Identification of breast cancer resistant protein/mitoxantrone resistance/placenta-specific, ATP-binding cassette transporter as a transporter of NB-506 and J-107088, topoisomerase I inhibitors with an indolocarbazole structure

Cancer Research

Volumn 61, Issue 7, 2001, Pages 2827-2832

  Komatani, Hideya ^a   Kotani, Hidehito ^a   Hara, Yoshikazu ^a   Nakagawa, Rinako ^a   Matsumoto, Mami ^b   Arakawa, Hiroharu ^a   Nishimura, Susumu ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b BANYU PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; ABC TRANSPORTER; DNA TOPOISOMERASE INHIBITOR; EDOTECARIN; GENE PRODUCT; MITOXANTRONE; OLIGONUCLEOTIDE; PROTEIN BCRP; PROTEIN MXR; TOPOTECAN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BREAST CANCER; COLON CARCINOMA; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG STRUCTURE; FIBROBLAST CULTURE; GENE OVEREXPRESSION; GENETIC ANALYSIS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; TUMOR CELL LINE; TUMOR RESISTANCE;

ANIMALS; ANTINEOPLASTIC AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CARBAZOLES; COLONIC NEOPLASMS; DNA TOPOISOMERASES, TYPE I; DNA, COMPLEMENTARY; DNA, NEOPLASM; DRUG RESISTANCE, MULTIPLE; ENZYME INHIBITORS; FIBROBLASTS; GENE EXPRESSION PROFILING; GLUCOSIDES; HUMANS; INDOLES; LUNG NEOPLASMS; MICE; NEOPLASM PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035300476     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

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