.3    Marshall, R.andC.J.4
  • 79
    • 0034617077 scopus 로고    scopus 로고
    • ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation
    • She Q.B., Chen N., Dong Z. ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiation. J. Biol. Chem. 275:2000;20444-20449
    • (2000) J. Biol. Chem. , vol.275 , pp. 20444-20449
    • She, Q.B.1    Chen, N.2    Dong, Z.3
  • 80
    • 0034142034 scopus 로고    scopus 로고
    • The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
    • Shieh S.Y., Ahn J., Tamai K., Taya Y., Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 14:2000;289-300
    • (2000) Genes Dev. , vol.14 , pp. 289-300
    • Shieh, S.Y.1    Ahn, J.2    Tamai, K.3    Taya, Y.4    Prives, C.5
  • 82
    • 0032514967 scopus 로고    scopus 로고
    • A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
    • Takekawa M., Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell. 95:1998;521-530
    • (1998) Cell , vol.95 , pp. 521-530
    • Takekawa, M.1    Saito, H.2
  • 83
    • 0036275374 scopus 로고    scopus 로고
    • Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding
    • Mita H., Tsutsui J., Takekawa M., Witten E.A., Saito H. Regulation of MTK1/MEKK4 kinase activity by its N-terminal autoinhibitory domain and GADD45 binding. Mol. Cell. Biol. 22:2002;4544-4555
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4544-4555
    • Mita, H.1    Tsutsui, J.2    Takekawa, M.3    Witten, E.A.4    Saito, H.5
  • 84
    • 0026097775 scopus 로고
    • Sequence and expression of a cDNA encoding MyD118: A novel myeloid differentiation primary response gene induced by multiple cytokines
    • Abdollahi A., Lord K.A., Hoffman-Liebermann B., Liebermann D. Sequence and expression of a cDNA encoding MyD118: a novel myeloid differentiation primary response gene induced by multiple cytokines. Oncogene. 6:1991;165-167
    • (1991) Oncogene , vol.6 , pp. 165-167
    • Abdollahi, A.1    Lord, K.A.2    Hoffman-Liebermann, B.3    Liebermann, D.4
  • 85
    • 0033609908 scopus 로고    scopus 로고
    • A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth
    • Nakayama K., Hara T., Hibi M., Hirano T., Miyajima A. A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth. J. Biol. Chem. 274:1999;24766-24772
    • (1999) J. Biol. Chem. , vol.274 , pp. 24766-24772
    • Nakayama, K.1    Hara, T.2    Hibi, M.3    Hirano, T.4    Miyajima, A.5
  • 86
    • 0033517293 scopus 로고    scopus 로고
    • CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control
    • Zhang W., Bae I., Krishnaraju K., Azam N., Fan W., Smith K., Hoffman B., Liebermann D.A. CR6: a third member in the MyD118 and Gadd45 gene family which functions in negative growth control. Oncogene. 18:1999;4899-4907
    • (1999) Oncogene , vol.18 , pp. 4899-4907
    • Zhang, W.1    Bae, I.2    Krishnaraju, K.3    Azam, N.4    Fan, W.5    Smith, K.6    Hoffman, B.7    Liebermann, D.A.8
  • 87
    • 0038246249 scopus 로고    scopus 로고
    • Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a
    • Bulavin D.V., Kovalsky O., Hollander M.C., Fornace A.J.J. Loss of oncogenic H-ras-induced cell cycle arrest and p38 mitogen-activated protein kinase activation by disruption of Gadd45a. Mol. Cell. Biol. 23:2003;3859-3871
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 3859-3871
    • Bulavin, D.V.1    Kovalsky, O.2    Hollander, M.C.3    Fornace, A.J.J.4
  • 88
    • 0027768579 scopus 로고
    • Braking the cycle
    • Hunter T. Braking the cycle. Cell. 75:1993;839-841
    • (1993) Cell , vol.75 , pp. 839-841
    • Hunter, T.1
  • 89
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins
    • Sherr C.J. Mammalian G1 cyclins. Cell. 73:1993;1059-1065
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 91
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:1993;805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 92
    • 0027301324 scopus 로고
    • Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
    • Xiong Y., Zhang H., Beach D. Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev. 7:1993;1572-1583
    • (1993) Genes Dev. , vol.7 , pp. 1572-1583
    • Xiong, Y.1    Zhang, H.2    Beach, D.3
  • 95
    • 0033529121 scopus 로고    scopus 로고
    • Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45
    • Zhan Q., Antinore M.J., Wang X.W., Carrier F., Smith M.L., Harris C.C., Fornace A.J.J. Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45. Oncogene. 18:1999;2892-2900
    • (1999) Oncogene , vol.18 , pp. 2892-2900
    • Zhan, Q.1    Antinore, M.J.2    Wang, X.W.3    Carrier, F.4    Smith, M.L.5    Harris, C.C.6    Fornace, A.J.J.7
  • 96
    • 0032960483 scopus 로고    scopus 로고
    • Induced expression of p16 and p21 proteins in UVB-irradiated human epidermis and cultured keratinocytes
    • Ahmed N.U., Ueda M., Ichihashi M. Induced expression of p16 and p21 proteins in UVB-irradiated human epidermis and cultured keratinocytes. J. Dermatol. Sci. 19:1999;175-181
    • (1999) J. Dermatol. Sci. , vol.19 , pp. 175-181
    • Ahmed, N.U.1    Ueda, M.2    Ichihashi, M.3
  • 97
    • 0033200066 scopus 로고    scopus 로고
    • Ultraviolet radiation induces p16CDKN2A expression in human skin
    • Pavey S., Conroy S., Russell T., Gabrielli B. Ultraviolet radiation induces p16CDKN2A expression in human skin. Cancer Res. 59:1999;4185-4189
    • (1999) Cancer Res. , vol.59 , pp. 4185-4189
    • Pavey, S.1    Conroy, S.2    Russell, T.3    Gabrielli, B.4
  • 98
    • 0027769876 scopus 로고
    • A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M., Hannon G.J., Beach D. A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature. 366:1993;704-707
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 100
    • 0028275733 scopus 로고
    • Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
    • Nobori T., Miura K., Wu D.J., Lois A., Takabayashi K., Carson D.A. Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers. Nature. 368:1994;753-756
    • (1994) Nature , vol.368 , pp. 753-756
    • Nobori, T.1    Miura, K.2    Wu, D.J.3    Lois, A.4    Takabayashi, K.5    Carson, D.A.6
  • 101
    • 0037075887 scopus 로고    scopus 로고
    • Cyclin D-dependent kinases, INK4 inhibitors and cancer
    • Ortega S., Malumbres M., Barbacid M. Cyclin D-dependent kinases, INK4 inhibitors and cancer. Biochim. Biophys. Acta. 1602:2002;73-87
    • (2002) Biochim. Biophys. Acta , vol.1602 , pp. 73-87
    • Ortega, S.1    Malumbres, M.2    Barbacid, M.3
  • 102
    • 0142084976 scopus 로고    scopus 로고
    • Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint
    • Goloudina A., Yamaguchi H., Chervyakova D.B., Appella E., Fornace A.J.J., Bulavin D.V. Regulation of human Cdc25A stability by Serine 75 phosphorylation is not sufficient to activate a S phase checkpoint. Cell Cycle. 2:2003;473-478
    • (2003) Cell Cycle , vol.2 , pp. 473-478
    • Goloudina, A.1    Yamaguchi, H.2    Chervyakova, D.B.3    Appella, E.4    Fornace, A.J.J.5    Bulavin, D.V.6
  • 104
  • 106
    • 0642347221 scopus 로고    scopus 로고
    • UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis
    • Ehrhart J.C., Gosselet F.P., Culerrier R.M., Sarasin A. UVB-induced mutations in human key gatekeeper genes governing signalling pathways and consequences for skin tumourigenesis. Photochem. Photobiol. Sci. 2:2003;825-834
    • (2003) Photochem. Photobiol. Sci. , vol.2 , pp. 825-834
    • Ehrhart, J.C.1    Gosselet, F.P.2    Culerrier, R.M.3    Sarasin, A.4
  • 108
    • 0032884884 scopus 로고    scopus 로고
    • Beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer
    • Brabletz T., Jung A., Dag S., Hlubek F., Kirchner T. Beta-catenin regulates the expression of the matrix metalloproteinase-7 in human colorectal cancer. Am. J. Pathol. 155:1999;1033-1038
    • (1999) Am. J. Pathol. , vol.155 , pp. 1033-1038
