-
1
-
-
0014201592
-
Three-dimensional structure of tosyl-α-chymotrypsin
-
Matthews, B. W., Sigler, P. B., Henderson, R. & Blow, D. M. Three-dimensional structure of tosyl-α-chymotrypsin. Nature 214, 652-656 (1967).
-
(1967)
Nature
, vol.214
, pp. 652-656
-
-
Matthews, B.W.1
Sigler, P.B.2
Henderson, R.3
Blow, D.M.4
-
3
-
-
0031301274
-
Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs
-
Rawson, R. B. et al. Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Mol. Cell 1, 47-57 (1997).
-
(1997)
Mol. Cell
, vol.1
, pp. 47-57
-
-
Rawson, R.B.1
-
4
-
-
0033535553
-
Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
-
Wolfe, M. S. et al. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity. Nature 398, 513-517 (1999).
-
(1999)
Nature
, vol.398
, pp. 513-517
-
-
Wolfe, M.S.1
-
5
-
-
0034621824
-
Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1
-
Li, Y. M. et al. Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1. Nature 405, 689-694 (2000).
-
(2000)
Nature
, vol.405
, pp. 689-694
-
-
Li, Y.M.1
-
6
-
-
0033780472
-
Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1
-
Esler, W. P. et al. Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1. Nature Cell Biol. 2, 428-434(2000).
-
(2000)
Nature Cell Biol.
, vol.2
, pp. 428-434
-
-
Esler, W.P.1
-
7
-
-
0037150672
-
Identification of signal peptide peptidase, a presenilin-type aspartic protease
-
Weihofn, A., Binns, K., Lemberg, M. K., Ashman, K. & Martoglio, B. Identification of signal peptide peptidase, a presenilin-type aspartic protease. Science 296, 2215-2218 (2002).
-
(2002)
Science
, vol.296
, pp. 2215-2218
-
-
Weihofn, A.1
Binns, K.2
Lemberg, M.K.3
Ashman, K.4
Martoglio, B.5
-
8
-
-
0035913908
-
Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases
-
Urban, S., Lee, J. R. & Freeman, M. Drosophila Rhomboid-1 defines a family of putative intramembrane serine proteases. Cell 107, 173-182 (2001). This paper reports the discovery that rhomboids are a new, conserved family of intramembrane serine proteases.
-
(2001)
Cell
, vol.107
, pp. 173-182
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
9
-
-
0034234250
-
A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhombcid-3 cooperate to activate EGF receptor signalling
-
Wasserman, J. D., Urban, S. & Freeman, M. A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhombcid-3 cooperate to activate EGF receptor signalling. Genes Dev. 14, 1651-1663 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 1651-1663
-
-
Wasserman, J.D.1
Urban, S.2
Freeman, M.3
-
10
-
-
0034667916
-
Brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling
-
Guichard, A., Roark, M., Ronshaugen, M. & Bier, E. brother of rhomboid, a rhomboid-related gene expressed during early Drosophila oogenesis, promotes EGF-R/MAPK signaling. Dev. Biol. 226, 255-266 (2000).
-
(2000)
Dev. Biol.
, vol.226
, pp. 255-266
-
-
Guichard, A.1
Roark, M.2
Ronshaugen, M.3
Bier, E.4
-
11
-
-
0037264371
-
The rhomboids: A nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers
-
Koonin, E. V. et al. The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers. Genome Biol. 4, R19 (2003). This paper describes a detailed phylogenetic analysis of rhomboids and points out that they are the most widely conserved polytopic, membrane proteins.
-
(2003)
Genome Biol.
, vol.4
-
-
Koonin, E.V.1
-
12
-
-
34250134008
-
Mutations affecting the pattem of the larval cuticle in Drosophila melanogaster. II. Zygotic loci on the third chromosome
-
Jürgene, G., Wieschaus, E, Nüsslein-Volhard, C. & Kluding, H. Mutations affecting the pattem of the larval cuticle in Drosophila melanogaster. II. Zygotic loci on the third chromosome. Wilhelm Roux's Arch. Dev. Biol. 193, 283-295 (1984).
-
(1984)
Wilhelm Roux's Arch. Dev. Biol.
, vol.193
, pp. 283-295
-
-
Jürgene, G.1
Wieschaus, E.2
Nüsslein-Volhard, C.3
Kluding, H.4
-
13
-
-
0024114027
-
A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo
-
Mayer, U. & Nüsslein-Volhard, C. A group of genes required for pattern formation in the ventral ectoderm of the Drosophila embryo. Genes Dev. 2, 1496-1511 (1988).
-
(1988)
Genes Dev.
, vol.2
, pp. 1496-1511
-
-
Mayer, U.1
Nüsslein-Volhard, C.2
-
14
-
-
0031005779
-
A thousand and one roles for the Drosophila EGF receptor
-
Schweitzer, R. & Shilo, B.-Z. A thousand and one roles for the Drosophila EGF receptor. Trends Genet. 13, 191-196 (1997).
