Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437

Journal of Cellular Physiology

Volumn 173, Issue 2, 1997, Pages 279-284

  Sun, Shi Yong ^a   Yue, Ping ^a   Shroot, Braham ^b   Hong, Waun K ^a   Lotan, Reuben ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b Ctr Intl Rech Dermatologiques G   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 [7 ADAMANTYL 6 [(2 METHOXYETHOXY)METHOXY] 2 NAPHTHYL]BENZOIC ACID; 6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; CD 2366; RETINOIC ACID; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

APOPTOSIS; CELL CULTURE; CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; CYTOCHEMISTRY; CYTOTOXICITY; DNA CONTENT; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG NON SMALL CELL CANCER; PRIORITY JOURNAL;

APOPTOSIS; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIVISION; HUMANS; LUNG NEOPLASMS; RECEPTORS, RETINOIC ACID; RETINOIDS; TRANSCRIPTION FACTOR AP-1; TUMOR CELLS, CULTURED;

EID: 0030780951     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199711)173:2<279::AID-JCP36>3.0.CO;2-8     Document Type: Conference Paper

References (27)

1. Angel, P., and Karin, M. (1991) The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072:129-157.
2. Benner, S.E., Lippman, S.M., and Hong, W.K. (1995) Current status of retinoid chemoprevention of lung cancer. Oncology, 9:205-210.
3. Bernard, B.A., Bernardon, J.-M., Delescluse, C., Martin, B., Lenoir, M.-C., Mangnan, J., Charpentier, B., Pilgrim, W.R., Reichert, U., and Shroot, B. (1992) Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptor γ. Biochem. Biophys. Res. Commun., 186:977-983.
4. Chambon, P. (1996) A decade of molecular biology of retinoic acid receptors. FASEB J., 10:940-954.
5. Chen, J.-Y., Penco, S., Ostrowski, J., Balaguer, P., Pons, M., Starrett, J.E., Reczek, P., Chambon, P., and Gronemeyer, H. (1995) RAR-specific agonist/antagonists which dissociate transactivation and API transrepression inhibit anchorage-independent cell proliferation. EMBO J., 14:1187-1197.
6. Compton, M.M. (1992) A biochemical hallmark of apoptosis: Internucleosomal degradation of the genome. Cancer Metastasis Rev., 11:105-119.
7. de The, H., Vivanco-Ruiz, M.M., Tiollais, P., Stunnenberg, H., and Dejean, A. (1990) Identification of a retinoic acid responsive element in the retinoic acid receptor β gene. Nature (London), 343:177-180.
8. Fanjul, A., Dawson, M.I., Hobbs, P.D., Jong, L., Cameron, J.F., Harlev, E., Graupner, G., Lu, X.-P., and Pfahl, M. (1994) A new class of retinoids with selective inhibition of AP-1 inhibits proliferation. Nature (London), 372:107-110.
9. Geradts, J., Chen, J.-Y., Russell, E.K., Yankaskas, J.R., Nieves, L., and Minna, J.D. (1993) Human lung cancer cells exhibit resistance to retinoic acid treatment. Cell Growth Differ., 4:799-809.
10. Gudas, L.J., Sporn, M.B., and Roberts, A.B. (1994) Cellular biology and biochemistry of the retinoids. In: The Retinoids. M.B. Sporn, A.B. Roberts, and D.S. Goodman, eds. Raven Press, New York, pp. 443-520.
11. Hong, W.K., and Itri, L.M. (1994) Retinoids and human cancer. In: The Retinoids. M.B. Sporn, A.B. Roberts, and D.S. Goodman, eds. Raven Press, New York, pp. 597-658.
12. Jetten, A.M., Nervi, C., and Vollberg, T.M. (1992) Control of squamous differentiation in tracheobronchial and epidermal epithelial cells: Role of retinoids. J. Natl. Cancer Inst. Monogr., 13:93-100.
13. Kim, Y.-H., Dohi, D.F., Han, G.R., Zou, C.-P., Oridate, N., Walsh, G.L., Nesbitt, J.C., Xu, X.-C., Hong, W.K., Lotan, R., and Kurie, J.M. (1995) Retinoid refractoriness occurs during lung carcinogenesis despite functional retinoid receptors. Cancer Res., 55:5603-5610.
14. Lotan, R. (1995a) Retinoids and apoptosis: Implications for cancer chemoprevention and therapy (editorial). J. Natl. Cancer Inst., 87:1655-1657.
15. Lotan, R. (1995b) Cellular biology of the retinoids. In: Retinoids in Oncology. L. Degos and D.R. Parkinson, eds. Springer, Berlin, pp. 27-42.
16. Mangelsdorf, D.J., Umesono, K., and Evans, R.M. (1994) The retinoid receptors. In: The Retinoids. M.B. Sporn, A.B. Roberts, and D.S. Goodman, eds. Raven Press, New York, pp. 319-349.
17. Martin, S.J., and Green, D.R. (1994) Apoptosis as a goal of cancer therapy. Curr. Opin. Oncol., 6:616-621.
18. Monks, A., Scudiero, D., Skehan, P., Shoemaker, R., Paul, K., Vistica, D., Hose, C., Langley, J., Cronise, P., Vaigro-Wolff, A., Gray-Goodrich, M., Campbell, H., Mayo, J., and Boyd, M.R. (1991) Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. J. Natl. Cancer Inst., 83:757-766.
19. Nicoletti, I., Migliorati, G., Pagliacci, M.C., Grignani, F., and Riccardi, C. (1991) A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods, 139:271-279.
20. Oridate, N., Esumi, N., Lotan, D., Hong, W.K., Rochette-Egly, C., Chambon, P., and Lotan, R. (1996) Implication of retinoic acid receptor g in squamous differentiation and response to retinoic acid in head and neck SqCC/Y1 squamous carcinoma cells. Oncogene, 12:2019-2028.
21. Oridate, N., Higuchi M., Suzuki, S., Shroot, B., Hong, W.K., and Lotan, R. (1997) Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437). Int. J. Cancer, 70:484-487.
22. Parker, S.L., Tong, T., Bolden, S., and Wingo, P.A. (1997) Cancer statistics, 1997. CA Cancer J. Clin., 47:5-27.
23. Pfahl, M. (1992) Nuclear receptor/AP-1 interaction. Endocrinol. Rev., 14:651-658.
24. Pfahl, M., Tzukerman, M., Zang, X.-K., Lehmann, J.M., Hermann, T., Wills, K.N., and Graupner, G. (1990) Nuclear retinoic acid receptors: Cloning, analysis, and function. Methods Enzymol., 189:256-271.
25. 1 arrest and apoptosis induced by a novel retinoid in human breast cancer cells. Oncogene, 83:493-504.
26. Smith, M.A., Parkinson, D.R., Cheson, B.D., and Friedman, M.A. (1992) Retinoids in cancer therapy. J. Clin. Oncol., 10:839-864.
27. Sun, S.-Y., Yue, P., Hong, W.K., and Lotan, R. (1996) Differential growth inhibitory effects of RAR-/RXR-selective retinoids in head and neck and lung cancer cells. Proc. Am. Assoc. Cancer Res., 37:232.