메뉴 건너뛰기




Volumn 6, Issue 2, 2004, Pages 89-102

Cancer gene suppression strategies: Issues and potential

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOZYME; ANTINEOPLASTIC AGENT; ANTISENSE OLIGONUCLEOTIDE; ANTIVIRUS AGENT; BCR ABL PROTEIN; DACARBAZINE; DEOXYRIBOZYME; DOUBLE STRANDED RNA; EPIDERMAL GROWTH FACTOR RECEPTOR; GELATINASE B; GLYCOPROTEIN P; HERZYME; IMATINIB; ISIS 3521; LIPOSOME; MULTIDRUG RESISTANCE PROTEIN 1; MYC PROTEIN; NUCLEIC ACID; OBLIMERSEN; ONCOPROTEIN; PROTEIN BCL 2; PROTEIN KINASE C ALPHA; PROTEIN MDM2; PROTEIN P53; RAS PROTEIN; RIBOZYME; RNA; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN; VIRUS VECTOR;

EID: 1942531959     PISSN: 14673037     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (6)

References (124)
  • 1
    • 0035502598 scopus 로고    scopus 로고
    • Antisense and/or immunostimulatory oligonucleotide therapeutics
    • Agrawal, S., and Kandimalla, E.R. 2001. Antisense and/ or immunostimulatory oligonucleotide therapeutics. Curr. Cancer Drug Targets. 1:197-209.
    • (2001) Curr. Cancer Drug Targets , vol.1 , pp. 197-209
    • Agrawal, S.1    Kandimalla, E.R.2
  • 2
    • 0034012647 scopus 로고    scopus 로고
    • Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates
    • Astriab-Fisher, A., Sergueev, D.S., Fisher, M., Shaw, B.R., and Juliano, R.L. 2000. Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochem. Pharmacol. 60: 83-90.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 83-90
    • Astriab-Fisher, A.1    Sergueev, D.S.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 3
    • 0036844766 scopus 로고    scopus 로고
    • In vivo characteristics of cationic liposomes as delivery vectors for gene therapy
    • Audouy, S.A.L., de Leij, L.F.M.H., Hoekstra, D., and Molema, G. 2002. In vivo characteristics of cationic liposomes as delivery vectors for gene therapy. Pharm. Res. 19:1599-1605.
    • (2002) Pharm. Res. , vol.19 , pp. 1599-1605
    • Audouy, S.A.L.1    de Leij, L.F.M.H.2    Hoekstra, D.3    Molema, G.4
  • 4
    • 0001388461 scopus 로고    scopus 로고
    • Adenoviral gene therapy for cancer: From vectors to targeted and replication competent agents
    • Bauerschmitz, G.J., Barker, S.D., and Hemminki, A. 2002. Adenoviral gene therapy for cancer: from vectors to targeted and replication competent agents. Int. J. Oncol. 21:1161-1174.
    • (2002) Int. J. Oncol. , vol.21 , pp. 1161-1174
    • Bauerschmitz, G.J.1    Barker, S.D.2    Hemminki, A.3
  • 5
    • 0031788404 scopus 로고    scopus 로고
    • Designing ribozymes for the inhibition of gene expresion
    • Bramlage, B., Luzi, E., and Eckstein, F. 1998. Designing ribozymes for the inhibition of gene expresion. Trends in Biotech. 16: 434-438.
    • (1998) Trends in Biotech. , vol.16 , pp. 434-438
    • Bramlage, B.1    Luzi, E.2    Eckstein, F.3
  • 6
    • 0025838699 scopus 로고
    • Efficient trans cleavage and a common structural motif for the ribozymes of the human hepatitis δ agent
    • Branch, A.D., and Robertson, J.D. 1991. Efficient trans cleavage and a common structural motif for the ribozymes of the human hepatitis δ agent. Proc. Natl. Acad. Sci. USA. 88: 10163-10167.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10163-10167
    • Branch, A.D.1    Robertson, J.D.2
  • 7
    • 0035965501 scopus 로고    scopus 로고
    • Gene delivery with synthetic (non viral) carriers
    • Brown, M.D., Schatzlein, A.G., and Uchegbu, I.F. 2001. Gene delivery with synthetic (non viral) carriers. Int. J. Pharm. 229: 1-21.
    • (2001) Int. J. Pharm. , vol.229 , pp. 1-21
    • Brown, M.D.1    Schatzlein, A.G.2    Uchegbu, I.F.3
  • 8
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp, T.R., Bernards, R., and Agami, R. 2002a. A system for stable expression of short interfering RNAs in mammalian cells. Science. 296: 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 9
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp, T.R., Bernards, R., and Agami, R. 2002b. Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell. 2:243-247.
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 10
    • 0035525965 scopus 로고    scopus 로고
    • Introduction to retroviruses and retroviral vectors
    • Buchschacher, G.L. Jr. 2001. Introduction to retroviruses and retroviral vectors. Somat. Cell Mol. Genet. 26:1-11.
    • (2001) Somat. Cell Mol. Genet. , vol.26 , pp. 1-11
    • Buchschacher Jr., G.L.1
  • 11
    • 0023055382 scopus 로고
    • Nucleotide sequence and newly formed phophodiester bond of spontaneously limaged satellite tobacco ringspot virus RNA
    • Buzayan, J.M., Hampel, A., and Bruening, F. 1986. Nucleotide sequence and newly formed phophodiester bond of spontaneously limaged satellite tobacco ringspot virus RNA. Nucleic Acids Res. 14: 9729-9743.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 9729-9743
    • Buzayan, J.M.1    Hampel, A.2    Bruening, F.3
  • 12
    • 0029364471 scopus 로고
    • Suppression of lung cancer cell growth by ribozyme-mediated modification of p53 pre-mRNA
    • Cai, D.W., Mukhopadhyay, T., and Roth, J.A. 1995. Suppression of lung cancer cell growth by ribozyme-mediated modification of p53 pre-mRNA. Cancer Gene Ther. 2:199-205.