-
(1997)
Trends Genet.
, vol.13
, pp. 191-196
-
-
Schweitzer, R.1
Shilo, B.-Z.2
-
16
-
-
0026459770
-
Identifying targets of the rough homeobox gene of Drosophila: Evidence that rhomboid functions in eye development
-
Freeman, M., Kimmel, B. E. & Rubin, G. M. Identifying targets of the rough homeobox gene of Drosophila: evidence that rhomboid functions in eye development. Development 116, 335-346 (1992).
-
(1992)
Development
, vol.116
, pp. 335-346
-
-
Freeman, M.1
Kimmel, B.E.2
Rubin, G.M.3
-
17
-
-
0025060344
-
Rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster
-
Bier, E., Jan, L. Y. & Jan, Y. N. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes Dev. 4, 190-203 (1990).
-
(1990)
Genes Dev.
, vol.4
, pp. 190-203
-
-
Bier, E.1
Jan, L.Y.2
Jan, Y.N.3
-
18
-
-
0027176294
-
The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway
-
Sturtevant, M. A., Roark, M. & Bier, E. The Drosophila rhomboid gene mediates the localized formation of wing veins and interacts genetically with components of the EGF-R signaling pathway. Genes Dev. 7, 961-973 (1993).
-
(1993)
Genes Dev.
, vol.7
, pp. 961-973
-
-
Sturtevant, M.A.1
Roark, M.2
Bier, E.3
-
19
-
-
0027157553
-
Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis
-
Ruohola-Baker, H. et al. Spatially localized rhomboid is required for establishment of the dorsal-ventral axis in Drosophila oogenesis. Cell 73, 953-965 (1993).
-
(1993)
Cell
, vol.73
, pp. 953-965
-
-
Ruohola-Baker, H.1
-
20
-
-
0028059268
-
The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor
-
Freeman, M. The spitz gene is required for photoreceptor determination in the Drosophila eye where it interacts with the EGF receptor. Mech. Mach. Dev 48, 25-33 (1994).
-
(1994)
Mech. Mach. Dev.
, vol.48
, pp. 25-33
-
-
Freeman, M.1
-
21
-
-
0037429688
-
Signaling by the Drosophila epidermal growth factor receptor pathway during development
-
Shilo, B. Z. Signaling by the Drosophila epidermal growth factor receptor pathway during development. Exp. Cell Res. 284, 140-149 (2003).
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 140-149
-
-
Shilo, B.Z.1
-
22
-
-
0029855245
-
The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
-
Golembo, M., Raz, E. & Shilo, B. Z. The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122, 3363-3370 (1996).
-
(1996)
Development
, vol.122
, pp. 3363-3370
-
-
Golembo, M.1
Raz, E.2
Shilo, B.Z.3
-
23
-
-
0032774518
-
Rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development
-
Guichard, A. et al. rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development. Development 126, 2663-2676 (1999). An elegant genetic demonstration that D. melanogaster Rhomboid-1 and Star function co-dependently to activate EGFR signalling.
-
(1999)
Development
, vol.126
, pp. 2663-2676
-
-
Guichard, A.1
-
24
-
-
0032582797
-
An autoregulatory cascade of EGF receptor signalling patterns the Drosophila egg
-
Wasserman, J. D. & Freeman, M. An autoregulatory cascade of EGF receptor signalling patterns the Drosophila egg. Cell 95, 355-364 (1998).
-
(1998)
Cell
, vol.95
, pp. 355-364
-
-
Wasserman, J.D.1
Freeman, M.2
-
25
-
-
0031092699
-
Requirement for EGF receptor signalling in neural recruitment during formation of Drosophila chordotonal sense organ clusters
-
zür Lage, P., Jan, Y. N. & Jarman, A. P. Requirement for EGF receptor signalling in neural recruitment during formation of Drosophila chordotonal sense organ clusters. Curr. Biol. 7, 166-175 (1997).
-
(1997)
Curr. Biol.
, vol.7
, pp. 166-175
-
-
Zür Lage, P.1
Jan, Y.N.2
Jarman, A.P.3
-
26
-
-
0033678762
-
Regulation of Drosophila wing vein patterning: Net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling
-
Brentrup, D., Lerch, H., Jackle, H. & Noll, M. Regulation of Drosophila wing vein patterning: net encodes a bHLH protein repressing rhomboid and is repressed by rhomboid-dependent Egfr signalling. Development 127, 4729-4741 (2000).
-
(2000)
Development
, vol.127
, pp. 4729-4741
-
-
Brentrup, D.1
Lerch, H.2
Jackle, H.3
Noll, M.4
-
27
-
-
0030866482
-
In situ activation pattern of Drosophila EGF receptor pathway during development
-
Gabay, L., Seger, R. & Shilo, B.-Z. In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277, 1103-1106 (1997).
-
(1997)
Science
, vol.277
, pp. 1103-1106
-
-
Gabay, L.1
Seger, R.2
Shilo, B.-Z.3
-
28
-
-
0028142324
-
New functions of the Drosophila rhomboid gene during embryonic and adult development are revealed by a novel genetic method, enhancer piracy
-
Noll, R., Sturtevant, M. A., Gollapudi, R. R. & Bier, E. New functions of the Drosophila rhomboid gene during embryonic and adult development are revealed by a novel genetic method, enhancer piracy. Development 120, 2329-2338 (1994).
-
(1994)
Development
, vol.120
, pp. 2329-2338
-
-
Noll, R.1
Sturtevant, M.A.2
Gollapudi, R.R.3
Bier, E.4
-
29
-
-
0028954113
-
Analysis of the genetic hierarchy guiding wing vein development in Drosophila
-
Sturtevant, M. A. & Bier, E. Analysis of the genetic hierarchy guiding wing vein development in Drosophila. Development 121, 785-801 (1995).
-
(1995)
Development
, vol.121
, pp. 785-801
-
-
Sturtevant, M.A.1
Bier, E.2
-
30
-
-
0028363844
-
Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila
-
Kolodkin, A. L, Pickup, A. T., Lin, D. M., Goodman, C. S. & Banerjee, U. Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila. Development 120, 1731-1745 (1994).
-
(1994)
Development
, vol.120
, pp. 1731-1745
-
-
Kolodkin, A.L.1
Pickup, A.T.2
Lin, D.M.3
Goodman, C.S.4
Banerjee, U.5
-
31
-
-
0034650255
-
Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-α homolog Spitz
-
Bang, A. G. & Kintner, C. Rhomboid and Star facilitate presentation and processing of the Drosophila TGF-α homolog Spitz. Genes Dev. 14, 177-186 (2000). The first experimental demonstration that Star and Rhomboid-1 somehow trigger the proteolytoc release of Spitz.
-
(2000)
Genes Dev.
, vol.14
, pp. 177-186
-
-
Bang, A.G.1
Kintner, C.2
-
32
-
-
0027443215
-
Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras 1
-
Heberlein, U., Hariharan, I. K. & Rubin, G. M. Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras 1. Dev. Biol. 160, 51-63 (1993).
-
(1993)
Dev. Biol.
, vol.160
, pp. 51-63
-
-
Heberlein, U.1
Hariharan, I.K.2
Rubin, G.M.3
-
33
-
-
0033555978
-
The role of Star in the production of an activated ligand for the EGF receptor signaling pathway
-
Pickup, A. T. & Banerjee, U. The role of Star in the production of an activated ligand for the EGF receptor signaling pathway. Dev Biol. 205, 254-259 (1999).
-
(1999)
Dev Biol.
, vol.205
, pp. 254-259
-
-
Pickup, A.T.1
Banerjee, U.2
-
34
-
-
0034889139
-
Function of the Drosophila TGF-α homolog Spitz is controlled by Star and interacts directly with Star
-
Hsiung, F., Griffis, E. R., Pickup, A., Powers, M. A. & Moses, K. Function of the Drosophila TGF-α homolog Spitz is controlled by Star and interacts directly with Star. Mech. Dev. 107, 13-23 (2001).
-
(2001)
Mech. Dev.
, vol.107
, pp. 13-23
-
-
Hsiung, F.1
Griffis, E.R.2
Pickup, A.3
Powers, M.A.4
Moses, K.5
-
35
-
-
0032715588
-
Rhomboid function in the midline of the Drosophila CNS
-
Lanoue, B. R. & Jacobs, J. R. Rhomboid function in the midline of the Drosophila CNS. Dev. Genet. 25, 321-330 (1999).
-
(1999)
Dev. Genet.
, vol.25
, pp. 321-330
-
-
Lanoue, B.R.1
Jacobs, J.R.2
-
36
-
-
0031931299
-
Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis
-
Sapir, A., Schweitzer, R. & Shilo, B.-Z. Sequential activation of the EGF receptor pathway during Drosophila oogenesis establishes the dorsoventral axis. Development 125, 191-200 (1998).
-
(1998)
Development
, vol.125
, pp. 191-200
-
-
Sapir, A.1
Schweitzer, R.2
Shilo, B.-Z.3
-
37
-
-
0029015431
-
Secreted Spitz triggers the DER signalling pathway and is a limiting component in embryonic ventral ectoderm determination
-
Schweitzer, R., Shaharabany, M., Seger, R. & Shilo, B.-Z. Secreted Spitz triggers the DER signalling pathway and is a limiting component in embryonic ventral ectoderm determination, Genes Dev. 9, 1518-1529 (1995). Reported that the soluble form of Spitz was active but that the membrane-tethered form had no detectable activity, this led to the idea that proteolysis of Spitz is a key step in EGFR activation.
-
(1995)
Genes Dev.
