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Volumn 38, Issue 3, 2000, Pages 94-110

The prognostic significance of membrane transport-associated multidrug resistance (MDR) proteins in leukemia

Author keywords

Leukemia; Membrane transport; Multidrug resistance proteins; Prognosis

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; EPIPODOPHYLLOTOXIN; GLYCOPROTEIN P; LUNG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN; VINCA ALKALOID;

EID: 0034012773     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: 10.5414/cpp38094     Document Type: Review
Times cited : (124)

References (183)
  • 1
    • 0028025021 scopus 로고
    • Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells
    • Abbaszadegan MR, Flutscher BW, Klimecki WT, List A, Dalton WS 1994 Analysis of multidrug resistance-associated protein (MRP) messenger RNA in normal and malignant hematopoietic cells. Cancer Res 54: 4676-4579
    • (1994) Cancer Res , vol.54 , pp. 4676-14579
    • Abbaszadegan, M.R.1    Flutscher, B.W.2    Klimecki, W.T.3    List, A.4    Dalton, W.S.5
  • 4
    • 0031839225 scopus 로고    scopus 로고
    • Biochemical and clinical aspects of efflux pump related resistance to anti-cancer drugs
    • Aszalos A and Ross DD 1998 Biochemical and clinical aspects of efflux pump related resistance to anti-cancer drugs. Anticancer Res 18: 2937-2944
    • (1998) Anticancer Res , vol.18 , pp. 2937-2944
    • Aszalos, A.1    Ross, D.D.2
  • 5
    • 0033053573 scopus 로고    scopus 로고
    • Combinations of P-glycoprotein blockers, verapamil, PSC 833, and cremophor act differently on the multidrug resistance-associated protein (MRP) and on P-glycoprotein
    • Aszalos A, Thompson K, Yin J, Ross D 1999 Combinations of P-glycoprotein blockers, verapamil, PSC 833, and cremophor act differently on the multidrug resistance-associated protein (MRP) and on P-glycoprotein. Anticancer Res 19: 1053-1064
    • (1999) Anticancer Res , vol.19 , pp. 1053-1064
    • Aszalos, A.1    Thompson, K.2    Yin, J.3    Ross, D.4
  • 6
    • 0024996306 scopus 로고
    • Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line
    • Baas F, Jongsma APM, Broxterman HJ, Arceci RJ, Housman D, Scheffer GL, Riethorst A, Van Groeningen M, Nieuwint AWM, Joenje H 1990 Non-P-glycoprotein mediated mechanism for multidrug resistance precedes P-glycoprotein expression during in vitro selection for doxorubicin resistance in a human lung cancer cell line. Cancer Res 50: 5392-5398
    • (1990) Cancer Res , vol.50 , pp. 5392-5398
    • Baas, F.1    Jongsma, A.P.M.2    Broxterman, H.J.3    Arceci, R.J.4    Housman, D.5    Scheffer, G.L.6    Riethorst, A.7    Van Groeningen, M.8    Nieuwint, A.W.M.9    Joenje, H.10
  • 8
    • 0028945582 scopus 로고
    • Expression of mdr1, mrp, topoisomerase IIα/β, and cyclin A in primary or relapsed states of acute lymphoblastic leukemias
    • Beck WT, Handgrettinger R, Dopfer R, Klingebiel T, Niethammer D, Gekeler V 1995 Expression of mdr1, mrp, topoisomerase IIα/β, and cyclin A in primary or relapsed states of acute lymphoblastic leukemias. Br J Haematol 89: 356-363
    • (1995) Br J Haematol , vol.89 , pp. 356-363
    • Beck, W.T.1    Handgrettinger, R.2    Dopfer, R.3    Klingebiel, T.4    Niethammer, D.5    Gekeler, V.6
  • 11
    • 0032430818 scopus 로고    scopus 로고
    • Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukemia cells predict a poor response to chemotherapy and reduced patient survival
    • Borg AG, Burgess R, Green LM, Scheper RJ, Liu Yin JA 1998 Overexpression of lung-resistance protein and increased P-glycoprotein function in acute myeloid leukemia cells predict a poor response to chemotherapy and reduced patient survival. Br J Haematol 103: 1083-1091
    • (1998) Br J Haematol , vol.103 , pp. 1083-1091
    • Borg, A.G.1    Burgess, R.2    Green, L.M.3    Scheper, R.J.4    Liu, Y.J.A.5
  • 12
    • 0031814889 scopus 로고    scopus 로고
    • Co-expression of multidrug resistance involved proteins: A flow-cytometric analysis
    • Boutonnat J, Bonnefoix T, Mousseau M, Seigneurin D, Ronot X 1998 Co-expression of multidrug resistance involved proteins: a flow-cytometric analysis. Anticancer Res 18: 2993-3000
    • (1998) Anticancer Res , vol.18 , pp. 2993-3000
    • Boutonnat, J.1    Bonnefoix, T.2    Mousseau, M.3    Seigneurin, D.4    Ronot, X.5
  • 13
    • 0028147453 scopus 로고
    • Mdr-1 gene expression in childhood acute lymphoblastic leukemias and lymphomas: A critical evaluation by four techniques
    • Brophy NA, Marie JP, Rajas VA, Warnke RA, McFall PJ, Smith SD, Sikic BI 1994 Mdr-1 gene expression in childhood acute lymphoblastic leukemias and lymphomas: a critical evaluation by four techniques. Leukemia 8: 327-335
    • (1994) Leukemia , vol.8 , pp. 327-335
    • Brophy, N.A.1    Marie, J.P.2    Rajas, V.A.3    Warnke, R.A.4    McFall, P.J.5    Smith, S.D.6    Sikic, B.I.7
  • 14
    • 0030952650 scopus 로고    scopus 로고
    • Transport proteins in drug resistance: Detection and prognostic significance in acute myeloid leukemia
    • Broxterman HJ, Schuurhuis GJ 1997a Transport proteins in drug resistance: detection and prognostic significance in acute myeloid leukemia. J Intern Med 242: 147-151
    • (1997) J Intern Med , vol.242 , pp. 147-151
    • Broxterman, H.J.1    Schuurhuis, G.J.2
  • 18
    • 0026602155 scopus 로고
    • Clinical significance of multidrug resistance p-glycoprotein expression on acute nonlymphoblastic leukemia cells and diagnosis
    • Campos L, Guyotat D, Archimbaud E, Calmard-Oriol P, Tsumo T, Tronchy J, Treille D, Fiere D 1992 Clinical significance of multidrug resistance P-glycoprotein expression on acute nonlymphoblastic leukemia cells and diagnosis. Blood 79: 473-476
    • (1992) Blood , vol.79 , pp. 473-476
    • Campos, L.1    Guyotat, D.2    Archimbaud, E.3    Calmard-Oriol, P.4    Tsumo, T.5    Tronchy, J.6    Treille, D.7    Fiere, D.8
  • 19
    • 0030732074 scopus 로고    scopus 로고
    • Simultaneous expression of P-glycoprotein and BCL-2 in acute myeloid leukemia blast cells
    • Campos L, Oriol P, Sabido O, Gyotat D 1997 Simultaneous expression of P-glycoprotein and BCL-2 in acute myeloid leukemia blast cells. Leuk Lymphoma 27: 119-125
    • (1997) Leuk Lymphoma , vol.27 , pp. 119-125
    • Campos, L.1    Oriol, P.2    Sabido, O.3    Gyotat, D.4
  • 20
    • 0027005480 scopus 로고
    • Activation of the MDR-1 (P-glycoprotein) gene expression by protein kinase C agonists
    • Chaudary PM. Roninson IB 1992 Activation of the MDR-1 (P-glycoprotein) gene expression by protein kinase C agonists. Oncol Res 4: 281-290
    • (1992) Oncol Res , vol.4 , pp. 281-290
    • Chaudary, P.M.1    Roninson, I.B.2
  • 21
    • 0025322402 scopus 로고
    • Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein
    • Chen YN, Mickley LA, Schwartz AM, Action EM, Hwang H. Fojo AT 1990 Characterization of adriamycin-resistant human breast cancer cells which display overexpression of a novel resistance-related membrane protein. J Biol Chem 265: 10073-10080
    • (1990) J Biol Chem , vol.265 , pp. 10073-10080
    • Chen, Y.N.1    Mickley, L.A.2    Schwartz, A.M.3    Action, E.M.4    Hwang, H.5    Fojo, A.T.6