    • (1995) Cancer Gene Ther. , vol.2 , pp. 199-205
    • Cai, D.W.1    Mukhopadhyay, T.2    Roth, J.A.3
  • 13
    • 0036001055 scopus 로고    scopus 로고
    • Catalytic DNA: A novel tool for gene suppression
    • Cairns, M.J., Saravolac, E.G., and Sun L.Q. 2002. Catalytic DNA: a novel tool for gene suppression. Curr. Drug Targets. 3:269-279.
    • (2002) Curr. Drug Targets , vol.3 , pp. 269-279
    • Cairns, M.J.1    Saravolac, E.G.2    Sun, L.Q.3
  • 14
    • 0028284281 scopus 로고
    • Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells
    • Campos, L., Sabido, O., Rouault, J.P., and Guyotat, D. 1994. Effects of BCL-2 antisense oligodeoxynucleotides on in vitro proliferation and survival of normal marrow progenitors and leukemic cells. Blood. 84:595-600.
    • (1994) Blood , vol.84 , pp. 595-600
    • Campos, L.1    Sabido, O.2    Rouault, J.P.3    Guyotat, D.4
  • 15
    • 0035859929 scopus 로고    scopus 로고
    • Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
    • Caplen, N.J., Parrish, S., Imani, F., Fire, A., and Morgan, R.A. 2001. Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc. Natl. Acad. Sci. USA. 98:9742-9747.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 9742-9747
    • Caplen, N.J.1    Parrish, S.2    Imani, F.3    Fire, A.4    Morgan, R.A.5
  • 16
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet, P., and Jain, R.K. 2000. Angiogenesis in cancer and other diseases. Nature. 407: 249-257.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 18
    • 0019856947 scopus 로고
    • In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
    • Cech, T.R., Zaug, A. J. and Grobowzski, P.J. 1981. In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell. 27:487-496.
    • (1981) Cell , vol.27 , pp. 487-496
    • Cech, T.R.1    Zaug, A.J.2    Grobowzski, P.J.3
  • 20
    • 20244380289 scopus 로고    scopus 로고
    • A safety and pharmacokinetic study of a mixed-backbone oligonucleotide (GEM231) targeting the type I protein kinase A by two-hour infusions in patients with refractory solid tumors
    • Chen, H.X., Marshall, J.L., Ness, E., Martin, R.R., Dvorchik, B., Rizvi, N., Marquis, J., McKinlay, M., Dahut, W. and Hawkins, M.J., 2000. A safety and pharmacokinetic study of a mixed-backbone oligonucleotide (GEM231) targeting the type I protein kinase A by two-hour infusions in patients with refractory solid tumors. Clin. Cancer Res. 6:1259-1266.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1259-1266
    • Chen, H.X.1    Marshall, J.L.2    Ness, E.3    Martin, R.R.4    Dvorchik, B.5    Rizvi, N.6    Marquis, J.7    McKinlay, M.8    Dahut, W.9    Hawkins, M.J.10
  • 21
    • 0029782859 scopus 로고    scopus 로고
    • Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
    • Cheng, S.Y., Huang, H.J., Nagane, M., Ji, X.D., Wang, D., Shih, C.C., Arap, W., Huang, C.M., and Cavenee, W.K. 1996. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc. Natl. Acad. Sci. USA 93:8502-8507.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8502-8507
    • Cheng, S.Y.1    Huang, H.J.2    Nagane, M.3    Ji, X.D.4    Wang, D.5    Shih, C.C.6    Arap, W.7    Huang, C.M.8    Cavenee, W.K.9
  • 22
    • 0037329372 scopus 로고    scopus 로고
    • RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines
    • 2003
    • Cioca, D.P., Aoki, Y., and Kiyosawa, K. 2003. RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines. Cancer Gene Ther. 2003 10:125-133.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 125-133
    • Cioca, D.P.1    Aoki, Y.2    Kiyosawa, K.3
  • 23
    • 0034783583 scopus 로고    scopus 로고
    • Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer
    • European Organization for Research and Treatment of Cancer (EORTC) and Fumoleau, P. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group Report
    • Coudert, B., Anthoney, A., Fiedler, W., Droz, J.P., Dieras, V., Borner, M., Smyth, J.F., Morant, R., de Vries, M.J., Roelvink, M., European Organization for Research and Treatment of Cancer (EORTC) and Fumoleau, P. 2001. Phase II trial with ISIS 5132 in patients with small-cell (SCLC) and non-small cell (NSCLC) lung cancer. A European Organization for Research and Treatment of Cancer (EORTC) Early Clinical Studies Group Report. Eur. J. Cancer 37:2194-2198.
    • (2001) Eur. J. Cancer , vol.37 , pp. 2194-2198
    • Coudert, B.1    Anthoney, A.2    Fiedler, W.3    Droz, J.P.4    Dieras, V.5    Borner, M.6    Smyth, J.F.7    Morant, R.8    de Vries, M.J.9    Roelvink, M.10
  • 24
    • 0037148329 scopus 로고    scopus 로고
    • Telomerase inhibition, oligonucleotides, and clinical trials
    • Corey, D.R. 2002. Telomerase inhibition, oligonucleotides, and clinical trials. Oncogene. 21:631-637.
    • (2002) Oncogene , vol.21 , pp. 631-637
    • Corey, D.R.1
  • 25
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory, S., and Adams, J.M. 2002. The Bcl2 family: regulators of the cellular life-or-death switch. Nat. Rev. Cancer. 2: 647-656.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 26
    • 0032700656 scopus 로고    scopus 로고
    • Molecular mechanisms of action of antisense drugs
    • Crooke, S.T., 1999. Molecular mechanisms of action of antisense drugs. Biochim. Biophys. Acta. 1489:31-44.
