메뉴 건너뛰기




Volumn 5, Issue 11, 1998, Pages 973-983

Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma cells involves caspase-dependent and independent pathways

Author keywords

Apoptosis; Caspase; Cell proliferation; Lymphoma; Retinoids

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; CARBOXYLIC ACID DERIVATIVE; CYSTEINE PROTEINASE; DNA FRAGMENT; NAPHTHALENE DERIVATIVE; RETINOIC ACID; RETINOID DERIVATIVE;

EID: 0031738682     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400445     Document Type: Article
Times cited : (49)

References (58)
  • 1
    • 0032011418 scopus 로고    scopus 로고
    • Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cellls
    • Adachi H, Preston G, Harvat B, Dawson MI and Jetten AM (1998) Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cellls. Am. J Respir Cell. Mol. Biol. 18: 323-333
    • (1998) Am. J Respir Cell. Mol. Biol. , vol.18 , pp. 323-333
    • Adachi, H.1    Preston, G.2    Harvat, B.3    Dawson, M.I.4    Jetten, A.M.5
  • 3
    • 0029163224 scopus 로고
    • 9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation
    • Bissonnette RP, Brunner T, Lazarchik SB, Yoo NJ, Boehm MF, Green DR and Heyman RA (1995) 9-cis retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of fas ligand and requires retinoic acid receptor and retinoid X receptor activation. Mol Cell. Biol 15: 5576-5585
    • (1995) Mol Cell. Biol , vol.15 , pp. 5576-5585
    • Bissonnette, R.P.1    Brunner, T.2    Lazarchik, S.B.3    Yoo, N.J.4    Boehm, M.F.5    Green, D.R.6    Heyman, R.A.7
  • 5
    • 0026357656 scopus 로고
    • Intracellular signaling by 14-hydroxy-4, 14-retro-retinol
    • Buck J, Derguini F, Levi E, Nakanishi K and Hammerling U (1991) Intracellular signaling by 14-hydroxy-4, 14-retro-retinol. Science 254: 1654-1656
    • (1991) Science , vol.254 , pp. 1654-1656
    • Buck, J.1    Derguini, F.2    Levi, E.3    Nakanishi, K.4    Hammerling, U.5
  • 6
    • 0028362488 scopus 로고
    • Bcl-2 inhibits glucocorticoid-induced apoptosis but only partially blocks calcium ionophore or cycloheximide-regulated apoptosis in S49 cells
    • Caron-Leslie LM, Evans RB and Cidlowski JA (1994) Bcl-2 inhibits glucocorticoid-induced apoptosis but only partially blocks calcium ionophore or cycloheximide-regulated apoptosis in S49 cells. FASEB J. 8: 639-645
    • (1994) FASEB J. , vol.8 , pp. 639-645
    • Caron-Leslie, L.M.1    Evans, R.B.2    Cidlowski, J.A.3
  • 8
    • 0029782494 scopus 로고    scopus 로고
    • Cathepsin D protease mediates programmed cell death by Interferon-γ Fas/APO-1 and TNF-α
    • Deiss LP, Galinka H, Berissi H, Cohen O and Kimchi A (1996) Cathepsin D protease mediates programmed cell death by Interferon-γ Fas/APO-1 and TNF-α. EMBO J. 15: 3861-3870
    • (1996) EMBO J. , vol.15 , pp. 3861-3870
    • Deiss, L.P.1    Galinka, H.2    Berissi, H.3    Cohen, O.4    Kimchi, A.5
  • 10
    • 0029853389 scopus 로고    scopus 로고
    • Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways
    • Dubrez L, Savoy I, Hamman A and Solary E (1996) Pivotal role of a DEVD-sensitive step in etoposide-induced and Fas-mediated apoptotic pathways EMBO J. 15: 5504-5512
    • (1996) EMBO J. , vol.15 , pp. 5504-5512
    • Dubrez, L.1    Savoy, I.2    Hamman, A.3    Solary, E.4
  • 11
    • 0029978182 scopus 로고    scopus 로고
    • Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis
    • Enari M, Talanian RV, Wong WW and Nagata S (1996) Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis. Nature 380: 723-726
    • (1996) Nature , vol.380 , pp. 723-726
    • Enari, M.1    Talanian, R.V.2    Wong, W.W.3    Nagata, S.4
  • 13
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme
    • Fernandes-Alnemri T, Litwack G and Alnemri ES (1994) CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J. Biol. Chem. 269: 30761-30764
    • (1994) J. Biol. Chem. , vol.269 , pp. 30761-30764
    • Fernandes-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 14
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavneli Y, Sherman Y and Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119: 493-501
    • (1992) J. Cell Biol. , vol.119 , pp. 493-501
    • Gavneli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 15
    • 0027995188 scopus 로고
