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Volumn 60, Issue 7, 2000, Pages 2025-2032

S-phase arrest and apoptosis induced in normal mammary epithelial cells by a novel retinoid

Author keywords

[No Author keywords available]

Indexed keywords

6 [3 (1 ADAMANTYL) 4 HYDROXYPHENYL] 2 NAPHTHOIC ACID; CYCLIN DEPENDENT KINASE 2; PROTEIN P21; TRANSCRIPTION FACTOR E2F;

EID: 0034070373     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (45)

References (56)
  • 1
    • 0002020447 scopus 로고
    • Cellular biology and biochemistry of the retinoids
    • M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
    • Gudas, L. J., Sporn, M. B., and Roberts, A. B. Cellular biology and biochemistry of the retinoids. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids: Biology, Chemistry, and Medicine, 2nd ed., pp. 443-520. New York: Raven Press, 1994.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine, 2nd Ed. , pp. 443-520
    • Gudas, L.J.1    Sporn, M.B.2    Roberts, A.B.3
  • 2
    • 0002503191 scopus 로고
    • Retinoids in development
    • M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
    • Hofmann, C., and Eichele, G. Retinoids in development. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids: Biology, Chemistry, and Medicine, 2nd ed., pp. 387-442. New York: Raven Press, 1994.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine, 2nd Ed. , pp. 387-442
    • Hofmann, C.1    Eichele, G.2
  • 3
    • 0008936234 scopus 로고
    • Retinoids: Achievements, prospectives, and future goals
    • S. Waxman (ed.), Rome: Ares-Serono Symposia Publications
    • Bollag, W., Apfel, C., and LeMotte, P. Retinoids: achievements, prospectives, and future goals. In: S. Waxman (ed.), Differentialion Therapy: Challenges of Modern Medicine, Vol. 10., pp. 285-302. Rome: Ares-Serono Symposia Publications, 1995.
    • (1995) Differentialion Therapy: Challenges of Modern Medicine , vol.10 , pp. 285-302
    • Bollag, W.1    Apfel, C.2    LeMotte, P.3
  • 5
    • 0033523269 scopus 로고    scopus 로고
    • Nuclear retinoic acid receptors β in bronchial epithelium of smokers before and during chemoprevention
    • Xu, X. C., Lee, J. S., Lee, J. J., Morice, R. C., Liu, X., Lippman, S. M., Hong, W. K., and Lotan, R. Nuclear retinoic acid receptors β in bronchial epithelium of smokers before and during chemoprevention. J. Natl. Cancer Inst., 91: 1317-1321, 1999.
    • (1999) J. Natl. Cancer Inst. , vol.91 , pp. 1317-1321
    • Xu, X.C.1    Lee, J.S.2    Lee, J.J.3    Morice, R.C.4    Liu, X.5    Lippman, S.M.6    Hong, W.K.7    Lotan, R.8
  • 6
    • 0001319804 scopus 로고
    • Retinoids and human cancer
    • M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), New York: Raven Press
    • Hong, W. K., and Itri, L. M. Retinoids and human cancer. In: M. B. Sporn, A. B. Roberts, and D. S. Goodman (eds.), The Retinoids: Biology, Chemistry, and Medicine, 2nd ed., pp. 597-630. New York: Raven Press, 1994.
    • (1994) The Retinoids: Biology, Chemistry, and Medicine, 2nd Ed. , pp. 597-630
    • Hong, W.K.1    Itri, L.M.2
  • 7
    • 0028419153 scopus 로고
    • The retinoid signaling pathway: Molecular and genetic analyses
    • Chambon, P. The retinoid signaling pathway: molecular and genetic analyses. Semin. Cell Biol., 5: 115-125, 1994.