, vol.9
, pp. 1518-1529
-
-
Schweitzer, R.1
Shaharabany, M.2
Seger, R.3
Shilo, B.-Z.4
-
38
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis controls EGF signal activation in Drosophila
-
Lee, J. R., Urban, S., Garvey, C. F. & Freeman, M. Regulated intracellular ligand transport and proteolysis controls EGF signal activation in Drosophila. Cell 107, 161-171 (2001). This paper was the first to describe the mechanism by which Star and Rhomboid-1 control the trafficking and cleavage of the TGFα-like growth factor Spitz.
-
(2001)
Cell
, vol.107
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
39
-
-
0036339998
-
Mechanism of activation of the Drosophila EGF receptor by the TGRα ligand Gurken during oogenesis
-
Ghiglione, C. et al. Mechanism of activation of the Drosophila EGF receptor by the TGRα ligand Gurken during oogenesis. Development 129, 175-186 (2002).
-
(2002)
Development
, vol.129
, pp. 175-186
-
-
Ghiglione, C.1
-
40
-
-
0037080869
-
Intracellular trafficking by Star regulates cleavage of the Drosaphila EGF receptor ligand Spitz
-
Tsruya, R. et al. Intracellular trafficking by Star regulates cleavage of the Drosaphila EGF receptor ligand Spitz. Genes Dev. 16, 222-234 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 222-234
-
-
Tsruya, R.1
-
41
-
-
0037090712
-
Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-α homologue Spitz
-
Pascall, J. C., Luck, J. E. & Brown, K. D. Expression in mammalian cell cultures reveals interdependent, but distinct, functions for Star and Rhomboid proteins in the processing of the Drosophila transforming-growth-factor-α homologue Spitz. Biochem. J. 363, 347-352 (2002).
-
(2002)
Biochem. J.
, vol.363
, pp. 347-352
-
-
Pascall, J.C.1
Luck, J.E.2
Brown, K.D.3
-
42
-
-
0034979828
-
PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and-2
-
Pellegrini, L. et al. PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and-2. J. Alzheimers Dis. 3, 181-190 (2001).
-
(2001)
J. Alzheimers Dis.
, vol.3
, pp. 181-190
-
-
Pellegrini, L.1
-
43
-
-
0031033450
-
Catalytic hydroxyl/amine dyads within serine proteases
-
Paetzel, M. & Dalbey, R. E. Catalytic hydroxyl/amine dyads within serine proteases. Trends Biochem. Sci. 22, 28-31 (1997).
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 28-31
-
-
Paetzel, M.1
Dalbey, R.E.2
-
44
-
-
0029072912
-
Structural and functional roles of asparagine 175 in the cysteine protease papain
-
Vernet, T. et al. Structural and functional roles of asparagine 175 in the cysteine protease papain. J. Biol. Chem. 270, 16645-16652(1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 16645-16652
-
-
Vernet, T.1
-
45
-
-
0034625081
-
Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease
-
Ye, J., Dave, U. P., Grishin, N. V., Goldstein, J. L. & Brown, M. S. Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease. Proc. Natl Acad. Sci. USA 97, 5123-5128 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5123-5128
-
-
Ye, J.1
Dave, U.P.2
Grishin, N.V.3
Goldstein, J.L.4
Brown, M.S.5
-
46
-
-
0033867521
-
A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch 1
-
Mumm, J. S. et al. A ligand-induced extracellular cleavage regulates γ-secretase-like proteolytic activation of Notch 1. Mol. Cell 5, 197-206 (2000).
-
(2000)
Mol. Cell
, vol.5
, pp. 197-206
-
-
Mumm, J.S.1
-
47
-
-
0033639117
-
Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins
-
Struhl, G. & Adachi, A. Requirements for presenilin-dependent cleavage of notch and other transmembrane proteins. Mol. Cell 6, 625-636 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 625-636
-
-
Struhl, G.1
Adachi, A.2
-
48
-
-
0036809216
-
Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis
-
Lemberg, M. K. & Martoglio, B. Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis. Mol. Cell 10, 735-744 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 735-744
-
-
Lemberg, M.K.1
Martoglio, B.2
-
49
-
-
0032185770
-
Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells
-
Sakai, J. et al. Molecular identification of the sterol-regulated luminal protease that cleaves SREBPs and controls lipid composition of animal cells. Mol. Cell 2, 505-514 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 505-514
-
-
Sakai, J.1
-
50
-
-
0038771224
-
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
Urban, S. & Freeman, M. Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Mol. Cell 11, 1425-1434 (2003). This paper describes the requirements within the TMD of a rhomboid substrate that make it cleavable by rhomboids. It implies that destabilization of the TMD α-helix is necessary; it also predicts that a family of Toxoplasma gondii adhesion proteins are rhomboid substrates.
-
(2003)
Mol. Cell
, vol.11
, pp. 1425-1434
-
-
Urban, S.1
Freeman, M.2
-
51
-
-
0034817498
-
Microneme proteins: Structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii
-
Soldati, D., Dubremetz, J. F. & Lebrun, M. Microneme proteins: structural and functional requirements to promote adhesion and invasion by the apicomplexan parasite Toxoplasma gondii. Int. J. Parasitol. 31, 1293-1302 (2001).