    • RA receptors and cellular retinoid binding proteins: Complex interplay in retinoid signaling
    • Giguère V (1994) RA receptors and cellular retinoid binding proteins: complex interplay in retinoid signaling. Endocrine Rev. 15: 61-79
    • (1994) Endocrine Rev. , vol.15 , pp. 61-79
    • Giguère, V.1
  • 16
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD and Korsmeyer SJ (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348: 334-336
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 18
    • 0026447129 scopus 로고
    • Retinoic acid inhibit activation-induced apoptosis in T cell hybridomas and thymocytes
    • Iwata M, Mukai M, Nakai Y and Iseki R (1992) Retinoic acid inhibit activation-induced apoptosis in T cell hybridomas and thymocytes. J. Immunol. 149: 3302-3308
    • (1992) J. Immunol. , vol.149 , pp. 3302-3308
    • Iwata, M.1    Mukai, M.2    Nakai, Y.3    Iseki, R.4
  • 19
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson MD, Weil M and Raff MC (1997) Programmed cell death in animal development. Cell 88: 347-354
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 20
    • 0030875552 scopus 로고    scopus 로고
    • Mutational analysis reveals that all-transretinoic acid, 9-cis-retinoic acid and antagonist interact with distinct binding determinants of RARα
    • Keidel S, Lamour FPY and Apfel CM (1997) Mutational analysis reveals that all-transretinoic acid, 9-cis-retinoic acid and antagonist interact with distinct binding determinants of RARα J. Biol. Chem. 272: 18267-18272
    • (1997) J. Biol. Chem. , vol.272 , pp. 18267-18272
    • Keidel, S.1    Lamour, F.P.Y.2    Apfel, C.M.3
  • 21
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria' a primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR and Newmeyer DD (1997) The release of cytochrome c from mitochondria' a primary site for Bcl-2 regulation of apoptosis. Science 275: 1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 22
    • 0028956550 scopus 로고
    • Regulators of cell death
    • Korsmeyer SJ (1995) Regulators of cell death. Trends Genet. 11: 101-105
    • (1995) Trends Genet. , vol.11 , pp. 101-105
    • Korsmeyer, S.J.1
  • 23
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat. Med. 3: 614-620
    • (1997) Nat. Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 24
    • 0029794385 scopus 로고    scopus 로고
    • The ICE family of cysteine proteases as effectors of cell death
    • Kumar S and Flavin MF (1996) The ICE family of cysteine proteases as effectors of cell death. Cell Death Differ 3: 255-267
    • (1996) Cell Death Differ , vol.3 , pp. 255-267
    • Kumar, S.1    Flavin, M.F.2
  • 26
    • 0031009716 scopus 로고    scopus 로고
    • Caspase activity is required for commitment to Fas-mediated apoptosis
    • Longthorne VL and Williams GT (1997) Caspase activity is required for commitment to Fas-mediated apoptosis. EMBO J. 16: 3805-3812
    • (1997) EMBO J. , vol.16 , pp. 3805-3812
    • Longthorne, V.L.1    Williams, G.T.2
  • 28
    • 0029802815 scopus 로고    scopus 로고
    • Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity
    • Martin SJ, Finucane DM, Amarante-Mendes GP, O'Brien GA and Green DR (1996) Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity J. Biol Chem. 271 28753-28756
    • (1996) J. Biol Chem. , vol.271 , pp. 28753-28756
    • Martin, S.J.1    Finucane, D.M.2    Amarante-Mendes, G.P.3    O'Brien, G.A.4    Green, D.R.5
  • 29
    • 0031033274 scopus 로고    scopus 로고
    • Inhibition of CED-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage or the Bcl-2 homologue Bak
    • McCarthy NJ, Whyte MKB, Gilbert CS and Evan GI (1997) Inhibition of CED-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage or the Bcl-2 homologue Bak. J. Cell Biol. 136: 215-227
    • (1997) J. Cell Biol. , vol.136 , pp. 215-227
    • McCarthy, N.J.1    Whyte, M.K.B.2    Gilbert, C.S.3    Evan, G.I.4
  • 30
    • 0026781986 scopus 로고
    • Bcl-2 transfer increases relative resistance of S49.1 and WEHI7.2 lymploid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
    • Miyashita T and Reed JC (1992) Bcl-2 transfer increases relative resistance of S49.1 and WEHI7.2 lymploid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res. 52: 5407-5411
    • (1992) Cancer Res. , vol.52 , pp. 5407-5411