  • 22
    • 0029022589 scopus 로고
    • Identification of a sister-gene to P-glycoprotein
    • Childs S, Yeh RL, Georges E Ling V 1995 Identification of a sister-gene to P-glycoprotein. Cancer Res 55: 2029-2034
    • (1995) Cancer Res , vol.55 , pp. 2029-2034
    • Childs, S.1    Yeh, R.L.2    Georges, E.3    Ling, V.4
  • 23
    • 0027491276 scopus 로고
    • Evidence that ribonucleoprotein particles are localized to the nuclear pore complex
    • Chugani DC, Rome LH and Kederaha NL 1993 Evidence that ribonucleoprotein particles are localized to the nuclear pore complex. J Cell Sci 106: 23-29
    • (1993) J Cell Sci , vol.106 , pp. 23-29
    • Chugani, D.C.1    Rome, L.H.2    Kederaha, N.L.3
  • 31
    • 0031754926 scopus 로고    scopus 로고
    • Mechanisms of cellular anthracyclin resistance in childhood acute leukemia
    • Den Boer ML, Pieters R, Veerman A 1998b Mechanisms of cellular anthracyclin resistance in childhood acute leukemia. Leukemia 12: 1657-1670
    • (1998) Leukemia , vol.12 , pp. 1657-1670
    • Den Boer, M.L.1    Pieters, R.2    Veerman, A.3
  • 32
    • 0031833829 scopus 로고    scopus 로고
    • The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood leukemia
    • Den Boer ML, Pieters R, Kazemir KM, Janka-Schrauh GE, Henze G, Veerman AJ 1998c The modulating effect of PSC 833, cyclosporin A, verapamil and genistein on in vitro cytotoxicity and intracellular content of daunorubicin in childhood leukemia. Leukemia 12: 912-920
    • (1998) Leukemia , vol.12 , pp. 912-920
    • Den Boer, M.L.1    Pieters, R.2    Kazemir, K.M.3    Janka-Schrauh, G.E.4    Henze, G.5    Veerman, A.J.6
  • 33
    • 0033040149 scopus 로고    scopus 로고
    • P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukemia: Results of a 6-year prospective study
    • Dhooge C, De Moerloose B, lauteys G. Kint J, Ferster A, De Bacquer D, Philippe J. Benoit 1999 P-glycoprotein is an independent prognostic factor predicting relapse in childhood acute lymphoblastic leukemia: results of a 6-year prospective study. Br J Haematol 105: 676-683
    • (1999) Br J Haematol , vol.105 , pp. 676-683
    • Dhooge, C.1    De Moerloose, B.2    Lauteys, G.3    Kint, J.4    Ferster, A.5    De Bacquer, D.6    Benoit, P.J.7
  • 34
    • 0027406387 scopus 로고
    • A novel 95 kilodalton membrane polypeptide associated with lung cancer drug resistance
    • Dayle LA, Kaufman SH, Fojo AT, Bailey CL, Gazdar AF 1993 A novel 95 kilodalton membrane polypeptide associated with lung cancer drug resistance. Lung Cancer 9: 317-326
    • (1993) Lung Cancer , vol.9 , pp. 317-326
    • Dayle, L.A.1    Kaufman, S.H.2    Fojo, A.T.3    Bailey, C.L.4    Gazdar, A.F.5
  • 35
    • 0029097796 scopus 로고
    • Characterization of a 95 kilodalton membrane glycoprotein associated with multidrug resistance
    • Doyle LA, Yong Ming GAO, Yang W. Ross DD 1995a Characterization of a 95 kilodalton membrane glycoprotein associated with multidrug resistance. Int J Cancer 62: 593-598
    • (1995) Int J Cancer , vol.62 , pp. 593-598
    • Doyle, L.A.1    Yong Ming, G.A.O.2    Yang, W.3    Ross, D.D.4
  • 36
  • 37
    • 0029980046 scopus 로고    scopus 로고
    • H19gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein
    • Doyle LA, Yang W, Rishi AK, Gao Y, Ross DD 1996 H19gene overexpression in atypical multidrug-resistant cells associated with expression of a 95-kilodalton membrane glycoprotein. Cancer Res 56: 2904-2907
    • (1996) Cancer Res , vol.56 , pp. 2904-2907
    • Doyle, L.A.1    Yang, W.2    Rishi, A.K.3    Gao, Y.4    Ross, D.D.5
  • 38
    • 0022442075 scopus 로고
    • Correlation of drug sensitivity in vitro with clinical responses in childhood acute myeloid leukemia
    • Dow LW, Dahl GV, Kalwinxky DK, Miro J, Nash MB, Roberson PK 1986 Correlation of drug sensitivity in vitro with clinical responses in childhood acute myeloid leukemia. Blood 68: 400-405
    • (1986) Blood , vol.68 , pp. 400-405
    • Dow, L.W.1    Dahl, G.V.2    Kalwinxky, D.K.3    Miro, J.4    Nash, M.B.5    Roberson, P.K.6
  • 39
    • 0031870088 scopus 로고    scopus 로고
    • Multidrug resistance in aggresssive lymphoproliferative disorders of T- and natural-killer origin
    • Drenou B, Amiot L. Lamy T, Le Prise PY, Fauchet R 1998 Multidrug resistance in aggresssive lymphoproliferative disorders of T- and natural-killer origin. Leuk Lymphoma 30: 381-387
    • (1998) Leuk Lymphoma , vol.30 , pp. 381-387
    • Drenou, B.1    Amiot, L.2    Lamy, T.3    Le Prise, P.Y.4    Fauchet, R.5
  • 40
    • 0024329881 scopus 로고
    • The biochemistry of P-glycoprotein-mediated multidrug resistance
    • Endicott JA, Ling V 1990 The biochemistry of P-glycoprotein-mediated multidrug resistance. Ann Rev Biochem 58: 137-171
    • (1990) Ann Rev Biochem , vol.58 , pp. 137-171
    • Endicott, J.A.1    Ling, V.2
  • 42
    • 0030811596 scopus 로고    scopus 로고
    • Multidrug resistance-associated protein in acute myeloid leukemia: No impact on treatment outcome
    • Filipits M, Suchomel RW, Zochbauer M, Brunner R, Lechner K, Pirker R 1997 Multidrug resistance-associated protein in acute myeloid leukemia: no impact on treatment outcome. Clin Cancer Res 3: 1419-1425
    • (1997) Clin Cancer Res , vol.3 , pp. 1419-1425
    • Filipits, M.1    Suchomel, R.W.2    Zochbauer, M.3    Brunner, R.4    Lechner, K.5    Pirker, R.6
  • 44
    • 0028000734 scopus 로고
    • Immunochemical detection of the multidrug resistance-associated protein (MRP) in human multidrug-resistant tumor cells by monoclonal antibodies
    • Flens MJ, Izquirdo MA, Scheffer GL, Fritz JM, Meijer CJLM, Scheper RJ, Zaman GJR 1994 Immunochemical detection of the multidrug resistance-associated protein (MRP) in human multidrug-resistant tumor cells by monoclonal antibodies. Cancer Res 54: 4557-4563
    • (1994) Cancer Res , vol.54 , pp. 4557-4563
    • Flens, M.J.1    Izquirdo, M.A.2    Scheffer, G.L.3    Fritz, J.M.4    Meijer, C.J.L.M.5    Scheper, R.J.6    Zaman, G.J.R.7
  • 46
    • 0028631897 scopus 로고
    • Specificity and sensitivity of immunocyto-chemistry for detecting P-glycoprotein in haematologic malignancies
    • Gala JL, Lachlan JM, Belt DR, Michaux JL, Ma DDF 1994 Specificity and sensitivity of immunocyto-chemistry for detecting P-glycoprotein in haematologic malignancies. J Clin Pathol 47: 619-624
    • (1994) J Clin Pathol , vol.47 , pp. 619-624
    • Gala, J.L.1    Lachlan, J.M.2    Belt, D.R.3    Michaux, J.L.4    Ma, D.D.F.5
  • 47
    • 0003266942 scopus 로고    scopus 로고
    • Functional mdr-1 expression in adult acute lymphoblastic leukemia (ALL)
    • Gazitt Y, Lee DY, Wang ME, Boldt DH 1998 Functional mdr-1 expression in adult acute lymphoblastic leukemia (ALL). Blood 92: 676a
    • (1998) Blood , vol.92
    • Gazitt, Y.1    Lee, D.Y.2    Wang, M.E.3    Boldt, D.H.4
  • 49
  • 50
    • 0025141784 scopus 로고
    • Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies
    • Georges E, Bradley G, Gariepy J, Ling V 1990 Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies. Proc Natl Acad Sci USA 87: 152-156
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 152-156