    • (1999) Biochim. Biophys. Acta , vol.1489 , pp. 31-44
    • Crooke, S.T.1
  • 27
    • 0003325879 scopus 로고    scopus 로고
    • Multicenter phase II trial of an antisense inhibitor of H-ras (ISIS-2503) in advanced non-small cell lung cancer (NSCLC)
    • Dang, T., Johnson, D., Kelly, K., Rizvi, N., Holmlund, J. and Dorr, A. 2001. Multicenter phase II trial of an antisense inhibitor of H-ras (ISIS-2503) in advanced non-small cell lung cancer (NSCLC). Proc. Am. Soc. Clin. Oncol. 20: 332a.
    • (2001) Proc. Am. Soc. Clin. Oncol. , vol.20
    • Dang, T.1    Johnson, D.2    Kelly, K.3    Rizvi, N.4    Holmlund, J.5    Dorr, A.6
  • 28
    • 0036229451 scopus 로고    scopus 로고
    • Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo
    • Dass, C.R. 2002. Cytotoxicity issues pertinent to lipoplex-mediated gene therapy in-vivo. J. Pharm. Pharmacol. 54:593-601.
    • (2002) J. Pharm. Pharmacol. , vol.54 , pp. 593-601
    • Dass, C.R.1
  • 31
    • 0030229774 scopus 로고    scopus 로고
    • Ribozyme-mediated suppression of v-myc expression abrogates apoptosis in transformed monocytes
    • Dolnikov, A., King, A., Luxford, C., Symonds, G., and Sun, L.Q. 1996. Ribozyme-mediated suppression of v-myc expression abrogates apoptosis in transformed monocytes. Cancer Gene Ther. 3:289-295.
    • (1996) Cancer Gene Ther. , vol.3 , pp. 289-295
    • Dolnikov, A.1    King, A.2    Luxford, C.3    Symonds, G.4    Sun, L.Q.5
  • 32
    • 0033623635 scopus 로고    scopus 로고
    • Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation
    • Dolnikov, A., Millington, M., Sun, L-Q., and Symonds, G. 2000. Induced p21WAF1 expression acts to reverse myc myelomonocytic cell transformation. Cancer Gene Ther. 7:1491-1503.
    • (2000) Cancer Gene Ther. , vol.7 , pp. 1491-1503
    • Dolnikov, A.1    Millington, M.2    Sun, L.-Q.3    Symonds, G.4
  • 33
    • 0141919611 scopus 로고    scopus 로고
    • A sensitive dual fluorescence reporter system enables positive selection of ras suppressors by suppression of ras-induced apoptosis
    • In Press
    • Dolnikov, A., Shen, S., Millington, M., Passioura, T., Pedler, M., Rasko, J.E.J., and Symonds, G. 2003. A sensitive dual fluorescence reporter system enables positive selection of ras suppressors by suppression of ras-induced apoptosis. Cancer Gene Ther. In Press.
    • (2003) Cancer Gene Ther.
    • Dolnikov, A.1    Shen, S.2    Millington, M.3    Passioura, T.4    Pedler, M.5    Rasko, J.E.J.6    Symonds, G.7
  • 35
    • 0035810142 scopus 로고    scopus 로고
    • Activity of a specific inhibitor of the bcr-abl tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome
    • Druker, B.J., Sawyers, C.L., Kantarjian, H., Resta, D.J., Reese, S.F., Ford, J.M., Capdeville, R., and Talpaz, M. 2001b. Activity of a specific inhibitor of the bcr-abl tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome. N. Engl. J. Med. 344:1038-1042.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1038-1042
    • Druker, B.J.1    Sawyers, C.L.2    Kantarjian, H.3    Resta, D.J.4    Reese, S.F.5    Ford, J.M.6    Capdeville, R.7    Talpaz, M.8
  • 37
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • Elbashir, S.M., Harborth, J., Lendeckel, W., Yalcin, A., Weber, K., and Tuschl, T. 2001. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 38
    • 0036351317 scopus 로고    scopus 로고
    • Analysis of gene function in somatic mammalian cells using small interfering RNAs
    • Elbashir, S.M., Harborth, J., Weber, K., and Tuschl, T. 2002. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods. 26:199-213.
    • (2002) Methods , vol.26 , pp. 199-213
    • Elbashir, S.M.1    Harborth, J.2    Weber, K.3    Tuschl, T.4
  • 39
    • 0023663396 scopus 로고
    • Self-cleavage of plus and minus RNAs of a virusoid and structural model for the active sites
    • Forster, A.C., and Symons, R.H. 1987. Self-cleavage of plus and minus RNAs of a virusoid and structural model for the active sites. Cell. 49:211-220.
    • (1987) Cell , vol.49 , pp. 211-220
    • Forster, A.C.1    Symons, R.H.2
  • 40
    • 0035800507 scopus 로고    scopus 로고
    • Clinical resistance to STI-571 cancer therapy caused by bcr-abl gene mutation or amplification
    • Gorre, M.E., Mohammad, M., Ellwood, K., Hsu, N., Paquette, R., Rao, P.N., and Sawyers, C.L. 2001. Clinical resistance to STI-571 cancer therapy caused by bcr-abl gene mutation or amplification. Science. 293:876-880.
    • (2001) Science , vol.293 , pp. 876-880
    • Gorre, M.E.1    Mohammad, M.2    Ellwood, K.3    Hsu, N.4    Paquette, R.5    Rao, P.N.6    Sawyers, C.L.7
  • 41
    • 0037130565 scopus 로고    scopus 로고
    • Chitosan and its derivatives - A promising non-viral vector for gene transfection
    • Guang Liu, W., and De Yao, K. 2002. Chitosan and its derivatives - a promising non-viral vector for gene transfection. J. Control Release. 83: 1-11.