    • Miyashita, T.1    Reed, J.C.2
  • 31
    • 0032513291 scopus 로고    scopus 로고
    • Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2
    • Monney L, Otter I, Olivier R, Ozer HL, Haas AL, Omura S and Borner C (1997) Defects in the ubiquitin pathway induce caspase-independent apoptosis blocked by Bcl-2. J. Biol. Chem 273: 6121-6131
    • (1997) J. Biol. Chem , vol.273 , pp. 6121-6131
    • Monney, L.1    Otter, I.2    Olivier, R.3    Ozer, H.L.4    Haas, A.L.5    Omura, S.6    Borner, C.7
  • 32
    • 0029815759 scopus 로고    scopus 로고
    • The role of programmed cell death as an emerging new concept for the pathogenesis of autoimmune diseases
    • Mountz JD, Zhou T, Su X, Wu J and Cheng J (1996) The role of programmed cell death as an emerging new concept for the pathogenesis of autoimmune diseases Clin. Immunol, Immunopathol. 80: S2-S14
    • (1996) Clin. Immunol, Immunopathol. , vol.80
    • Mountz, J.D.1    Zhou, T.2    Su, X.3    Wu, J.4    Cheng, J.5
  • 33
    • 0029068871 scopus 로고
    • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
    • Nicholson DL (1994) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43
    • (1994) Nature , vol.376 , pp. 37-43
    • Nicholson, D.L.1
  • 35
    • 0031018031 scopus 로고    scopus 로고
    • Rapid induction of apoptosis in human C33 cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437)
    • Ondate N, Higuchi M, Suzuki S, Shroot B, Hong WK and Lotan R (1997) Rapid induction of apoptosis in human C33 cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalene carboxylic acid (CD437). Int. J. Cancer 70: 484-487
    • (1997) Int. J. Cancer , vol.70 , pp. 484-487
    • Ondate, N.1    Higuchi, M.2    Suzuki, S.3    Shroot, B.4    Hong, W.K.5    Lotan, R.6
  • 36
    • 0030799123 scopus 로고    scopus 로고
    • Retinoid-induced apoptosis and Sp-1 cleavage occur independently of transcription and require caspase activation
    • Piedrafita FJ and Pfahl M (1997) Retinoid-induced apoptosis and Sp-1 cleavage occur independently of transcription and require caspase activation. Mol Cell. Biol. 17: 6348-6358
    • (1997) Mol Cell. Biol. , vol.17 , pp. 6348-6358
    • Piedrafita, F.J.1    Pfahl, M.2
  • 37
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2family
    • Reed JC (1997) Double identity for proteins of the Bcl-2family Nature 387: 773-776
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 40
    • 0030002801 scopus 로고    scopus 로고
    • Benzyloxycarbonyl-val-ala-asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32
    • Slee EA, Zhu H, Chow SC, MacFarlane M, Nicholson DW and Cohen GM (1996) Benzyloxycarbonyl-val-ala-asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32 Biochem J. 315: 21-24
    • (1996) Biochem J. , vol.315 , pp. 21-24
    • Slee, E.A.1    Zhu, H.2    Chow, S.C.3    MacFarlane, M.4    Nicholson, D.W.5    Cohen, G.M.6
  • 41
    • 0024492086 scopus 로고
    • Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
    • Smith CA, Williams GT, Kingston R, Jenkinson EJ and Owen JJT (1989) Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337: 181-184
    • (1989) Nature , vol.337 , pp. 181-184
    • Smith, C.A.1    Williams, G.T.2    Kingston, R.3    Jenkinson, E.J.4    Owen, J.J.T.5
  • 42
  • 43
    • 0030780951 scopus 로고    scopus 로고
    • Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437
    • Sun SY, Shroot B, Hong WK and Lotan R (1997) Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437 J Cell Physiol. 173: 279-284
    • (1997) J Cell Physiol. , vol.173 , pp. 279-284
    • Sun, S.Y.1    Shroot, B.2    Hong, W.K.3    Lotan, R.4
  • 44
    • 0030960146 scopus 로고    scopus 로고
    • Induction of apoptosis by retinoids and retinoic acid receptor gammaselective compounds in mouse thymocytes through a novel apoptosis pathway
    • Szondy Z, Reichert U, Bernardon JM, Michel S, Toth R, Ancian P, Ajzner E and Fesus L (1997) Induction of apoptosis by retinoids and retinoic acid receptor gammaselective compounds in mouse thymocytes through a novel apoptosis pathway. Mol Pharmacol. 51: 972-982
    • (1997) Mol Pharmacol. , vol.51 , pp. 972-982
    • Szondy, Z.1    Reichert, U.2    Bernardon, J.M.3    Michel, S.4    Toth, R.5    Ancian, P.6    Ajzner, E.7    Fesus, L.8
  • 45
    • 0028990125 scopus 로고