-
(2001)
Int. J. Parasitol.
, vol.31
, pp. 1293-1302
-
-
Soldati, D.1
Dubremetz, J.F.2
Lebrun, M.3
-
52
-
-
0037007235
-
Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii
-
Opitz, C. et al. Intramembrane cleavage of microneme proteins at the surface of the apicomplexan parasite Toxoplasma gondii. EMBO J. 21, 1577-1585 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 1577-1585
-
-
Opitz, C.1
-
53
-
-
0037102238
-
A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands
-
Urban, S., Lee, J. R. & Freeman, M. A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands. EMBO J. 21, 4277-4286 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 4277-4286
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
54
-
-
1242288387
-
Diverse substrate recognition mechanisms for rhomboids: Thrombomodulin is cleaved by mammalian rhomboids
-
Lohi, O., Urban, S. & Freeman, M. Diverse substrate recognition mechanisms for rhomboids: thrombomodulin is cleaved by mammalian rhomboids. Curr. Biol. 14, 263-241 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 263-241
-
-
Lohi, O.1
Urban, S.2
Freeman, M.3
-
55
-
-
0037126036
-
A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes
-
Gallio, M., Sturgill, G., Rather, P. & Kylsten, P. A conserved mechanism for extracellular signaling in eukaryotes and prokaryotes. Proc. Natl Acad. Sci. USA 99, 12208-12213 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12208-12213
-
-
Gallio, M.1
Sturgill, G.2
Rather, P.3
Kylsten, P.4
-
56
-
-
0037015265
-
Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids
-
Urban, S., Schlieper, D. & Freeman, M. Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids. Curr. Biol. 12, 1507-1512 (2002).
-
(2002)
Curr. Biol.
, vol.12
, pp. 1507-1512
-
-
Urban, S.1
Schlieper, D.2
Freeman, M.3
-
58
-
-
0027934803
-
Characterization of aarA, a pleiotrophic negative regulator of the 2′-N-aceytransferase in Providencia stuartii
-
Rather, P. N. & Orosz, E. Characterization of aarA, a pleiotrophic negative regulator of the 2′-N-aceytransferase in Providencia stuartii. J. Bacteriol. 176, 5140-5144 (1994).
-
(1994)
J. Bacteriol.
, vol.176
, pp. 5140-5144
-
-
Rather, P.N.1
Orosz, E.2
-
59
-
-
0032699221
-
Providencia stuartii genes activated by cell-to-cell signaling and identification of a gene required for production or activity of an extracellular factor
-
Rather, P. N., Ding, X., Baca-DeLancey, R. R. & Siddiqui, S. Providencia stuartii genes activated by cell-to-cell signaling and identification of a gene required for production or activity of an extracellular factor. J. Bactariol. 161, 7185-7191 (1999). References 55, 56 and 59 describe evidence that rhomboid from the bacterium Providencia stuartii controls the emission of a quorum-sensing signal. These papers provide the first evidence for shared mechanisms of intercellular signalling between bacteria and animals.
-
(1999)
J. Bactariol.
, vol.161
, pp. 7185-7191
-
-
Rather, P.N.1
Ding, X.2
Baca-DeLancey, R.R.3
Siddiqui, S.4
-
60
-
-
0034609723
-
Providencia may help find a function for a novel, widespread protein family
-
Gallio, M. & Kylsten, P. Providencia may help find a function for a novel, widespread protein family. Curr. Biol. 10, R693-R694 (2000).
-
(2000)
Curr. Biol.
, vol.10
-
-
Gallio, M.1
Kylsten, P.2
-
61
-
-
0036198860
-
Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae
-
Dimmer, K. S. et al. Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol. Biol. Cell 13, 847-853 (2002).
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 847-853
-
-
Dimmer, K.S.1
-
62
-
-
0038700756
-
Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
-
McQuibban, G. A., Saurya, S. & Freeman, M. Mitochondrial membrane remodelling regulated by a conserved rhomboid protease. Nature 423, 537-541 (2003).
-
(2003)
Nature
, vol.423
, pp. 537-541
-
-
McQuibban, G.A.1
Saurya, S.2
Freeman, M.3
-
63
-
-
0042526632
-
Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA
-
Herlan, M., Vogel, F., Bornhovd, C., Neupert, W. & Reichert, A. S. Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA. J. Biol. Chem. 278, 27781-27788 (2003). References 62 and 63 show that a mitochondrial rhomboid in yeast controls mitochondrial membrane fusion by cleaving the dynamin-like GTPase Mgm1. Reference 62 also shows that mitochondrial rhomboids are conserved in humans and other eukaryotes.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27781-27788
-
-
Herlan, M.1
Vogel, F.2
Bornhovd, C.3
Neupert, W.4
Reichert, A.S.5
-
64
-
-
0036424840
-
A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1
-
Esser, K., Tursun, B., Ingenhoven, M., Michaelis, G. & Pratje, E. A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. J. Mol. Biol. 323, 835-843 (2002). The first report of proteolysis by a mitochondrial rhomboid in yeast. In this case the substrate was cytochrome-c peroxidase.
