-
1
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr, J. F., Wyllie, A. H., and Currie, A. R. 1972. Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26:239-247.
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-247
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
0019225636
-
Cell death: The significance of apoptosis
-
Wyllie, A. H., Kerr, J. F. R., and Currie, A. R. 1980. Cell death: The significance of apoptosis. Intl. Rev. Cytol. 68:251-306.
-
(1980)
Intl. Rev. Cytol.
, vol.68
, pp. 251-306
-
-
Wyllie, A.H.1
Kerr, J.F.R.2
Currie, A.R.3
-
3
-
-
0032055973
-
Neuronal cell death
-
Pettmann, B. and Henderson, C. E. 1998. Neuronal cell death. Neuron 20:633-647.
-
(1998)
Neuron
, vol.20
, pp. 633-647
-
-
Pettmann, B.1
Henderson, C.E.2
-
4
-
-
0032999788
-
Poly (ADP-ribose) polymerase, nitric oxide and cell death
-
Peiper, A. A., Verma, A., Zhang, J., and Snyder, S. H. 1999. Poly (ADP-ribose) polymerase, nitric oxide and cell death. TiPS 20:171-181.
-
(1999)
TiPS
, vol.20
, pp. 171-181
-
-
Peiper, A.A.1
Verma, A.2
Zhang, J.3
Snyder, S.H.4
-
5
-
-
0033956278
-
Calpain and caspase: Can you tell the difference?
-
Wang, K. K. W. 2000. Calpain and caspase: Can you tell the difference? TiNS 23:20-26.
-
(2000)
TiNS
, vol.23
, pp. 20-26
-
-
Wang, K.K.W.1
-
6
-
-
0035575679
-
Programmed cell death: Alive and well in the new millennium
-
Kaufmann, S. H. and Hengartner, M. O. 2001 Programmed cell death: Alive and well in the new millennium. Trends Cell Biol. 11:526-534.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 526-534
-
-
Kaufmann, S.H.1
Hengartner, M.O.2
-
7
-
-
0032505127
-
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
-
Juo, P., Kuo, C. J., Yuan, J., and Blenis, J. 1998. Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade. Curr. Biol. 8:1001-1008.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1001-1008
-
-
Juo, P.1
Kuo, C.J.2
Yuan, J.3
Blenis, J.4
-
8
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu, X., Kim, C. N., Yang, J., Jemmerson, R., and Wang, X. 1996. Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c. Cell 86:147-157.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
9
-
-
0029950290
-
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease
-
Susin, S. A., Zamzami, N., Castedo, M., Hirsch, T., Marchetti, P., Macho, A., Daugas, E., Geuskens, M., and Kroemer, G. 1996. Bcl-2 inhibits the mitochondrial release of an apoptogenic protease. J. Exp. Med. 184:1331-1341.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1331-1341
-
-
Susin, S.A.1
Zamzami, N.2
Castedo, M.3
Hirsch, T.4
Marchetti, P.5
Macho, A.6
Daugas, E.7
Geuskens, M.8
Kroemer, G.9
-
11
-
-
0038719671
-
JNK-dependent release of mitochondrial protein, SMAC during apoptosis in multiple myeloma (MM) cells
-
Mar 28 epub ahead of print
-
Chauhan, D., Li, G., Hideshima, T., Podar, K., Mitsiades, C., Mitsiades, N., Munshi, N., Kharbanda, S., and Anderson, K. C. 2003. JNK-dependent release of mitochondrial protein, SMAC during apoptosis in multiple myeloma (MM) cells. J. Biol. Chem. (Mar 28 epub ahead of print).
-
(2003)
J. Biol. Chem.
-
-
Chauhan, D.1
Li, G.2
Hideshima, T.3
Podar, K.4
Mitsiades, C.5
Mitsiades, N.6
Munshi, N.7
Kharbanda, S.8
Anderson, K.C.9
-
12
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. 1997. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
13
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li, H., Zhu, H., Xu, C. J., and Yuan, J. 1998. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 94:491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
14
-
-
0033083559
-
Neuronal cell death: A demise with different shapes
-
Nicotera, P., Leist, M., and Manzo, L. 1999. Neuronal cell death: A demise with different shapes. TiPS 20:46-51.
-
(1999)
TiPS
, vol.20
, pp. 46-51
-
-
Nicotera, P.1
Leist, M.2
Manzo, L.3
-
15
-
-
0030738366
-
Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis
-
Bonetti, B. and Raine, C. S. 1997. Multiple sclerosis: Oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis. Ann. Neurol. 42:74-84.
-
(1997)
Ann. Neurol.
, vol.42
, pp. 74-84
-
-
Bonetti, B.1
Raine, C.S.2
-
16
-
-
0345647098
-
Glutamate neurotoxicity in mouse cortical neurons: Atypical necrosis with DNA ladders and chromatin condensation
-
Sohn, S., Kim, E. Y., and Gwag, B. J. 1998. Glutamate neurotoxicity in mouse cortical neurons: Atypical necrosis with DNA ladders and chromatin condensation. Neurosci. Lett. 240:147-150.
-
(1998)
Neurosci. Lett.
, vol.240
, pp. 147-150
-
-
Sohn, S.1
Kim, E.Y.2
Gwag, B.J.3
-
17
-
-
0031816414
-
Apoptosis, excitotoxicity, and neuropathology
-
Leist, M. and Nicotera, P. 1998. Apoptosis, excitotoxicity, and neuropathology. Exp. Cell Res. 239:183-201.
-
(1998)
Exp. Cell Res.
, vol.239
, pp. 183-201
-
-
Leist, M.1
Nicotera, P.2
-
18
-
-
0021926813
-
Macrophage recognition of cells undergoing programmed cell death (apoptosis)
-
Duvall, E., Wyllie, A. H., and Morris, R. G. 1985. Macrophage recognition of cells undergoing programmed cell death (apoptosis). Immunology 56:351-358.
-
(1985)
Immunology
, vol.56
, pp. 351-358
-
-
Duvall, E.1
Wyllie, A.H.2
Morris, R.G.3
-
19
-
-
0034074468
-
Energy requirement for caspase activation and neuronal cell death
-
Nicotera, P., Leist, M., Fava, E., Berliocchi, L., and Volbracht, C. 2000. Energy requirement for caspase activation and neuronal cell death. Brain Pathol. 10:276-282.
-
(2000)
Brain Pathol.
, vol.10
, pp. 276-282
-
-
Nicotera, P.1
Leist, M.2
Fava, E.3
Berliocchi, L.4
Volbracht, C.5
-
20
-
-
0025265926
-
The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
-
Choi, D. W. and Rothman, S. M. 1990. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Ann. Rev. Neurosci. 13:171-182.