    • Brabletz, T.1    Jung, A.2    Dag, S.3    Hlubek, F.4    Kirchner, T.5
  • 110
    • 0033486152 scopus 로고    scopus 로고
    • Beta-catenin signaling and cancer
    • Morin P.J. Beta-catenin signaling and cancer. Bioessays. 21:1999;1021-1030
    • (1999) Bioessays , vol.21 , pp. 1021-1030
    • Morin, P.J.1
  • 112
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O., McCormick F. Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature. 398:1999;422-426
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 113
    • 0033913603 scopus 로고    scopus 로고
    • Control of beta-catenin signaling in tumor development
    • discussion 33-5
    • Behrens J. Control of beta-catenin signaling in tumor development. Ann. N. Y. Acad. Sci. 910:2000;21-33. discussion 33-5
    • (2000) Ann. N. Y. Acad. Sci. , vol.910 , pp. 21-33
    • Behrens, J.1
  • 114
    • 0037194578 scopus 로고    scopus 로고
    • Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers
    • Takahashi M., Tsunoda T., Seiki M., Nakamura Y., Furukawa Y. Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers. Oncogene. 21:2002;5861-5867
    • (2002) Oncogene , vol.21 , pp. 5861-5867
    • Takahashi, M.1    Tsunoda, T.2    Seiki, M.3    Nakamura, Y.4    Furukawa, Y.5
  • 115
    • 0032575135 scopus 로고    scopus 로고
    • Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose radiation in A431 human squamous carcinoma cells
    • Carter S., Auer K.L., Reardon D.B., Birrer M., Fisher P.B., Valerie K., Schmidt-Ullrich R., Mikkelsen R., Dent P. Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose radiation in A431 human squamous carcinoma cells. Oncogene. 16:1998;2787-2796
    • (1998) Oncogene , vol.16 , pp. 2787-2796
    • Carter, S.1    Auer, K.L.2    Reardon, D.B.3    Birrer, M.4    Fisher, P.B.5    Valerie, K.6    Schmidt-Ullrich, R.7    Mikkelsen, R.8    Dent, P.9
  • 120
    • 0027275779 scopus 로고
    • Expression of p53 protein is an early event in ultraviolet light-induced cutaneous squamous cell carcinogenesis
    • Nagano T., Ueda M., Ichihashi M. Expression of p53 protein is an early event in ultraviolet light-induced cutaneous squamous cell carcinogenesis. Arch. Dermatol. 129:1993;1157-1161
    • (1993) Arch. Dermatol. , vol.129 , pp. 1157-1161
    • Nagano, T.1    Ueda, M.2    Ichihashi, M.3
  • 121
    • 0027969997 scopus 로고
    • Aberrations of the tumor suppressor p53 gene and p53 protein in solar keratosis in human skin
    • Taguchi M., Watanabe S., Yashima K., Murakami Y., Sekiya T., Ikeda S. Aberrations of the tumor suppressor p53 gene and p53 protein in solar keratosis in human skin. J. Invest. Dermatol. 103:1994;500-503
    • (1994) J. Invest. Dermatol. , vol.103 , pp. 500-503
    • Taguchi, M.1    Watanabe, S.2    Yashima, K.3    Murakami, Y.4    Sekiya, T.5    Ikeda, S.6
  • 129
    • 0025374041 scopus 로고
    • Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin
    • van der Schroeff J.G., Evers L.M., Boot A.J., Bos J.L. Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin. J. Invest. Dermatol. 94:1990;423-425
    • (1990) J. Invest. Dermatol. , vol.94 , pp. 423-425
    • Van Der Schroeff, J.G.1    Evers, L.M.2    Boot, A.J.3    Bos, J.L.4
  • 131
    • 0022527161 scopus 로고
    • Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis
    • Quintanilla M., Brown K., Ramsden M., Balmain A. Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis. Nature. 322:1986;78-80
    • (1986) Nature , vol.322 , pp. 78-80
    • Quintanilla, M.1    Brown, K.2    Ramsden, M.3    Balmain, A.4
  • 132
    • 0036023416 scopus 로고    scopus 로고
    • Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer
    • Yamasawa K., Nio Y., Dong M., Yamaguchi K., Itakura M. Clinicopathological significance of abnormalities in Gadd45 expression and its relationship to p53 in human pancreatic cancer. Clin. Cancer Res. 8:2002;2563-2569
    • (2002) Clin. Cancer Res. , vol.8 , pp. 2563-2569
