Loss of fas-ligand expression in mouse keratinocytes during UV carcinogenesis

American Journal of Pathology

Volumn 157, Issue 6, 2000, Pages 1975-1981

  Ouhtit, Allal ^a   Gorny, Alexander ^a   Muller, H Konrad ^b   Hill, Laurie L ^a   Owen Schaub, Laurie ^a   Ananthaswamy, Honnavara N ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TASMANIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FAS LIGAND;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL INTERACTION; DNA DAMAGE; GENE DISRUPTION; GENE MUTATION; KERATINOCYTE; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION CARCINOGENESIS; RECEPTOR UPREGULATION; SKIN CANCER; SUNBURN; ULTRAVIOLET RADIATION;

EID: 0033638179     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64836-5     Document Type: Article

References (38)

1. Nonmelanoma skin cancer in the United States: Incidence
2. Incidence of nonmelanoma skin cancer
3. Ultraviolet radiation and skin cancer of humans
4. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma
5. Actinic injury
6. Cumulative effects of ultraviolet radiation on the skin: Cancer and photoaging
7. Immunological effects of ultraviolet radiation
8. UV-induced skin cancer in a hairless mouse model
9. Sunlight and sunburn in human skin cancer. p53, apoptosis, and tumor promotion
10. Sunlight and skin cancer: Inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens
11. High frequency of p53 mutations in ultraviolet radiation-induced murine skin tumors: Evidence for strand bias and tumor heterogeneity
12. Frequent clones of p53-mutated keratinocytes in normal human skin
13. Sunburn and p53 in the onset of skin cancer
14. Wild-type p53 is a cell cycle checkpoint determinant following irradiation
15. Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice
16. Cellular proofreading
17. p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes
18. p53-mediated protective responses to UV irradiation
19. Sunlight and skin cancer
20. Fas ligand: A sensor for DNA damage critical in skin cancer etiology
21. CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells
22. A role for CD95 ligand in preventing graft rejection
23. Fas ligand-induced apoptosis as a mechanism of immune privilege
24. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
25. A critical role for Fas ligand in the active suppression of systemic immune responses by ultraviolet radiation
26. The Fas counter attack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
27. Fas and Fas ligand interactions suppress melanoma lung metastasis
28. Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression
29. Temporal events in skin injury and the early adaptive responses in ultraviolet-irradiated mouse skin
30. Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver
31. Fas-induced apoptosis, and diseases caused by its abnormality
32. p38 mitogen-activated protein kinase is involved in Fas ligand expression
33. Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells
34. DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1
35. Bcl-2-mediated drug resistance: Inhibition of apoptosis by blocking nuclear factor of activated T lymphocytes (NFAT)-induced Fas ligand transcription
36. Fungal metabolite FR901228 inhibits c-Myc and Fas ligand expression
37. Activation-dependent transcriptional regulation of the human Fas promoter requires NF-kappaB p50-p65 recruitment
38. Early p53 alterations in mouse skin carcinogenesis by UVB radiation: Immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells