Mouse strains for prostate tumorigenesis based on genes altered in human prostate cancer

Current Drug Targets

Volumn 4, Issue 3, 2003, Pages 263-279

  Powell, W C ^a   Cardiff, R D ^b   Cohen, M B ^c   Miller, G J ^d   Roy Burman, P ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

Animal model; Growth factors; Prostate cancer; Prostate epithelium specific gene inactivation; Retinoid receptors; Tissue specific promoters; Tumor suppressors

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; EFLORNITHINE; ENZYME INHIBITOR; ESTROGEN; FLUOROURACIL; GENISTEIN; KI 67 ANTIGEN; MATRILYSIN; METHYLNITROSOUREA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PRASTERONE; PROSTATE SPECIFIC ANTIGEN; PROTEIN BCL 2; PROTEIN P53; STEROID 5ALPHA REDUCTASE; TESTOSTERONE; TRANSCRIPTION FACTOR; VITAMIN D RECEPTOR;

AGING; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER GROWTH; CARCINOGENESIS; DRUG EFFECT; ENZYME INHIBITION; EXPERIMENTAL MODEL; GENE MUTATION; HISTOPATHOLOGY; HUMAN; KNOCKOUT MOUSE; MOUSE STRAIN; NONHUMAN; ORCHIECTOMY; PHENOTYPE; PROSTATE; PROSTATE CANCER; PROSTATIC INTRAEPITHELIAL NEOPLASIA; REVIEW; TRANSGENIC MOUSE;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PROSTATIC NEOPLASMS; RATS;

EID: 0345268686     PISSN: 13894501     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389450033491145     Document Type: Review

References (159)