    • Yamasawa, K.1    Nio, Y.2    Dong, M.3    Yamaguchi, K.4    Itakura, M.5
  • 133
  • 134
    • 0032161624 scopus 로고    scopus 로고
    • P63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A., Kaghad M., Wang Y., Gillett E., Fleming M.D., Dotsch V., Andrews N.C., Caput D., McKeon F. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol. Cell. 2:1998;305-316
    • (1998) Mol. Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6    Andrews, N.C.7    Caput, D.8    McKeon, F.9
  • 135
    • 0033594491 scopus 로고    scopus 로고
    • P63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills A.A., Zheng B., Wang X.J., Vogel H., Roop D.R., Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature. 398:1999;708-713
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 137
    • 0033372016 scopus 로고    scopus 로고
    • Association of p63 with proliferative potential in normal and neoplastic human keratinocytes
    • Parsa R., Yang A., McKeon F., Green H. Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J. Invest. Dermatol. 113:1999;1099-1105
    • (1999) J. Invest. Dermatol. , vol.113 , pp. 1099-1105
    • Parsa, R.1    Yang, A.2    McKeon, F.3    Green, H.4
  • 143
    • 0037377761 scopus 로고    scopus 로고
    • The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations
    • Westfall M.D., Mays D.J., Sniezek J.C., Pietenpol J.A. The Delta Np63 alpha phosphoprotein binds the p21 and 14-3-3 sigma promoters in vivo and has transcriptional repressor activity that is reduced by Hay-Wells syndrome-derived mutations. Mol. Cell. Biol. 23:2003;2264-2276
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 2264-2276
    • Westfall, M.D.1    Mays, D.J.2    Sniezek, J.C.3    Pietenpol, J.A.4
  • 144
    • 0037804687 scopus 로고    scopus 로고
    • DeltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes
    • King K.E., Ponnamperuma R.M., Yamashita T., Tokino T., Lee L.A., Young M.F., Weinberg W.C. deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes. Oncogene. 22:2003;3635-3644
    • (2003) Oncogene , vol.22 , pp. 3635-3644
    • King, K.E.1    Ponnamperuma, R.M.2    Yamashita, T.3    Tokino, T.4    Lee, L.A.5    Young, M.F.6    Weinberg, W.C.7
  • 145
    • 0034053069 scopus 로고    scopus 로고
    • Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus
    • Peifer M., Polakis P. Wnt signaling in oncogenesis and embryogenesis-a look outside the nucleus. Science. 287:2000;1606-1609
    • (2000) Science , vol.287 , pp. 1606-1609
    • Peifer, M.1    Polakis, P.2
  • 146
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis P. Wnt signaling and cancer. Genes Dev. 14:2000;1837-1851
    • (2000) Genes Dev. , vol.14 , pp. 1837-1851
    • Polakis, P.1
  • 147
    • 0037205007 scopus 로고    scopus 로고
    • The promise and perils of Wnt signaling through beta-catenin
    • Moon R.T., Bowerman B., Boutros M., Perrimon N. The promise and perils of Wnt signaling through beta-catenin. Science. 296:2002;1644-1646
    • (2002) Science , vol.296 , pp. 1644-1646
    • Moon, R.T.1    Bowerman, B.2    Boutros, M.3    Perrimon, N.4
  • 148
    • 0037309239 scopus 로고    scopus 로고
    • You Wnt some, you lose some: Oncogenes in the Wnt signaling pathway
    • van E.J.H., Barker N., Clevers H. You Wnt some, you lose some: oncogenes in the Wnt signaling pathway. Curr. Opin. Genet. Dev. 13:2003;28-33
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 28-33
    • Van, E.J.H.1    Barker, N.2    Clevers, H.3
  • 149
    • 0019362967 scopus 로고
    • Immunologic mechanisms in UV radiation carcinogenesis
    • Kripke M.L. Immunologic mechanisms in UV radiation carcinogenesis. Adv. Cancer Res. 34:1981;69-106
    • (1981) Adv. Cancer Res. , vol.34 , pp. 69-106
    • Kripke, M.L.1
  • 150
    • 0019805471 scopus 로고
    • Experimental photoimmunology: Immunologic ramifications of UV-induced carcinogenesis
