Cleaving the oxidative repair protein Ape I enhances cell death mediated by granzyme A

Nature Immunology

Volumn 4, Issue 2, 2003, Pages 145-153

  Fan, Zusen ^a   Beresford, Paul J ^a   Zhang, Dong ^a   Xu, Zhan ^a   Novina, Carl D ^b   Yoshida, Akira ^c,d   Pommier, Yves ^c   Lieberman, Judy ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d UNIVERSITY OF FUKUI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APURINIC ENDONUCLEASE I; CASPASE; DNA BASE; ENDONUCLEASE; GRANZYME A; LYSINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL REGENERATION; CELL STRAIN K 562; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENDOPLASMIC RETICULUM; EXCISION REPAIR; GENE EXPRESSION; GENE OVEREXPRESSION; GENE SILENCING; HELA CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; MACROMOLECULE; OXIDATION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN TARGETING; SENSITIVITY ANALYSIS;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CARBON-OXYGEN LYASES; DNA; DNA REPAIR; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; GENE SILENCING; GRANZYMES; HELA CELLS; HUMANS; K562 CELLS; MACROMOLECULAR SUBSTANCES; MEMBRANE GLYCOPROTEINS; OXIDATION-REDUCTION; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT PROTEINS; RNA INTERFERENCE; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0037318731     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni885     Document Type: Article

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