메뉴 건너뛰기




Volumn 8, Issue 5, 2005, Pages 677-688

Analysis of notch function in presomitic mesoderm suggests a γ-secretase-independent role for presenilins in somite differentiation

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE; NICASTRIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PRESENILIN 1; PRESENILIN 2;

EID: 17844390391     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.devcel.2005.02.019     Document Type: Article
Times cited : (130)

References (103)
  • 1
    • 0033737257 scopus 로고    scopus 로고
    • The developmental fate of the rostral/caudal half of a somite for vertebra and rib formation: Experimental confirmation of the resegmentation theory using chick-quail chimeras
    • H. Aoyama and K. Asamoto The developmental fate of the rostral/caudal half of a somite for vertebra and rib formation: Experimental confirmation of the resegmentation theory using chick-quail chimeras Mech. Dev. 99 2000 71-82
    • (2000) Mech. Dev. , vol.99 , pp. 71-82
    • Aoyama, H.1    Asamoto, K.2
  • 2
    • 0036778127 scopus 로고    scopus 로고
    • CSL-independent Notch signalling: A check point in cell fate decisions during development?
    • A.M. Arias V. Zecchini and K. Brennan CSL-independent Notch signalling: a check point in cell fate decisions during development? Curr. Opin. Genet. Dev. 12 2002 524-533
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 524-533
    • Arias, A.M.1    Zecchini, V.2    Brennan, K.3
  • 4
    • 4444256936 scopus 로고    scopus 로고
    • Segmentation in vertebrates: Clock and gradient finally joined
    • A. Aulehla and B.G. Herrmann Segmentation in vertebrates: Clock and gradient finally joined Genes Dev. 18 2004 2060-2067
    • (2004) Genes Dev. , vol.18 , pp. 2060-2067
    • Aulehla, A.1    Herrmann, B.G.2
  • 5
    • 0033104404 scopus 로고    scopus 로고
    • Dynamic expression of lunatic fringe suggests a link between Notch signaling and an autonomous cellular oscillator driving somite segmentation
    • A. Aulehla and R.L. Johnson Dynamic expression of lunatic fringe suggests a link between Notch signaling and an autonomous cellular oscillator driving somite segmentation Dev. Biol. 207 1999 49-61
    • (1999) Dev. Biol. , vol.207 , pp. 49-61
    • Aulehla, A.1    Johnson, R.L.2
  • 7
    • 3343005434 scopus 로고    scopus 로고
    • PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: Effects of FAD mutations
    • L. Baki J. Shioi P. Wen Z. Shao A. Schwarzman M. Gama-Sosa R. Neve and N.K. Robakis PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: Effects of FAD mutations EMBO J. 23 2004 2586-2596
    • (2004) EMBO J. , vol.23 , pp. 2586-2596
    • Baki, L.1    Shioi, J.2    Wen, P.3    Shao, Z.4    Schwarzman, A.5    Gama-Sosa, M.6    Neve, R.7    Robakis, N.K.8
  • 9
    • 0041845302 scopus 로고    scopus 로고
    • Oscillations, clocks and segmentation
    • Y. Bessho and R. Kageyama Oscillations, clocks and segmentation Curr. Opin. Genet. Dev. 13 2003 379-384
    • (2003) Curr. Opin. Genet. Dev. , vol.13 , pp. 379-384
    • Bessho, Y.1    Kageyama, R.2
  • 10
    • 0035887251 scopus 로고    scopus 로고
    • Dynamic expression and essential functions of Hes7 in somite segmentation
    • Y. Bessho R. Sakata S. Komatsu K. Shiota S. Yamada and R. Kageyama Dynamic expression and essential functions of Hes7 in somite segmentation Genes Dev. 15 2001 2642-2647
    • (2001) Genes Dev. , vol.15 , pp. 2642-2647
    • Bessho, Y.1    Sakata, R.2    Komatsu, S.3    Shiota, K.4    Yamada, S.5    Kageyama, R.6
  • 11
    • 0038046204 scopus 로고    scopus 로고
    • Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock
    • Y. Bessho H. Hirata Y. Masamizu and R. Kageyama Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock Genes Dev. 17 2003 1451-1456
    • (2003) Genes Dev. , vol.17 , pp. 1451-1456
    • Bessho, Y.1    Hirata, H.2    Masamizu, Y.3    Kageyama, R.4
  • 12
    • 0029023204 scopus 로고
    • Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely realted to Drosophila Delta
    • B. Bettenhausen M.H. de Angelis D. Simon J.-L. Guenet and A. Gossler Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely realted to Drosophila Delta Development 121 1995 2407-2418
    • (1995) Development , vol.121 , pp. 2407-2418
    • Bettenhausen, B.1    de Angelis, M.H.2    Simon, D.3    Guenet, J.-L.4    Gossler, A.5
  • 13
    • 0036013773 scopus 로고    scopus 로고
    • Notching up another pathway
    • K. Brennan and P. Gardner Notching up another pathway Bioessays 24 2002 405-410
    • (2002) Bioessays , vol.24 , pp. 405-410
    • Brennan, K.1    Gardner, P.2
  • 14
    • 2442710327 scopus 로고    scopus 로고
    • The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments
    • M. Bussen M. Petry K. Schuster-Gossler M. Leitges A. Gossler and A. Kispert The T-box transcription factor Tbx18 maintains the separation of anterior and posterior somite compartments Genes Dev. 18 2004 1209-1221
    • (2004) Genes Dev. , vol.18 , pp. 1209-1221
    • Bussen, M.1    Petry, M.2    Schuster-Gossler, K.3    Leitges, M.4    Gossler, A.5    Kispert, A.6
  • 15
    • 0142180318 scopus 로고    scopus 로고
    • γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney
    • H.-T. Cheng J.H. Miner M. Lin M.G. Tansey K. Roth and R. Kopan γ-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney Development 130 2003 5031-5042
    • (2003) Development , vol.130 , pp. 5031-5042
    • Cheng, H.-T.1    Miner, J.H.2    Lin, M.3    Tansey, M.G.4    Roth, K.5    Kopan, R.6
  • 16
    • 0028989016 scopus 로고
    • Notch1 is required for the coordinate segmentation of somites
    • R.A. Conlon A.G. Reaume and J. Rossant Notch1 is required for the coordinate segmentation of somites Development 121 1995 1533-1545
    • (1995) Development , vol.121 , pp. 1533-1545
    • Conlon, R.A.1    Reaume, A.G.2    Rossant, J.3
  • 17
    • 1842454974 scopus 로고    scopus 로고
    • Specification of vertebral identity is coupled to Notch signalling and the segmentation clock
    • R. Cordes K. Schuster-Gossler K. Serth and A. Gossler Specification of vertebral identity is coupled to Notch signalling and the segmentation clock Development 131 2004 1221-1233
    • (2004) Development , vol.131 , pp. 1221-1233
    • Cordes, R.1    Schuster-Gossler, K.2    Serth, K.3    Gossler, A.4
  • 18
    • 0033999283 scopus 로고    scopus 로고
    • Surface ectoderm is necessary for the morphogenesis of somites
    • K.M. Correia and R.A. Conlon Surface ectoderm is necessary for the morphogenesis of somites Mech. Dev. 91 2000 10-30
    • (2000) Mech. Dev. , vol.91 , pp. 10-30
    • Correia, K.M.1    Conlon, R.A.2
  • 19
    • 17844371861 scopus 로고    scopus 로고
    • Gamma Three Protease
    • Crouthamel, M.-C., Gardell, S.J., Huang, Q., Lai, M.-T., and Li, Y.(2002). Gamma Three Protease http://www.wipo.int/cgi-pct/guest/ ifetch5?ENG+PCT-ALL.vdb+14+1104408-SCORE+256+2+25312+BASICHTML-ENG +29+25275+26+25+SEP-0/HITNUM,B,,SCORE+gamma+OR+three+OR+protease
    • (2002)
    • Crouthamel, M.-C.1    Gardell, S.J.2    Huang, Q.3    Lai, M.-T.4    Li, Y.5
  • 20
    • 0037448536 scopus 로고    scopus 로고
    • Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock
    • J.K. Dale M. Maroto M.-L. Dequeant P. Malapert M. McGrew and O. Pourquie Periodic Notch inhibition by Lunatic Fringe underlies the chick segmentation clock Nature 421 2003 275-278
    • (2003) Nature , vol.421 , pp. 275-278
    • Dale, J.K.1    Maroto, M.2    Dequeant, M.-L.3    Malapert, P.4    McGrew, M.5    Pourquie, O.6
  • 21
    • 0030976083 scopus 로고    scopus 로고
