Granzyme A Activates an Endoplasmic Reticulum-associated Caspase-independent Nuclease to Induce Single-stranded DNA Nicks

Journal of Biological Chemistry

Volumn 276, Issue 46, 2001, Pages 43285-43293

  Beresford, Paul J ^b   Zhang, Dong ^b   Oh, David Y ^b   Fan, Zusen ^b   Greer, Eric L ^b   Russo, Melissa L ^b   Jaju, Madhuri ^b   Lieberman, Judy ^a  

^a CENTER FOR BLOOD RESEARCH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SUBSTRATES; TUMORS;

CELL DEATH PATHWAY;

ENZYMES;

CASPASE; DEOXYRIBONUCLEASE; GRANZYME A; NUCLEASE; NUCLEOSOME ASSEMBLY PROTEIN; PLASMID DNA; PP32 PROTEIN; PROTEIN; PROTEIN SET; SINGLE STRANDED DNA; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; GRANZYME; GZMA PROTEIN, HUMAN; MAGNESIUM; MEMBRANE PROTEIN; PERFORIN; PORE FORMING CYTOTOXIC PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE;

ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CYTOTOXIC T LYMPHOCYTE; DNA DAMAGE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; CELL DEATH; CELL LINE; CELL NUCLEUS; CHEMISTRY; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENE LIBRARY; GENETIC TRANSCRIPTION; METABOLISM; MOLECULAR GENETICS; PLASMID; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; RAT;

ANIMALIA;

AMINO ACID SEQUENCE; ANIMALS; CASPASES; CELL DEATH; CELL LINE; CELL NUCLEUS; DEOXYRIBONUCLEASES; DNA DAMAGE; DNA, COMPLEMENTARY; DNA, SINGLE-STRANDED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GENE LIBRARY; GRANZYMES; HUMANS; MAGNESIUM; MEMBRANE GLYCOPROTEINS; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; PLASMIDS; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; TRANSCRIPTION, GENETIC;

EID: 0035900714     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108137200     Document Type: Article

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