    • (2002) J. Control Release , vol.83 , pp. 1-11
    • Guang Liu, W.1    De Yao, K.2
  • 42
    • 0021013526 scopus 로고
    • The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
    • Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N., and Altman, S. 1983. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell. 35:849-857.
    • (1983) Cell , vol.35 , pp. 849-857
    • Guerrier-Takada, C.1    Gardiner, K.2    Marsh, T.3    Pace, N.4    Altman, S.5
  • 43
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D., and Weinberg, R.A. 2000. The hallmarks of cancer. Cell. 100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 44
    • 0024291288 scopus 로고
    • Simple RNA enzymes with new and highly specific endoribonuclease activities
    • Haseloff, J., and Gerlach, W.L. 1988. Simple RNA enzymes with new and highly specific endoribonuclease activities. Nature. 334:585-591.
    • (1988) Nature , vol.334 , pp. 585-591
    • Haseloff, J.1    Gerlach, W.L.2
  • 45
    • 0029824947 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system
    • Hua, J., and Muschel, R.J. 1996. Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system. Cancer Res. 56:5279-5284.
    • (1996) Cancer Res. , vol.56 , pp. 5279-5284
    • Hua, J.1    Muschel, R.J.2
  • 46
    • 0023047510 scopus 로고
    • Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid
    • Hutchins, C.J., Rathjen, P.D., Forster, A.C., and Symons, R.H. 1986. Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid. Nucleic Acids Res. 14:3627-3640.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 3627-3640
    • Hutchins, C.J.1    Rathjen, P.D.2    Forster, A.C.3    Symons, R.H.4
  • 50
    • 0030668865 scopus 로고    scopus 로고
    • HER-2/neu is rate-limiting for ovarian cancer growth. Conditional depletion of HER-2/neu by ribozyme targeting
    • Juhl, H., Downing, S.G., Wellstein, A., and Czubayko, F. 1997. HER-2/neu is rate-limiting for ovarian cancer growth. Conditional depletion of HER-2/neu by ribozyme targeting. J. Biol. Chem. 272:29482-29486.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29482-29486
    • Juhl, H.1    Downing, S.G.2    Wellstein, A.3    Czubayko, F.4
  • 51
    • 0033709117 scopus 로고    scopus 로고
    • Catalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biological function
    • Kachigian, L.M. 2000. Catalytic DNAs as potential therapeutic agents and sequence-specific molecular tools to dissect biological function. J. Clin. Investigation. 106:1189-1195.
    • (2000) J. Clin. Investigation , vol.106 , pp. 1189-1195
    • Kachigian, L.M.1
  • 55
    • 0033992633 scopus 로고    scopus 로고
    • Biochemical and clinical implications of the ErbB/ HER signaling network of growth factor receptors
    • Klapper, L.N., Kirschbaum, M.H., Sela, M. and Yarden, Y. 2000. Biochemical and clinical implications of the ErbB/ HER signaling network of growth factor receptors. Adv. Cancer Res. 77:25-79.
    • (2000) Adv. Cancer Res. , vol.77 , pp. 25-79
    • Klapper, L.N.1    Kirschbaum, M.H.2    Sela, M.3    Yarden, Y.4
  • 56
    • 0034083410 scopus 로고    scopus 로고
    • Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide
    • Klasa, R.J., Bally, M.B., Ng, R., Goldie, J.H., Gascoyne, R.D., and Wong, F.M. 2000. Eradication of human non-Hodgkin's lymphoma in SCID mice by BCL-2 antisense oligonucleotides combined with low-dose cyclophosphamide. Clin. Cancer Res. 6:2492-2500.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 2492-2500
    • Klasa, R.J.1    Bally, M.B.2    Ng, R.3    Goldie, J.H.4    Gascoyne, R.D.5    Wong, F.M.6
  • 57
    • 0034660068 scopus 로고    scopus 로고
    • Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins
    • Konopleva, M., Tari, A.M., Estrov, Z., Harris, D., Xie, Z., Zhao, S., Lopez-Berestein, G., and Andreeff, M. 2000. Liposomal Bcl-2 antisense oligonucleotides enhance proliferation, sensitize acute myeloid leukemia to cytosine-arabinoside, and induce apoptosis independent of other antiapoptotic proteins. Blood. 95:3929-3938.
    • (2000) Blood. , vol.95 , pp. 3929-3938
    • Konopleva, M.1    Tari, A.M.2    Estrov, Z.3    Harris, D.4    Xie, Z.5    Zhao, S.6    Lopez-Berestein, G.7    Andreeff, M.8
  • 58
    • 0347904503 scopus 로고    scopus 로고
    • Inhibition of telomerase activity in human cancer cells by RNA interference
    • Kosciolek, B.A., Kalantidis, K., Tabler, M., and Rowley, P.T. 2003. Inhibition of telomerase activity in human cancer cells by RNA interference. Mol. Cancer Ther. 2: 209-216.
    • (2003) Mol. Cancer Ther. , vol.2 , pp. 209-216
    • Kosciolek, B.A.1    Kalantidis, K.2    Tabler, M.3    Rowley, P.T.4
  • 59
    • 0020417286 scopus 로고
    • Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
    • Kruger, K., Grabowski, P.J., Zaug, A.J., Sands, J., Gottschling, D.E., and Cech, T.R. 1982. Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell.31:147-157.