    • Georges, E.1    Bradley, G.2    Gariepy, J.3    Ling, V.4
  • 51
    • 0027314191 scopus 로고
    • Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: Prognostic implications
    • Goasguen JE, Dossot JM, Fardel O, Le Mee F, Le Gall E, Leblay R, LePrise PY, Chaperreon J, Fauchet R 1993 Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood 81: 2394-2398
    • (1993) Blood , vol.81 , pp. 2394-2398
    • Goasguen, J.E.1    Dossot, J.M.2    Fardel, O.3    Le Mee, F.4    Le Gall, E.5    Leblay, R.6    LePrise, P.Y.7    Chaperreon, J.8    Fauchet, R.9
  • 53
    • 0028906671 scopus 로고
    • Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flowcytometry
    • Guerci A, Merlin JL, Missoum N, Feldman L, Marchal S, Witz F, Rose C, Guerci O 1995 Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flowcytometry. Blood 85: 2147-2153
    • (1995) Blood , vol.85 , pp. 2147-2153
    • Guerci, A.1    Merlin, J.L.2    Missoum, N.3    Feldman, L.4    Marchal, S.5    Witz, F.6    Rose, C.7    Guerci, O.8
  • 55
    • 0028600064 scopus 로고
    • Expression of the multidrug resistance-associated protein (MRP) in acute leukemia
    • Hart SM, Ganeshagunt K, Hoffbrand AV, Prentice HG, Mehta AB 1994 Expression of the multidrug resistance-associated protein (MRP) in acute leukemia. Leukemia 8: 2163-2168
    • (1994) Leukemia , vol.8 , pp. 2163-2168
    • Hart, S.M.1    Ganeshagunt, K.2    Hoffbrand, A.V.3    Prentice, H.G.4    Mehta, A.B.5
  • 57
    • 0029921733 scopus 로고    scopus 로고
    • The mdr phenotype in hematologic malignancies: Prognostic relevance and future perspectives
    • Hegewisch-Becker S and Hossfeld DK 1996 The mdr phenotype in hematologic malignancies: prognostic relevance and future perspectives. Ann Hematol 72: 105-117
    • (1996) Ann Hematol , vol.72 , pp. 105-117
    • Hegewisch-Becker, S.1    Hossfeld, D.K.2
  • 58
    • 0025341341 scopus 로고
    • Expression of mdr1 and mdr3 multidrug resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporin
    • Herwijer H, Sonneveld P, Baas F, Nooter K 1990 Expression of mdr1 and mdr3 multidrug resistance genes in human acute and chronic leukemias and association with stimulation of drug accumulation by cyclosporin. J Natl Cancer Inst 28: 1133-1140
    • (1990) J Natl Cancer Inst , vol.28 , pp. 1133-1140
    • Herwijer, H.1    Sonneveld, P.2    Baas, F.3    Nooter, K.4
  • 59
    • 0026621245 scopus 로고
    • ABC transporters - From microorganisms to man
    • Higgins CF 1992 ABC transporters - from microorganisms to man. Ann Rev Cell Biol 8: 67-113
    • (1992) Ann Rev Cell Biol , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 61
    • 0033060248 scopus 로고    scopus 로고
    • Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP
    • Hipfner DR, Qincheng M. Leslie EM, Gao M. Deeley RG, Cole SPC 1999 Monoclonal antibodies that inhibit the transport function of the 190-kDa multidrug resistance protein, MRP. J Biol Chem 274: 15420-15426
    • (1999) J Biol Chem , vol.274 , pp. 15420-15426
    • Hipfner, D.R.1    Qincheng, M.2    Leslie, E.M.3    Gao, M.4    Deeley, R.G.5    Cole, S.P.C.6
  • 62
    • 0031839226 scopus 로고    scopus 로고
    • Parallel functional and immunolocgical detection of human multidrug resistance proteins, P-glycoprotein and MRP1
    • Hollo Z, Homolya L, Hegedus T, Muller M, Szakacs G, Jakab K, Antal F, Sarkadi B 1998 Parallel functional and immunolocgical detection of human multidrug resistance proteins, P-glycoprotein and MRP1. Anticancer Res 18: 2981-2988
    • (1998) Anticancer Res , vol.18 , pp. 2981-2988
    • Hollo, Z.1    Homolya, L.2    Hegedus, T.3    Muller, M.4    Szakacs, G.5    Jakab, K.6    Antal, F.7    Sarkadi, B.8
  • 63
    • 0024566666 scopus 로고
    • Multidrug resistance in haemopoietic cell lines, myelodysplastic syndromes and acute myeloblastic leukemia
    • Holmes J, Jacobs A, Carter G, Janowska-Wieczorek A, Padua RA 1989 Multidrug resistance in haemopoietic cell lines, myelodysplastic syndromes and acute myeloblastic leukemia. Br J Haematol 72: 40-44
    • (1989) Br J Haematol , vol.72 , pp. 40-44
    • Holmes, J.1    Jacobs, A.2    Carter, G.3    Janowska-Wieczorek, A.4    Padua, R.A.5
  • 64
    • 0025979232 scopus 로고
    • Correlation of mdr status with clinical outcome in patients with acute myeloblastic leukemia
    • Holmes JA, WestRR, Whittaker JA, Jacobs A 1991 Correlation of mdr status with clinical outcome in patients with acute myeloblastic leukemia. Br J Haematol 77: 130-131
    • (1991) Br J Haematol , vol.77 , pp. 130-131
    • Holmes, J.A.1    West, R.R.2    Whittaker, J.A.3    Jacobs, A.4
  • 65
    • 0028032146 scopus 로고
    • The effect of MDR-1 gene expression on outcome in acute myeloid leukemia
    • Holmes JA and West RR 1994 The effect of MDR-1 gene expression on outcome in acute myeloid leukemia. Br J Cancer 69: 382-384
    • (1994) Br J Cancer , vol.69 , pp. 382-384
    • Holmes, J.A.1    West, R.R.2
  • 66
    • 0030984290 scopus 로고    scopus 로고
    • In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia
    • Hongo T, Yajima S, Sakurai M, Horikoshi Y, Hanada R 1997 In vitro drug sensitivity testing can predict induction failure and early relapse of childhood acute lymphoblastic leukemia. Blood 89: 2959-2965
    • (1997) Blood , vol.89 , pp. 2959-2965
    • Hongo, T.1    Yajima, S.2    Sakurai, M.3    Horikoshi, Y.4    Hanada, R.5
  • 67
    • 0031045308 scopus 로고    scopus 로고
    • Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells
    • Huang Y, Ibrado AM, Reed JC, Bullock G, Ray S, Tang C, Bhalla K 1997 Co-expression of several molecular mechanisms of multidrug resistance and their significance for paclitaxel cytotoxicity in human AML HL-60 cells. Leukemia 11: 253-257
    • (1997) Leukemia , vol.11 , pp. 253-257
    • Huang, Y.1    Ibrado, A.M.2    Reed, J.C.3    Bullock, G.4    Ray, S.5    Tang, C.6    Bhalla, K.7
  • 70
    • 0028133074 scopus 로고
    • Expression of P-glycoprotein in de novo acute myelogeneous leukemia at initial diagnosis: Results of molecular and functional assays, and correlation with treatment outcome
    • Ino T, Miyazaki H, Isogai M, Nomura T, Tsuzuki M, Tsuruo T, Ezaki K, Hirano M 1994 Expression of P-glycoprotein in de novo acute myelogeneous leukemia at initial diagnosis: results of molecular and functional assays, and correlation with treatment outcome. Leukemia 8: 1492-1497
    • (1994) Leukemia , vol.8 , pp. 1492-1497
    • Ino, T.1    Miyazaki, H.2    Isogai, M.3    Nomura, T.4    Tsuzuki, M.5    Tsuruo, T.6    Ezaki, K.7    Hirano, M.8
  • 71
    • 0011158775 scopus 로고
    • Detection of mdr1 gene expression using polymerase chain reaction (PCR) in childhood acute lymphoblastic leukemia (ALL) at diagnosis
    • Ivy SP, Smith JK, Speciale A. Sather H, Hammond GD, Reaman GH 1992 Detection of mdr1 gene expression using polymerase chain reaction (PCR) in childhood acute lymphoblastic leukemia (ALL) at diagnosis. Proc Am Assoc Cancer Res 33: 473a
    • (1992) Proc Am Assoc Cancer Res , vol.33
    • Ivy, S.P.1    Smith, J.K.2    Speciale, A.3    Sather, H.4    Hammond, G.D.5    Reaman, G.H.6
  • 72
    • 0002587009 scopus 로고
