Caspase inhibition extends the commitment to neuronal death beyond cytochrome c release to the point of mitochondrial depolarization

Journal of Cell Biology

Volumn 150, Issue 1, 2000, Pages 131-143

  Deshmukh, Mohanish ^a   Kuida, Keisuke ^b   Johnson Jr , Eugene M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

Author keywords

Apoptosis; Bax; Caspase 9; NGF; Sympathetic neurons

Indexed keywords

CASPASE; CYTOCHROME C OXIDASE; NERVE GROWTH FACTOR;

APOPTOSIS; ARTICLE; CELL SURVIVAL; ENZYME INHIBITION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SYMPATHETIC NERVE CELL;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 9; CASPASES; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; CYTOCHROME C GROUP; FLUORESCENT DYES; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; MITOCHONDRIA; NERVE GROWTH FACTOR; NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SYMPATHETIC NERVOUS SYSTEM; XANTHENES;

EID: 0034631832     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.150.1.131     Document Type: Article

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