    • Yama/CPP32, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS and Dixit VM (1995) Yama/CPP32, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase Cell 81: 1-20
    • (1995) Cell , vol.81 , pp. 1-20
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 46
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267: 1456-1462
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 48
    • 0023647132 scopus 로고
    • Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells
    • Ucker DS (1987) Cytotoxic T lymphocytes and glucocorticoids activate an endogenous suicide process in target cells. Nature 327: 62-64
    • (1987) Nature , vol.327 , pp. 62-64
    • Ucker, D.S.1
  • 49
    • 0027276857 scopus 로고
    • 9-cis-retinoic acid inhibits activation-driven T-cell apoptosis: Implications for retinoid X receptor involvement in thymocyte development
    • Vacchio MS and Ashwell JD (1993) 9-cis-retinoic acid inhibits activation-driven T-cell apoptosis: implications for retinoid X receptor involvement in thymocyte development. Proc. Natl Acad. Sci USA 90: 6170-6174
    • (1993) Proc. Natl Acad. Sci USA , vol.90 , pp. 6170-6174
    • Vacchio, M.S.1    Ashwell, J.D.2
  • 50
    • 0029043888 scopus 로고
    • A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V
    • Vermes I, Haanen C, Steffens-Nakken H and Reutelingsperger C (1995) A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled annexin V. J Immunol Methods 184: 39-51
    • (1995) J Immunol Methods , vol.184 , pp. 39-51
    • Vermes, I.1    Haanen, C.2    Steffens-Nakken, H.3    Reutelingsperger, C.4
  • 51
    • 0030630211 scopus 로고    scopus 로고
    • Apoptosis an overview of the process and its relevance in disease
    • Webb SJ, Harrison DJ and Wyllie AH (1997) Apoptosis an overview of the process and its relevance in disease. Adv. Pharmacol. 41: 1-34
    • (1997) Adv. Pharmacol. , vol.41 , pp. 1-34
    • Webb, S.J.1    Harrison, D.J.2    Wyllie, A.H.3
  • 52
    • 0029906828 scopus 로고    scopus 로고
    • Bax-induced cell death may not require interleukin 1 β-converting enzyme-like proteases
    • Xiang J, Chao DT and Korsmeyer SJ (1996) Bax-induced cell death may not require interleukin 1 β-converting enzyme-like proteases Proc Natl. Acad. Sci. USA 93: 14559-14563
    • (1996) Proc Natl. Acad. Sci. USA , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 54
    • 0028938363 scopus 로고
    • Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: Inhibition of Fas ligand expression by retinoic acid and glucocorticoids
    • Yang Y, Mercep M, Ware CF and Ashwell JD (1995a) Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids. J. Exp. Med. 181: 1673-1682
    • (1995) J. Exp. Med. , vol.181 , pp. 1673-1682
    • Yang, Y.1    Mercep, M.2    Ware, C.F.3    Ashwell, J.D.4
  • 55
    • 0029097645 scopus 로고
    • Efficient inhibition of activation-induced Fas ligand up-regulation and T cell apoptosis by retinoids requires occupancy of both retinoid X receptors and retinoic acid receptors
    • Yang Y, Minucci S, Ozato K, Heyman RA and Ashwell JD (1995b) Efficient inhibition of activation-induced Fas ligand up-regulation and T cell apoptosis by retinoids requires occupancy of both retinoid X receptors and retinoic acid receptors J Biol. Chem. 270: 18672-18677
    • (1995) J Biol. Chem. , vol.270 , pp. 18672-18677
    • Yang, Y.1    Minucci, S.2    Ozato, K.3    Heyman, R.A.4    Ashwell, J.D.5
  • 57
    • 0345714424 scopus 로고    scopus 로고
    • Retinoids and apoptosis
    • (Ed) Sherbet GV and Bittar EE JAI Press
    • Zhang L-X and Jetten AM (1997) Retinoids and apoptosis. In. Advances in Organ Biology (Ed) Sherbet GV and Bittar EE JAI Press Vol.3 pp. 161-196
    • (1997) Advances in Organ Biology , vol.3 , pp. 161-196
    • Zhang, L.-X.1    Jetten, A.M.2
  • 58
    • 0028947023 scopus 로고
    • Evidence for the involvement of RA receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids
    • Zhang L-X, Mills KJ, Dawson MI, Collins SJ and Jetten AM (1995) Evidence for the involvement of RA receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J. Biol. Chem. 270: 6022-6029
    • (1995) J. Biol. Chem. , vol.270 , pp. 6022-6029
    • Zhang, L.-X.1    Mills, K.J.2    Dawson, M.I.3    Collins, S.J.4    Jetten, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.