    • The prognostic significance of MDR1 gen expression at diagnosis in childhood acute lymphoblastic leukemia
    • Ivy SP, Sather HN, Hammond GD, Reaman GH 1993 The prognostic significance of MDR1 gen expression at diagnosis in childhood acute lymphoblastic leukemia. Pediatr Res 33: 141a
    • (1993) Pediatr Res , vol.33
    • Ivy, S.P.1    Sather, H.N.2    Hammond, G.D.3    Reaman, G.H.4
  • 73
    • 0029901696 scopus 로고    scopus 로고
    • Correlation of P-glycoprotein expression and function in childhood acute leukemia
    • Ivy SP, Olhefsky, Taylor BJ, Patel KM, Reaman GH 1996 Correlation of P-glycoprotein expression and function in childhood acute leukemia. Blood 88: 309-318
    • (1996) Blood , vol.88 , pp. 309-318
    • Ivy, S.P.1    Olhefsky2    Taylor, B.J.3    Patel, K.M.4    Reaman, G.H.5
  • 75
    • 0028001416 scopus 로고
    • ATP-dependent transport of gluthatione S-conjugates by the multidrug resistance-associated protein
    • Jedlitschky G, Leier I, Buchholz U, Center M, Keppler D 1994 ATP-dependent transport of gluthatione S-conjugates by the multidrug resistance-associated protein. Cancer Res 54: 4833-4836
    • (1994) Cancer Res , vol.54 , pp. 4833-4836
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Center, M.4    Keppler, D.5
  • 76
    • 0030063480 scopus 로고    scopus 로고
    • Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky G, Leier I, Buchholz U, Barnouin K, Keppler D 1996 Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump. Cancer Res 56: 988-994
    • (1996) Cancer Res , vol.56 , pp. 988-994
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Barnouin, K.4    Keppler, D.5
  • 77
    • 0027432181 scopus 로고
    • Prognostic factors in elderly patients with acute myeloid leukemia: Development of a model to predict survival
    • Johnson PRE, Hunt LP, Liu JA 1993 Prognostic factors in elderly patients with acute myeloid leukemia: development of a model to predict survival. Br J Haematol 85: 300-306
    • (1993) Br J Haematol , vol.85 , pp. 300-306
    • Johnson, P.R.E.1    Hunt, L.P.2    Liu, J.A.3
  • 80
    • 0031735836 scopus 로고    scopus 로고
    • In acute myeloid leukemia, co-expression of at least two proteins, including P-glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and the heat-shock protein 27, is predictive of the response to induction chemotherapy
    • Kasimir-Bauer S, Ottinger H, Meusers P, Beelen DW, Brittinger G, Seeber S, Scheulen ME 1998 In acute myeloid leukemia, co-expression of at least two proteins, including P-glycoprotein, the multidrug resistance-related protein, bcl-2, mutant p53, and the heat-shock protein 27, is predictive of the response to induction chemotherapy. Exp Hematol 26: 1111-1117
    • (1998) Exp Hematol , vol.26 , pp. 1111-1117
    • Kasimir-Bauer, S.1    Ottinger, H.2    Meusers, P.3    Beelen, D.W.4    Brittinger, G.5    Seeber, S.6    Scheulen, M.E.7
  • 84
  • 85
    • 0030841332 scopus 로고    scopus 로고
    • Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5. Homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
    • Kool M, De Haas, Scheffer GL, Scheper RJ, Van Eijk MJT, Juijn JA, Baas F, Borst P 1997 Analysis of expression of cMOAT (MRP2), MRP3, MRP4 and MRP5. Homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Cancer Res 57: 3537-3547
    • (1997) Cancer Res , vol.57 , pp. 3537-3547
    • De Haas, K.M.1    Scheffer, G.L.2    Scheper, R.J.3    Van Eijk, M.J.T.4    Juijn, J.A.5    Baas, F.6    Borst, P.7
  • 88
    • 0030016285 scopus 로고    scopus 로고
    • Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone marrow haemopoietic cells
    • Legrand O, Perrot J, Tang R, Siminin G, Gurbuxani S, Zittoun R, Marie JP 1996 Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone marrow haemopoietic cells. Br J Haematol 94: 23-33
    • (1996) Br J Haematol , vol.94 , pp. 23-33
    • Legrand, O.1    Perrot, J.2    Tang, R.3    Siminin, G.4    Gurbuxani, S.5    Zittoun, R.6    Marie, J.P.7
  • 89
    • 0004991905 scopus 로고    scopus 로고
    • Comparison of MDR1, MRP, and LRP expression with in vitro drug sensitivity and in vivo response to treatment in fresh blast cells from adult acute myeloid leukemia
    • Legrand O, Siminon G, Zittoun R, Marie JP 1997 Comparison of MDR1, MRP, and LRP expression with in vitro drug sensitivity and in vivo response to treatment in fresh blast cells from adult acute myeloid leukemia. Blood 90: 180a
    • (1997) Blood , vol.90
    • Legrand, O.1    Siminon, G.2    Zittoun, R.3    Marie, J.P.4
  • 90
    • 0031664606 scopus 로고    scopus 로고
    • Lung resistance protein (LRP) gene expression in adult acute myeloid leukemia: A critical evaluation by three techniques
    • Legrand O, Simonin G, Zittoun R, Marie JP 1998a Lung resistance protein (LRP) gene expression in adult acute myeloid leukemia: a critical evaluation by three techniques. Leukemia 12: 1367-1374
    • (1998) Leukemia , vol.12 , pp. 1367-1374
    • Legrand, O.1    Simonin, G.2    Zittoun, R.3    Marie, J.P.4
  • 91
    • 0031827404 scopus 로고    scopus 로고
    • Both P-gp and MRP contribute to drug resistance in AML
    • Legrand O, Simonin G. Zittoun R, Marie JP 1998b Both P-gp and MRP contribute to drug resistance in AML. Leukemia 12: 1327-1328
    • (1998) Leukemia , vol.12 , pp. 1327-1328
    • Legrand, O.1    Simonin, G.2    Zittoun, R.3    Marie, J.P.4
  • 92
    • 0031864247 scopus 로고    scopus 로고
    • Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients
    • Legrand O, Simonin G, Perrot JY, Zittoun R, Marie JP 1998c Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients. Blood 91: 4480-4488
    • (1998) Blood , vol.91 , pp. 4480-4488
    • Legrand, O.1    Simonin, G.2    Perrot, J.Y.3    Zittoun, R.4    Marie, J.P.5
  • 93
    • 0032935220 scopus 로고    scopus 로고
    • Role of MRP1 in multidrug resistance in acute myeloid leukemia
    • Legrand O, Zittoun R, Marie JP 1999 Role of MRP1 in multidrug resistance in acute myeloid leukemia. Leukemia 13: 578-584
    • (1999) Leukemia , vol.13 , pp. 578-584
    • Legrand, O.1    Zittoun, R.2    Marie, J.P.3
  • 94
    • 0029096486 scopus 로고
    • Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flowcytometry: Identification of discordant MDR-/Efflux+ and MDR+/ Efflux- cases
    • Leith CP, Chen IM, Kopecky KJ, Appelbaum FR, Head DR, Godwin JE, Weick JK, Willman CL 1995 Correlation of multidrug resistance (MDR1) protein expression with functional dye/drug efflux in acute myeloid leukemia by multiparameter flowcytometry: identification of discordant MDR-/Efflux+ and MDR+/ Efflux- cases. Blood 86: 2329-2342
    • (1995) Blood , vol.86 , pp. 2329-2342
    • Leith, C.P.1    Chen, I.M.2    Kopecky, K.J.3    Appelbaum, F.R.4    Head, D.R.5    Godwin, J.E.6    Weick, J.K.7    Willman, C.L.8
  • 95
    • 0345537497 scopus 로고    scopus 로고
    • Frequency and clinical significance of expression of the multidrug resistance proteins MDR1, MRP1 and LRP in acute myeloid leukemia patients less than 65 years old
    • Leith CP, Kopecky KJ, Chen IM, Slovak M, Head DR, Weick J, Appelbaum FR, Willman CL 1997 Frequency and clinical significance of expression of the multidrug resistance proteins MDR1, MRP1 and LRP in acute myeloid leukemia patients less than 65 years old. Blood 90: 389a