    • (1982) Cell , vol.31 , pp. 147-157
    • Kruger, K.1    Grabowski, P.J.2    Zaug, A.J.3    Sands, J.4    Gottschling, D.E.5    Cech, T.R.6
  • 60
    • 0029119820 scopus 로고
    • Artificial evolution and natural ribozymes
    • Kumar, P.K.R., and Ellington, A.D. 1995. Artificial evolution and natural ribozymes. FASEB J. 9:1183-1195.
    • (1995) FASEB J. , vol.9 , pp. 1183-1195
    • Kumar, P.K.R.1    Ellington, A.D.2
  • 61
    • 0036311178 scopus 로고    scopus 로고
    • Gene silencing in mammalian cells by preformed small RNA duplexes
    • Leirdal, M., and Sioud, M. 2002. Gene silencing in mammalian cells by preformed small RNA duplexes. Biochem. Biophys. Res. Commun. 295:744-748.
    • (2002) Biochem. Biophys. Res. Commun. , vol.295 , pp. 744-748
    • Leirdal, M.1    Sioud, M.2
  • 62
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis, D.L., Hagstrom, J.E., Loomis, A.G., Wolff, J.A., and Herweijer, H. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 2002 32:107-108.
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 63
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis, D.L., Hagstrom, J.E., Loomis, A.G., Wolff, J.A., and Werweijer, H. 2002. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 32:107-108.
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Werweijer, H.5
  • 65
    • 0242455819 scopus 로고    scopus 로고
    • Randomized phase III trial of chemotherapy and antisense oligonucleotide LY900003 (ISIS 3521) in patients with advanced NSCLC: Initial report
    • Lynch, T.J., Raju, R., Lind, M., Riviere, A., Gatzemeier, U., Drorr, A., Holmlund, J., Yuen, A., and Sikic, B. 2003. Randomized phase III trial of chemotherapy and antisense oligonucleotide LY900003 (ISIS 3521) in patients with advanced NSCLC: Initial report. Proc. Am. Soc. Clin. Oncol. 22:623.
    • (2003) Proc. Am. Soc. Clin. Oncol. , vol.22 , pp. 623
    • Lynch, T.J.1    Raju, R.2    Lind, M.3    Riviere, A.4    Gatzemeier, U.5    Drorr, A.6    Holmlund, J.7    Yuen, A.8    Sikic, B.9
  • 68
    • 0028876993 scopus 로고
    • Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21)
    • Matsushita, H., Kobayashi, H., Mori, S., Kizaki, M., and Ikeda, Y. 1995. Ribozymes cleave the AML1/MTG8 fusion transcript and inhibit proliferation of leukemic cells with t(8;21). Biochem Biophys Res Commun. 215:431-437.
    • (1995) Biochem. Biophys. Res. Commun. , vol.215 , pp. 431-437
    • Matsushita, H.1    Kobayashi, H.2    Mori, S.3    Kizaki, M.4    Ikeda, Y.5
  • 70
    • 0032692170 scopus 로고    scopus 로고
    • RNA-polymerase III-driven expression cassettes in human gene therapy
    • Medina, M.F., and Joshi, S. 1999. RNA-polymerase III-driven expression cassettes in human gene therapy. Curr. Opin. Mol. Ther. 1:580-594.
    • (1999) Curr. Opin. Mol. Ther. , vol.1 , pp. 580-594
    • Medina, M.F.1    Joshi, S.2
  • 71
    • 0343314893 scopus 로고    scopus 로고
    • Colony formation of soft tissue sarcoma cells is inhibited by lipid-mediated antisense oligodeoxynucleotides targeting the human mdm2 oncogene
    • Meye, A., Wurl, P., Bache, M., Bartel, F., Grunbaum, U., Mansa-ard, J., Schmidt, H., and Taubert, H. 2000. Colony formation of soft tissue sarcoma cells is inhibited by lipid-mediated antisense oligodeoxynucleotides targeting the human mdm2 oncogene. Cancer Lett. 149:181-188.
    • (2000) Cancer Lett. , vol.149 , pp. 181-188
    • Meye, A.1    Wurl, P.2    Bache, M.3    Bartel, F.4    Grunbaum, U.5    Mansa-ard, J.6    Schmidt, H.7    Taubert, H.8
  • 72
    • 0036467391 scopus 로고    scopus 로고
    • The p53 and Mdm2 families in cancer
    • Michael, D., and Oren, M. 2002. The p53 and Mdm2 families in cancer. Curr. Opin. Genet. Dev. 12:53-59.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 53-59
    • Michael, D.1    Oren, M.2
  • 73
    • 0029977448 scopus 로고    scopus 로고
    • Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase
    • Monia, B.P., Johnston, J.F., Geiger, T., Muller, M. and Fabbro, D. 1996. Antitumor activity of a phosphorothioate antisense oligodeoxynucleotide targeted against C-raf kinase. Nat. Med. 2:668-675.
    • (1996) Nat. Med. , vol.2 , pp. 668-675
    • Monia, B.P.1    Johnston, J.F.2    Geiger, T.3    Muller, M.4    Fabbro, D.5
  • 74
    • 0037446068 scopus 로고    scopus 로고
    • Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells
    • Nagy, P., Arndt-Jovin, D.J., and Jovin, T.M. 2003. Small interfering RNAs suppress the expression of endogenous and GFP-fused epidermal growth factor receptor (erbB1) and induce apoptosis in erbB1-overexpressing cells. Exp. Cell Res. 285:39-49.
    • (2003) Exp. Cell Res. , vol.285 , pp. 39-49
    • Nagy, P.1    Arndt-Jovin, D.J.2    Jovin, T.M.3
  • 75
    • 0032148358 scopus 로고    scopus 로고
    • Targeting of PML/ RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells
    • Nason-Burchenal, K., Allopenna, J., Begue, A., Stehelin, D., Dmitrovsky, E., and Martin, P. 1998. Targeting of PML/ RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells. Blood. 92:1758-1767.