    • (1994) Semin. Cell Biol. , vol.5 , pp. 115-125
    • Chambon, P.1
  • 9
    • 0030992162 scopus 로고    scopus 로고
    • Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene
    • Kirfel, I., Kelter, M. Cancela, L. M., Price, P. A., and Schele, R. Identification of a novel negative retinoic acid responsive element in the promoter of the human Matrix Gla protein gene. Proc. Natl. Acad. Sci. USA, 94: 2227-2232, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2227-2232
    • Kirfel, I.1    Kelter, M.2    Cancela, L.M.3    Price, P.A.4    Schele, R.5
  • 10
    • 0027521592 scopus 로고
    • Nuclear receptor/AP-1 interaction
    • Pfahl, M. Nuclear receptor/AP-1 interaction. Endocr. Rev., 14: 651-658, 1993.
    • (1993) Endocr. Rev. , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 11
    • 0030873519 scopus 로고    scopus 로고
    • Retinyl methyl ether down-regulates activator protein 1 transcriptional activation in breast cancer cells
    • Agadir, A., Shealy, Y. F., Hill, D. L., and Zhang, X-K. Retinyl methyl ether down-regulates activator protein 1 transcriptional activation in breast cancer cells. Cancer Res., 57: 3444-3450, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3444-3450
    • Agadir, A.1    Shealy, Y.F.2    Hill, D.L.3    Zhang, X.-K.4
  • 12
    • 0030993666 scopus 로고    scopus 로고
    • Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells
    • Lee, H-Y., Dawson, M. I., Claret, F-X., Chen, J. D., Walsh, G. L., Hong, W. K., and Kurie, J. M. Evidence of a retinoid signaling alteration involving the activator protein 1 complex in tumorigenic human bronchial epithelial cells and non-small cell lung cancer cells. Cell Growth Differ., 8: 283-291, 1997.
    • (1997) Cell Growth Differ. , vol.8 , pp. 283-291
    • Lee, H.-Y.1    Dawson, M.I.2    Claret, F.-X.3    Chen, J.D.4    Walsh, G.L.5    Hong, W.K.6    Kurie, J.M.7
  • 13
    • 0030787752 scopus 로고    scopus 로고
    • Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status
    • Fitzgerald, P., Teng, M., Chandraratna, R. A. S., Heyman, R. A., and Allegretto, E. A. Retinoic acid receptor α expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status. Cancer Res., 57: 2642-2650, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2642-2650
    • Fitzgerald, P.1    Teng, M.2    Chandraratna, R.A.S.3    Heyman, R.A.4    Allegretto, E.A.5
  • 16
    • 0028819989 scopus 로고
    • Estradiol regulation of the human retinoic acid receptor α gene in human breast carcinoma cells is mediated via an imperfect half-palindromic estrogen response element and Sp 1 motifs
    • Rishi, A. K., Shao, Z-M., Baumann, R. G., Li, X-S., Sheikh, S., Kimura, S., Bashirelahi, N., and Fontana, J. A. Estradiol regulation of the human retinoic acid receptor α gene in human breast carcinoma cells is mediated via an imperfect half-palindromic estrogen response element and Sp 1 motifs. Cancer Res., 55: 4999-5006, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 4999-5006
    • Rishi, A.K.1    Shao, Z.-M.2    Baumann, R.G.3    Li, X.-S.4    Sheikh, S.5    Kimura, S.6    Bashirelahi, N.7    Fontana, J.A.8
  • 17
    • 0027742292 scopus 로고
    • Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RARα gene expression and sensitivity to growth inhibition by retinoic acid
    • Sheikh, M. S., Shao, Z-M., Chen, J-C., Hussain, A., Jetten, A. M., and Fontana, J. A. Estrogen receptor-negative breast cancer cells transfected with the estrogen receptor exhibit increased RARα gene expression and sensitivity to growth inhibition by retinoic acid. J. Cell. Biochem., 53: 394-404, 1993.