-
(2002)
J. Mol. Biol.
, vol.323
, pp. 835-843
-
-
Esser, K.1
Tursun, B.2
Ingenhoven, M.3
Michaelis, G.4
Pratje, E.5
-
65
-
-
0033593816
-
The yeast dynamin-like protein, Mgml p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance
-
Shepard, K. A. & Yaffe, M. P. The yeast dynamin-like protein, Mgml p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance. J. Cell Biol. 144, 711-720 (1999).
-
(1999)
J. Cell Biol.
, vol.144
, pp. 711-720
-
-
Shepard, K.A.1
Yaffe, M.P.2
-
66
-
-
0034676095
-
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mirochondria
-
Wong, E. D. et al. The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mirochondria. J. Cell Biol. 151, 341-352 (2000).
-
(2000)
J. Cell Biol.
, vol.151
, pp. 341-352
-
-
Wong, E.D.1
-
67
-
-
0037415638
-
The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion
-
Wong, E. D. et al. The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J. Cell Biol. 160, 303-311 (2003).
-
(2003)
J. Cell Biol.
, vol.160
, pp. 303-311
-
-
Wong, E.D.1
-
68
-
-
0043095416
-
Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnml p-dependent manner, but remain competent for mitochondrial fusion
-
Sesaki, H., Southard, S. M., Hobbs, A. E. & Jensen, R. E. Cells lacking Pcp1p/Ugo2p, a rhomboid-like protease required for Mgm1p processing, lose mtDNA and mitochondrial structure in a Dnml p-dependent manner, but remain competent for mitochondrial fusion. Biochem. Biophys. Res. Commun. 308, 276-283 (2003).
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.308
, pp. 276-283
-
-
Sesaki, H.1
Southard, S.M.2
Hobbs, A.E.3
Jensen, R.E.4
-
69
-
-
0033772264
-
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28
-
Alexander, C. et al. OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nature Genet. 26, 211-215 (2000).
-
(2000)
Nature Genet.
, vol.26
, pp. 211-215
-
-
Alexander, C.1
-
70
-
-
0036796861
-
Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells
-
Schulz, C., Wood, C. G., Jones, D. L., Tazuke, S. I. & Fuller, M. T Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells. Development 129, 4523-4534 (2002).
-
(2002)
Development
, vol.129
, pp. 4523-4534
-
-
Schulz, C.1
Wood, C.G.2
Jones, D.L.3
Tazuke, S.I.4
Fuller, M.T.5
-
71
-
-
0036127811
-
Cloning and expression of Ventrhoid, a novel vertebrate homologue of the Drosophila EGF pathway gene rhomboid
-
Jaszai, J. & Brand, M. Cloning and expression of Ventrhoid, a novel vertebrate homologue of the Drosophila EGF pathway gene rhomboid. Mech. Dev 113, 73-77 (2002).
-
(2002)
Mech. Dev.
, vol.113
, pp. 73-77
-
-
Jaszai, J.1
Brand, M.2
-
72
-
-
0032537494
-
Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid
-
Pascall, J. C. & Brown, K. D. Characterization of a mammalian cDNA encoding a protein with high sequence similarity to the Drosophila regulatory protein Rhomboid. FEBS Lett. 429, 337-340 (1998).
-
(1998)
FEBS Lett.
, vol.429
, pp. 337-340
-
-
Pascall, J.C.1
Brown, K.D.2
-
73
-
-
0037066757
-
Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability
-
Sunnarborg, S. W. et al. Tumor necrosis factor-α converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability. J Biol. Chem, 277, 12838-12845 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12838-12845
-
-
Sunnarborg, S.W.1
-
74
-
-
0037416187
-
TACE is required for the activation of the EGFR by TGF-α in tumors
-
Borrell-Pages, M., Rojo, F., Albanell, J., Baselga, J. & Arribas, J. TACE is required for the activation of the EGFR by TGF-α in tumors. EMBO J. 22, 1114-1124 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 1114-1124
-
-
Borrell-Pages, M.1
Rojo, F.2
Albanell, J.3
Baselga, J.4
Arribas, J.5
-
75
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J. et al. An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284 (1998).
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
-
77
-
-
0014682668
-
Structure of subtilisin BPN' at 2.5 angstrom resolution
-
Wright, C. S., Alden, R. A. & Kraut, J. Structure of subtilisin BPN' at 2.5 angstrom resolution. Nature 221, 235-242 (1969).
-
(1969)
Nature
, vol.221
, pp. 235-242
-
-
Wright, C.S.1
Alden, R.A.2
Kraut, J.3
-
78
-
-
0036777494
-
Intramembrane proteolysis controls diverse signaling pathways throughout evolution
-
Urban, S. & Freeman, M. Intramembrane proteolysis controls diverse signaling pathways throughout evolution. Curr. Opin. Genet. Dev. 12, 512-518 (2002).