    • (1997) Blood , vol.90
    • Leith, C.P.1    Kopecky, K.J.2    Chen, I.M.3    Slovak, M.4    Head, D.R.5    Weick, J.6    Appelbaum, F.R.7    Willman, C.L.8
  • 96
    • 0032413898 scopus 로고    scopus 로고
    • Multidrug resistance in leukemia
    • Leith C 1998 Multidrug resistance in leukemia. Curr Opin Hematol 5: 287-291
    • (1998) Curr Opin Hematol , vol.5 , pp. 287-291
    • Leith, C.1
  • 97
    • 0031838229 scopus 로고    scopus 로고
    • Expression of lung resistance protein and correlation with other drug resistance proteins and outcome in myelodysplatic syndromes
    • Lepelley P, Poulain S, Grardrel N, Peudhomme C, Cosson A, Fenaux P 1998 Expression of lung resistance protein and correlation with other drug resistance proteins and outcome in myelodysplatic syndromes. Leuk Lymphoma 29: 547-551
    • (1998) Leuk Lymphoma , vol.29 , pp. 547-551
    • Lepelley, P.1    Poulain, S.2    Grardrel, N.3    Peudhomme, C.4    Cosson, A.5    Fenaux, P.6
  • 99
    • 0029963038 scopus 로고    scopus 로고
    • Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia
    • List AF 1996a Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia. Leukemia 10: 937-942
    • (1996) Leukemia , vol.10 , pp. 937-942
    • List, A.F.1
  • 101
    • 0030770522 scopus 로고    scopus 로고
    • Five putative drug resistance parameters (MDR1/P-glycoprotem, MDR-1 associated protein, gluthatione-S-transferase, bcl-2 and topoisomerase 11 alpha) in 57 newly diagnosed acute myeloid leukemias
    • Swiss Group for Clinical Cancer Research (SAKK)
    • Lohri A, Van Hille B, Bacchi M, Fopp M, Joncourt F, Reuter J, Cerny T, Fey MF, Herrmann R 1997a Five putative drug resistance parameters (MDR1/P-glycoprotem, MDR-1 associated protein, gluthatione-S-transferase, bcl-2 and topoisomerase 11 alpha) in 57 newly diagnosed acute myeloid leukemias. Swiss Group for Clinical Cancer Research (SAKK). Eur J Haematol 59: 206-215
    • (1997) Eur J Haematol , vol.59 , pp. 206-215
    • Lohri, A.1    Van Hille, B.2    Bacchi, M.3    Fopp, M.4    Joncourt, F.5    Reuter, J.6    Cerny, T.7    Fey, M.F.8    Herrmann, R.9
  • 102
    • 0030925196 scopus 로고    scopus 로고
    • MRNA expression, measured by quantitative reverse transcriptase polymerase chain reaction, of five putative drug resistance parameters, in normal and leukemic peripheral blood and bone marrow
    • Lohri A, Van Hille B, Reuter J, Tichelli A, Herrmann R 1997b mRNA expression, measured by quantitative reverse transcriptase polymerase chain reaction, of five putative drug resistance parameters, in normal and leukemic peripheral blood and bone marrow. Acta Haematol 98: 1-7
    • (1997) Acta Haematol , vol.98 , pp. 1-7
    • Lohri, A.1    Van Hille, B.2    Reuter, J.3    Tichelli, A.4    Herrmann, R.5
  • 103
    • 0029803103 scopus 로고    scopus 로고
    • The anthracyclin resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line
    • Longhurst TJ, O'Neill GM, Harvie RM, Davey RA 1996. The anthracyclin resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line. Br J Cancer 74: 1331-1335
    • (1996) Br J Cancer , vol.74 , pp. 1331-1335
    • Longhurst, T.J.1    O'Neill, G.M.2    Harvie, R.M.3    Davey, R.A.4
  • 104
    • 0031975817 scopus 로고    scopus 로고
    • Resistance to chemotherapy in acute leukemia
    • Lowenherg B, Sonneveld P 1998 Resistance to chemotherapy in acute leukemia. Curr Opinion Oncol 10: 31-35
    • (1998) Curr Opinion Oncol , vol.10 , pp. 31-35
    • Lowenherg, B.1    Sonneveld, P.2
  • 107
    • 0025914062 scopus 로고
    • Multidrug resistance (mdr-1) gene expression in adult acute leukemias: Correlation with treatment outcome and in vitro drug sensitivity
    • Marie JP, Zittoun R, Sikic BI 1991 Multidrug resistance (mdr-1) gene expression in adult acute leukemias: correlation with treatment outcome and in vitro drug sensitivity. Blood 78: 586-592
    • (1991) Blood , vol.78 , pp. 586-592
    • Marie, J.P.1    Zittoun, R.2    Sikic, B.I.3
  • 108
    • 0027305734 scopus 로고
    • Daunorubicin uptake by leukemic cells: Correlations with treatment outcome and mdr-1 expression
    • Marie JP, Faussat-Suberville AM, Zhou D, Zittoun R 1993a Daunorubicin uptake by leukemic cells: correlations with treatment outcome and mdr-1 expression. Leukemia 7: 825-831
    • (1993) Leukemia , vol.7 , pp. 825-831
    • Marie, J.P.1    Faussat-Suberville, A.M.2    Zhou, D.3    Zittoun, R.4
  • 111
    • 0342492607 scopus 로고    scopus 로고
    • Debate round-table: Phenotyptic and genotypic analyses of multidrug resistance (MDR) in clinical hospital practice
    • Marie JP 1997 Debate round-table: phenotyptic and genotypic analyses of multidrug resistance (MDR) in clinical hospital practice. Leukemia 11: 1063-1186
    • (1997) Leukemia , vol.11 , pp. 1063-1186
    • Marie, J.P.1
  • 112
    • 0030667219 scopus 로고    scopus 로고
    • Functional expression of MDR-1 in acute myeloid leukemia: Correlation with the cinical-biological, immunophenotypical, and prognostic disease characteristics
    • Martinez A, San Miguel JF, Valverde B, Barez A, Moro MJ, Garcia-Marcos MA, Perez-Simon JA, Vidriales, Orfao A 1998 Functional expression of MDR-1 in acute myeloid leukemia: correlation with the cinical-biological, immunophenotypical, and prognostic disease characteristics Ann Hematol 75: 81-86
    • (1998) Ann Hematol , vol.75 , pp. 81-86
    • Martinez, A.1    San Miguel, J.F.2    Valverde, B.3    Barez, A.4    Moro, M.J.5    Garcia-Marcos, M.A.6    Perez-Simon, J.A.7    Vidriales, O.A.8
  • 113
    • 0024340285 scopus 로고
    • Effects of verapamil on the cellular accumulation of daunorubicin in blast cells and on the chemo-sensitivity of leukemic blast progenitors in acute myelogeneous leukemia
    • Maruyama Y, Murohashi I, Nara N, Aoki N 1989 Effects of Verapamil on the cellular accumulation of daunorubicin in blast cells and on the chemo-sensitivity of leukemic blast progenitors in acute myelogeneous leukemia. Br J Haematol 72: 357-362
    • (1989) Br J Haematol , vol.72 , pp. 357-362
    • Maruyama, Y.1    Murohashi, I.2    Nara, N.3    Aoki, N.4
  • 114
    • 0031782307 scopus 로고    scopus 로고
    • Influence of SDZ-PSC833 on daunomycin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukemia
    • Merlin JL, Guerci A, Marchal S, Bour C, Colosetti P, Kataki A, Guerci O 1998 Influence of SDZ-PSC833 on daunomycin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukemia. Br J Haematol 103: 480-487
    • (1998) Br J Haematol , vol.103 , pp. 480-487
    • Merlin, J.L.1    Guerci, A.2    Marchal, S.3    Bour, C.4    Colosetti, P.5    Kataki, A.6    Guerci, O.7
  • 117
    • 0032911283 scopus 로고    scopus 로고
    • P-glycoprotein, lung resistance-related protein and multidrug resistance associated protein in de novo acute non-lymphocytic leukaemias: Biological and clinical implications
    • Michieli M, Damiani D, Ermacora A, Musolini P, Raspadori D, Visani G, Scheper RJ, Baccarani M 1999 P-glycoprotein, lung resistance-related protein and multidrug resistance associated protein in de novo acute non-lymphocytic leukaemias: biological and clinical implications. Br J Haematol 104: 328-335