    • Daynes R.A., Bernhard E.J., Gurish M.F., Lynch D.H. Experimental photoimmunology: immunologic ramifications of UV-induced carcinogenesis. J. Invest. Dermatol. 77:1981;77-85
    • (1981) J. Invest. Dermatol. , vol.77 , pp. 77-85
    • Daynes, R.A.1    Bernhard, E.J.2    Gurish, M.F.3    Lynch, D.H.4
  • 151
    • 0025205234 scopus 로고
    • Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans
    • Yoshikawa T., Rae V., Bruins-Slot W., Van den Berg J.W., Taylor J.R., Streilein J.W. Susceptibility to effects of UVB radiation on induction of contact hypersensitivity as a risk factor for skin cancer in humans. J. Invest. Dermatol. 95:1990;530-536
    • (1990) J. Invest. Dermatol. , vol.95 , pp. 530-536
    • Yoshikawa, T.1    Rae, V.2    Bruins-Slot, W.3    Van Den Berg, J.W.4    Taylor, J.R.5    Streilein, J.W.6
  • 153
    • 0026668607 scopus 로고
    • Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice
    • Kripke M.L., Cox P.A., Alas L.G., Yarosh D.B. Pyrimidine dimers in DNA initiate systemic immunosuppression in UV-irradiated mice. Proc. Natl. Acad. Sci. U.S.A. 89:1992;7516-7520
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 7516-7520
    • Kripke, M.L.1    Cox, P.A.2    Alas, L.G.3    Yarosh, D.B.4
  • 154
    • 0025337476 scopus 로고
    • Acute effects of ultraviolet radiation on the skin
    • Soter N.A. Acute effects of ultraviolet radiation on the skin. Semin. Dermatol. 9:1990;11-15
    • (1990) Semin. Dermatol. , vol.9 , pp. 11-15
    • Soter, N.A.1
  • 155
    • 0035472919 scopus 로고    scopus 로고
    • Effects of solar radiation on cutaneous detoxification pathways
    • Afaq F., Mukhtar H. Effects of solar radiation on cutaneous detoxification pathways. J. Photochem. Photobiol. B. 63:2001;61-69
    • (2001) J. Photochem. Photobiol. B , vol.63 , pp. 61-69
    • Afaq, F.1    Mukhtar, H.2
  • 156
    • 0026570156 scopus 로고
    • Early molecular events in the induction phase of contact sensitivity
    • Enk A.H., Katz S.I. Early molecular events in the induction phase of contact sensitivity. Proc. Natl. Acad. Sci. U.S.A. 89:1992;1398-1402
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 1398-1402
    • Enk, A.H.1    Katz, S.I.2
  • 158
    • 0025605056 scopus 로고
    • Evidence for an epidermal cytokine network
    • Luger T.A., Schwarz T. Evidence for an epidermal cytokine network. J. Invest. Dermatol. 95:1990;100S-104S
    • (1990) J. Invest. Dermatol. , vol.95
    • Luger, T.A.1    Schwarz, T.2
  • 159
    • 0029664650 scopus 로고    scopus 로고
    • Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms
    • Lee J.C., Young P.R. Role of CSB/p38/RK stress response kinase in LPS and cytokine signaling mechanisms. J. Leukoc. Biol. 59:1996;152-157
    • (1996) J. Leukoc. Biol. , vol.59 , pp. 152-157
    • Lee, J.C.1    Young, P.R.2
  • 160
    • 0029983730 scopus 로고    scopus 로고
    • The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
    • Beyaert R., Cuenda A., Vanden Berghe W., Plaisance S., Lee J.C., Haegeman G., Cohen P., Fiers W. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J. 15:1996;1914-1923
    • (1996) EMBO J. , vol.15 , pp. 1914-1923
    • Beyaert, R.1    Cuenda, A.2    Vanden Berghe, W.3    Plaisance, S.4    Lee, J.C.5    Haegeman, G.6    Cohen, P.7    Fiers, W.8
  • 161
    • 0032488837 scopus 로고    scopus 로고
    • P38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor
    • Vanden Berghe W., Plaisance S., Boone E., De Bosscher K., Schmitz M.L., Fiers W., Haegeman G. p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-kappaB p65 transactivation mediated by tumor necrosis factor. J. Biol. Chem. 273:1998;3285-3290
    • (1998) J. Biol. Chem. , vol.273 , pp. 3285-3290
    • Vanden Berghe, W.1    Plaisance, S.2    Boone, E.3    De Bosscher, K.4    Schmitz, M.L.5    Fiers, W.6    Haegeman, G.7
  • 162
    • 0034673663 scopus 로고    scopus 로고
    • IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes
    • Wery-Zennaro S., Zugaza J.L., Letourneur M., Bertoglio J., Pierre J. IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes. Oncogene. 19:2000;1596-1604
    • (2000) Oncogene , vol.19 , pp. 1596-1604
    • Wery-Zennaro, S.1    Zugaza, J.L.2    Letourneur, M.3    Bertoglio, J.4    Pierre, J.5
  • 163
    • 0026669423 scopus 로고
    • UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: Relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion
    • Cooper K.D., Oberhelman L., Hamilton T.A., Baadsgaard O., Terhune M., LeVee G., Anderson T., Koren H. UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion. Proc. Natl. Acad. Sci. U.S.A. 89:1992;8497-8501
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 8497-8501
    • Cooper, K.D.1    Oberhelman, L.2    Hamilton, T.A.3    Baadsgaard, O.4    Terhune, M.5    Levee, G.6    Anderson, T.7    Koren, H.8
  • 164
    • 0019272188 scopus 로고
    • Cell-mediated immunity in patients with basal and squamous cell skin cancer
    • Weimar V.M., Ceilley R.I., Goeken J.A. Cell-mediated immunity in patients with basal and squamous cell skin cancer. J. Am. Acad. Dermatol. 2:1980;143-147
    • (1980) J. Am. Acad. Dermatol. , vol.2 , pp. 143-147
    • Weimar, V.M.1    Ceilley, R.I.2    Goeken, J.A.3
  • 165
    • 0029860936 scopus 로고    scopus 로고
    • Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors
    • Rosette C., Karin M. Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors. Science. 274:1996;1194-1197
    • (1996) Science , vol.274 , pp. 1194-1197
    • Rosette, C.1    Karin, M.2
  • 166
    • 0027145632 scopus 로고
    • Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family
    • Suda T., Takahashi T., Golstein P., Nagata S. Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell. 75:1993;1169-1178
    • (1993) Cell , vol.75 , pp. 1169-1178
    • Suda, T.1    Takahashi, T.2    Golstein, P.3    Nagata, S.4
  • 167
    • 0028913550 scopus 로고
    • A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain
    • Boldin M.P., Varfolomeev E.E., Pancer Z., Mett I.L., Camonis J.H., Wallach D. A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain. J. Biol. Chem. 270:1995;7795-7798
    • (1995) J. Biol. Chem. , vol.270 , pp. 7795-7798
    • Boldin, M.P.1    Varfolomeev, E.E.2    Pancer, Z.3    Mett, I.L.4    Camonis, J.H.5    Wallach, D.6
  • 168
    • 0029026548 scopus 로고
    • FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis
    • Chinnaiyan A.M., O'Rourke K., Tewari M., Dixit V.M. FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis. Cell. 81:1995;505-512
    • (1995) Cell , vol.81 , pp. 505-512
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Tewari, M.3    Dixit, V.M.4
  • 169
    • 0030011398 scopus 로고    scopus 로고
    • Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
    • Boldin M.P., Goncharov T.M., Goltsev Y.V., Wallach D. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death. Cell. 85:1996;803-815
    • (1996) Cell , vol.85 , pp. 803-815
    • Boldin, M.P.1    Goncharov, T.M.2    Goltsev, Y.V.3    Wallach, D.4
  • 172
    • 0031943921 scopus 로고    scopus 로고
    • Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
    • Aragane Y., Kulms D., Metze D., Wilkes G., Poppelmann B., Luger T.A., Schwarz T. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J. Cell. Biol. 140:1998;171-182
    • (1998) J. Cell. Biol. , vol.140 , pp. 171-182
    • Aragane, Y.1    Kulms, D.2    Metze, D.3    Wilkes, G.4    Poppelmann, B.5    Luger, T.A.6    Schwarz, T.7
  • 175
    • 0033520376 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is involved in Fas ligand expression
    • Hsu S.C., Gavrilin M.A., Tsai M.H., Han J., Lai M.Z. p38 mitogen-activated protein kinase is involved in Fas ligand expression. J. Biol. Chem. 274:1999;25769-25776
    • (1999) J. Biol. Chem. , vol.274 , pp. 25769-25776
