ΔNp63α functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes

Oncogene

Volumn 22, Issue 23, 2003, Pages 3635-3644

  King, Kathryn E ^a   Ponnamperuma, Roshini M ^a   Yamashita, Toshiharu ^b   Tokino, Takashi ^b   Lee, Lela A ^c   Young, Marian F ^d   Weinberg, Wendy C ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Np63 ; Epidermal differentiation; Keratinocytes; p53 homologues; p63

Indexed keywords

CALCIUM ION; FILAGGRIN; KERATIN 10; PROTEIN; PROTEIN DELTANP63ALPHA; UNCLASSIFIED DRUG; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CALCIUM; CYSTEINE PROTEINASE INHIBITOR; DNA BINDING PROTEIN; ISOPROTEIN; PEPTIDE CHLOROMETHYL KETONE; PHOSPHOPROTEIN; PROTEIN P53; RECOMBINANT PROTEIN; TP73L PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRP63 PROTEIN, MOUSE; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; BASAL CELL; CARCINOGENESIS; CELL ASSAY; CELL DIFFERENTIATION; CELL LEVEL; CELL SURVIVAL; CELL TYPE; DNA RESPONSIVE ELEMENT; EPITHELIUM; EXTRACELLULAR CALCIUM; FIBROBLAST; GENE OVEREXPRESSION; GROWTH DISORDER; HOMEOSTASIS; IN VITRO STUDY; KERATINOCYTE; MORPHOLOGY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; REGULATORY MECHANISM; REPORTER GENE; SQUAMOUS CELL CARCINOMA; TIME; TRANSACTIVATION; TRANSCRIPTION REGULATION; ADENOVIRUS; ANIMAL; ANTIBODY SPECIFICITY; BINDING SITE; BONE TUMOR; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; OSTEOSARCOMA; PATHOLOGY; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

ANIMALIA; MURINAE;

ADENOVIRIDAE; AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BINDING SITES; BONE NEOPLASMS; CALCIUM; CELL DIFFERENTIATION; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; FIBROBLASTS; GENES, REPORTER; GENES, TUMOR SUPPRESSOR; HUMANS; KERATINOCYTES; MICE; MICE, INBRED C57BL; ORGAN SPECIFICITY; OSTEOSARCOMA; PHOSPHOPROTEINS; PROTEIN ISOFORMS; RECOMBINANT PROTEINS; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 0037804687     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206536     Document Type: Article

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