'Loop' domain is necessary for taxol-induced mobility shift and phosphorylation of Bcl-2 as well as for inhibiting taxol-induced cytosolic accumulation of cytochrome c and apoptosis

Cancer Research

Volumn 58, Issue 15, 1998, Pages 3202-3208

  Fang, Guofu ^a   Chang, Brian S ^b   Kim, Caryn N ^a   Perkins, Charles ^a   Thompson, Craig B ^b   Bhalla, Kapil N ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTARABINE; CYTOCHROME C; ETOPOSIDE; PACLITAXEL;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA CLEAVAGE; DRUG MECHANISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BINDING SITES; BLOTTING, WESTERN; CYTARABINE; CYTOCHROME C GROUP; CYTOSOL; DNA, NEOPLASM; ETOPOSIDE; HL-60 CELLS; HUMANS; MUTATION; PACLITAXEL; PHOSPHORYLATION; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; TRANSFECTION;

EID: 0032145442     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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