Ribozyme-mediated suppression of v-myc expression abrogates apoptosis in transformed monocytes

Cancer Gene Therapy

Volumn 3, Issue 5, 1996, Pages 289-295

  Sun, Lun Quan ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

Apoptosis; Gene therapy; Ribozyme; V myc gene

Indexed keywords

DNA FRAGMENT; RIBOZYME;

AGAR GEL ELECTROPHORESIS; ANIMAL; APOPTOSIS; ARTICLE; CELL CLONE; CELL CULTURE; CELL CYCLE; CELL DIVISION; CHEMISTRY; CYTOCHEMISTRY; DRUG EFFECT; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETIC TRANSFORMATION; GENETICS; METABOLISM; MONOCYTE; MOUSE; NORTHERN BLOTTING; ONCOGENE MYC; PHYSIOLOGY; POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; BLOTTING, NORTHERN; CELL CYCLE; CELL DIVISION; CLONE CELLS; DNA FRAGMENTATION; ELECTROPHORESIS, AGAR GEL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, MYC; HISTOCYTOCHEMISTRY; MICE; MONOCYTES; POLYMERASE CHAIN REACTION; RNA, CATALYTIC; TRANSFORMATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0030229774     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (2)

1. Spencer CA, Groudine M. Control of c-myc regulation in normal and neoplastic cells. Adv. Cancer Res. 1992;56:1-48.
2. Kato GJ, Barrett J, Villa GM, et al. An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol Cell Biol. 1990;10:5914-5920.