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Angewandte Chemie - International Edition

Volumn 40, Issue 19, 2001, Pages 3589-3591

Directed evolution of an enantioselective enzyme through combinatorial multiple-cassette mutagenesis

(4) Reetz, Manfred T a,b Wilensek, Stephanie a,b Zha, Dongxing a Jaeger, Karl Erich a

a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG (Germany)

b RUHR UNIVERSITY BOCHUM (Germany)

Author keywords

Asymmetric catalysis; Combinatorial chemistry; Directed evolution; Enzyme catalysis; Lipases

Indexed keywords

CATALYST ACTIVITY; ENZYMES; ESTERS;

MUTANTS;

MUTAGENESIS;

ENZYME; GENE PRODUCT; PROTEIN RAC 1; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; ENANTIOMER; ENZYME KINETICS; ENZYME MECHANISM; ERROR; EVOLUTION; MUTAGENESIS; MUTANT; POLYMERASE CHAIN REACTION; STEREOCHEMISTRY;

EID: 0035477024 PISSN: 14337851 EISSN: None Source Type: Journal
DOI: 10.1002/1521-3773(20011001)40:19<3589::AID-ANIE3589>3.0.CO;2-X Document Type: Article

Times cited : (187)

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