Lipases as practical biocatalysts

Current Opinion in Chemical Biology

Volumn 6, Issue 2, 2002, Pages 145-150

  Reetz, Manfred T ^a  

^a MAX PLANCK INSTITUT FÜR KOHLENFORSCHUNG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ESTER DERIVATIVE; ORGANIC SOLVENT; TRIACYLGLYCEROL LIPASE; ORGANIC COMPOUND;

BIOCATALYST; CATALYSIS; CHIRALITY; ENANTIOSELECTIVITY; ENZYME ACTIVITY; GENETIC ENGINEERING; HYDROLYSIS; ORGANIC CHEMISTRY; REVIEW; SYNTHESIS; TEMPERATURE; DIRECTED MOLECULAR EVOLUTION; GENETICS; METABOLISM; PROTEIN ENGINEERING; STEREOISOMERISM;

CATALYSIS; DIRECTED MOLECULAR EVOLUTION; LIPASE; ORGANIC CHEMICALS; PROTEIN ENGINEERING; STEREOISOMERISM; SUPPORT, NON-U.S. GOV'T;

EID: 0036525716     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(02)00297-1     Document Type: Review

References (61)

1. Lipases: Interfacial enzymes with attractive applications
2. Bacterial biocatalysts: Molecular biology, three-dimensional structures, and biotechnological applications of lipases
3. Customizing lipases for biocatalysis: A survey of chemical, physical and molecular biological approaches
4. Enzymes for chemical synthesis
5. Industrial biocatalysis today and tomorrow
6. Improving enzymes by using them in organic solvents
7. 1-Ethoxyvinyl 2-furoate, an efficient acyl donor for the lipase-catalyzed enantioselective desymmetrization of prochiral 2,2-disubstituted propane-1,3-diols and meso-1,2-diols
8. Enhancing the enantioselectivity of lipase in transesterification by substrate matching: An enzyme memory based approach
9. Computer-aided control of water activity for lipase-catalyzed esterification in solvent-free systems
10. At what temperature can enzymes maintain their catalytic activity?
11. Enantioselective enzyme catalysed ammoniolysis of amino acid derivatives. Effect of temperature
12. Effects of substituent and temperature on enantioselectivity for lipase-catalyzed esterification of 2-(4-substituted phenoxy) propionic acids on organic solvents
13. Temperature and solvent effects on enzyme stereoselectivity: Inversion temperature in kinetic resolutions with lipases
14. Comparison of hydrolytic activity in water and heptane for thirty-two commercial lipase preparations
15. Enhanced activities of lipase pretreated with organic solvents
16. Properties and synthetic applications of enzymes in organic solvents
17. Lipase-catalyzed reactions in ionic liquids
18. Enzyme catalysis in ionic liquids: Lipase catalysed kinetic resolution of 1-phenylethanol with improved enantioselectivity
19. Biocatalysis in ionic liquids: Markedly enhanced enantioselectivity of lipase
20. Lipase-catalyzed enantioselective acylation in the ionic liquid solvent system: Reaction of enzyme anchored to the solvent
21. Over-stabilization of Candida antarctica lipase B by ionic liquids in ester synthesis
22. Control on enantioselectivity with pressure for lipase-catalyzed esterification in supercritical carbon dioxide
23. Enhancing effect of Tween-80 on lipase performance in enantioselective hydrolysis of ketoprofen ester
24. A new method for improving the enantioselectivity of lipase-catalyzed hydrolysis in organic solvent containing a small amount of water in the presence of metal ions
25. Tuning lipase enantioselectivity in organic media using solid-state buffers
26. Improving lipase enantioselectivity in organic solvents by forming substrate salts with chiral agents
27. Parallel kinetic resolution under catalytic conditions: A three-phase system allows selective reagent activation using two catalysts
28. Purification of lipase: A review
29. Entrapment of lipases in hydrophobic sol-gel-materials: Efficient heterogeneous biocatalysts in aqueous medium
30. Production and characterisation of cross-linked enzyme crystals (CLECs®) for application as process scale biocatalysts
31. Immobilisation of lipases by adsorption and deposition: High protein loading given lower water activity optimum
32. Preparation of new lipases derivatives with high activity-stability in anhydrous media: Adsorption on hydrophobic supports plus hydrophilization with polyethylenimine
33. Enzyme immobilization in silica-hardened organogels
34. Influence of the porous texture of silica gels on the enzymatic activity of lipases in esterification reactions
35. Enzymatic resolution of diltiazem intermediate by Serratia marcescens lipase: Molecular mechanism of lipase secretion and its industrial application
36. Molecular basis for enantioselectivity of lipase from Chromobacterium viscosum toward the diesters of 2,3-dihydro-3-(4′-hydroxyphenyl)-1,1,3-trimethyl-1H-inden-5-ol
37. Rational design of enantioselective enzymes requires considerations of entropy
38. Molecular basis of lipase stereoselectivity
39. Computer simulations of enantioselective ester hydrolyses catalyzed by Pseudomonas cepacia lipase
40. How do lipases and esterases work: The electrostatic contribution
41. Lipase protein engineering
42. Creation of an enantioselective hydrolase by engineered substrate-assisted catalysis
43. Improved enantioselectivity of a lipase by rational protein engineering
44. Combinatorial and computational challenges for biocatalyst design
45. Directed evolution and biocatalysis
46. Directed evolution of an enantioselective enzyme through combinatorial multiple-cassette mutagenesis
47. Combinatorial and evolution-based methods in the creation of enantioselective catalysts
48. Directed evolution: From a staphylococcal lipase to a phospholipase
49. Dynamic kinetic resolution of α hydroxy acid esters
50. Chemoenzymatic construction of a four-component Ugi combinatorial library
51. The synthesis of (+)-allopumiliotoxin 323B′
52. Enzyme-mediated synthesis of (S)- and (R)-verapamil
53. Enantioselective synthesis of the ricciocarpins A and B
54. A highly chemo- and stereoselective synthesis of β-keto esters via a polymer-supported lipase catalyzed transesterification
55. Introducing ChiPros™-biocatalytic production of chiral intermediates on a commercial scale
56. Enzymatic kinetic resolution of piperidine atropisomers: Synthesis of a key intermediate of the farnesyl protein transferase inhibitor, SCH66336
57. Multiselective enzymatic reactions for the synthesis of protected homochiral cis- and trans-1,3,5-cyclohexanetriols
58. An efficient synthesis of optical isomers of vasopressin V2 receptor antagonist OPC-41061 by lipase-catalyzed enantioselective transesterification
59. Regioselective enzymatic aminoacylation of lobucavir to give an intermediate for lobucavir prodrug
60. Enyzme-labile protecting groups in peptide synthesis: Development of glucose- and galactose-derived urethanes
61. Reversible Michael-enzymatic hydrolysis: A new variant of dynamic resolution