Targeting of PML/RARα is lethal to retinoic acid-resistant promyelocytic leukemia cells

Blood

Volumn 92, Issue 5, 1998, Pages 1758-1767

  Nason Burchenal, Kathryn ^a   Allopenna, Janet ^b   Bègue, Agnes ^b   Stéhelin, Dominique ^b   Dmitrovsky, Ethan ^b   Martin, Patrick ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

RETINOIC ACID; RETINOIC ACID RECEPTOR; ANTINEOPLASTIC AGENT; MESSENGER RNA; NUCLEAR PROTEIN; ONCOPROTEIN; PML PROTEIN, HUMAN; RECOMBINANT PROTEIN; RIBOZYME; TRANSCRIPTION FACTOR; TUMOR PROTEIN; TUMOR SUPPRESSOR PROTEIN;

AMINO ACID SEQUENCE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER REGRESSION; CHROMOSOME TRANSLOCATION 15; CHROMOSOME TRANSLOCATION 17; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; CELL CULTURE; CHROMOSOME 15; CHROMOSOME 17; DRUG RESISTANCE; GENE EXPRESSION; GENE TARGETING; GENE TRANSLOCATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE;

ANTINEOPLASTIC AGENTS; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 17; DNA MUTATIONAL ANALYSIS; DRUG RESISTANCE; GENE EXPRESSION; GENE TARGETING; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEOPLASM PROTEINS; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; RECEPTORS, RETINOIC ACID; RECOMBINANT PROTEINS; RNA, CATALYTIC; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSFECTION; TRANSLOCATION, GENETIC; TRETINOIN; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0032148358     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.5.1758     Document Type: Article

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