-
(1990)
Ann. Rev. Neurosci.
, vol.13
, pp. 171-182
-
-
Choi, D.W.1
Rothman, S.M.2
-
21
-
-
0028924890
-
Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis
-
Nitatori, T., Sato, N., Waguri, S., Karasawa, Y., Araki, H., Shibanai, K., Kominami, E., and Uchiyama, Y. 1995. Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis. J. Neurosci. 15:1001-1011.
-
(1995)
J. Neurosci.
, vol.15
, pp. 1001-1011
-
-
Nitatori, T.1
Sato, N.2
Waguri, S.3
Karasawa, Y.4
Araki, H.5
Shibanai, K.6
Kominami, E.7
Uchiyama, Y.8
-
22
-
-
0030273118
-
Neurobiology of disease
-
Choi, D. W. 1996. Neurobiology of disease. Curr. Opin. Neurobiol. 6:667-672.
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 667-672
-
-
Choi, D.W.1
-
23
-
-
0029153913
-
Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures
-
Bonfoco, E., Krainc, D., Ankarcrona, M., Nicotera, P., and Lipton, S. A. 1995. Apoptosis and necrosis: Two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc. Natl. Acad. Sci. USA 92:7162-7166.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7162-7166
-
-
Bonfoco, E.1
Krainc, D.2
Ankarcrona, M.3
Nicotera, P.4
Lipton, S.A.5
-
25
-
-
0023767261
-
Non-competitive antagonists of N-methyl-D-aspartate receptors protect cortical and hippocampal cell cultures against glutamate neurotoxicity
-
Rondouin, G., Drian, M. J., Chicheportiche, R., Kamenka, J. M., and Privat, A. 1998. Non-competitive antagonists of N-methyl-D-aspartate receptors protect cortical and hippocampal cell cultures against glutamate neurotoxicity. Neurosci. Lett. 91:199-203.
-
(1998)
Neurosci. Lett.
, vol.91
, pp. 199-203
-
-
Rondouin, G.1
Drian, M.J.2
Chicheportiche, R.3
Kamenka, J.M.4
Privat, A.5
-
26
-
-
0023109409
-
Glutamate neurotoxicity in cortical cell culture
-
Choi, D. W., Maulucci-Gedde, M., and Kriegstein, A. R. 1987. Glutamate neurotoxicity in cortical cell culture. J. Neurosci. 7:357-368.
-
(1987)
J. Neurosci.
, vol.7
, pp. 357-368
-
-
Choi, D.W.1
Maulucci-Gedde, M.2
Kriegstein, A.R.3
-
27
-
-
0029827804
-
Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells
-
Budd, S. L. and Nicholls, D. G. 1996. Mitochondria, calcium regulation, and acute glutamate excitotoxicity in cultured cerebellar granule cells. J. Neurochem. 67:2282-2291.
-
(1996)
J. Neurochem.
, vol.67
, pp. 2282-2291
-
-
Budd, S.L.1
Nicholls, D.G.2
-
28
-
-
0033763403
-
Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate
-
Slagsvold, H. H., Marvik, O. J., Eidem, G., Kristoffersen, N., and Paulsen, R. E. 2000. Detection of high molecular weight DNA fragments characteristic of early stage apoptosis in cerebellar granule cells exposed to glutamate. Exp. Brain Res. 135:173-178.
-
(2000)
Exp. Brain Res.
, vol.135
, pp. 173-178
-
-
Slagsvold, H.H.1
Marvik, O.J.2
Eidem, G.3
Kristoffersen, N.4
Paulsen, R.E.5
-
29
-
-
0031041530
-
Slowly triggered excitotoxicity occurs by necrosis in cortical cultures
-
Gwag, B. J., Koh, J. Y., DeMaro, J. A., Ying, H. S., Jacquin, M., and Choi, D. W. 1997. Slowly triggered excitotoxicity occurs by necrosis in cortical cultures. Neuroscience 77:393-401.
-
(1997)
Neuroscience
, vol.77
, pp. 393-401
-
-
Gwag, B.J.1
Koh, J.Y.2
DeMaro, J.A.3
Ying, H.S.4
Jacquin, M.5
Choi, D.W.6
-
30
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona, M., Dypbukt, J. M., Bonfoco, E., Zhivotovsky, B., Orrenius, S., Lipton, S. A., and Nicotera, P. 1995. Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function. Neuron 15:961-973.
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotera, P.7
-
31
-
-
0036524672
-
Characterization of the cell death modes and the associated changes in cellular energy supply in response to AIPcS4-PDT
-
Plaetzer, K., Kiesslich, T., Krammer, B., and Hammerl, P. 2002. Characterization of the cell death modes and the associated changes in cellular energy supply in response to AIPcS4-PDT. Photochem. Photobiol. Sci. 1:172-177.
-
(2002)
Photochem. Photobiol. Sci.
, vol.1
, pp. 172-177
-
-
Plaetzer, K.1
Kiesslich, T.2
Krammer, B.3
Hammerl, P.4
-
32
-
-
0030900980
-
Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
-
Leist, M., Single, B., Castoldi, A. F., Kuhnle, S., and Nicotera, P. 1997. Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis. J. Exp. Med. 185:1481-1486.
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1481-1486
-
-
Leist, M.1
Single, B.2
Castoldi, A.F.3
Kuhnle, S.4
Nicotera, P.5
-
33
-
-
85047695605
-
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside
-
Grusch, M., Polgar, D., Gfatter, S., Leuhuber, K., Huettenbrenner, S., Leisser, C., Fuhrmann, G., Kassie, F., Steinkellner, H., Smid, K., Peters, G. J., Jayaram, H. N., Klopal, W., Szekeres, T., Knasmuller, S., and Krupitza, G. 2002. Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside. Cell. Death Differ. 9:169-178.
-
(2002)
Cell. Death Differ.
, vol.9
, pp. 169-178
-
-
Grusch, M.1
Polgar, D.2
Gfatter, S.3
Leuhuber, K.4
Huettenbrenner, S.5
Leisser, C.6
Fuhrmann, G.7
Kassie, F.8
Steinkellner, H.9
Smid, K.10
Peters, G.J.11
Jayaram, H.N.12
Klopal, W.13
Szekeres, T.14
Knasmuller, S.15
Krupitza, G.16
-
34
-
-
0032704329
-
Tributyltin-induced apoptosis requires glycolytic adenosine trisphosphate production
-
Stridh, H., Fava, E., Single, B., Nicotera, P., Orrenius, S., and Leist, M. 1999. Tributyltin-induced apoptosis requires glycolytic adenosine trisphosphate production. Chem. Res. Toxicol. 12:874-882.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 874-882
-
-
Stridh, H.1
Fava, E.2
Single, B.3
Nicotera, P.4
Orrenius, S.5
Leist, M.6
-
35
-
-
0037308233
-
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes
-
Kim, J. S., Qian, T., and Lemasters, J. J. 2003. Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes. Gastroenterology 124:494-503.