    • (1993) J. Cell. Biochem. , vol.53 , pp. 394-404
    • Sheikh, M.S.1    Shao, Z.-M.2    Chen, J.-C.3    Hussain, A.4    Jetten, A.M.5    Fontana, J.A.6
  • 19
    • 0032533844 scopus 로고    scopus 로고
    • Estrogen receptor expression activates the transcriptional and growth-inhibitory response to retinoids without enhanced retinoic acid receptor α expression
    • Rosenaver, A., Nervi, C., Davidson, K., Lamph, W. W., Mader, S., and Miller, W. H., Jr. Estrogen receptor expression activates the transcriptional and growth-inhibitory response to retinoids without enhanced retinoic acid receptor α expression. Cancer Res., 58: 5110-5116, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 5110-5116
    • Rosenaver, A.1    Nervi, C.2    Davidson, K.3    Lamph, W.W.4    Mader, S.5    Miller W.H., Jr.6
  • 22
    • 0031738682 scopus 로고    scopus 로고
    • Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways
    • Adachi, H., Adams, A., Hughes, F. M., Zhang, J., Cidlowski, J. A., and Jetten, A. M. Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways. Cell Death Differ., 5: 973-983, 1998.
    • (1998) Cell Death Differ. , vol.5 , pp. 973-983
    • Adachi, H.1    Adams, A.2    Hughes, F.M.3    Zhang, J.4    Cidlowski, J.A.5    Jetten, A.M.6
  • 24
    • 0029562846 scopus 로고
    • Synthesis structure affinity relationships and biological activities of ligand binding to retinoic acid receptor subtypes
    • Charpentier, B., Bernardon, J. M., Evstache, J., Millois, C., Martin, B., Michel, S., and Shroot, B. Synthesis structure affinity relationships and biological activities of ligand binding to retinoic acid receptor subtypes. J. Med. Chem., 38: 4993-5006, 1995.
    • (1995) J. Med. Chem. , vol.38 , pp. 4993-5006
    • Charpentier, B.1    Bernardon, J.M.2    Evstache, J.3    Millois, C.4    Martin, B.5    Michel, S.6    Shroot, B.7
  • 25
    • 0028063456 scopus 로고
    • Mechanisms of regulation of WAF1/CIP1 gene expression in human breast carcinoma. Role of p53-dependent and independent signal transduction pathway
    • Sheikh, M. S., Li, X. S., Chen, J. C., Shao, Z. M., Ordonez, J. V., and Fontana, J. A. Mechanisms of regulation of WAF1/CIP1 gene expression in human breast carcinoma. Role of p53-dependent and independent signal transduction pathway. Oncogene, 9: 3407-3415, 1994.
    • (1994) Oncogene , vol.9 , pp. 3407-3415
    • Sheikh, M.S.1    Li, X.S.2    Chen, J.C.3    Shao, Z.M.4    Ordonez, J.V.5    Fontana, J.A.6
  • 26
  • 27
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction
    • Chomczynski, P., and Sacchi, N. Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal. Biochem., 162: 156-161, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-161
    • Chomczynski, P.1    Sacchi, N.2
  • 28
    • 0028308441 scopus 로고
    • Retinoic acid inhibition of insulin like growth factor i stimulation of c-fos mRNA levels in a breast carcinoma cell line
    • Li, X-S., Chen, J. C., Sheikh, M. S., Shao, Z. M., and Fontana, J. A. Retinoic acid inhibition of insulin like growth factor I stimulation of c-fos mRNA levels in a breast carcinoma cell line. Exp. Cell Res., 211: 68-73, 1994.
    • (1994) Exp. Cell Res. , vol.211 , pp. 68-73
    • Li, X.-S.1    Chen, J.C.2    Sheikh, M.S.3    Shao, Z.M.4    Fontana, J.A.5
  • 30
    • 0029006239 scopus 로고
    • Analysis of small cell lung cancer cell growth inhibition by 13-cis-retinoic acid. Importance of bioavailability
    • Avis, I., Mathias, A., Unsworth, E. J., Miller, M. J., Cuttitta, F., Mulshine, J. L., and Jakowlew, S. B. Analysis of small cell lung cancer cell growth inhibition by 13-cis-retinoic acid. Importance of bioavailability. Cell Growth Differ., 6: 485-492, 1995.