    • (1999) Br J Haematol , vol.104 , pp. 328-335
    • Michieli, M.1    Damiani, D.2    Ermacora, A.3    Musolini, P.4    Raspadori, D.5    Visani, G.6    Scheper, R.J.7    Baccarani, M.8
  • 118
    • 0027374118 scopus 로고
    • Expression of MDR1 gene in acute leukemia cells: Association with CD7 positive acute myeloblastic leukemia/acute lymphoblastic leukemia
    • Miwa H, Kita K, Morita N, Takakura N, Ohishim K, Mahmud N, Kageyamu S, Fukumoto M, Shirakawa S 1993 Expression of MDR1 gene in acute leukemia cells: association with CD7 positive acute myeloblastic leukemia/acute lymphoblastic leukemia. Blood 82: 3445-2451
    • (1993) Blood , vol.82 , pp. 3445-12451
    • Miwa, H.1    Kita, K.2    Morita, N.3    Takakura, N.4    Ohishim, K.5    Mahmud, N.6    Kageyamu, S.7    Fukumoto, M.8    Shirakawa, S.9
  • 119
    • 0025728859 scopus 로고
    • Detection of multidrug-resistant protein, P-glycoprotein in childhood leukaemia and lymphoma
    • Mizuno Y, Hara T, Nagata M, Tawa A, Tsuruo T, Ueda K 1991 Detection of multidrug-resistant protein, P-glycoprotein in childhood leukaemia and lymphoma. Eur J Pediatr 150: 416-418
    • (1991) Eur J Pediatr , vol.150 , pp. 416-418
    • Mizuno, Y.1    Hara, T.2    Nagata, M.3    Tawa, A.4    Tsuruo, T.5    Ueda, K.6
  • 120
    • 0027239749 scopus 로고
    • Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter
    • Neefjes JJ, Momburg F, Hämmerling GJ 1993 Selective and ATP-dependent translocation of peptides by the MHC-encoded transporter. Science 261: 769-771
    • (1993) Science , vol.261 , pp. 769-771
    • Neefjes, J.J.1    Momburg, F.2    Hämmerling, G.J.3
  • 124
    • 0030744250 scopus 로고    scopus 로고
    • Multidrug resistance in acute leukemia: A comparison of different diagnostic methods
    • Pall G, Spitaler M, Hofman J, Thaler J, Ludescher C 1997 Multidrug resistance in acute leukemia: a comparison of different diagnostic methods. Leukemia 11: 1067-1072
    • (1997) Leukemia , vol.11 , pp. 1067-1072
    • Pall, G.1    Spitaler, M.2    Hofman, J.3    Thaler, J.4    Ludescher, C.5
  • 125
    • 0032956842 scopus 로고    scopus 로고
    • Use of standardized flow-cytometric determinants of multidrug resistance to analyse response to remission induction chemotherapy in patients with acute myeloblastic leukemia
    • Pallis M, Turzanski J, Wheatley K, Langabeer S, Burmett AK, Russell NH 1999 Use of standardized flow-cytometric determinants of multidrug resistance to analyse response to remission induction chemotherapy in patients with acute myeloblastic leukemia. Br J Haematol 104: 258-265
    • (1999) Br J Haematol , vol.104 , pp. 258-265
    • Pallis, M.1    Turzanski, J.2    Wheatley, K.3    Langabeer, S.4    Burmett, A.K.5    Russell, N.H.6
  • 126
    • 0029979819 scopus 로고    scopus 로고
    • ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter
    • Paul S, Breuninger LA, Tew KD, Shen H, Kruh GD 1996 ATP-dependent uptake of natural product cytotoxic drugs by membrane vesicles establishes MRP as a broad specificity transporter. Proc Natl Acad Sci 93: 6929-6934
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 6929-6934
    • Paul, S.1    Breuninger, L.A.2    Tew, K.D.3    Shen, H.4    Kruh, G.D.5
  • 127
    • 0025870820 scopus 로고
    • Correlation of in vitro drug resistance assessed by the MTT assay with long-term clinical outcome in childhood acute lymphoblastic leukemia
    • Pieters R, Huismans DR, Loonen AH, Hählen K, Van der Does-van den Berg A, Van Wering ER, Veerman AJP 1991 Correlation of in vitro drug resistance assessed by the MTT assay with long-term clinical outcome in childhood acute lymphoblastic leukemia. Lancet 338: 399-403
    • (1991) Lancet , vol.338 , pp. 399-403
    • Pieters, R.1    Huismans, D.R.2    Loonen, A.H.3    Hählen, K.4    Van Der Does-Van Den Berg, A.5    Van Wering, E.R.6    Veerman, A.J.P.7
  • 128
    • 0026553235 scopus 로고
    • Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukemia
    • Pieters R, Hongo T, Loonen AH, Huismans DR, Broxterman HJ, Hählen K, Veerman AJP 1992 Different types of non-P-glycoprotein mediated multiple drug resistance in children with relapsed acute lymphoblastic leukemia. Br J Cancer 65: 691-697
    • (1992) Br J Cancer , vol.65 , pp. 691-697
    • Pieters, R.1    Hongo, T.2    Loonen, A.H.3    Huismans, D.R.4    Broxterman, H.J.5    Hählen, K.6    Veerman, A.J.P.7
  • 129
    • 0030889437 scopus 로고    scopus 로고
    • Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia
    • Pieters R, Klumper E, Kaspers GJL, Veerman AJP 1997 Everything you always wanted to know about cellular drug resistance in childhood acute lymphoblastic leukemia. Crit Rev Oncol Hematol 25: 11-26
    • (1997) Crit Rev Oncol Hematol , vol.25 , pp. 11-26
    • Pieters, R.1    Klumper, E.2    Kaspers, G.J.L.3    Veerman, A.J.P.4
  • 131
    • 0031717981 scopus 로고    scopus 로고
    • Relation between age, immunophenotype, and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - Implications for treatment of infants
    • Pieters R, Den Boer ML, Durian M, Janka-Schaub GE, Schmiegelow K, Kaspers GJL, Van Wering ER, Veerman AJP 1998b Relation between age, immunophenotype, and in vitro drug resistance in 395 children with acute lymphoblastic leukemia - implications for treatment of infants. Leukemia 12: 1344-1348
    • (1998) Leukemia , vol.12 , pp. 1344-1348
    • Pieters, R.1    Den Boer, M.L.2    Durian, M.3    Janka-Schaub, G.E.4    Schmiegelow, K.5    Kaspers, G.J.L.6    Van Wering, E.R.7    Veerman, A.J.P.8
  • 134
    • 0032006691 scopus 로고    scopus 로고
    • Lung-resistance-related protein expression is a negative predictive factor for response to conventional low but not to intensified dose alkylating chemotherapy in multiple myeloma
    • Raaijmakers HG, Izquirdo MA, Lokhorst HM, de Leeuw C, Belien JA, Bloem AC, Dekker AW, Scheper RJ, Sonneveld P 1998 Lung-resistance-related protein expression is a negative predictive factor for response to conventional low but not to intensified dose alkylating chemotherapy in multiple myeloma. Blood 91: 1029-1036
    • (1998) Blood , vol.91 , pp. 1029-1036
    • Raaijmakers, H.G.1    Izquirdo, M.A.2    Lokhorst, H.M.3    De Leeuw, C.4    Belien, J.A.5    Bloem, A.C.6    Dekker, A.W.7    Scheper, R.J.8    Sonneveld, P.9
  • 135
    • 0025167527 scopus 로고
    • Modulation of multidrug resistance by verapamil or mdr-1 anti-sense oligodeoxy-nucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human (LoVo) cell line
    • Rivoltini L, Colombo MP, Supino R, Ballinari D, Tsuruo T, Parmiani G 1990 Modulation of multidrug resistance by verapamil or mdr-1 anti-sense oligodeoxy-nucleotide does not change the high susceptibility to lymphokine-activated killers in mdr-resistant human (LoVo) cell line. Int J Cancer 46: 727-732
    • (1990) Int J Cancer , vol.46 , pp. 727-732
    • Rivoltini, L.1    Colombo, M.P.2    Supino, R.3    Ballinari, D.4    Tsuruo, T.5    Parmiani, G.6
  • 137
    • 0029074529 scopus 로고
    • Multidrug resistance: Locked in the vault?
