Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers

Nature Genetics

Volumn 26, Issue 3, 2000, Pages 291-299

  Jacobs, Jacqueline J L ^a   Keblusek, Petra ^a   Robanus Maandag, Els ^a   Kristel, Petra ^a   Lingbeek, Merel ^a   Nederlof, Petra M ^a   Van Welsem, Tibor ^a   Van De Vijver, Marc J ^a   Koh, Eugene Y ^b   Daley, George Q ^b   Van Lohuizen, Maarten ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA;

ARTICLE; BREAST CARCINOGENESIS; CELL CYCLE; DNA LIBRARY; DOWN REGULATION; GENE AMPLIFICATION; GENE INDUCTION; GENETIC SCREENING; HUMAN; ONCOGENE; PRIORITY JOURNAL; PROMOTER REGION; SENESCENCE;

ADENOCARCINOMA; ANIMALS; BREAST NEOPLASMS; CARRIER PROTEINS; CELL AGING; CELL CYCLE PROTEINS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 17; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; FEMALE; FIBROBLASTS; GENE AMPLIFICATION; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HUMANS; MICE; NEOPLASM PROTEINS; NEOPLASTIC SYNDROMES, HEREDITARY; NUCLEAR PROTEINS; ONCOGENES; PROMOTER REGIONS (GENETICS); PROTEIN BIOSYNTHESIS; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; PROTO-ONCOGENE PROTEINS P21(RAS); REPRESSOR PROTEINS; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 0033764030     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/81583     Document Type: Article

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