Controlling the enantioselectivity of enzymes by directed evolution: Practical and theoretical ramifications

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 16, 2004, Pages 5716-5722

  Reetz, Manfred T ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EPOXIDE HYDROLASE; NITRILASE; TRANSITION ELEMENT; TRIACYLGLYCEROL LIPASE;

AMINO ACID SEQUENCE; ASYMMETRIC CATALYSIS; CATALYST; DNA SHUFFLING; ENANTIOSELECTIVITY; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; GENE EXPRESSION; HYBRID; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR EVOLUTION; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC CHEMISTRY; PRIORITY JOURNAL; REVIEW; STEREOCHEMISTRY;

DIRECTED MOLECULAR EVOLUTION; ENZYMES; HYDROGEN BONDING; MODELS, MOLECULAR; MUTAGENESIS; STEREOISOMERISM;

EID: 1942503297     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0306866101     Document Type: Review

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