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 512-518
-
-
Urban, S.1
Freeman, M.2
-
79
-
-
0034681260
-
Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
-
Brown, M. S., Ye, J., Rawson, R. B. & Goldstein, J. L. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell 100, 391-398 (2000). An influential and important review that first described the phenomenon of intramembrane proteolysis; it coined the much-used term RIP for regulated intramembrane proteolysis.
-
(2000)
Cell
, vol.100
, pp. 391-398
-
-
Brown, M.S.1
Ye, J.2
Rawson, R.B.3
Goldstein, J.L.4
-
80
-
-
0037304947
-
Intramembrane cleaving proteases: Controlled liberation of proteins and bioactive peptides
-
Weihofen, A. & Martoglio, B. Intramembrane cleaving proteases: controlled liberation of proteins and bioactive peptides. Trends Cell Biol. 13, 71-78 (2003).
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 71-78
-
-
Weihofen, A.1
Martoglio, B.2
-
81
-
-
0035514568
-
Regulated intramembrane proteolysis takes another twist
-
Huppert, S. & Kopan, R. Regulated intramembrane proteolysis takes another twist. Dev. Cell 1, 590-592 (2001).
-
(2001)
Dev. Cell
, vol.1
, pp. 590-592
-
-
Huppert, S.1
Kopan, R.2
-
82
-
-
0028820299
-
Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection
-
Hua, X., Sakai, J., Ho, Y. K., Goldstein, J. L. & Brown, M. S. Hairpin orientation of sterol regulatory element-binding protein-2 in cell membranes as determined by protease protection. J. Biol Chem. 270, 29422-29427 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 29422-29427
-
-
Hua, X.1
Sakai, J.2
Ho, Y.K.3
Goldstein, J.L.4
Brown, M.S.5
-
83
-
-
0032504202
-
Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning
-
Duncan, E. A., Dave, U. P., Sakai, J., Goldstein, J. L. & Brown, M. S. Second-site cleavage in sterol regulatory element-binding protein occurs at transmembrane junction as determined by cysteine panning. J. Biol. Chem. 273, 17801-17809 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17801-17809
-
-
Duncan, E.A.1
Dave, U.P.2
Sakai, J.3
Goldstein, J.L.4
Brown, M.S.5
-
84
-
-
18444417998
-
Aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
-
Francis, R. et al. aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation. Dev. Cell 3, 85-97 (2002).
-
(2002)
Dev. Cell
, vol.3
, pp. 85-97
-
-
Francis, R.1
-
85
-
-
0034618715
-
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing
-
Yu, G. et al. Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing. Nature 407, 48-54 (2000).
-
(2000)
Nature
, vol.407
, pp. 48-54
-
-
Yu, G.1
-
86
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-Secretase complex
-
De Strooper, B. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-Secretase complex. Neuron 38, 9-12 (2003).
-
(2003)
Neuron
, vol.38
, pp. 9-12
-
-
De Strooper, B.1
-
87
-
-
0034613193
-
Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor
-
Weihofen, A., Lemberg, M. K., Ploegh, H. L., Bogyo, M. & Martoglio, B. Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor. J. Biol. Chem. 275, 30951-30956 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 30951-30956
-
-
Weihofen, A.1
Lemberg, M.K.2
Ploegh, H.L.3
Bogyo, M.4
Martoglio, B.5
-
88
-
-
0038664363
-
Reconstitution of γ-secretase activity
-
Edbauer, D. et al. Reconstitution of γ-secretase activity. Nature Cell Biol. 5, 486-488 (2003).
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 486-488
-
-
Edbauer, D.1
-
89
-
-
0035827339
-
A genomic perspective on human proteases
-
Southan, C. A genomic perspective on human proteases. FEBS Lett. 498, 214-218 (2001).
-
(2001)
FEBS Lett.
, vol.498
, pp. 214-218
-
-
Southan, C.1
-
90
-
-
0036551587
-
Secretase as a target for Alzheimer's disease
-
Wolfe, M. S. Secretase as a target for Alzheimer's disease. Curr Top. Med. Chem. 2, 371-383 (2002).
-
(2002)
Curr. Top. Med. Chem.
, vol.2
, pp. 371-383
-
-
Wolfe, M.S.1
-
91
-
-
0033599028
-
Transport-dependent proteolysis of SREBP: Relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi
-
DeBose-Boyd, R. A. et al. Transport-dependent proteolysis of SREBP: relocation of site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi. Cell 99, 703-712 (1999).