    • Maintenance of somite borders in mice requires the Delta homologue Dll1
    • M.H. de Angelis J.I. McIntyre and A. Gossler Maintenance of somite borders in mice requires the Delta homologue Dll1 Nature 386 1997 717-721
    • (1997) Nature , vol.386 , pp. 717-721
    • de Angelis, M.H.1    McIntyre, J.I.2    Gossler, A.3
  • 26
    • 0032504991 scopus 로고    scopus 로고
    • Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation
    • H. Forsberg F. Crozet and N.A. Brown Waves of mouse Lunatic fringe expression, in four-hour cycles at two-hour intervals, precede somite boundary formation Curr. Biol. 8 1998 1027-1030
    • (1998) Curr. Biol. , vol.8 , pp. 1027-1030
    • Forsberg, H.1    Crozet, F.2    Brown, N.A.3
  • 27
    • 18444417998 scopus 로고    scopus 로고
    • aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
    • R. Francis G. McGrath J. Ahang D.A. Ruddy M. Sym J. Apfeld M. Nicoll M. Maxwell B. Hai M.C. Ellis et al. aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation Dev. Cell 3 2002 85-97
    • (2002) Dev. Cell , vol.3 , pp. 85-97
    • Francis, R.1    McGrath, G.2    Ahang, J.3    Ruddy, D.A.4    Sym, M.5    Apfeld, J.6    Nicoll, M.7    Maxwell, M.8    Hai, B.9    Ellis, M.C.10
  • 28
    • 8644219672 scopus 로고    scopus 로고
    • LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis
    • J. Galceran C. Sustmann S.-C. Hsu S. Folberth and R. Grosschedl LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis Genes Dev. 18 2004 2718-2723
    • (2004) Genes Dev. , vol.18 , pp. 2718-2723
    • Galceran, J.1    Sustmann, C.2    Hsu, S.-C.3    Folberth, S.4    Grosschedl, R.5
  • 31
    • 0032499199 scopus 로고    scopus 로고
    • A proteolytic system that compensates for loss of proteasome function
    • R. Glas M. Bogyo J.S. McMaster M. Gaczynska and H.L. Ploegh A proteolytic system that compensates for loss of proteasome function Nature 392 1998 618-622
    • (1998) Nature , vol.392 , pp. 618-622
    • Glas, R.1    Bogyo, M.2    McMaster, J.S.3    Gaczynska, M.4    Ploegh, H.L.5
  • 32
    • 0037418440 scopus 로고    scopus 로고
    • Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis
    • T.E. Golde and C.B. Eckman Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis Sci. STKE 172 2003 RE4
    • (2003) Sci. STKE , vol.172
    • Golde, T.E.1    Eckman, C.B.2
  • 33
    • 0030027060 scopus 로고    scopus 로고
    • Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development
    • T.L. Greco S. Takada M.M. Newhouse J.A. McMahon A.P. McMahon and S.A. Camper Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development Genes Dev. 10 1996 313-324
    • (1996) Genes Dev. , vol.10 , pp. 313-324
    • Greco, T.L.1    Takada, S.2    Newhouse, M.M.3    McMahon, J.A.4    McMahon, A.P.5    Camper, S.A.6
  • 34
    • 0032868937 scopus 로고    scopus 로고
    • Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality
    • Y. Hamada Y. Kadokawa M. Okabe M. Ikawa J.R. Coleman and Y. Tsujimoto Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality Development 126 1999 3415-3424
    • (1999) Development , vol.126 , pp. 3415-3424
    • Hamada, Y.1    Kadokawa, Y.2    Okabe, M.3    Ikawa, M.4    Coleman, J.R.5    Tsujimoto, Y.6
  • 35
    • 0242609960 scopus 로고    scopus 로고
    • Maternal inheritance of Cre activity in a Sox2Cre deleter strain
    • S. Hayashi Y. Tenzen and A.P. McMahon Maternal inheritance of Cre activity in a Sox2Cre deleter strain Genesis 37 2003 51-53
    • (2003) Genesis , vol.37 , pp. 51-53
    • Hayashi, S.1    Tenzen, Y.2    McMahon, A.P.3
  • 36
    • 13044278313 scopus 로고    scopus 로고
    • Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency
    • A. Herreman D. Hartmann W. Annaert P. Saftig K. Craessaerts L. Serneels L. Umans V. Schrijvers F. Checler H. Vanderstichele et al. Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency Proc. Natl. Acad. Sci. USA 96 1999 11872-11877
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11872-11877
    • Herreman, A.1    Hartmann, D.2    Annaert, W.3    Saftig, P.4    Craessaerts, K.5    Serneels, L.6    Umans, L.7    Schrijvers, V.8    Checler, F.9    Vanderstichele, H.10
  • 38
    • 0037444574 scopus 로고    scopus 로고
    • γ-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation
    • A. Herreman G.V. Gassen M. Bentahir O. Nyabi K. Craessaerts U. Mueller W. Annaert and B.D. Strooper γ-Secretase activity requires the presenilin-dependent trafficking of nicastrin through the Golgi apparatus but not its complex glycosylation J. Cell Sci. 116 2003 1127-1136
    • (2003) J. Cell Sci. , vol.116 , pp. 1127-1136
    • Herreman, A.1    Gassen, G.V.2    Bentahir, M.3    Nyabi, O.4    Craessaerts, K.5    Mueller, U.6    Annaert, W.7    Strooper, B.D.8
  • 41
    • 8644290897 scopus 로고    scopus 로고
    • WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomititc mesoderm of mouse embryos
    • M. Hofmann K. Schuster-Gossler M. Watabe-Rudolph A. Aulehla B.G. Herrmann and A. Gossler WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomititc mesoderm of mouse embryos Genes Dev. 18 2004 2712-2717
    • (2004) Genes Dev. , vol.18 , pp. 2712-2717
    • Hofmann, M.1    Schuster-Gossler, K.2    Watabe-Rudolph, M.3    Aulehla, A.4    Herrmann, B.G.5    Gossler, A.6
  • 42
    • 0034234968 scopus 로고    scopus 로고
    • Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity
    • S.A. Holley R. Geisler and C. Nusslein-Volhard Control of her1 expression during zebrafish somitogenesis by a Delta-dependent oscillator and an independent wave-front activity Genes Dev. 14 2000 1678-1690
    • (2000) Genes Dev. , vol.14 , pp. 1678-1690
    • Holley, S.A.1    Geisler, R.2    Nusslein-Volhard, C.3
  • 43
    • 0036332729 scopus 로고    scopus 로고
    • her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis
    • S.A. Holley D. Julich G.-J. Rauch R. Geisler and C. Nusslein-Volhard her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis Development 129 2002 1175-1183
    • (2002) Development , vol.129 , pp. 1175-1183
    • Holley, S.A.1    Julich, D.2    Rauch, G.-J.3    Geisler, R.4    Nusslein-Volhard, C.5
  • 46
    • 0035170555 scopus 로고    scopus 로고
    • The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice
    • J. Johnson J. Rhee S.M. Parsons D. Brown E.N. Olson and A. Rawls The anterior/posterior polarity of somites is disrupted in paraxis-deficient mice Dev. Biol. 229 2001 176-187
    • (2001) Dev. Biol. , vol.229 , pp. 176-187
    • Johnson, J.1    Rhee, J.2    Parsons, S.M.3    Brown, D.4    Olson, E.N.5    Rawls, A.6
  • 47
    • 0034098483 scopus 로고    scopus 로고
    • Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm
    • C. Jouve I. Palmeirim D. Henrique J. Beckers A. Gossler D. Ish-Horowicz and O. Pourquie Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm Development 127 2000 1421-1429
    • (2000) Development , vol.127 , pp. 1421-1429
    • Jouve, C.1    Palmeirim, I.2    Henrique, D.3    Beckers, J.4    Gossler, A.5    Ish-Horowicz, D.6    Pourquie, O.7
  • 48
    • 0037145062 scopus 로고    scopus 로고
    • Presenilin couples the paired phosphorylation of beta-catenin independent of axin. Implications for beta-catenin activation in tumorigenesis
    • D. Kang S. Soriano X. Xia C. Eberhart B. De Strooper H. Zheng and E. Koo Presenilin couples the paired phosphorylation of beta-catenin independent of axin. Implications for beta-catenin activation in tumorigenesis Cell 110 2002 751-762
    • (2002) Cell , vol.110 , pp. 751-762
    • Kang, D.1    Soriano, S.2    Xia, X.3    Eberhart, C.4    De Strooper, B.5    Zheng, H.6    Koo, E.7
