Quantitative detection of ultraviolet-specific p53 mutations in normal skin from Japanese patients

Cancer Epidemiology Biomarkers and Prevention

Volumn 6, Issue 6, 1997, Pages 433-438

  Ouhtit, Allal ^a   Ueda, Masato ^b   Nakazawa, Hisayoshi ^a   Ichihashi, Masamitsu ^b   Dumaz, Nicolas ^c   Sarasin, Alain ^c   Yamasaki, Hiroshi ^a  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b KOBE UNIVERSITY   (Japan)

^c Institut de Recherches Scientifiques sur le Cancer   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER RISK; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; JAPAN; MUTATION RATE; POINT MUTATION; PRIORITY JOURNAL; SKIN BIOPSY; SKIN CANCER; SUNLIGHT; TUMOR SUPPRESSOR GENE; ULTRAVIOLET RADIATION;

ADULT; AGE DISTRIBUTION; AGED; AGED, 80 AND OVER; BIOPSY; DNA, NEOPLASM; GENES, P53; HUMANS; JAPAN; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; REPETITIVE SEQUENCES, NUCLEIC ACID; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

EID: 0031000263     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Yamasaki, H., Galiana, C., and Nakazawa, H. Do genetic alterations found in tumors reflect exposure to carcinogen? In: O. H. Iversen (ed.). Cancer Causation: Exploring New Frontiers, pp. 153-166. Washington, DC: Taylor & Francis, 1993.
2. Mao L., and Sidransky, D. Cancer screening based on genetic alterations in human tumors. Cancer Res. 54: 1939-1940, 1994.
3. Rees J. L. p53 and the origins of skin cancer. J. Invest. Dermatol., 104: 883-884, 1995.
4. Weinberg, R. A. Oncogenes, tumour suppressor genes, and cell transformation: trying to put it all together. In: J. Brugge, T. Curran, E. Harlow, and F. MacCormick (eds.). Origins of Human Cancer, pp. 1-16. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1991.
5. Ziegler, A., Jonason, A. S., Leffell, D. J., Simon, J. A., Sharma, H. W., Kimmelman, J., Remington, L., Jaks, T., and Brash, D. E. Sunburn and p53 in the onset of skin cancer. Nature (Lond.), 372: 773-776, 1994.
6. Hussain, S. P., Aguilar, F., and Cerutti, P. Mutagenesis of codon 248 of the human p53 tumor suppressor gene by N-ethyl-N-nitrosourea. Oncogene, 9: 13-18, 1994.
7. Pourzand, C., and Cerutti, P. Genotypic mutation analysis by RFLP/PCR. Mutat. Res., 288: 113-121, 1993.
8. Ronai, Z., and Yakubovskaya, M. PCR in clinical diagnosis. J. Clin. Lab. Anal, 9: 269-283, 1995.
9. Armstrong, B. K., and Kricker, A. Skin cancer. Dermatol. Clin., 13: 583-594, 1995.
10. Green, A. Changing patterns in incidence of non-melanoma skin cancer. Epithelial Cell Bio]., 1: 47-51, 1992.
11. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Solar and Ultraviolet Radiation, pp. 43-279. Lyon, France: IARC, 1992.
12. Armstrong, B. K. Stratospheric ozone and health. Int. J. Epidemiol., 23: 873-885, 1994.
13. Dumaz, N., Drougard, C., Sarasin, A., and Daya-Grosjean, L. Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA repair-deficient xeroderma pigmentosum patients. Proc. Natl. Acad. Sci. USA, 90: 10529-10533, 1993.
14. Dumaz, N., Stary, A., Soussi, T., Daya-Grosjean, L., and Sarasin, A. Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene. Mutat. Res., 307:375-386, 1994.
15. Kanjilal, S., Strom, S. S., Clayman, G. L., Weber, R. S., El-Naggar, A. K., Kapur, V., Cummings, K. K., Hill, L. A., Spitz, M. R., Kripke, M. L., and Ananthaswamy, H. N. p53 mutations in nonmelanoma skin cancer of the head and neck: molecular evidence for field cancerization. Cancer Res., 55: 3604-3609, 1995.
16. Brash, D. E., Rudolph, J. A., Simon, J. A., Lin, A., MacKenna, G. J., Baden, H. P., Halperin, A. J., and Pontén, J. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad. Sci. USA, 88: 10124-10128, 1991.
17. Rady, P., Scinicariello, F., Wagner, R. F., and Tyring, S. K. p53 mutations in basal cell carcinomas. Cancer Res., 52: 3804-3806, 1992.
18. Tomaletti, S., Rozek, D., and Pfeifer, G. P. The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene, 8: 2051-2057, 1993.