    • Hsu, S.C.1    Gavrilin, M.A.2    Tsai, M.H.3    Han, J.4    Lai, M.Z.5
  • 176
    • 0036144679 scopus 로고    scopus 로고
    • Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C
    • Denning M.F., Wang Y., Tibudan S., Alkan S., Nickoloff B.J., Qin J.Z. Caspase activation and disruption of mitochondrial membrane potential during UV radiation-induced apoptosis of human keratinocytes requires activation of protein kinase C. Cell Death Differ. 9:2002;40-52
    • (2002) Cell Death Differ. , vol.9 , pp. 40-52
    • Denning, M.F.1    Wang, Y.2    Tibudan, S.3    Alkan, S.4    Nickoloff, B.J.5    Qin, J.Z.6
  • 177
    • 0033596980 scopus 로고    scopus 로고
    • An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
    • Zou H., Li Y., Liu X., Wang X. An APAF-1 cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. J. Biol. Chem. 274:1999;11549-11556
    • (1999) J. Biol. Chem. , vol.274 , pp. 11549-11556
    • Zou, H.1    Li, Y.2    Liu, X.3    Wang, X.4
  • 181
    • 0037205401 scopus 로고    scopus 로고
    • Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes
    • Sitailo L.A., Tibudan S.S., Denning M.F. Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J. Biol. Chem. 277:2002;19346-19352
    • (2002) J. Biol. Chem. , vol.277 , pp. 19346-19352
    • Sitailo, L.A.1    Tibudan, S.S.2    Denning, M.F.3
  • 182
    • 0032545940 scopus 로고    scopus 로고
    • Human keratin-1 bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation
    • Rodriguez-Villanueva J., Greenhalgh D., Wang X.J., Bundman D., Cho S., Delehedde M., Roop D., McDonnell T.J. Human keratin-1 bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation. Oncogene. 16:1998;853-863
    • (1998) Oncogene , vol.16 , pp. 853-863
    • Rodriguez-Villanueva, J.1    Greenhalgh, D.2    Wang, X.J.3    Bundman, D.4    Cho, S.5    Delehedde, M.6    Roop, D.7    McDonnell, T.J.8
  • 183
    • 0030971756 scopus 로고    scopus 로고
    • Bcl-x expression influences keratinocyte cell survival but not terminal differentiation
    • Pena J.C., Fuchs E., Thompson C.B. Bcl-x expression influences keratinocyte cell survival but not terminal differentiation. Cell Growth Differ. 8:1997;619-629
    • (1997) Cell Growth Differ. , vol.8 , pp. 619-629
    • Pena, J.C.1    Fuchs, E.2    Thompson, C.B.3
  • 184
    • 0035328633 scopus 로고    scopus 로고
    • Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis
    • Rossiter H., Beissert S., Mayer C., Schon M.P., Wienrich B.G., Tschachler E., Kupper T.S. Targeted expression of bcl-2 to murine basal epidermal keratinocytes results in paradoxical retardation of ultraviolet- and chemical-induced tumorigenesis. Cancer Res. 61:2001;3619-3626
    • (2001) Cancer Res. , vol.61 , pp. 3619-3626
    • Rossiter, H.1    Beissert, S.2    Mayer, C.3    Schon, M.P.4    Wienrich, B.G.5    Tschachler, E.6    Kupper, T.S.7
  • 185
    • 0033526938 scopus 로고    scopus 로고
    • Inhibition of Bcl-xL expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuli
    • Taylor J.K., Zhang Q.Q., Monia B.P., Marcusson E.G., Dean N.M. Inhibition of Bcl-xL expression sensitizes normal human keratinocytes and epithelial cells to apoptotic stimuli. Oncogene. 18:1999;4495-4504
    • (1999) Oncogene , vol.18 , pp. 4495-4504
    • Taylor, J.K.1    Zhang, Q.Q.2    Monia, B.P.3    Marcusson, E.G.4    Dean, N.M.5
  • 186
    • 0032921107 scopus 로고    scopus 로고
    • Alterations in cell death and cell cycle progression in the UV-irradiated epidermis of bcl-2-deficient mice
    • Gillardon F., Moll I., Meyer M., Michaelidis T.M. Alterations in cell death and cell cycle progression in the UV-irradiated epidermis of bcl-2-deficient mice. Cell Death Differ. 6:1999;55-60
    • (1999) Cell Death Differ. , vol.6 , pp. 55-60
    • Gillardon, F.1    Moll, I.2    Meyer, M.3    Michaelidis, T.M.4
  • 188


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.