  • 50
    • 0345689442 scopus 로고    scopus 로고
    • Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation
    • L.T. Krebs Y. Xue C.R. Norton J.P. Sundberg P. Beatus U. Lendahl A. Joutel and T. Gridley Characterization of Notch3-deficient mice: Normal embryonic development and absence of genetic interactions with a Notch1 mutation Genesis 37 2003 139-143
    • (2003) Genesis , vol.37 , pp. 139-143
    • Krebs, L.T.1    Xue, Y.2    Norton, C.R.3    Sundberg, J.P.4    Beatus, P.5    Lendahl, U.6    Joutel, A.7    Gridley, T.8
  • 51
    • 0036828975 scopus 로고    scopus 로고
    • Cell dynamics during somite boundary formation revealed by time-lapse analysis
    • P.M. Kulesa and S.E. Fraser Cell dynamics during somite boundary formation revealed by time-lapse analysis Science 298 2002 991-995
    • (2002) Science , vol.298 , pp. 991-995
    • Kulesa, P.M.1    Fraser, S.E.2
  • 52
    • 0034331260 scopus 로고    scopus 로고
    • Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors
    • C. Leimeister K. Dale A. Fischer B. Klamt M. Hrabe de Angelis F. Radtke M.J. McGrew O. Pourquie and M. Gessler Oscillating expression of c-Hey2 in the presomitic mesoderm suggests that the segmentation clock may use combinatorial signaling through multiple interacting bHLH factors Dev. Biol. 227 2000 91-103
    • (2000) Dev. Biol. , vol.227 , pp. 91-103
    • Leimeister, C.1    Dale, K.2    Fischer, A.3    Klamt, B.4    Hrabe de Angelis, M.5    Radtke, F.6    McGrew, M.J.7    Pourquie, O.8    Gessler, M.9
  • 53
    • 0036809216 scopus 로고    scopus 로고
    • Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis
    • M.K. Lemberg and B. Martoglio Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis Mol. Cell 10 2002 735-744
    • (2002) Mol. Cell , vol.10 , pp. 735-744
    • Lemberg, M.K.1    Martoglio, B.2
  • 54
    • 0041677612 scopus 로고    scopus 로고
    • Autoinhibition with transcriptional delay: A simple mechanism for the zebrafish somitogenesis oscillator
    • J. Lewis Autoinhibition with transcriptional delay: A simple mechanism for the zebrafish somitogenesis oscillator Curr. Biol. 13 2003 1398-1408
    • (2003) Curr. Biol. , vol.13 , pp. 1398-1408
    • Lewis, J.1
  • 56
    • 0037659067 scopus 로고    scopus 로고
    • Nicastrin is required for assembly of presenilin/γ-secretase complexes to mediate Notch signaling and for processing and trafficking of β-amyloid precursor protein in mammals
    • T. Li G. Ma H. Cai D.L. Price and P.C. Wong Nicastrin is required for assembly of presenilin/γ-secretase complexes to mediate Notch signaling and for processing and trafficking of β-amyloid precursor protein in mammals J. Neurosci. 23 2003 3272-3277
    • (2003) J. Neurosci. , vol.23 , pp. 3272-3277
    • Li, T.1    Ma, G.2    Cai, H.3    Price, D.L.4    Wong, P.C.5
  • 57
    • 12144250683 scopus 로고    scopus 로고
    • APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development
    • G. Ma T. Li D.L. Price and P.C. Wong APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development J. Neurosci. 25 2005 192-198
    • (2005) J. Neurosci. , vol.25 , pp. 192-198
    • Ma, G.1    Li, T.2    Price, D.L.3    Wong, P.C.4
  • 58
    • 0035228344 scopus 로고    scopus 로고
    • A molecular clock involved in somite segmentation
    • M. Maroto and O. Pourquie A molecular clock involved in somite segmentation Curr. Top. Dev. Biol. 51 2001 221-248
    • (2001) Curr. Top. Dev. Biol. , vol.51 , pp. 221-248
    • Maroto, M.1    Pourquie, O.2
  • 59
    • 0141994826 scopus 로고    scopus 로고
    • Intramembrane-cleaving aspartic proteases and disease: Presenilins, signal peptide peptidase and their homologs