    • Rome LH 1995 Multidrug resistance: locked in the vault? Nature Med 1: 527
    • (1995) Nature Med , vol.1 , pp. 527
    • Rome, L.H.1
  • 138
    • 0027199122 scopus 로고
    • Enhancement of daunorubicin accumulation, retention, and cytotoxicity by verapamil or cyclosporin A in blast cells from patients with previously untreated acute myeloid leukemia
    • Ross DD, Wooten PJ, Sridhara R, Ordonez JV, Lee EJ, Schiffer CA 1993 Enhancement of daunorubicin accumulation, retention, and cytotoxicity by verapamil or cyclosporin A in blast cells from patients with previously untreated acute myeloid leukemia. Blood 82: 1288-1299
    • (1993) Blood , vol.82 , pp. 1288-1299
    • Ross, D.D.1    Wooten, P.J.2    Sridhara, R.3    Ordonez, J.V.4    Lee, E.J.5    Schiffer, C.A.6
  • 139
  • 140
    • 0343916919 scopus 로고    scopus 로고
    • Expression of breast cancer resistance protein (BCRP) in blast cells from patients with acute myeloid leukemia
    • Ross DD, Karp J, Yang W, Gao Y, Abruzzo LV, Doyle LA 1998 Expression of breast cancer resistance protein (BCRP) in blast cells from patients with acute myeloid leukemia. Blood 93: 386a
    • (1998) Blood , vol.93
    • Ross, D.D.1    Karp, J.2    Yang, W.3    Gao, Y.4    Abruzzo, L.V.5    Doyle, L.A.6
  • 144
    • 0025565954 scopus 로고
    • Staurosporin, a potent inhibitor of C-kinase, enhances drug accumulation in multi-drug resistant cells
    • Sato W, Yuas K, Naito M, Tsuruo T 1990b Staurosporin, a potent inhibitor of C-kinase, enhances drug accumulation in multi-drug resistant cells. Biochem Biophys Res Commun 173: 1252
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 1252
    • Sato, W.1    Yuas, K.2    Naito, M.3    Tsuruo, T.4
  • 146
    • 0028099650 scopus 로고
    • P-glycoprotein and gluthatione S-transferase p in childhood acute lymphoblastic leukemia: Prognostic implications
    • Sauerbrey A, Zintl F, Volm M 1994 P-glycoprotein and gluthatione S-transferase p in childhood acute lymphoblastic leukemia: Prognostic implications. Br J Cancer 70: 1144-1149
    • (1994) Br J Cancer , vol.70 , pp. 1144-1149
    • Sauerbrey, A.1    Zintl, F.2    Volm, M.3
  • 153
    • 0029609704 scopus 로고
    • Cell surface expression of the multidrug resistance P-glycoprotein (P-170) as detected by monoclonal antibody MRK-16 pediatric in acute myeloid leukemia fails to define a poor prognostic group
    • Sievers EL, Smith FO, Woods WG, Lee JW, Bleyer WA, Willman CL, Bernstein ID 1995 Cell surface expression of the multidrug resistance P-glycoprotein (P-170) as detected by monoclonal antibody MRK-16 pediatric in acute myeloid leukemia fails to define a poor prognostic group. Leukemia 9: 2042-2048
    • (1995) Leukemia , vol.9 , pp. 2042-2048
    • Sievers, E.L.1    Smith, F.O.2    Woods, W.G.3    Lee, J.W.4    Bleyer, W.A.5    Willman, C.L.6    Bernstein, I.D.7
  • 154
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon SM and Schindler M 1994 Cell biological mechanisms of multidrug resistance in tumors. Proc Natl Acad Sci USA 91: 3497-3504
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 155
    • 0029045777 scopus 로고
    • The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: Evidence that chromosome breakage plays a key role in MRP or LRP gene amplification
    • Slovak LS, Ho JP, Cole SPC, Deeley RG, Greenberger L, de Vries EGE, Broxterman HJ, Scheffer GL, Scheper RJ 1995 The LRP gene encoding a major vault protein associated with drug resistance maps proximal to MRP on chromosome 16: evidence that chromosome breakage plays a key role in MRP or LRP gene amplification. Cancer Res 55: 4214-4219
    • (1995) Cancer Res , vol.55 , pp. 4214-4219
    • Slovak, L.S.1    Ho, J.P.2    Cole, S.P.C.3    Deeley, R.G.4    Greenberger, L.5    De Vries, E.G.E.6    Broxterman, H.J.7    Scheffer, G.L.8    Scheper, R.J.9
  • 156
    • 0028081258 scopus 로고
    • Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemic cells
    • Slapak CA, Mizunuma N, Kufe DW 1994 Expression of the multidrug resistance associated protein and P-glycoprotein in doxorubicin-selected human myeloid leukemic cells. Blood 84: 3113-3121
    • (1994) Blood , vol.84 , pp. 3113-3121
    • Slapak, C.A.1    Mizunuma, N.2    Kufe, D.W.3
  • 157
    • 0022908210 scopus 로고
    • Prediction of remission induction in childhood acute myeloid leukemia
    • Smith PJ, Lihou MG 1986 Prediction of remission induction in childhood acute myeloid leukemia. Aust NZ J Med 16: 39-42
    • (1986) Aust NZ J Med , vol.16 , pp. 39-42
    • Smith, P.J.1    Lihou, M.G.2
  • 160
    • 0030825823 scopus 로고    scopus 로고
    • Inhibitors of multidrug resistance
    • Sonneveld P, Wiemer E 1997a Inhibitors of multidrug resistance. Curr Opin Oncol 9: 543-548
    • (1997) Curr Opin Oncol , vol.9 , pp. 543-548
    • Sonneveld, P.1    Wiemer, E.2
  • 161
    • 0030790531 scopus 로고    scopus 로고
    • Assays for the analysis of P-glycoprotein in acute myeloid leukemia and CD34 subsets of AML blasts
    • Sonneveld P, Wiemer E 1997b Assays for the analysis of P-glycoprotein in acute myeloid leukemia and CD34 subsets of AML blasts. Leukemia 11: 1160-1165
    • (1997) Leukemia , vol.11 , pp. 1160-1165
    • Sonneveld, P.1    Wiemer, E.2
  • 162
    • 85087234639 scopus 로고    scopus 로고
    • Prognostic value of cytogenetics and multidrug resistance (MDR1) in elderly patients with acute myeloid leukemia
    • Stasi R 1998 Prognostic value of cytogenetics and multidrug resistance (MDR1) in elderly patients with acute myeloid leukemia. Blood 92: 695-705
    • (1998) Blood , vol.92 , pp. 695-705
    • Stasi, R.1
  • 164
    • 0029877305 scopus 로고    scopus 로고
    • Expression of multidrug resistance P-glycoprotein in myeloid progenitor cells of different phenotype: Comparison between normal bone marrow cells and leukemia cells
    • Takeshita A, Shinjo K, Ohnishi K, Ohno R 1996 Expression of multidrug resistance P-glycoprotein in myeloid progenitor cells of different phenotype: comparison between normal bone marrow cells and leukemia cells. Br J Haematol 93: 18-21
    • (1996) Br J Haematol , vol.93 , pp. 18-21
    • Takeshita, A.1    Shinjo, K.2    Ohnishi, K.3    Ohno, R.4
  • 165
    • 0026721685 scopus 로고
    • Reversal of typical multidrug resistance by cyclosporin and its non-immunosuppressive SDZ PSC in Chinese Hamster Ovary cells expressing the mdr1 phenotype