    • (1995) Cell Growth Differ. , vol.6 , pp. 485-492
    • Avis, I.1    Mathias, A.2    Unsworth, E.J.3    Miller, M.J.4    Cuttitta, F.5    Mulshine, J.L.6    Jakowlew, S.B.7
  • 32
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Washington DC
    • Steller, H., Mechanisms and genes of cellular suicide. Science (Washington DC), 267: 1445-1448, 1995.
    • (1995) Science , vol.267 , pp. 1445-1448
    • Steller, H.1
  • 33
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early maker of chemotherapy-induced apoptosis
    • Kaufmann, S. H., Desnoyers, S., Ottaviano, Y., Davidson, N. E., and Poirer, G. G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early maker of chemotherapy-induced apoptosis. Cancer Res., 53: 3976-3985, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirer, G.G.5
  • 34
    • 0028362359 scopus 로고
    • Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase
    • Krek, W., Ewen, M. E., Shirodkar, S., Arany, Z., Kaelin, W. G., Jr., and Livingston, D. M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell, 78: 161-172, 1994.
    • (1994) Cell , vol.78 , pp. 161-172
    • Krek, W.1    Ewen, M.E.2    Shirodkar, S.3    Arany, Z.4    Kaelin W.G., Jr.5    Livingston, D.M.6
  • 35
    • 0029559027 scopus 로고
    • Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint
    • Krek, W., Xu, G., and Livingston, D. M. Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell, 83: 1149-1158, 1995.
    • (1995) Cell , vol.83 , pp. 1149-1158
    • Krek, W.1    Xu, G.2    Livingston, D.M.3
  • 36
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
    • Qin, X-Q., Livingston, D. M., Kaelin, W. G., Jr., and Adams, P. D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 91: 10918-10922, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin W.G., Jr.3    Adams, P.D.4
  • 37
    • 0027936686 scopus 로고
    • Differential regulation of E2F transactivation by cyclin/cdk 2 complexes
    • Dynlacht, B. D., Flores, D., Lees, J. A., and Harlow, E. Differential regulation of E2F transactivation by cyclin/cdk 2 complexes. Genes Dev., 8: 1772-1786, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 1772-1786
    • Dynlacht, B.D.1    Flores, D.2    Lees, J.A.3    Harlow, E.4
  • 41
    • 0030960146 scopus 로고    scopus 로고
    • Induction of apoptosis by retinoids and retinoic acid receptor γ-selective compounds in mouse thymocytes through a novel apoptosis pathway
    • Szondy, Z., Reichert, U., Bernardon, J. M., Michel, S., Toth, R., Ancian, P., Aszner, E., and Fesus, L. Induction of apoptosis by retinoids and retinoic acid receptor γ-selective compounds in mouse thymocytes through a novel apoptosis pathway. Mol. Pharmacol., 51: 972-982, 1997.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 972-982
    • Szondy, Z.1    Reichert, U.2    Bernardon, J.M.3    Michel, S.4    Toth, R.5    Ancian, P.6    Aszner, E.7    Fesus, L.8
  • 42
    • 0033557347 scopus 로고    scopus 로고
    • A synthetic retinoid, CD437, induces S-phase arrest and apoptosis in the human prostate cancer cells. LNCaP and PC-3
    • Liang, J-Y., Fontana, J. A., Rao, J. N., Ordonez, I. V., Dawson, M. I., Shroot, B., Wilber, J. F., and Feng, P. A synthetic retinoid, CD437, induces S-phase arrest and apoptosis in the human prostate cancer cells. LNCaP and PC-3. Prostate, 38: 228-236, 1999.
    • (1999) Prostate , vol.38 , pp. 228-236
    • Liang, J.-Y.1    Fontana, J.A.2    Rao, J.N.3    Ordonez, I.V.4    Dawson, M.I.5    Shroot, B.6    Wilber, J.F.7    Feng, P.8
  • 44
    • 0032542284 scopus 로고    scopus 로고
    • Primary keratinocytes have an adhesion dependent S phase check point that is absent in immortalized cell lines
    • Hauser, P. J., Agrawal, D., and Pledger, W. J. Primary keratinocytes have an adhesion dependent S phase check point that is absent in immortalized cell lines. Oncogene, 17: 3083-3092, 1998.