-
(2003)
Gastroenterology
, vol.124
, pp. 494-503
-
-
Kim, J.S.1
Qian, T.2
Lemasters, J.J.3
-
36
-
-
0033822094
-
D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons
-
Delgado-Esteban, M., Almeida, A., and Bolanos, J. P. 2000. D-Glucose prevents glutathione oxidation and mitochondrial damage after glutamate receptor stimulation in rat cortical primary neurons. J. Neurochem. 75:1618-1624.
-
(2000)
J. Neurochem.
, vol.75
, pp. 1618-1624
-
-
Delgado-Esteban, M.1
Almeida, A.2
Bolanos, J.P.3
-
37
-
-
0034705057
-
Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons
-
Budd, S. L., Tenneti, L., Lishnak, T., and Lipton, S. A. 2000. Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons. Proc. Natl. Acad. Sci. USA 97:6161-6166.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6161-6166
-
-
Budd, S.L.1
Tenneti, L.2
Lishnak, T.3
Lipton, S.A.4
-
38
-
-
0034864018
-
Mitochondrial involvement in brain function and dysfunction: Relevance to aging, neurodegenerative disorders and longevity
-
Calabrese, V., Scapagnini, G., Giuffrida Stella, A. M., Bates, T. E., and Clark, J. B. 2001. Mitochondrial involvement in brain function and dysfunction: Relevance to aging, neurodegenerative disorders and longevity. Neurochem. Res. 26:739-764.
-
(2001)
Neurochem. Res.
, vol.26
, pp. 739-764
-
-
Calabrese, V.1
Scapagnini, G.2
Giuffrida Stella, A.M.3
Bates, T.E.4
Clark, J.B.5
-
39
-
-
0023851503
-
Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
-
Martin, D. P., Schmidt, R. E., DiStefano, P. S., Lowry, O. H., Carter, J. G., and Johnson, E. M. Jr. 1988. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol. 106:829-844.
-
(1988)
J. Cell Biol.
, vol.106
, pp. 829-844
-
-
Martin, D.P.1
Schmidt, R.E.2
DiStefano, P.S.3
Lowry, O.H.4
Carter, J.G.5
Johnson Jr., E.M.6
-
40
-
-
0031972678
-
Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons
-
Watson, A., Eilers, A., Lallemand, D., Kyriakis, J., Rubin, L. L., and Ham, J. 1998. Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons. J. Neurosci. 18:751-762.
-
(1998)
J. Neurosci.
, vol.18
, pp. 751-762
-
-
Watson, A.1
Eilers, A.2
Lallemand, D.3
Kyriakis, J.4
Rubin, L.L.5
Ham, J.6
-
41
-
-
0027483920
-
Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP
-
D'Mello, S. R., Galli, C., Ciotti, T., and Calissano, P. 1993. Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor I and cAMP. Proc. Natl. Acad. Sci. USA 90:10989-10993.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10989-10993
-
-
D'Mello, S.R.1
Galli, C.2
Ciotti, T.3
Calissano, P.4
-
42
-
-
0037032594
-
Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death
-
Hong, H. N., Yoon, S. Y., Suh, J., Lee, J. H., and Kim, D. 2002. Differential activation of caspase-3 at two maturational stages during okadaic acid-induced rat neuronal death. Neurosci. Lett. 334:63-67.
-
(2002)
Neurosci. Lett.
, vol.334
, pp. 63-67
-
-
Hong, H.N.1
Yoon, S.Y.2
Suh, J.3
Lee, J.H.4
Kim, D.5
-
43
-
-
0036724767
-
Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death
-
McCollum, A. T., Nasr, P., and Estus, S. 2002. Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death. J. Neurochem. 82:1208-1220.
-
(2002)
J. Neurochem.
, vol.82
, pp. 1208-1220
-
-
McCollum, A.T.1
Nasr, P.2
Estus, S.3
-
44
-
-
0036859738
-
Defining characteristics of types I and II apoptotic cells in response to TRAIL
-
Özören, N. and El-Deiry, W. S. 2002. Defining characteristics of types I and II apoptotic cells in response to TRAIL. Neoplasia 4:551-557.
-
(2002)
Neoplasia
, vol.4
, pp. 551-557
-
-
Özören, N.1
El-Deiry, W.S.2
-
45
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu, Y., Benedict, M. A., Ding, L., and Núñez, G. 1999. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J. 18:3586-3595.
-
(1999)
EMBO J.
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Núñez, G.4
-
46
-
-
0026582672
-
Ribonucleotide reductase: Regulation, regulation, regulation
-
Elledge, S. J., Zhou, Z., and Allen, J. B. 1992. Ribonucleotide reductase: Regulation, regulation, regulation. Trends Biochem. Sci. 17:119-123.
-
(1992)
Trends Biochem. Sci.
, vol.17
, pp. 119-123
-
-
Elledge, S.J.1
Zhou, Z.2
Allen, J.B.3
-
47
-
-
0033547430
-
p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxide
-
Brockhaus, F. and Brune, B. 1999. p53 accumulation in apoptotic macrophages is an energy demanding process that precedes cytochrome c release in response to nitric oxide. Oncogene 18:6403-6410.
-
(1999)
Oncogene
, vol.18
, pp. 6403-6410
-
-
Brockhaus, F.1
Brune, B.2
-
48
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du, C., Fang, M., Li, Y., Li, L., and Wang, X. 2000. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102:33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
49
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
Hegde, R., Srinivasula, S. M., Zhang, Z., Wassell, R., Mukattash, R., Cilenti, L., DuBois, G., Lazebnik, Y., Zervos, A. S., Fernandes-Alnemri, T., and Alnemri, E. S. 2002. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. J. Biol. Chem. 277:432-438.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 432-438
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.3
Wassell, R.4
Mukattash, R.5
Cilenti, L.6
DuBois, G.7
Lazebnik, Y.8
Zervos, A.S.9
Fernandes-Alnemri, T.10
Alnemri, E.S.11
-
50
-
-
0037016707
-
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
-
Martins, L. M., Iaccarino, I., Tenev, T., Gschmeissner, S., Totty, N. F., Lemoine, N. R., Savopoulos, J., Gray, C. W., Creasy, C. L., Dingwall, C., and Downward, J. 2002. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J. Biol. Chem. 277:439-444.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 439-444
-
-
Martins, L.M.1
Iaccarino, I.2
Tenev, T.3
Gschmeissner, S.4
Totty, N.F.5
Lemoine, N.R.6
Savopoulos, J.7
Gray, C.W.8
Creasy, C.L.9
Dingwall, C.10
Downward, J.11
-
51
-
-
0037016686
-
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
-
Verhagen, A. M., Silke, J., Ekert, P. G., Pakusch, M., Kaufmann, H., Connolly, L. M., Day, C. L., Tikoo, A., Burke, R., Wrobel, C., Moritz, R. L., Simpson, R. J., and Vaux, D. L. 2002. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. J. Biol. Chem. 277:445-454.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 445-454
-
-
Verhagen, A.M.1
Silke, J.2
Ekert, P.G.3
Pakusch, M.4
Kaufmann, H.5
Connolly, L.M.6
Day, C.L.7
Tikoo, A.8
Burke, R.9
Wrobel, C.10
Moritz, R.L.11
Simpson, R.J.12
Vaux, D.L.13
-
52
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li, L. Y., Luo, X., and Wang, X. 2001. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412:95-99.