    • (1998) Blood , vol.92 , pp. 1758-1767
    • Nason-Burchenal, K.1    Allopenna, J.2    Begue, A.3    Stehelin, D.4    Dmitrovsky, E.5    Martin, P.6
  • 77
    • 0031608678 scopus 로고    scopus 로고
    • p53 tumour suppressor gene therapy for cancer
    • Nielsen L.L., and Maneval, D.C. 1998. p53 tumour suppressor gene therapy for cancer. Cancer Gene Ther. 5:52-63.
    • (1998) Cancer Gene Ther. , vol.5 , pp. 52-63
    • Nielsen, L.L.1    Maneval, D.C.2
  • 78
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison, P.J., Caudy, A.A., Bernstein, E., Hannon, G.J., and Conklin D.S. 2002. Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev. 16:948-958.
    • (2002) Genes Dev. , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 79
    • 0036653097 scopus 로고    scopus 로고
    • RNA interference: The new somatic cell genetics?
    • Paddison, P.J., and Hannon, G.J. 2002. RNA interference: the new somatic cell genetics?. Cancer Cell. 2:17-23.
    • (2002) Cancer Cell , vol.2 , pp. 17-23
    • Paddison, P.J.1    Hannon, G.J.2
  • 83
    • 0038540242 scopus 로고    scopus 로고
    • Antisense therapeutics: From theory to clinical practice
    • Pirollo, K.F., Rait, A., Sleer, L.S., and Chang, E.H. 2003. Antisense therapeutics: from theory to clinical practice. Pharmacol. Ther. 99:55-77.
    • (2003) Pharmacol. Ther. , vol.99 , pp. 55-77
    • Pirollo, K.F.1    Rait, A.2    Sleer, L.S.3    Chang, E.H.4
  • 84
    • 0036968555 scopus 로고    scopus 로고
    • Lentiviral vectors for gene delivery into cells
    • Quinonez, R., and Sutton R.E. 2002. Lentiviral vectors for gene delivery into cells. DNA Cell Biol. 21:937-951.
    • (2002) DNA Cell Biol. , vol.21 , pp. 937-951
    • Quinonez, R.1    Sutton, R.E.2
  • 85
    • 0001183658 scopus 로고    scopus 로고
    • Sensitization of breast cancer cells to taxol by antisense HER-2 oligonucleotides
    • Rait, A., Krygier, J.E., Pirollo, K.F. and Chang, E.H. 1999. Sensitization of breast cancer cells to taxol by antisense HER-2 oligonucleotides. Antisense Nucleic Acid Drug Dev. 9:403-408.
    • (1999) Antisense Nucleic Acid Drug Dev. , vol.9 , pp. 403-408
    • Rait, A.1    Krygier, J.E.2    Pirollo, K.F.3    Chang, E.H.4
  • 87
    • 0041808932 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Adenoviral vectors
    • St George, J.A. 2003. Gene therapy progress and prospects: adenoviral vectors. Gene Ther. 10:1135-1141.
    • (2003) Gene. Ther. , vol.10 , pp. 1135-1141
    • St George, J.A.1
  • 88
    • 0141480922 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in ewing sarcoma cells
    • In Press
    • Sanceau, J., Truchet, S., and Bauvois, B. 2003. Matrix metalloproteinase-9 silencing by RNA interference triggers the migratory-adhesive switch in ewing sarcoma cells. J. Biol. Chem. In Press.
    • (2003) J. Biol. Chem.
    • Sanceau, J.1    Truchet, S.2    Bauvois, B.3
  • 91
  • 92
    • 0028110360 scopus 로고
    • Ribozyme-mediated reversal of the multidrug-resistant phenotype
    • Scanlon, K.J., Ishida, H., and Kashani-Sabet, M. 1994. Ribozyme-mediated reversal of the multidrug-resistant phenotype. Proc. Natl. Acad. Sci. USA. 91:11123-7.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 11123-11127
    • Scanlon, K.J.1    Ishida, H.2    Kashani-Sabet, M.3
  • 93
    • 0030920066 scopus 로고    scopus 로고
    • Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo
    • Scherr, M., Grez, M., Ganser, A., and Engels, J.W. 1997. Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo. J. Biol. Chem. 272:14304-14313.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14304-14313
    • Scherr, M.1    Grez, M.2    Ganser, A.3    Engels, J.W.4
  • 94
    • 0031693324 scopus 로고    scopus 로고
    • Effective reversal of a transformed phenotype by retrovirus-mediated transfer of a ribozyme directed against mutant N-ras
    • Scherr, M., Maurer, A.B., Klein, S., Ganser, A., Engels, J.W., and Grez, M. 1998. Effective reversal of a transformed phenotype by retrovirus-mediated transfer of a ribozyme directed against mutant N-ras. Gene Therapy. 5:1227-1234.
    • (1998) Gene Therapy , vol.5 , pp. 1227-1234
    • Scherr, M.1    Maurer, A.B.2    Klein, S.3    Ganser, A.4    Engels, J.W.5    Grez, M.6
  • 95
    • 0037441756 scopus 로고    scopus 로고
    • Specific inhibition of bcr-abl gene expression by small interfering RNA
    • Scherr, M., Battmer, K., Winkler, T., Heidenreich, O., Ganser, A., and Eder, M. 2002. Specific inhibition of bcr-abl gene expression by small interfering RNA. Blood. 101:1566-1569.
    • (2002) Blood , vol.101 , pp. 1566-1569
    • Scherr, M.1    Battmer, K.2    Winkler, T.3    Heidenreich, O.4    Ganser, A.5    Eder, M.6
  • 98
    • 0001686739 scopus 로고    scopus 로고
    • Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
    • Shah, N.P., Nicoll, J.M., Nagar, B., Gorre, M.E., Paquette, R.L., Kuriyan, J., and Sawyers, C.L. 2002. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2:117-125.
