Specific hammerhead ribozyme-mediated cleavage of mutant N-ras mRNA in vitro and ex vivo: Oligoribonucleotides as therapeutic agents

Journal of Biological Chemistry

Volumn 272, Issue 22, 1997, Pages 14304-14313

  Scherr, Michaela ^a   Grez, Manuel ^b   Ganser, Arnold ^c   Engels, Joachim W ^a  

^a GOETHE UNIVERSITY   (Germany)

^b INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RIBOZYME;

ARTICLE; CONTROLLED STUDY; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; HELA CELL; HUMAN; HUMAN CELL; ONCOGENE N RAS; PRIORITY JOURNAL; RNA CLEAVAGE;

GENES, RAS; HELA CELLS; HUMANS; MASS SPECTROMETRY; OLIGONUCLEOTIDES; PLASMIDS; POINT MUTATION; RAS PROTEINS; RNA, CATALYTIC; RNA, MESSENGER;

EID: 0030920066     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.22.14304     Document Type: Article

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