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
53
-
-
0035811511
-
Mitochondrial endonuclease G is important for apoptosis in C. elegans
-
Parrish, J., Li, L., Klotz, K., Ledwich, D., Wang, X., and Xue, D. 2001. Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature 412:90-94.
-
(2001)
Nature
, vol.412
, pp. 90-94
-
-
Parrish, J.1
Li, L.2
Klotz, K.3
Ledwich, D.4
Wang, X.5
Xue, D.6
-
54
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., Larochette, N., Goodlett, D. R., Aebersold, R., Siderovski, D. P., Penninger, J. M., and Kroemer, G. 1999. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397:441-446.
-
(1999)
Nature
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
Marzo, I.4
Snow, B.E.5
Brothers, G.M.6
Mangion, J.7
Jacotot, E.8
Costantini, P.9
Loeffler, M.10
Larochette, N.11
Goodlett, D.R.12
Aebersold, R.13
Siderovski, D.P.14
Penninger, J.M.15
Kroemer, G.16
-
55
-
-
18244387009
-
Pre-processed caspase-9 contained in mitochondria participates in apoptosis
-
Costantini, P., Bruey, J. M., Castedo, M., Metivier, D., Loeffler, M., Susin, S. A., Ravagnan, L., Zamzami, N., Garrido, C., and Kroemer, G. 2002. Pre-processed caspase-9 contained in mitochondria participates in apoptosis. Cell. Death Differ. 9:82-88.
-
(2002)
Cell. Death Differ.
, vol.9
, pp. 82-88
-
-
Costantini, P.1
Bruey, J.M.2
Castedo, M.3
Metivier, D.4
Loeffler, M.5
Susin, S.A.6
Ravagnan, L.7
Zamzami, N.8
Garrido, C.9
Kroemer, G.10
-
56
-
-
13044305983
-
Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia
-
Krajewski, S., Krajewska, M., Ellerby, L. M., Welsh, K., Xie, Z., Deveraux, Q. L., Salvosen, G. S., Bredesen, D. E., Rosonthal, R. E., and Reed, J. C. 1999. Release of caspase-9 from mitochondria during neuronal apoptosis and cerebral ischemia. Proc. Natl. Acad. Sci. USA 96:5752-5757.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5752-5757
-
-
Krajewski, S.1
Krajewska, M.2
Ellerby, L.M.3
Welsh, K.4
Xie, Z.5
Deveraux, Q.L.6
Salvosen, G.S.7
Bredesen, D.E.8
Rosonthal, R.E.9
Reed, J.C.10
-
57
-
-
0036848165
-
Caspases are not localized in mitochondria during life or death
-
van Loo, G., Saelens, X., Matthijssens, F., Schotte, P., Beyaert, R., Declercq, W., and Vandenabeele, P. 2002. Caspases are not localized in mitochondria during life or death. Cell. Death Differ. 9:1207-1211.
-
(2002)
Cell. Death Differ.
, vol.9
, pp. 1207-1211
-
-
Van Loo, G.1
Saelens, X.2
Matthijssens, F.3
Schotte, P.4
Beyaert, R.5
Declercq, W.6
Vandenabeele, P.7
-
58
-
-
0030610962
-
Role for Bcl-xL as an inhibitor of cytosolic cytochrome c accumulation in DNA damage-induced apoptosis
-
Kharbanda, S., Pandey, P., Schofield, L., Israels, S., Roncinske, R., Yoshida, K., Bharti, A., Yuan, Z. M., Saxena, S., Weichselbaum, R., Nalin, C., and Kufe, D. 1997. Role for Bcl-xL as an inhibitor of cytosolic cytochrome c accumulation in DNA damage-induced apoptosis. Proc. Natl. Acad. Sci. USA 94:6939-6942.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6939-6942
-
-
Kharbanda, S.1
Pandey, P.2
Schofield, L.3
Israels, S.4
Roncinske, R.5
Yoshida, K.6
Bharti, A.7
Yuan, Z.M.8
Saxena, S.9
Weichselbaum, R.10
Nalin, C.11
Kufe, D.12
-
59
-
-
0030843575
-
Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis
-
Kim, C. N., Wang, X., Huang, Y., Ibrado, A. M., Liu, L., Fang, G., and Bhalla, K. 1997. Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis. Cancer Res. 57:3115-3120.
-
(1997)
Cancer Res.
, vol.57
, pp. 3115-3120
-
-
Kim, C.N.1
Wang, X.2
Huang, Y.3
Ibrado, A.M.4
Liu, L.5
Fang, G.6
Bhalla, K.7
-
60
-
-
0030741528
-
Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system
-
Kluck, R. M., Martin, S. J., Hoffman, B. M., Zhou, J. S., Green, D. R., and Newmeyer, D. D. 1997. Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system. EMBO J. 16:4639-4649.
-
(1997)
EMBO J.
, vol.16
, pp. 4639-4649
-
-
Kluck, R.M.1
Martin, S.J.2
Hoffman, B.M.3
Zhou, J.S.4
Green, D.R.5
Newmeyer, D.D.6
-
61
-
-
0037184910
-
Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis
-
Martin, A. G. and Fearnhead, H. O. 2002. Apocytochrome c blocks caspase-9 activation and Bax-induced apoptosis. J. Biol. Chem. 277:50834-50841.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 50834-50841
-
-
Martin, A.G.1
Fearnhead, H.O.2
-
62
-
-
0031036872
-
Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
-
Yang, J., Liu, X., Bhalla, K., Kim, C. N., Ibrado, A. M., Cai, J., Peng, T., Jones, D. P., and Wang, X. 1997. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275:1129-1132.