19. Amstad, P., Hussain, S. P., and Cerutti, P. Ultraviolet B light-induced mutagenesis of p53 hot-spot codons 248 and 249 in human skin fibroblasts. Mol. Carcinog., 10: 181-188, 1994.
20. Sage, E. Distribution and repair of photolesions in DNA: genetic consequences and the role of sequence context. Photochem. Photobiol., 57: 163-174, 1993.
21. Nakazawa, H., English, D., Randell, P. L., Nakasawa, K., Martel. N., Armstrong, B. K., and Yamasaki, H. UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement. Proc. Natl. Acad. Sci. USA, 91: 360-364, 1994.
22. Ziegler, A. M., Leffell, D. J., Kunala, S., Sharma. H. W., Gailani, M., Simon, J. A., Halperin, A. J., Baden, H. P., Shapiro, P. E., Bale, A. E., and Brash, D. E. Mutation hot spots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc. Natl. Acad. Sci. USA, 90: 4216-4220, 1993.
23. de Fromentel, C., and Soussi, T. The p53 tumor suppressor gene: a model for investigating human mutagenesis. Genes Chromosomes & Cancer, 4: 1-4, 1992.
24. Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. p53 mutations in human cancers. Science (Washington, DC), 253: 49-53, 1991.
25. Pierceall, W. E., Mukhopadhyay, T., Goldberg, L. H., and Ananthaswamy, H. N. Mutations in the p53 tumor suppressor gene in human cutaneous squamous cell carcinomas. Mol. Carcinog., 4: 445-449, 1991.
26. Sato M., Nishigori, C., Zghal, M., Yagi, T., and Takebe, H. UV-specific mutations in p53 gene in skin tumors in XP patients. Cancer Res., 53: 2944-2946, 1993.
27. Gelfand, D. H., and While, T. J. Thermostable DNA Polymerases in PCR Protocols: A Guide to Methods and Applications, p. 129. New York: Academic Press, 1990.
28. Berg, R. J. W., Van Kranen, H. J., Rebel, H. G., De Vries, A., Van Vloten, W. A., Van Kreijel, C. F., Van der Leun, J. C., and Gruijl, F. R. Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells. Proc. Natl. Acad. Sci. USA, 93: 274-278, 1996.
29. Ren, Z-P., Hedrum, A., Pontén, F., Nistér, M., Ahmadian, A., Lundeberg, J., Uhlén, M., and Pontén, J. Human epidermal cancer and accompanying precursors have identical p53 mutations different from mutations in adjacent areas of clonally expanded non-neoplastic keratinocytes. Oncogene, 12: 765-773, 1996.
30. Sage, E., Lamolet, B., Brulay, E., Moustacchi, E., Chateauneuf, A., and Drobetsky, A. Mutagenic specificity of solar UV light in nucleotide excision repair-deficient rodent cells. Proc. Natl. Acad. Sci. USA, 93: 176-180, 1996.
31. Tornaletti, S., and Pfeifer, G. P. Slow repair of pyrimidine dimers at p53 mutation hot spots in skin cancer. Science (Washington, DC), 263: 1436-1438, 1994.
32. Chuang, T. Y., Reizneir, G. T., Elpern, D. J., Stone, J. L., and Farmer, E. R. Nonmelanoma skin cancer in Japanese ethnic Hawaiians in Kauai, Hawaii: an incidence report. J. Am. Acad. Dermatol., 33: 422-426, 1995.
33. Jonason, A. S., Kunala, S., Price, G. J., Restifo, R. J., Spinelli, H. M., Persing, J. A., Leffell, D. J., Tarone, R. E., and Brash, D. E. Frequent clones of p53mutated keratinocytes in normal human skin. Proc. Natl. Acad. Sci. USA, 93: 14025-14029, 1996.
34. Green, A. C. Premature ageing of the skin in a Queensland population. Med. J. Aust., 155: 473-474, 1991.
35. Urano, Y., Asano, T., Yoshimoto, K., Iwahana, H., Kubo, Y., Kalo, S., Sasaki, S., Takeuchi, N., Uchida, N., Nakanishi, H., Arase, S., and Itakura, M. Frequent p53 accumulation in the chronically sun-exposed epidermis and clonal expansion of p53 mutant cells in the epidermis adjacent to basal cell carcinoma. J. Invest. Dermatol., 104: 928-932, 1995.
36. Reid, T., and Loch, L. Mutagenic specificity of oxygen radicals produced by human leukemic cells. Cancer Res., 52: 1052-1086, 1992.
37. Reid, T., and Loeb, L. Tandem double CC to TT mutations are produced by reactive oxygen species. Proc. Natl. Acad. Sci. USA, 90: 3904-3907, 1993.