    • (2002) Cancer Cell , vol.2 , pp. 117-125
    • Shah, N.P.1    Nicoll, J.M.2    Nagar, B.3    Gorre, M.E.4    Paquette, R.L.5    Kuriyan, J.6    Sawyers, C.L.7
  • 99
    • 0036782884 scopus 로고    scopus 로고
    • Telomerase: A target for cancer therapeutics
    • Shay, J.W., and Wright, W.E. 2002. Telomerase: a target for cancer therapeutics. Cancer Cell. 2:257-265.
    • (2002) Cancer Cell , vol.2 , pp. 257-265
    • Shay, J.W.1    Wright, W.E.2
  • 100
    • 0037468660 scopus 로고    scopus 로고
    • Gene silencing by adenovirus-delivered siRNA
    • Shen, C., Buck, A., Liu, X., Winkler, M., and Reske, S.N. 2003. Gene silencing by adenovirus-delivered siRNA. FEBS lett. 539:111-114.
    • (2003) FEBS Lett. , vol.539 , pp. 111-114
    • Shen, C.1    Buck, A.2    Liu, X.3    Winkler, M.4    Reske, S.N.5
  • 101
    • 0030670482 scopus 로고    scopus 로고
    • Myeloproliferative disease and myelodysplastic syndrome induced by transplantation of bone marrow cells expressing mutant p53
    • Shounan, Y., MacKenzie, K., Dolnikov, A., Miller, M., and Symonds, G. 1997. Myeloproliferative disease and myelodysplastic syndrome induced by transplantation of bone marrow cells expressing mutant p53. Leukemia. 11:1641-1649.
    • (1997) Leukemia , vol.11 , pp. 1641-1649
    • Shounan, Y.1    MacKenzie, K.2    Dolnikov, A.3    Miller, M.4    Symonds, G.5
  • 102
    • 0029785634 scopus 로고    scopus 로고
    • Retroviral transduction of hematopoietic progenitor cells with mutant p53 promotes survival and proliferation, modifies differentiation potential and inhibits apoptosis
    • Shounan, Y., Dolnikov, A., MacKenzie, K.L., Chan, Y-Y., and Symonds, G. 1996. Retroviral transduction of hematopoietic progenitor cells with mutant p53 promotes survival and proliferation, modifies differentiation potential and inhibits apoptosis. Leukemia. 10:1619-1628.
    • (1996) Leukemia , vol.10 , pp. 1619-1628
    • Shounan, Y.1    Dolnikov, A.2    MacKenzie, K.L.3    Chan, Y-Y.4    Symonds, G.5
  • 103
    • 0034711950 scopus 로고    scopus 로고
    • Design of nuclease resistant protein kinase C-alpha DNA enzymes with potential tharapeutic application
    • Sioud, M., and Leirdal, M., 2000. Design of nuclease resistant protein kinase C-alpha DNA enzymes with potential tharapeutic application. J. Mol. Biol. 296:937-947.
    • (2000) J. Mol. Biol. , vol.296 , pp. 937-947
    • Sioud, M.1    Leirdal, M.2
  • 104
    • 0031864708 scopus 로고    scopus 로고
    • A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth
    • Sioud, M., and Sorensen, D.R. 1998. A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth. Nat. Biotechnol. 16:556-561.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 556-561
    • Sioud, M.1    Sorensen, D.R.2
  • 105
    • 0027218359 scopus 로고
    • Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line
    • Snyder, D.S., Wu, Y., Wang, J.L., Rossi, J.J., Swiderski, P., Kaplan, B.E., and Forman, S.J. 1993. Ribozyme-mediated inhibition of bcr-abl gene expression in a Philadelphia chromosome-positive cell line. Blood. 82:600-605.
    • (1993) Blood , vol.82 , pp. 600-605
    • Snyder, D.S.1    Wu, Y.2    Wang, J.L.3    Rossi, J.J.4    Swiderski, P.5    Kaplan, B.E.6    Forman, S.J.7
  • 107
    • 0037119966 scopus 로고    scopus 로고
    • Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9
    • Spessotto, P., Rossi, F.M., Degan, M., Di Francia, R., Perris, R., Colombatti, A., and Gattei, V. 2002. Hyaluronan-CD44 interaction hampers migration of osteoclast-like cells by down-regulating MMP-9. J. Cell Biol. 158:1133-1144.
    • (2002) J. Cell Biol. , vol.158 , pp. 1133-1144
    • Spessotto, P.1    Rossi, F.M.2    Degan, M.3    Di Francia, R.4    Perris, R.5    Colombatti, A.6    Gattei, V.7
  • 108
    • 0033546334 scopus 로고    scopus 로고
    • Suppression of smooth muscle cell proliferation by a c-myc RNA-cleaving deoxyribozyme
    • Sun, L.Q., Cairns, M.J., Gerlach, W.L., Witherington, C., Wang, L., and King, A. 1999. Suppression of smooth muscle cell proliferation by a c-myc RNA-cleaving deoxyribozyme. J. Biol. Chem. 274:17236-17241.
    • (1999) J. Biol. Chem. , vol.274 , pp. 17236-17241
    • Sun, L.Q.1    Cairns, M.J.2    Gerlach, W.L.3    Witherington, C.4    Wang, L.5    King, A.6
  • 110
    • 0034576957 scopus 로고    scopus 로고
    • A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer
    • Tortora, G., Caputo, R., Damiano, V., Bianco, R., Chen, J., Agrawal, S., Bianco, A.R., and Ciardiello, F. 2000. A novel MDM2 anti-sense oligonucleotide has anti-tumor activity and potentiates cytotoxic drugs acting by different mechanisms in human colon cancer. Int. J. Cancer. 88: 804-809.