-
(1997)
Science
, vol.275
, pp. 1129-1132
-
-
Yang, J.1
Liu, X.2
Bhalla, K.3
Kim, C.N.4
Ibrado, A.M.5
Cai, J.6
Peng, T.7
Jones, D.P.8
Wang, X.9
-
63
-
-
0031973203
-
Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts
-
Hampton, M. B., Zhivotovsky, B., Slater, A. F., Burgess, D. H., and Orrenius, S. 1998. Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts. Biochem. J. 329:95-99.
-
(1998)
Biochem. J.
, vol.329
, pp. 95-99
-
-
Hampton, M.B.1
Zhivotovsky, B.2
Slater, A.F.3
Burgess, D.H.4
Orrenius, S.5
-
64
-
-
0034710942
-
Cytochrome c binding to Apaf-1: The effects of dATP and ionic strength
-
Purring-Koch, C. and McLendon, G. 2000 Cytochrome c binding to Apaf-1: The effects of dATP and ionic strength. Proc. Natl. Acad. Sci. USA 97:11928-11931.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11928-11931
-
-
Purring-Koch, C.1
McLendon, G.2
-
65
-
-
0036723818
-
Cytochrome c release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis: Lack of mitochondrial swelling
-
Wigdal, S. S., Kirkland, R. A., Franklin, J. L., and Haak-Frendscho, M. 2002. Cytochrome c release precedes mitochondrial membrane potential loss in cerebellar granule neuron apoptosis: Lack of mitochondrial swelling. J. Neurochem. 82:1029-1038.
-
(2002)
J. Neurochem.
, vol.82
, pp. 1029-1038
-
-
Wigdal, S.S.1
Kirkland, R.A.2
Franklin, J.L.3
Haak-Frendscho, M.4
-
66
-
-
0034631832
-
Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization
-
150.1.131
-
Deshmukh, D., Kuida, K., and Johnson, E. M. Jr. 2000. Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization. J. Cell. Biol. 150.1.131.
-
(2000)
J. Cell. Biol.
-
-
Deshmukh, D.1
Kuida, K.2
Johnson Jr., E.M.3
-
67
-
-
0037119178
-
N-Methyl-D-aspartate receptor and L-type voltage-gated Ca(2+) channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia
-
Zhang, C., Shen, W., and Zhang, G. 2002. N-Methyl-D-aspartate receptor and L-type voltage-gated Ca(2+) channel antagonists suppress the release of cytochrome c and the expression of procaspase-3 in rat hippocampus after global brain ischemia. Neurosci. Lett. 328:265-268.
-
(2002)
Neurosci. Lett.
, vol.328
, pp. 265-268
-
-
Zhang, C.1
Shen, W.2
Zhang, G.3
-
68
-
-
0038587580
-
Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity
-
Zhao, H., Yenari, M. A., Cheng, D., Sapolsky, R. M., and Steinberg, G. K. 2003. Bcl-2 overexpression protects against neuron loss within the ischemic margin following experimental stroke and inhibits cytochrome c translocation and caspase-3 activity. J. Neurochem. 85:1026-1028.
-
(2003)
J. Neurochem.
, vol.85
, pp. 1026-1028
-
-
Zhao, H.1
Yenari, M.A.2
Cheng, D.3
Sapolsky, R.M.4
Steinberg, G.K.5
-
69
-
-
0036048873
-
Cytochrome c and caspase-9 expression in Huntington's disease
-
Kiechle, T., Dedeoglu, A., Kubilus, J., Kowall, N. W., Beal, M. F., Friedlander, R., Hersch, S. M., and Ferrante, R. J. 2002. Cytochrome c and caspase-9 expression in Huntington's disease. Neuromol. Med. 1:183-195.
-
(2002)
Neuromol. Med.
, vol.1
, pp. 183-195
-
-
Kiechle, T.1
Dedeoglu, A.2
Kubilus, J.3
Kowall, N.W.4
Beal, M.F.5
Friedlander, R.6
Hersch, S.M.7
Ferrante, R.J.8
-
70
-
-
0035078404
-
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor
-
Loeffler, M., Daugas, E., Susin, S. A., Zamzami, N., Metivier, D., Nieminen, A. L., Brothers, G., Penninger, J. M., and Kroemer, G. 2001. Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor. FASEB J. 15:758-767.
-
(2001)
FASEB J.
, vol.15
, pp. 758-767
-
-
Loeffler, M.1
Daugas, E.2
Susin, S.A.3
Zamzami, N.4
Metivier, D.5
Nieminen, A.L.6
Brothers, G.7
Penninger, J.M.8
Kroemer, G.9
-
71
-
-
0035890012
-
Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus
-
Braun, J. S., Novak, R., Murray, P. J., Eischen, C. M., Susin, S. A., Kroemer, G., Halle, A., Weber, J. R., Tuomanen, E. I., and Cleveland, J. L. 2001. Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus. J. Infect. Dis. 184:1300-1309.
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 1300-1309
-
-
Braun, J.S.1
Novak, R.2
Murray, P.J.3
Eischen, C.M.4
Susin, S.A.5
Kroemer, G.6
Halle, A.7
Weber, J.R.8
Tuomanen, E.I.9
Cleveland, J.L.10
-
72
-
-
0036323443
-
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death
-
Cregan, S. P., Fortin, A., MacLaurin, J. G., Callaghan, S. M., Cecconi, F., Yu, S. W., Dawson, T. M., Dawson, V. L., Park, D. S., Kroemer, G., and Slack, R. S. 2002. Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J. Cell. Biol. 158:507-517.
-
(2002)
J. Cell. Biol.
, vol.158
, pp. 507-517
-
-
Cregan, S.P.1
Fortin, A.2
MacLaurin, J.G.3
Callaghan, S.M.4
Cecconi, F.5
Yu, S.W.6
Dawson, T.M.7
Dawson, V.L.8
Park, D.S.9
Kroemer, G.10
Slack, R.S.11
-
73
-
-
20244364788
-
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite
-
Zhang, X., Chen, J., Graham, S. H., Du, L., Kochanek, P. M., Draviam, R., Guo, F., Nathaniel, P. D., Szabo, G., Watkins, S. C., and Clark, R. S. 2002. Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J. Neurochem. 82:181-191.
-
(2002)
J. Neurochem.
, vol.82
, pp. 181-191
-
-
Zhang, X.1
Chen, J.2
Graham, S.H.3
Du, L.4
Kochanek, P.M.5
Draviam, R.6
Guo, F.7
Nathaniel, P.D.8
Szabo, G.9
Watkins, S.C.10
Clark, R.S.11
-
74
-
-
0038043242
-
+ depletion and cell death induced by oxidative stress
-
Mar 7 (epub ahead of print)
-
+ depletion and cell death induced by oxidative stress. J. Biol. Chem. Mar 7 (epub ahead of print).