-
(1999)
Cell
, vol.99
, pp. 703-712
-
-
DeBose-Boyd, R.A.1
-
92
-
-
0033613126
-
Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
-
Nohturfft, A., DeBose-Boyd, R. A., Scheek, S., Goldstein, J. L. & Brown, M. S. Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi. Proc. Natl Acad. Sci. USA 96, 11235-11240 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 11235-11240
-
-
Nohturfft, A.1
DeBose-Boyd, R.A.2
Scheek, S.3
Goldstein, J.L.4
Brown, M.S.5
-
93
-
-
0036792050
-
Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
-
Yabe, D., Brown, M. S. & Goldstein, J. L. Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins. Proc. Natl Acad. Sci. USA 99, 12753-12758 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 12753-12758
-
-
Yabe, D.1
Brown, M.S.2
Goldstein, J.L.3
-
94
-
-
0037162719
-
Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
-
Yang, T. et al. Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell 110, 489-500 (2002).
-
(2002)
Cell
, vol.110
, pp. 489-500
-
-
Yang, T.1
-
95
-
-
0034515724
-
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
-
Ye, J. et al. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6, 1355-1364 (2000).
-
(2000)
Mol. Cell
, vol.6
, pp. 1355-1364
-
-
Ye, J.1
-
96
-
-
0033593022
-
A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors
-
Rudner, D. Z., Fawcett, P. & Losick, R. A family of membrane-embedded metalloproteases involved in regulated proteolysis of membrane-associated transcription factors. Proc. Natl Acad. Sci. USA 96, 14765-14770 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14765-14770
-
-
Rudner, D.Z.1
Fawcett, P.2
Losick, R.3
-
97
-
-
0032871073
-
Identification and characterization of a determinant (eep) on the Enterococcus faecalis chromosome that is involved in production of the peptide sex pheromone cAD1
-
An, F. Y., Sulavik, M. C. & Clewell, D. B, Identification and characterization of a determinant (eep) on the Enterococcus faecalis chromosome that is involved in production of the peptide sex pheromone cAD1. J. Bacteriol. 161, 5915-5921 (1999).
-
(1999)
J. Bacteriol.
, vol.161
, pp. 5915-5921
-
-
An, F.Y.1
Sulavik, M.C.2
Clewell, D.B.3
-
98
-
-
0036211978
-
Identification of the cAD1 sex pheromone precursor in Enterococcus faecalis
-
An, F. Y. & Clewell, D. B. Identification of the cAD1 sex pheromone precursor in Enterococcus faecalis. J. Bacteriol. 184, 1880-1887 (2002).
-
(2002)
J. Bacteriol.
, vol.184
, pp. 1880-1887
-
-
An, F.Y.1
Clewell, D.B.2
-
99
-
-
0029115555
-
The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families
-
Alzheimer's Disease Collaborative Group. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Nature Genet. 11, 219-222 (1995).
-
(1995)
Nature Genet.
, vol.11
, pp. 219-222
-
-
-
100
-
-
0036855661
-
Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer disease
-
Selkoe, D. J. Deciphering the genesis and fate of amyloid β-protein yields novel therapies for Alzheimer disease. J. Clin. Invest. 110, 1375-1381 (2002).
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 1375-1381
-
-
Selkoe, D.J.1
-
101
-
-
0033535504
-
A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain
-
De Strooper, B. et al. A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain. Nature 398, 518-522 (1999).
-
(1999)
Nature
, vol.398
, pp. 518-522
-
-
De Strooper, B.1
-
102
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl, G. & Greenwald, I. Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398, 522-525 (1999).
-
(1999)
Nature
, vol.398
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
103
-
-
0032524325
-
Nuclear access and action of notch in vivo
-
Struhl, G. & Adachi, A. Nuclear access and action of notch in vivo. Cell 93, 649-660 (1998).
-
(1998)
Cell
, vol.93
, pp. 649-660
-
-
Struhl, G.1
Adachi, A.2
-
104
-
-
0032574993
-
Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain
-
Schroeter, E. H., Kisslinger, J. A. & Kopan, R. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature 393, 382-386 (1998).
-
(1998)
Nature
, vol.393
, pp. 382-386
-
-
Schroeter, E.H.1
Kisslinger, J.A.2
Kopan, R.3
-
105
-
-
0032543565
-
Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos
-
Lecourtois, M. & Schweisguth, F. Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos. Curr. Biol. 8, 771-774 (1998).
-
(1998)
Curr. Biol.
, vol.8
, pp. 771-774
-
-
Lecourtois, M.1
Schweisguth, F.2
-
106
-
-
0141994826
-
Intramembrane-cleaving aspartic proteases and disease: Presenilins, signal peptide peptidase and their homologs
-
Martoglio, B, & Golde, T E. Intramembrane-cleaving aspartic proteases and disease: presenilins, signal peptide peptidase and their homologs. Hum. Mol. Genet. 12 (Suppl. 2), R201-R206 (2003).
-
(2003)
Hum. Mol. Genet.
, vol.12
, Issue.SUPPL. 2
-
-
Martoglio, B.1
Golde, T.E.2
-
107
-
-
0036683052
-
Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets
-
McLauchlan, J., Lemberg, M. K., Hope, G, & Martoglio, B. Intramembrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets. EMBO J. 21, 3980-3988 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 3980-3988
-
-
McLauchlan, J.1
Lemberg, M.K.2
Hope, G.3
Martoglio, B.4
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