    • (1998) Oncogene , vol.17 , pp. 3083-3092
    • Hauser, P.J.1    Agrawal, D.2    Pledger, W.J.3
  • 45
    • 0027537043 scopus 로고
    • Interactions of the p107 and R6 proteins with E2F during the cell proliferation response
    • Schwartz, J. K., Devoto, S. H., Smith, E. J., Chellapan, S. P., Jakoi, L., and Nevins, J. R. Interactions of the p107 and R6 proteins with E2F during the cell proliferation response. EMBO J., 12: 1013-1020, 1993.
    • (1993) EMBO J. , vol.12 , pp. 1013-1020
    • Schwartz, J.K.1    Devoto, S.H.2    Smith, E.J.3    Chellapan, S.P.4    Jakoi, L.5    Nevins, J.R.6
  • 47
    • 0027947383 scopus 로고
    • Deregulated transcription factor E2F-1 expression leads to S phase entry and p53-mediated apoptosis
    • Qin, X-Q., Livingston, D. M., Kaelin, W. G., Jr., and Adams, I. D. Deregulated transcription factor E2F-1 expression leads to S phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA, 91: 10918-10922, 1994.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 10918-10922
    • Qin, X.-Q.1    Livingston, D.M.2    Kaelin W.G., Jr.3    Adams, I.D.4
  • 48
    • 0028061670 scopus 로고
    • Deregulated expression of E2F-1 induces S phase arrest and leads to apoptosis
    • Shan, B., and Lee, W. H. Deregulated expression of E2F-1 induces S phase arrest and leads to apoptosis. Mol. Cell. Biol., 14: 8166-8173, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8166-8173
    • Shan, B.1    Lee, W.H.2
  • 50
    • 0032939925 scopus 로고    scopus 로고
    • Transcription factor E2F-1 is upregulated in response to DNA damage in a matter analogous to that of p53
    • Blattner, C., Sparks, A., and Lane, D. Transcription factor E2F-1 is upregulated in response to DNA damage in a matter analogous to that of p53. Mol. Cell. Biol., 19: 3704-3713, 1999.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3704-3713
    • Blattner, C.1    Sparks, A.2    Lane, D.3
  • 51
    • 0028019279 scopus 로고
    • Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA binding activity of E2F-1/ DP-1 by phosphorylation
    • Xu, M., Sheppard, K-A., Peng, C-Y., Yee, A. S., and Piwnica-Worms, H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA binding activity of E2F-1/ DP-1 by phosphorylation. Mol. Cell. Biol., 14: 8420-8431, 1994.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 8420-8431
    • Xu, M.1    Sheppard, K.-A.2    Peng, C.-Y.3    Yee, A.S.4    Piwnica-Worms, H.5
  • 52
    • 0030610390 scopus 로고    scopus 로고
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells
    • waf1 leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. Cancer Res., 57: 2193-2199, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2193-2199
    • Li, W.W.1    Fan, J.2    Hochhauser, D.3    Bertino, J.R.4
  • 53
    • 0032514752 scopus 로고    scopus 로고
    • Activity and nature of p21 (WAF1) complexes during the cell cycle
    • Cai, K., and Dynlacht, B. D. Activity and nature of p21 (WAF1) complexes during the cell cycle. Proc. Natl. Acad. Sci. USA, 95: 12254-12259, 1998.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12254-12259
    • Cai, K.1    Dynlacht, B.D.2
  • 55
    • 2642689658 scopus 로고    scopus 로고
    • Proteases to die for
    • Cryns, V., and Yuan, J. Proteases to die for. Genes Dev., 12: 1551-1570, 1998.
    • (1998) Genes Dev. , vol.12 , pp. 1551-1570
    • Cryns, V.1    Yuan, J.2
  • 56
    • 0032575688 scopus 로고    scopus 로고
    • The bcl-2 protein family: Orbiters of cell survival
    • Washington DC
    • Adams, J. M., and Cory, S. The bcl-2 protein family: orbiters of cell survival. Science (Washington DC), 281: 1322-1326, 1998.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2


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