-
(2003)
J. Biol. Chem.
-
-
Du, L.1
Zhang, X.2
Han, Y.Y.3
Burke, N.A.4
Kochanek, P.M.5
Watkins, S.C.6
Graham, S.H.7
Carcillo, J.A.8
Szabo, C.9
Clark, R.S.10
-
75
-
-
0035674047
-
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
-
van Loo, G., Schotte, P., van Gurp, M., Demol, H., Hoorelbeke, B., Gevaert, K., Rodriguez, I., Ruiz Carrillo, A., Vandekerekhove, J., Declereq, W., Boyaert, R., and Vandenabeele, P. 2001. Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation. Cell. Death Differ. 8:1136-1142.
-
(2001)
Cell. Death Differ.
, vol.8
, pp. 1136-1142
-
-
Van Loo, G.1
Schotte, P.2
Van Gurp, M.3
Demol, H.4
Hoorelbeke, B.5
Gevaert, K.6
Rodriguez, I.7
Ruiz Carrillo, A.8
Vandekerekhove, J.9
Declereq, W.10
Boyaert, R.11
Vandenabeele, P.12
-
76
-
-
0037191413
-
Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion
-
Shibata, M., Hattori, H., Sasaki, T., Gotoh, J., Hamada, J., and Fukuuchi, Y. 2002. Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion. Neuroreport 13:1985-1988.
-
(2002)
Neuroreport
, vol.13
, pp. 1985-1988
-
-
Shibata, M.1
Hattori, H.2
Sasaki, T.3
Gotoh, J.4
Hamada, J.5
Fukuuchi, Y.6
-
77
-
-
0037072873
-
Mechanisms of p75-mediated death of hippocampal neurons: Role of caspases
-
Troy, C. M., Friedman, J. E., and Friedman, W. J. 2002. Mechanisms of p75-mediated death of hippocampal neurons: Role of caspases. J. Biol. Chem. 277:34295-342302.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34295-342302
-
-
Troy, C.M.1
Friedman, J.E.2
Friedman, W.J.3
-
78
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki, Y., Imai, Y., Nakayama, H., Takahashi, K., Takio, K., and Takahashi, R. 2001. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol. Cells 8:613-621.
-
(2001)
Mol. Cells
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
79
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
Wang, X., Yang, C., Chai, J., Shi, Y., and Xue, D. 2002. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 298:1587-1592.
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chai, J.3
Shi, Y.4
Xue, D.5
-
80
-
-
0032192529
-
Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c
-
Deshmuckh, M. and Johnson E. M. Jr. 1998. Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c. Neuron 21:6?
-
(1998)
Neuron
, vol.21
, pp. 6
-
-
Deshmuckh, M.1
Johnson Jr., E.M.2
-
81
-
-
0037107134
-
Exogenous Smac induces competence and permits caspase activation in sympathetic neurons
-
Deshmukh, M., Du, C., Wang, X., and Johnson, E. M. Jr. 2002. Exogenous Smac induces competence and permits caspase activation in sympathetic neurons. J. Neurosci. 22:8018-8027.
-
(2002)
J. Neurosci.
, vol.22
, pp. 8018-8027
-
-
Deshmukh, M.1
Du, C.2
Wang, X.3
Johnson Jr., E.M.4
-
82
-
-
0034658350
-
Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2
-
Haraguchi, M., Torii, S., Matsuzawa, S., Xie, Z., Kitada, S., Krajewski, S., Yoshida, H., Mak, T. W., and Reed, J. C. 2000. Apoptotic protease activating factor 1 (Apaf-1)-independent cell death suppression by Bcl-2. J. Exp. Med. 191:1709-1720.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1709-1720
-
-
Haraguchi, M.1
Torii, S.2
Matsuzawa, S.3
Xie, Z.4
Kitada, S.5
Krajewski, S.6
Yoshida, H.7
Mak, T.W.8
Reed, J.C.9
-
83
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden, V. S., O'Connor, L., O'Reilly, L. A., Silke, J., Metcalf, D., Ekert, P. G., Huang, D. C., Cecconi, F., Kuida, K., Tomaselli, K. J., Roy, S., Nicholson, D. W., Vaux, D. L., Bouillet, P., Adams, J. M., and Strassor, A. 2002. Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419:634-637.
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
Silke, J.4
Metcalf, D.5
Ekert, P.G.6
Huang, D.C.7
Cecconi, F.8
Kuida, K.9
Tomaselli, K.J.10
Roy, S.11
Nicholson, D.W.12
Vaux, D.L.13
Bouillet, P.14
Adams, J.M.15
Strassor, A.16
-
84
-
-
0030916417
-
DFF: A heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
-
Liu, X., Zou, H., Slaughter, C., and Wang, X. 1997. DFF: A heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89:175-184.
-
(1997)
Cell
, vol.89
, pp. 175-184
-
-
Liu, X.1
Zou, H.2
Slaughter, C.3
Wang, X.4
-
85
-
-
0036431535
-
Caspase-3-dependent and -independent apoptosis in focal brain ischemia
-
Didenko, V. V., Ngo, H., Minchew, C. L., Boudreaux, D. J., Widmayer, M. A., and Baskin, D. S. 2002. Caspase-3-dependent and -independent apoptosis in focal brain ischemia. Mol. Med. 8:347-352.
-
(2002)
Mol. Med.
, vol.8
, pp. 347-352
-
-
Didenko, V.V.1
Ngo, H.2
Minchew, C.L.3
Boudreaux, D.J.4
Widmayer, M.A.5
Baskin, D.S.6
-
86
-
-
0035894881
-
Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
-
Viswanath, V., Wu, Y., Boonplueang, R., Chen, S., Stevenson, F. F., Yantiri, F., Yang, L., Beal, M. F., and Andersen, J. K. 2001. Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease. J. Neurosci. 21:9519-9528.
-
(2001)
J. Neurosci.
, vol.21
, pp. 9519-9528
-
-
Viswanath, V.1
Wu, Y.2
Boonplueang, R.3
Chen, S.4
Stevenson, F.F.5
Yantiri, F.6
Yang, L.7
Beal, M.F.8
Andersen, J.K.9
-
87
-
-
0033010059
-
Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis
-
McGinnis, K. M., Gnegy, M. E., and Wang, K. K. 1999. Endogenous bax translocation in SH-SY5Y human neuroblastoma cells and cerebellar granule neurons undergoing apoptosis. J. Neurochem. 72:1899-1906.