    • Te Boekhorst PAW, Van Kapel J, Schoester M, Sonneveld P 1992 Reversal of typical multidrug resistance by cyclosporin and its non-immunosuppressive SDZ PSC in Chinese Hamster Ovary cells expressing the mdr1 phenotype. Cancer Chemother Pharmcol 30: 238-242
    • (1992) Cancer Chemother Pharmcol , vol.30 , pp. 238-242
    • Te Boekhorst, P.A.W.1    Van Kapel, J.2    Schoester, M.3    Sonneveld, P.4
  • 170
    • 0031744484 scopus 로고    scopus 로고
    • Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells
    • Van der Kolk D, de Vries EGE, Koning JA, VandenBerg E, Muller M, Vellenga E 1998 Activity and expression of the multidrug resistance proteins MRP1 and MRP2 in acute myeloid leukemia cells, tumor cell lines, and normal hematopoietic CD34+ peripheral blood cells. Clin Cancer Res 4: 1727-1736
    • (1998) Clin Cancer Res , vol.4 , pp. 1727-1736
    • Van Der Kolk, D.1    De Vries, E.G.E.2    Koning, J.A.3    Vandenberg, E.4    Muller, M.5    Vellenga, E.6
  • 171
    • 0029029449 scopus 로고
    • Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein
    • Versantvoort CHM, Broxterman HJ, Bagrij T, Scheper RJ, Twentyman PR 1995 Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein. Br J Cancer 72: 82-89
    • (1995) Br J Cancer , vol.72 , pp. 82-89
    • Versantvoort, C.H.M.1    Broxterman, H.J.2    Bagrij, T.3    Scheper, R.J.4    Twentyman, P.R.5
  • 172
    • 0030824146 scopus 로고    scopus 로고
    • Expression of lung-resistance protein (LRP) in initial and relapsed childhood acute lymphoblastic leukemia
    • Volm M, Stammler G, Zintl F, Koomägi R, Sauerbrey A 1997 Expression of lung-resistance protein (LRP) in initial and relapsed childhood acute lymphoblastic leukemia. Anticancer Drugs 8: 662-665
    • (1997) Anticancer Drugs , vol.8 , pp. 662-665
    • Volm, M.1    Stammler, G.2    Zintl, F.3    Koomägi, R.4    Sauerbrey, A.5
  • 173
    • 0031843013 scopus 로고    scopus 로고
    • Multidrug resistance and its reversal
    • Volm M 1998 Multidrug resistance and its reversal. Anticancer Res 18: 2905-2918
    • (1998) Anticancer Res , vol.18 , pp. 2905-2918
    • Volm, M.1
  • 174
    • 0032992844 scopus 로고    scopus 로고
    • Reversal of multidrug resistance
    • Vossebeld PJ, Sonneveld P 1999 Reversal of multidrug resistance. Blood Rev 13: 67-78
    • (1999) Blood Rev , vol.13 , pp. 67-78
    • Vossebeld, P.J.1    Sonneveld, P.2
  • 175
    • 0028895212 scopus 로고
    • Expression of the multidrug resistance P-glycoprotein in newly diagnosed adult lymphoblastic leukemia: Absence of correlation with response to treatment
    • Wattel E, Lepelley P, Meralt A, Sartiaux C, Baulers F, Jouet JP, Fenaux P 1995 Expression of the multidrug resistance P-glycoprotein in newly diagnosed adult lymphoblastic leukemia: absence of correlation with response to treatment. Leukemia 9: 1870-1874
    • (1995) Leukemia , vol.9 , pp. 1870-1874
    • Wattel, E.1    Lepelley, P.2    Meralt, A.3    Sartiaux, C.4    Baulers, F.5    Jouet, J.P.6    Fenaux, P.7
  • 176
    • 0346790755 scopus 로고    scopus 로고
    • Intracellular lozalisation and dynamics of the vault complex in non-Pgp multidrug resistant cell lines
    • Wiemer E, Schoester M, Sonneveld P 1998 Intracellular lozalisation and dynamics of the vault complex in non-Pgp multidrug resistant cell lines. Blood 92: 676a
    • (1998) Blood , vol.92
    • Wiemer, E.1    Schoester, M.2    Sonneveld, P.3
  • 177
    • 0031452589 scopus 로고    scopus 로고
    • The prognostic significance of the expression and function of multidrug resistance proteins in acute myeloid leukemia: Studies of the Southwest Oncology Group Leukemia Research Programm
    • Willman CL 1997 The prognostic significance of the expression and function of multidrug resistance proteins in acute myeloid leukemia: studies of the Southwest Oncology Group Leukemia Research Programm. Semin Hematol 34 (4 Suppl 5): 25-33
    • (1997) Semin Hematol , vol.34 , Issue.4 SUPPL. 5 , pp. 25-33
    • Willman, C.L.1
  • 178
    • 0028244591 scopus 로고
    • P-glycoprotein expression on acute myeloid leukaemia blast cells at diagnosis predicts response to chemotherapy and survival
    • Wood P, Burgess R, McGregor A, Liu Yin JA 1994 P-glycoprotein expression on acute myeloid leukaemia blast cells at diagnosis predicts response to chemotherapy and survival. Br J Haematol 87: 509-514
    • (1994) Br J Haematol , vol.87 , pp. 509-514
    • Wood, P.1    Burgess, R.2    McGregor, A.3    Liu Yin, J.A.4
  • 179
    • 0029922321 scopus 로고    scopus 로고
    • Levels of mdr1 and mrp mRNA in leucaemic cell populations from patients with acute myelocytic leucaemia are heterogenous and inversely correlated to cellular daunorubicin accumulation
    • Xu D, Knaust E, Pisa P, Palucka K, Lundeberg J, Arestrom I, Peterson C, Gruber A 1996 Levels of mdr1 and mrp mRNA in leucaemic cell populations from patients with acute myelocytic leucaemia are heterogenous and inversely correlated to cellular daunorubicin accumulation. Br J Haematol 92: 847-854
    • (1996) Br J Haematol , vol.92 , pp. 847-854
    • Xu, D.1    Knaust, E.2    Pisa, P.3    Palucka, K.4    Lundeberg, J.5    Arestrom, I.6    Peterson, C.7    Gruber, A.8
  • 181
    • 0026699910 scopus 로고
    • Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods
    • Zhou DC, Marie JP, Suberville AM, Zittoun R 1992 Relevance of mdr1 gene expression in acute myeloid leukemia and comparison of different diagnostic methods. Leukemia 6: 879-885
    • (1992) Leukemia , vol.6 , pp. 879-885
    • Zhou, D.C.1    Marie, J.P.2    Suberville, A.M.3    Zittoun, R.4
  • 182
    • 0028793942 scopus 로고
    • Expression of multidrug resistance-associated protein (MRP) and multidrug resistance genes (MDR1) genes in acute myeloid leukemia
    • Zhou DC, Zittoun R, Marie JP 1995 Expression of multidrug resistance-associated protein (MRP) and multidrug resistance genes (MDR1) genes in acute myeloid leukemia. Leukemia 9: 1661-1666
    • (1995) Leukemia , vol.9 , pp. 1661-1666
    • Zhou, D.C.1    Zittoun, R.2    Marie, J.P.3
  • 183
    • 0028178091 scopus 로고
    • P-glycoprotein expression as a favorable prognostic factor in acute myeloid leukemia
    • Zochbauer S, Gsur A, Brunner R, Kyrie PA, Lechner K, Pirker R 1994 P-glycoprotein expression as a favorable prognostic factor in acute myeloid leukemia. Leukemia 8: 974-977
    • (1994) Leukemia , vol.8 , pp. 974-977
    • Zochbauer, S.1    Gsur, A.2    Brunner, R.3    Kyrie, P.A.4    Lechner, K.5    Pirker, R.6


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