Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA

Journal of Biological Chemistry

Volumn 278, Issue 30, 2003, Pages 27781-27788

  Herlan, Mark ^a   Vogel, Frank ^b   Bornhövd, Carsten ^a   Neupert, Walter ^a   Reichert, Andreas S ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; DNA; FISSION REACTIONS; FUSION REACTIONS; MORPHOLOGY; PROTEINS;

MITOCHONDRIA;

BIOCHEMISTRY;

AMINO ACID; DYNAMIN; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; PCP1 PROTEASE; PROTEIN MGM1; SERINE PROTEINASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; MITOCHONDRION; NONHUMAN; ORTHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

BLOTTING, WESTERN; CARBON; CARBONATES; CELL MEMBRANE; DNA, MITOCHONDRIAL; DYNAMINS; FUNGAL PROTEINS; GENETIC COMPLEMENTATION TEST; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HUMANS; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NUCLEAR PROTEINS; PHENOTYPE; PLASMIDS; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES POMBE PROTEINS;

DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0042526632     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M211311200     Document Type: Article

References (39)

1. Shaw, J. M., and Nunnari, J. (2002) Trends Cell Biol. 12, 178-184
2. Wong, E. D., Wagner, J. A., Gorsich, S. W., McCaffery, J. M., Shaw, J. M., and Nunnari, J. (2000) J. Cell Biol. 151, 341-352
3. Wong, E. D., Wagner, J. A., Scott, S. V., Okreglak, V., Holewinske, T. J., Cassidy-Stone, A., and Nunnari, J. (2003) J. Cell Biol. 160, 303-311
4. Sesaki, H., Southard, S. M., Yaffe, M. P., and Jensen, R. E. (2003) Mol. Biol. Cell, in press
5. Reichert, A. S., and Neupert, W. (2002) Biochim. Biophys. Acta 1592, 41-49
6. Sesaki, H., and Jensen, R. E. (1999) J. Cell Biol. 147, 699-706
7. Westermann, B. (2002) EMBO Rep. 3, 527-531
8. Fritz, S., Rapaport, D., Klanner, E., Neupert, W., and Westermann, B. (2001) J. Cell Biol. 152, 683-692
9. Bleazard, W., McCaffery, J. M., King, E. J., Bale, S., Mozdy, A., Tieu, Q., Nunnari, J., and Shaw, J. M. (1999) Nat. Cell. Biol. 1, 298-304
10. Guan, K., Farh, L., Marshall, T. K., and Deschenes, R. J. (1993) Curr. Genet. 24, 141-148
11. Jones, B. A., and Fangman, W. L. (1992) Genes Dev. 6, 380-389
12. Shepard, K. A., and Yaffe, M. P. (1999) J. Cell Biol. 144, 711-720
13. Delettre, C., Lenaers, G., Pelloquin, L., Belenguer, P., and Hamel, C. P. (2002) Mol. Genet. Metab. 75, 97-107
14. Hinshaw, J. E. (2000) Annu. Rev. Cell Dev. Biol. 16, 483-519
15. Olichon, A., Baricault, L., Gas, N., Guillou, E., Valette, A., Belenguer, P., and Lenaers, G. (2003) J. Biol. Chem. 278, 7743-7746
16. Pelloquin, L., Belenguer, P., Menon, Y., Gas, N., and Ducommun, B. (1999) J. Cell Sci. 112, 4151-4161
17. Olichon, A., Emorine, L. J., Descoins, E., Pelloquin, L., Brichese, L., Gas, N., Guillou, E., Delettre, C., Valette, A., Hamel, C. P., Ducommun, B., Lenaers, G., and Belenguer, P. (2002) FEBS Lett. 523, 171-176
18. Misaka, T., Miyashita, T., and Kubo, Y. (2002) J. Biol. Chem. 277, 15834-15842
19. Pelloquin, L., Belenguer, P., Menon, Y., and Ducommun, B. (1998) Biochem. Biophys. Res. Commun. 251, 720-726
20. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 61-68
21. Guthrie, C., and Fink, G. R. (1991) Methods Enzymol. 194, 1-270
22. Sherman, F. F., Fink, G. R., and Hicks, J. (1986) Methods in Yeast Genetics: A Laboratory Course, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
23. Sirrenberg, C., Bauer, M. F., Guiard, B., Neupert, W., and Brunner, M. (1996) Nature 384, 582-585
24. Westermann, B., and Neupert, W. (2000) Yeast 16, 1421-1427
25. Prokisch, H., Neupert, W., and Westermann, B. (2000) Mol. Biol. Cell 11, 2961-2971
26. Herrmann, J. M., Neupert, W., and Stuart, R. A. (1997) EMBO J. 16, 2217-2226
27. Pfanner, N., and Neupert, W. (1987) J. Biol. Chem. 262, 7528-7536
28. Neupert, W. (1997) Annu. Rev. Biochem. 66, 863-917
29. Rojo, E. E., Guiard, B., Neupert, W., and Stuart, R. A. (1998) J. Biol. Chem. 273, 8040-8047
30. Sweitzer, S. M., and Hinshaw, J. E. (1998) Cell 93, 1021-1029
31. Steinmetz, L. M., Scharfe, C., Deutschbauer, A. M., Mokranjac, D., Herman, Z. S., Jones, T., Chu, A. M., Giaever, G., Prokisch, H., Oefner, P. J., and Davis, R. W. (2002) Nat. Genet. 31, 400-404
32. Dimmer, K. S., Fritz, S., Fuchs, F., Messerschmitt, M., Weinbach, N., Neupert, W., and Westermann, B. (2002) Mol. Biol. Cell 13, 847-853
33. Wasserman, J. D., Urban, S., and Freeman, M. (2000) Genes Dev. 14, 1651-1663
34. Esser, K., Tursun, B., Ingenhoven, M., Michaelis, G., and Pratje, E. (2002) J. Mol. Biol. 323, 835-843
35. Stuart, R. A., Gruhler, A., van der Klei, I., Guiard, B., Koll, H., and Neupert, W. (1994) Eur. J. Biochem. 220, 9-18
36. Reid, G. A., Yonetani, T., and Schatz, G. (1982) J. Biol. Chem. 257, 13068-13074
37. Daum, G., Bohni, P. C., and Schatz, G. (1982) J. Biol. Chem. 257, 13028-13033
38. Arnold, I., and Langer, T. (2002) Biochim. Biophys. Acta 1592, 89-96
39. Urban, S., Schlieper, D., and Freeman, M. (2002) Curr. Biol. 12, 1507-1512