-
(1999)
J. Neurochem.
, vol.72
, pp. 1899-1906
-
-
McGinnis, K.M.1
Gnegy, M.E.2
Wang, K.K.3
-
88
-
-
0037193473
-
Intrinsic and extrinsic pathway signaling during neuronal apoptosis: Lessons from the analysis of mutant mice
-
Putcha, G. V., Harris, C. A., Moulder, K. L., Easton, R. M., Thompson, C. B., and Johnson, E. M. Jr. 2002. Intrinsic and extrinsic pathway signaling during neuronal apoptosis: Lessons from the analysis of mutant mice. J. Cell. Biol. 157:441-453.
-
(2002)
J. Cell. Biol.
, vol.157
, pp. 441-453
-
-
Putcha, G.V.1
Harris, C.A.2
Moulder, K.L.3
Easton, R.M.4
Thompson, C.B.5
Johnson Jr., E.M.6
-
89
-
-
0036847178
-
Membrane perturbations induced by the apoptotic Bax protein
-
Epand, R. F., Martinou, J. C., Montessuit, S., and Epand, R. M. 2002. Membrane perturbations induced by the apoptotic Bax protein. Biochem. J. 367:849-855.
-
(2002)
Biochem. J.
, vol.367
, pp. 849-855
-
-
Epand, R.F.1
Martinou, J.C.2
Montessuit, S.3
Epand, R.M.4
-
90
-
-
0036565774
-
Bid induces cytochrome c-impermeable Bax channels in liposomes
-
Roucou, X., Rostovtseva, T., Montessuit, S., Martinou, J. C., and Antonsson, B. 2002. Bid induces cytochrome c-impermeable Bax channels in liposomes. Biochem. J. 363:547-552.
-
(2002)
Biochem. J.
, vol.363
, pp. 547-552
-
-
Roucou, X.1
Rostovtseva, T.2
Montessuit, S.3
Martinou, J.C.4
Antonsson, B.5
-
91
-
-
0036850312
-
Bid, bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana, T., Mackey, M. R., Perkins, G., Ellisman, M. H., Latterich, M., Schneiter, R., Green, D. R., and Newmeyer, D. D. 2002. Bid, bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell 111:331-342.
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
Mackey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
Green, D.R.7
Newmeyer, D.D.8
-
92
-
-
0029116916
-
The mitochondrial permeability transition
-
Zoratti, M. and Szabo, I. 1995. The mitochondrial permeability transition. Biochim. Biophys. Acta 1241:139-176.
-
(1995)
Biochim. Biophys. Acta
, vol.1241
, pp. 139-176
-
-
Zoratti, M.1
Szabo, I.2
-
93
-
-
0017089948
-
Relationship between configuration, function, and permeability in calcium-treated mitochondria
-
Hunter, D. R., Haworth, R. A., and Southard, J. H. 1976. Relationship between configuration, function, and permeability in calcium-treated mitochondria. J. Biol. Chem. 251:5069-5077.
-
(1976)
J. Biol. Chem.
, vol.251
, pp. 5069-5077
-
-
Hunter, D.R.1
Haworth, R.A.2
Southard, J.H.3
-
94
-
-
0032831667
-
Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver
-
Andreyev, A. and Fiskum, G. 1999. Calcium induced release of mitochondrial cytochrome c by different mechanisms selective for brain versus liver. Cell. Death Differ. 6:825-832.
-
(1999)
Cell. Death Differ.
, vol.6
, pp. 825-832
-
-
Andreyev, A.1
Fiskum, G.2
-
95
-
-
0035292649
-
2+ thresholds determine cytochrome c release of permeability transition pore opening in brain mitochondria
-
2+ thresholds determine cytochrome c release of permeability transition pore opening in brain mitochondria. FASEB J. 80:565-567.
-
(2001)
FASEB J.
, vol.80
, pp. 565-567
-
-
Schild, L.1
Keilhoff, G.2
Augustin, W.3
Reiser, G.4
Striggow, F.5
-
96
-
-
0030741693
-
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition
-
Hortelano, S., Dallaporta, B., Zamzami, N., Hirsch, T., Susin, S. A., Marzo, I., Bosca, L., and Kroemer, G. 1997. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett. 410:373-377.
-
(1997)
FEBS Lett.
, vol.410
, pp. 373-377
-
-
Hortelano, S.1
Dallaporta, B.2
Zamzami, N.3
Hirsch, T.4
Susin, S.A.5
Marzo, I.6
Bosca, L.7
Kroemer, G.8
-
97
-
-
0032504568
-
The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy
-
Lemasters, J. J., Nieminen, A. L., Qian, T., Trost, L. C., Elmore, S. P., Nishimura, Y., Crowe, R. A., Cascio, W. E., Bradham, C. A., Brenner, D. A., and Herman, B. 1998. The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy. Biochim. Biophys. Acta 1366:177-196.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 177-196
-
-
Lemasters, J.J.1
Nieminen, A.L.2
Qian, T.3
Trost, L.C.4
Elmore, S.P.5
Nishimura, Y.6
Crowe, R.A.7
Cascio, W.E.8
Bradham, C.A.9
Brenner, D.A.10
Herman, B.11
-
98
-
-
0032550363
-
The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
-
Marzo, I., Brenner, C., Zamzami, N., Susin, S. A., Beutner, G., Brdiczka, D., Remy, R., Xie, Z. H., Reed, J. C., and Kroemer, G. 1998. The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins. J. Exp. Med. 187:1261-1271.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1261-1271
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Susin, S.A.4
Beutner, G.5
Brdiczka, D.6
Remy, R.7
Xie, Z.H.8
Reed, J.C.9
Kroemer, G.10
-
99
-
-
0031772126
-
The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release
-
Bradham, C. A., Qian, T., Streetz, K., Trautwein, C., Brenner, D. A., and Lemasters, J. J. 1998. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Mol. Cell Biol. 18:6353-6364.
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6353-6364
-
-
Bradham, C.A.1
Qian, T.2
Streetz, K.3
Trautwein, C.4
Brenner, D.A.5
Lemasters, J.J.6
-
100
-
-
0033605376
-
Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells
-
Heiskanen, K. M., Bhat, M. B., Wang, H. W., Ma, J., and Nieminen, A. L. 1999. Mitochondrial depolarization accompanies cytochrome c release during apoptosis in PC6 cells. J. Biol. Chem. 274:5654-5658.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 5654-5658
-
-
Heiskanen, K.M.1
Bhat, M.B.2
Wang, H.W.3
Ma, J.4
Nieminen, A.L.5
-
101
-
-
0032472329
-
Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization
-
Bossy-Wetzel, E., Newmeyer, D. D., and Green, D. R. 1998. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization. EMBO J. 17:37-49.
-
(1998)
EMBO J.