    • (2000) Int. J. Cancer , vol.88 , pp. 804-809
    • Tortora, G.1    Caputo, R.2    Damiano, V.3    Bianco, R.4    Chen, J.5    Agrawal, S.6    Bianco, A.R.7    Ciardiello, F.8
  • 111
    • 0023221419 scopus 로고
    • A small catalytic oligoribonucleotide
    • Uhlenbeck, O.C. 1987. A small catalytic oligoribonucleotide. Nature. 328:596-600.
    • (1987) Nature , vol.328 , pp. 596-600
    • Uhlenbeck, O.C.1
  • 112
  • 113
    • 0035186743 scopus 로고    scopus 로고
    • Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: In vitro and in vivo activities and mechanisms
    • Wang, H., Nan, L., Yu, D., Agrawal, S., and Zhang, R. 2001. Antisense anti-MDM2 oligonucleotides as a novel therapeutic approach to human breast cancer: in vitro and in vivo activities and mechanisms. Clin. Cancer Res. 7:3613-3624.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 3613-3624
    • Wang, H.1    Nan, L.2    Yu, D.3    Agrawal, S.4    Zhang, R.5
  • 114
    • 0033117651 scopus 로고    scopus 로고
    • Extremely high and specific activity of DNA enzymes in cells with a philadelphia chromosome
    • Warashina, M., Kuwabara, T., Nakamatsu, T., and Taira, K. 1999. Extremely high and specific activity of DNA enzymes in cells with a philadelphia chromosome. Chem. Biol. 6:237-250.
    • (1999) Chem. Biol. , vol.6 , pp. 237-250
    • Warashina, M.1    Kuwabara, T.2    Nakamatsu, T.3    Taira, K.4
  • 115
    • 0034682505 scopus 로고    scopus 로고
    • Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts
    • Watanabe, T., and Sullenger, B.A. 2000 Induction of wild-type p53 activity in human cancer cells by ribozymes that repair mutant p53 transcripts. Proc. Natl. Acad. Sci. USA. 97:8490-8494.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 8490-8494
    • Watanabe, T.1    Sullenger, B.A.2
  • 116
    • 0034015672 scopus 로고    scopus 로고
    • Phase I Clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-hodgkin's lymphoma
    • Waters, J.S., Webb, A., Cunningham, D., Clarke, P.A., Raynaud, F., di Stefano, F., and Cotter, F.E. 2000. Phase I Clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-hodgkin's lymphoma. J. Clin. Oncol. 18:1812-1823.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 1812-1823
    • Waters, J.S.1    Webb, A.2    Cunningham, D.3    Clarke, P.A.4    Raynaud, F.5    di Stefano, F.6    Cotter, F.E.7
  • 117
    • 0037158901 scopus 로고    scopus 로고
    • Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi)
    • Wilda, M., Fuchs, U., Wössmann, W., and Borkhardt, A. 2002. Killing of leukemic cells with a BCR/ABL fusion gene by RNA interference (RNAi). Oncogene. 21:5716-5724.
    • (2002) Oncogene , vol.21 , pp. 5716-5724
    • Wilda, M.1    Fuchs, U.2    Wössmann, W.3    Borkhardt, A.4
  • 119
    • 0037380839 scopus 로고    scopus 로고
    • Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells
    • Wu, H., Hait, W.N., and Yang, J-M. 2003. Small interfering RNA-induced suppression of MDR1 (P-glycoprotein) restores sensitivity to multidrug-resistant cancer cells. Cancer Res. 63:1515-1519.
    • (2003) Cancer Res. , vol.63 , pp. 1515-1519
    • Wu, H.1    Hait, W.N.2    Yang, J.-M.3
  • 120
    • 0032403264 scopus 로고    scopus 로고
    • Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells
    • Yokoyama, Y., Takahashi, Y., Shinohara, A., Lian, Z., Wan, X., Niwa, K., and Tamaya, T. 1998. Attenuation of telomerase activity by a hammerhead ribozyme targeting the template region of telomerase RNA in endometrial carcinoma cells. Cancer Res. 58:5406-5410.
    • (1998) Cancer Res. , vol.58 , pp. 5406-5410
    • Yokoyama, Y.1    Takahashi, Y.2    Shinohara, A.3    Lian, Z.4    Wan, X.5    Niwa, K.6    Tamaya, T.7
  • 122
    • 0344211452 scopus 로고    scopus 로고
    • Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer
    • Zhang, L., Yang, N., Mohamed-Hadley, A., Rubin, S.C., and Coukos, G. 2003. Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer. Biochem. Biophys. Res. Commun. 303:1169-1178.
    • (2003) Biochem. Biophys. Res. Commun. , vol.303 , pp. 1169-1178
    • Zhang, L.1    Yang, N.2    Mohamed-Hadley, A.3    Rubin, S.C.4    Coukos, G.5
  • 123
    • 0030807543 scopus 로고    scopus 로고
    • Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence
    • Ziegler, A., Luedke, G.H., Fabbro, D., Altmann, K.H., Stahel, R.A., and Zangemeister-Wittke, U. 1997. Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence. J. Natl. Cancer Inst. 89:1027-1036.
    • (1997) J. Natl. Cancer Inst. , vol.89 , pp. 1027-1036
    • Ziegler, A.1    Luedke, G.H.2    Fabbro, D.3    Altmann, K.H.4    Stahel, R.A.5    Zangemeister-Wittke, U.6
  • 124
    • 0028932288 scopus 로고
    • Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes
    • Zoumadakis, M., and Tabler, M. 1995. Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes. Nucleic Acids Res. 23:1192-96.
    • (1995) Nucleic Acids Res. , vol.23 , pp. 1192-1196
    • Zoumadakis, M.1    Tabler, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.