    • B. Martoglio and T.E. Golde Intramembrane-cleaving aspartic proteases and disease: Presenilins, signal peptide peptidase and their homologs Hum. Mol. Genet. 12 2003 R201-R206
    • (2003) Hum. Mol. Genet. , vol.12
    • Martoglio, B.1    Golde, T.E.2
  • 62
    • 0030668283 scopus 로고    scopus 로고
    • A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system
    • L.M. Neidhardt A. Kispert and B.G. Herrmann A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system Dev. Genes Evol. 207 1997 330-339
    • (1997) Dev. Genes Evol. , vol.207 , pp. 330-339
    • Neidhardt, L.M.1    Kispert, A.2    Herrmann, B.G.3
  • 63
    • 0036337993 scopus 로고    scopus 로고
    • Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis
    • A. Nomura-Kitabayashi Y. Takahashi S. Kitajima T. Inoue H. Takeda and Y. Saga Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis Development 129 2002 2473-2481
    • (2002) Development , vol.129 , pp. 2473-2481
    • Nomura-Kitabayashi, A.1    Takahashi, Y.2    Kitajima, S.3    Inoue, T.4    Takeda, H.5    Saga, Y.6
  • 64
    • 5644240819 scopus 로고    scopus 로고
    • An Spp reporter activity assay based on the cleavage of a Type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin
    • A.C. Nyborg K. Jansen T.B. Ladd A. Fauq and T.E. Golde An Spp reporter activity assay based on the cleavage of a Type II membrane protein substrates provides further evidence for an inverted orientation of the SPP active site relative to presenilin J. Biol. Chem. 279 2004 43148-43156
    • (2004) J. Biol. Chem. , vol.279 , pp. 43148-43156
    • Nyborg, A.C.1    Jansen, K.2    Ladd, T.B.3    Fauq, A.4    Golde, T.E.5
  • 66
    • 7744240345 scopus 로고    scopus 로고
    • γ-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis
    • Y. Pan M.-H. Lin X. Tian H.-T. Cheng T. Gridley J. Shen and R. Kopan γ-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis Dev. Cell 7 2004 731-743
    • (2004) Dev. Cell , vol.7 , pp. 731-743
    • Pan, Y.1    Lin, M.-H.2    Tian, X.3    Cheng, H.-T.4    Gridley, T.5    Shen, J.6    Kopan, R.7
  • 69
    • 0038115065 scopus 로고    scopus 로고
    • The segmentation clock: Converting embryonic time into spatial pattern
    • O. Pourquie The segmentation clock: Converting embryonic time into spatial pattern Science 301 2003 328-330
    • (2003) Science , vol.301 , pp. 328-330
    • Pourquie, O.1
  • 70
    • 3543138873 scopus 로고    scopus 로고
    • The chick embryo: A leading model in somitogenesis studies
    • O. Pourquie The chick embryo: A leading model in somitogenesis studies Mech. Dev. 121 2004 1069-1079
    • (2004) Mech. Dev. , vol.121 , pp. 1069-1079
    • Pourquie, O.1
  • 71
    • 0346362323 scopus 로고    scopus 로고
    • A Notch feeling of somite segmentation and beyond
    • P.C.G. Rida N.L. Minh and Y.-J. Jiang A Notch feeling of somite segmentation and beyond Dev. Biol. 265 2004 2-22
    • (2004) Dev. Biol. , vol.265 , pp. 2-22
    • Rida, P.C.G.1    Minh, N.L.2    Jiang, Y.-J.3
  • 74
    • 0035514186 scopus 로고    scopus 로고
    • The making of the somite: Molecular events in vertebrate segmentation
    • Y. Saga and H. Takeda The making of the somite: Molecular events in vertebrate segmentation Nat. Rev. Genet. 2 2001 835-845
    • (2001) Nat. Rev. Genet. , vol.2 , pp. 835-845
    • Saga, Y.1    Takeda, H.2
  • 75
    • 0036678153 scopus 로고    scopus 로고
    • Morphological boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation
    • Y. Sato K. Yasuda and Y. Takahashi Morphological boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation Development 129 2002 3633-3644
    • (2002) Development , vol.129 , pp. 3633-3644
    • Sato, Y.1    Yasuda, K.2    Takahashi, Y.3
  • 76
    • 0034090969 scopus 로고    scopus 로고
    • Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites
    • A. Sawada A. Fritz Y.-J. Jiang A. Yamamoto K. Yamasu A. Kuroiwa Y. Saga and H. Takeda Zebrafish Mesp family genes, mesp-a and mesp-b are segmentally expressed in the presomitic mesoderm, and Mesp-b confers the anterior identity to the developing somites Development 127 2000 1691-1702
    • (2000) Development , vol.127 , pp. 1691-1702
    • Sawada, A.1    Fritz, A.2    Jiang, Y.-J.3    Yamamoto, A.4    Yamasu, K.5    Kuroiwa, A.6    Saga, Y.7    Takeda, H.8
  • 77
    • 0035955604 scopus 로고    scopus 로고
    • Murine Notch homologs (N1-4) undergo presenilin-dependent proteolysis
    • M.T. Saxena E.H. Schroeter J.S. Mumm and R. Kopan Murine Notch homologs (N1-4) undergo presenilin-dependent proteolysis J. Biol. Chem. 276 2001 40268-40273
    • (2001) J. Biol. Chem. , vol.276 , pp. 40268-40273
    • Saxena, M.T.1    Schroeter, E.H.2    Mumm, J.S.3    Kopan, R.4
  • 78
    • 0032574993 scopus 로고    scopus 로고
    • Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
    • E.H. Schroeter J.A. Kisslinger and R. Kopan Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain Nature 393 1998 382-386
    • (1998) Nature , vol.393 , pp. 382-386
    • Schroeter, E.H.1    Kisslinger, J.A.2    Kopan, R.3
  • 81
    • 0037380655 scopus 로고    scopus 로고
    • Transcriptional oscillation of Lunatic fringe is essential for somitogenesis
    • K. Serth K. Schuster-Gossler R. Cordes and A. Gossler Transcriptional oscillation of Lunatic fringe is essential for somitogenesis Genes Dev. 17 2003 912-925
    • (2003) Genes Dev. , vol.17 , pp. 912-925
    • Serth, K.1    Schuster-Gossler, K.2    Cordes, R.3    Gossler, A.4
  • 83
    • 0035911156 scopus 로고    scopus 로고
    • Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and Notch processing
    • S. Soriano D.E. Kang M.F. Fu R. Pestell N. Chevallier H. Zheng and E.H. Koo Presenilin 1 negatively regulates beta-catenin/T cell factor/ lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and Notch processing J. Cell Biol. 152 2001 785-794
    • (2001) J. Cell Biol. , vol.152 , pp. 785-794
    • Soriano, S.1    Kang, D.E.2    Fu, M.F.3    Pestell, R.4    Chevallier, N.5    Zheng, H.6    Koo, E.H.7
  • 85
    • 0034103657 scopus 로고    scopus 로고
    • Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development
    • X. Sun M. Lewandoski E.N. Meyers Y.H. Liu R.E. Maxson Jr. and G.R. Martin Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development Nat. Genet. 25 2000 83-86
    • (2000) Nat. Genet. , vol.25 , pp. 83-86
    • Sun, X.1    Lewandoski, M.2    Meyers, E.N.3    Liu, Y.H.4    Maxson Jr., R.E.5    Martin, G.R.6
  • 89
    • 0141613751 scopus 로고    scopus 로고
    • Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites
    • Y. Takahashi T. Inoue A. Gossler and Y. Saga Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites Development 130 2003 4259-4268
    • (2003) Development , vol.130 , pp. 4259-4268
    • Takahashi, Y.1    Inoue, T.2    Gossler, A.3    Saga, Y.4
  • 92
    • 0038771224 scopus 로고    scopus 로고
    • Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
    • S. Urban and M. Freeman Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain Mol. Cell 11 2003 1425-1434
    • (2003) Mol. Cell , vol.11 , pp. 1425-1434
    • Urban, S.1    Freeman, M.2
  • 93
    • 0242441595 scopus 로고    scopus 로고
    • Highly efficient transgene-independent recombination directed by a maternally derived Sox2Cre transgene
    • S.D. Vincent and E.J. Robertson Highly efficient transgene-independent recombination directed by a maternally derived Sox2Cre transgene Genesis 37 2003 54-56
    • (2003) Genesis , vol.37 , pp. 54-56
    • Vincent, S.D.1    Robertson, E.J.2
  • 94
    • 0029417192 scopus 로고
    • RBP-Jk repression activity is mediated by a co-repressor and antagolized by the Epstein-Barr virus transcription factor EBNA2
    • L. Waltzer P.Y. Bourillot A. Sergeant and E. Manet RBP-Jk repression activity is mediated by a co-repressor and antagolized by the Epstein-Barr virus transcription factor EBNA2 Nucleic Acids Res. 23 1995 4939-4945
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4939-4945
    • Waltzer, L.1    Bourillot, P.Y.2    Sergeant, A.3    Manet, E.4
  • 95
    • 0037304947 scopus 로고    scopus 로고
    • Intramembrane-cleaving proteases: Controlled liberation of proteins and bioactive peptides
    • A. Weihofen and B. Martoglio Intramembrane-cleaving proteases: controlled liberation of proteins and bioactive peptides Trends Cell Biol. 13 2003 71-78
    • (2003) Trends Cell Biol. , vol.13 , pp. 71-78
    • Weihofen, A.1    Martoglio, B.2
  • 96
    • 0037150672 scopus 로고    scopus 로고
    • Identification of signal peptide peptidase, a presenilin-type aspartic protease
    • A. Weihofen K. Binns M.K. Lemberg K. Ashman and B. Martoglio Identification of signal peptide peptidase, a presenilin-type aspartic protease Science 296 2002 2215-2218
    • (2002) Science , vol.296 , pp. 2215-2218
    • Weihofen, A.1    Binns, K.2    Lemberg, M.K.3    Ashman, K.4    Martoglio, B.5
  • 98
    • 0242298785 scopus 로고    scopus 로고
    • Distinct presenilin-dependent and presenilin-independent γ-secretases are responsible for total cellular Aβ production
    • C.A. Wilson R.W. Doms and V.M.-Y. Lee Distinct presenilin-dependent and presenilin-independent γ-secretases are responsible for total cellular Aβ production J. Neurosci. Res. 74 2003 361-369
    • (2003) J. Neurosci. Res. , vol.74 , pp. 361-369
    • Wilson, C.A.1    Doms, R.W.2    Lee, V.M.-Y.3
  • 100
    • 16844367458 scopus 로고    scopus 로고
    • Functional overexpression of gamma-secretase reveals protease independent trafficking functions and a critical role of lipids for protease activity
    • J.D. Wrigley I. Schurov E.J. Nunn A.C. Martin E.E. Clarke S. Ellis T.P. Bonnert M.S. Shearman and D. Beher Functional overexpression of gamma-secretase reveals protease independent trafficking functions and a critical role of lipids for protease activity J. Biol. Chem. 280 2004 12523-12535
    • (2004) J. Biol. Chem. , vol.280 , pp. 12523-12535
    • Wrigley, J.D.1    Schurov, I.2    Nunn, E.J.3    Martin, A.C.4    Clarke, E.E.5    Ellis, S.6    Bonnert, T.P.7    Shearman, M.S.8    Beher, D.9
  • 101
    • 1842665708 scopus 로고    scopus 로고
    • Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway
    • X. Yang R. Klein X. Tian H.-T. Cheng R. Kopan and J. Shen Notch activation induces apoptosis in neural progenitor cells through a p53-dependent pathway Dev. Biol. 269 2004 81-94
    • (2004) Dev. Biol. , vol.269 , pp. 81-94
    • Yang, X.1    Klein, R.2    Tian, X.3    Cheng, H.-T.4    Kopan, R.5    Shen, J.6
  • 102
    • 0033779635 scopus 로고    scopus 로고
    • Presenilins are required for γ-secretase cleavage of β-APP and transmemebrane cleavage of Notch-1
    • Z. Zhang P. Nadeau W. Song D. Donoviel M. Yuan A. Berstein and B.A. Yankner Presenilins are required for γ-secretase cleavage of β-APP and transmemebrane cleavage of Notch-1 Nat. Cell Biol. 2 2000 463-465
    • (2000) Nat. Cell Biol. , vol.2 , pp. 463-465
    • Zhang, Z.1    Nadeau, P.2    Song, W.3    Donoviel, D.4    Yuan, M.5    Berstein, A.6    Yankner, B.A.7
  • 103
    • 0036267319 scopus 로고    scopus 로고
    • Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice
    • N. Zhang C.R. Norton and T. Gridley Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/ radical fringe double mutant mice Genesis 33 2002 21-28
    • (2002) Genesis , vol.33 , pp. 21-28
    • Zhang, N.1    Norton, C.R.2    Gridley, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.