, vol.17
, pp. 37-49
-
-
Bossy-Wetzel, E.1
Newmeyer, D.D.2
Green, D.R.3
-
102
-
-
0033781027
-
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
-
Goldstein, J. C., Waterhouse, N. J., Juin, P., Evan, G. I., and Green, D. R. 2000. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat. Cell Biol. 2:156-162.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 156-162
-
-
Goldstein, J.C.1
Waterhouse, N.J.2
Juin, P.3
Evan, G.I.4
Green, D.R.5
-
103
-
-
0031795088
-
Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential
-
Zhuang, J., Dinsdale, D., and Cohen, G. M. 1998. Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential. Cell. Death Differ. 5:953-962.
-
(1998)
Cell. Death Differ.
, vol.5
, pp. 953-962
-
-
Zhuang, J.1
Dinsdale, D.2
Cohen, G.M.3
-
104
-
-
0033178444
-
Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
-
Stefanis, L., Park, D. S., Friedman, W. J., and Greene, L. A. Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. J. Neurosci. 19:6235-6247.
-
J. Neurosci.
, vol.19
, pp. 6235-6247
-
-
Stefanis, L.1
Park, D.S.2
Friedman, W.J.3
Greene, L.A.4
-
105
-
-
0033198273
-
Mitochondrial depolarization is not required for neuronal apoptosis
-
Krohn, A. J., Wahlbrink, T., and Prehn, J. H. Mitochondrial depolarization is not required for neuronal apoptosis. J. Neurosci. 19:7394-7404.
-
J. Neurosci.
, vol.19
, pp. 7394-7404
-
-
Krohn, A.J.1
Wahlbrink, T.2
Prehn, J.H.3
-
106
-
-
0036313059
-
Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane
-
Brustovetsky, N., Brustovetsky, T., Jemmerson, R., and Dubinsky, J. M. 2002. Calcium-induced cytochrome c release from CNS mitochondria is associated with the permeability transition and rupture of the outer membrane. J. Neurochem. 80:207-218.
-
(2002)
J. Neurochem.
, vol.80
, pp. 207-218
-
-
Brustovetsky, N.1
Brustovetsky, T.2
Jemmerson, R.3
Dubinsky, J.M.4
-
107
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
Marzo, I., Brenner, C., Zamzami, N., Jurgensmeier, J. M., Susin, S. A., Vieira, H. L., Prevost, M. C., Xie, Z., Matsuyama, S., Reed, J. C., and Kroemer, G. 1998. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science 281:2027-2031.
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Jurgensmeier, J.M.4
Susin, S.A.5
Vieira, H.L.6
Prevost, M.C.7
Xie, Z.8
Matsuyama, S.9
Reed, J.C.10
Kroemer, G.11
-
108
-
-
0037164865
-
Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli
-
Arnoult, D., Parone, P., Martinou, J. C., Antonsson, B., Estaquier, J., and Ameisen, J. C. 2002. Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J. Cell Biol. 159:923-929.
-
(2002)
J. Cell Biol.
, vol.159
, pp. 923-929
-
-
Arnoult, D.1
Parone, P.2
Martinou, J.C.3
Antonsson, B.4
Estaquier, J.5
Ameisen, J.C.6
-
109
-
-
0142049202
-
Mitochondrial membrane permeabilization and superoxide production during apoptosis: A single-cell analysis
-
Dussmann, H., Kogel, D., Rehm, M., and Prehn, J. H. 2003. Mitochondrial membrane permeabilization and superoxide production during apoptosis: A single-cell analysis. J. Biol. Chem. 278:12645-12649.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 12645-12649
-
-
Dussmann, H.1
Kogel, D.2
Rehm, M.3
Prehn, J.H.4
-
110
-
-
0037416139
-
The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C
-
Murphy, B. M., O'Neill, A. J., Adrain, C., Watson, R. W., and Martin, S. J. 2003. The apoptosome pathway to caspase activation in primary human neutrophils exhibits dramatically reduced requirements for cytochrome C. J. Exp. Med. 197:625-632.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 625-632
-
-
Murphy, B.M.1
O'Neill, A.J.2
Adrain, C.3
Watson, R.W.4
Martin, S.J.5
-
111
-
-
0035865134
-
A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c
-
Mootha, V. K., Wei, M. C., Buttle, K. F., Scorrano, L., Panoutsakopoulou, V., Mannella, C. A., and Korsmeyer, S. J. 2001. A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c. EMBO J. 20:661-671.
-
(2001)
EMBO J.
, vol.20
, pp. 661-671
-
-
Mootha, V.K.1
Wei, M.C.2
Buttle, K.F.3
Scorrano, L.4
Panoutsakopoulou, V.5
Mannella, C.A.6
Korsmeyer, S.J.7
-
112
-
-
0035897408
-
Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process
-
Waterhouse, N. J., Goldstein, J. C., von Ahsen, O., Schuler, M., Newmeyer, D. D., and Green, D. R. 2001. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J. Cell Biol. 153:319-328.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 319-328
-
-
Waterhouse, N.J.1
Goldstein, J.C.2
Von Ahsen, O.3
Schuler, M.4
Newmeyer, D.D.5
Green, D.R.6
-
113
-
-
0034658288
-
Caspase-mediated degradation of AMPA receptor subunits: A mechanism for preventing excitotoxic necrosis and ensuring apoptosis
-
Glazner, G. W., Chan, S. L., Lu, C., and Mattson, M. P. 2000. Caspase-mediated degradation of AMPA receptor subunits: A mechanism for preventing excitotoxic necrosis and ensuring apoptosis. J. Neurosci. 20:3641-3649.
-
(2000)
J. Neurosci.
, vol.20
, pp. 3641-3649
-
-
Glazner, G.W.1
Chan, S.L.2
Lu, C.3
Mattson, M.P.4
-
114
-
-
0032557511
-
Energy thresholds in brain mitochondria: Potential involvement in neurodegeneration
-
Davey, G. P., Peuchen, S., and Clark, J. B. 1998. Energy thresholds in brain mitochondria: Potential involvement in neurodegeneration. J. Biol. Chem. 80:12753-12757.
-
(1998)
J. Biol. Chem.
, vol.80
, pp. 12753-12757
-
-
Davey, G.P.1
Peuchen, S.2
Clark, J.B.3
-
115
-
-
0034087277
-
Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity
-
D'Herde, K., De Prest, B., Mussche, S., Schotte, P., Beyaert, R., Coster, R. V., and Roels, F. 2000. Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity. Cell Death Differ. 7:331-337.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 331-337
-
-
D'Herde, K.1
De Prest, B.2
Mussche, S.3
Schotte, P.4
Beyaert, R.5
Coster, R.V.6
Roels, F.7
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