1. Rivenson, A. and Silverman, J. (1979) Invest. Urol. 16, 468-472.
2. Huggins, C. (1940) J. Exp. Med. 72, 747-762.
3. Huggins, C. and Hodges, C.V. (1941) Cancer Res. 1, 293-297.
4. Huggins, C., Stevens, R.E.J. and Hodges, C.V. (1941) Arch. Surg. 43, 209-220.
5. Cornell, K.K., Bostwick, D.G., Cooley, D.M., Hall, G., Harvey, H.J., Hendrick, M.J., Pauli, B.U., Render, J.A., Stoica, G., Sweet, D.C. and Waters, D.J. (2000) Prostate 45, 173-183.
6. Weld, K.J., Mayher, B.E., Allay, J.A., Cockroft, J.L., Reed, C.P., Randolph, M.M., Lu, Y., Steiner, M.S. and Gingrich, J.R. (2002) Cancer Gene Ther. 9, 189-196.
7. Pirie-Shepherd, S.R., Coffman, K.T., Resnick, D., Chan, R., Kisker, O., Folkman, J. and Waters, D.J. (2002) Biochem. Biophys. Res. Commun. 292, 886-891.
8. Hazle, J.D., Diederich, C.J., Kangasniemi, M., Price, R.E., Olsson, L.E. and Stafford, R.J. (2002) J. Magn. Reson. Imaging 15, 409-417.
9. Nau, W.H., Diederich, C.J. and Burdette, E.C. (2001) Med. Phys. 28, 1525-1534.
10. Clarke, D.M., Baust, J.M., Van Buskirk, R.G. and Baust, J.G. (2001) Cryobiology 42, 274-285.
11. Cukierski, M.J., Johnson, P.A. and Beck, J.C. (2001) Int. J. Tox. 20, 369-381.
12. Hsi, R.A., Kapatkin, A., Strandberg, J., Zhu, T., Vulcan, T., Solonenko, M., Rodriguez, C., Chang, J., Saunders, M., Mason, N. and Hahn, S. (2001) Clin. Cancer Res. 7, 651-660.
13. Waters, D.J. (1999) Eur. Urol. 35, 456-458.
14. Shirai, T., Takahashi, S., Cui, L., Futakuchi, M., Kato, K., Tamano, S. and Imaida, K. (2000) Mutat. Res. 462, 219-226.
15. Dunning, W. (1963) in National Cancer Institute Monograph 12-Biology of the prostate and related tissues, pp. 351-364.
16. Tennant, T.R., Kim, H., Sokoloff, M. and Rinker-Schaeffer, C.W. (2000) Prostate 43, 295-302.
17. Lubaroff, D.M., Canfield, L. and Reynolds, C.W. (1980) Prog. Clin. Biol. Res. 37, 243-263.
18. Yoshida, B.A., Dubauskas, Z., Chekmareva, M.A., Christiano, T.R., Stadler, W.M. and Rinker-Schaeffer, C.W. (1999) Cancer Res. 59, 5483-5487.
19. Gao, A.C., Lou, W., Dong, J.T. and Isaacs, J.T. (1997) Cancer Res. 57, 846-849.
20. Dong, J.T., Lamb, P.W., Rinker-Schaeffer, C.W., Vukanovic, J., Ichikawa, T., Isaacs, J.T. and Barrett, J.C. (1995) Science 268, 884-886.
21. Newhall, K.R., Isaacs, J.T. and Wright, G.L., Jr. (1990) Prostate 17, 317-325.
22. Bowden, G.T. (1990) Prog. Clin. Biol. Res. 3401), 1-12.
23. Bosland, M.C., Prinsen, M.K. and Kroes, R. (1983) Cancer Lett. 18, 69-78.
24. Bosland, M.C., Prinsen, M.K., Dirksen, T.J. and Spit, B.J. (1990) Cancer Res. 50, 700-709.
25. McCormick, D.L., Rao, K.V., Steele, V.E., Lubet, R.A., Kelloff, G.J. and Bosland, M.C. (1999) Cancer Res. 59, 521-524.
26. Rao, K.V., Johnson, W.D., Bosland, M.C., Lubet, R.A., Steele, V.E., Kelloff, G.J. and McCormick, D.L. (1999) Cancer Res. 59, 3084-3089.
27. Condon, M.S., Kaplan, L.A., Crivello, J.F., Horton, L. and Bosland, M.C. (1999) Mol. Carcinog. 25, 179-186.
28. Gumerlock, P.H., Poonamallee, U.R., Meyers, F.J. and deVere White, R.W. (1991) Cancer Res. 51, 1632-1637.
29. Carter, B.S., Epstein, J.I. and Isaacs, W.B. (1990) Cancer Res. 50, 6830-6832.
30. Peehl, D.M., Wehner, N. and Stamey, T.A. (1987) Prostate 10, 281-289.
31. Noble, R.L. (1977) Cancer Res. 37, 1929-1933.
32. Drago, J.R., Maurer, R.E., Gershwin, M.E., Eckels, D. and Palmer, J.M. (1979) Cancer 44, 424-430.
33. Drago, J.R. and Murray, C. (1984) J. Androl. 5, 265-268.
34. Kadohama, N., Wakisaka, M., Kim, U., Karr, J.P., Murphy, G.P. and Sandberg, A.A. (1985) J. Natl. Cancer Inst. 74, 475-486.
35. Drago, J.R., Worgul, T. and Gershwin, M.E. (1981) J. Surg. Oncol. 16, 353-363.
36. July, L.V., Akbari, M., Zellweger, T., Jones, E.C., Goldenberg, S.L. and Gleave, M.E. (2002) Prostate 50, 179-188.
37. Miyake, H., Nelson, C., Rennie, P.S. and Gleave, M.E. (2000) Cancer Res. 60, 170-176.
38. Ouyang, X.S., Wang, X., Lee, D.T., Tsao, S.W. and Wong, Y.C. (2001) Carcinogenesis 22, 965-973.
39. Xie, W., Wong, Y.C. and Tsao, S.W. (2000) Prostate 44, 31-39.
40. Bostwick, D.G., Ramnani, D. and Qian, J. (2000) Prostate 43, 286-294.
41. Hoehn, W., Schroeder, F.H., Reimann, J.F., Joebsis, A.C. and Hermanek, P. (1980) Prostate 1, 95-104.
42. van Weerden, W.M. and Romijn, J.C. (2000) Prostate 43, 263-271.
43. Cunha, G.R. (1975) Endocrinology 97, 665-673.
44. Cunha, G.R., Sekkingstad, M. and Meloy, B.A. (1983) Differentiation 24, 174-180.
45. Cunha, G.R., Alarid, E.T., Turner, T., Donjacour, A.A., Boutin, E.L. and Foster, B.A. (1992) J. Androl. 13, 465-475.
46. Olumi, A.F., Grossfeld, G.D., Hayward, S.W., Carroll, P.R., Tlsty, T.D. and Cunha, G.R. (1999) Cancer Res. 59, 5002-5011.
47. Wang, Y., Hayward, S.W., Donjacour, A.A., Young, P., Jacks, T., Sage, J., Dahiya, R., Cardiff, R.D., Day, M.L. and Cunha, G.R. (2000) Cancer Res. 60, 6008-6017.
48. Wang, Y., Sudilovsky, D., Zhang, B., Haughney, P.C., Rosen, M.A., Wu, D.S., Cunha, T.J., Dahiya, R., Cunha, G.R. and Hayward, S.W. (2001) Cancer Res. 61, 6064-6072.
49. Lu, X., Park, S.H., Thompson, T.C. and Lane, D.P. (1992) Cell 70, 153-161.
50. Thompson, T.C., Southgate, J., Kitchener, G. and Land, H. (1989) Cell 56, 917-930.
51. McNeal, J.E. (1969) Cancer Metastasis Rev. 23, 24-34.
52. Greene, D.R., Wheeler, T.M., Egawa, S., Dunn, J.K. and Scardino, P.T. (1991) J. Urol. 146, 1069-1076.
53. Bostwick, D.G. (1996) Cancer 78, 330-336.
54. Cunha, G.R., Donjacour, A.A., Cooke, P.S., Mee, S., Bigsby, R.M., Higgins, S.J. and Sugimura, Y. (1987) Endocr. Rev. 8, 338-362.
55. Price, D.K. (1963) in National Cancer Institute Monogram (Vollmer, E.P. and Kauffmann, G., eds), pp. 1-27.
56. Ali, S.H. and DeCaprio, J.A. (2001) Semin. Cancer Biol. 11, 15-23.
57. Kasper, S., Sheppard, P.C., Yan, Y., Pettigrew, N., Borowsky, A.D., Prins, G.S., Dodd, J.G., Duckworth, M.L. and Matusik, R.J. (1998) Lab. Invest. 78, i-xv.
58. Perez-Stable, C., Altman, N.H., Mehta, P.P., Deftos, L.J. and Roos, B.A. (1997) Cancer Res. 57, 900-906.
59. Shibata, M.A., Ward, J.M., Devor, D.E., Liu, M.L. and Green, J.E. (1996) Cancer Res. 56, 4894-4903.
60. Greenberg, N.M., DeMayo, F., Finegold, M.J., Medina, D., Tilley, W.D., Aspinall, J.O., Cunha, G.R., Donjacour, A.A., Matusik, R.J. and Rosen, J.M. (1995) Proc. Natl. Acad. Sci. USA 92, 3439-3443.
61. Gingrich, J.R., Barrios, R.J., Morton, R.A., Boyce, B.F., DeMayo, F.J., Finegold, M.J., Angelopoulou, R., Rosen, J.M. and Greenberg, N.M. (1996) Cancer Res. 56, 4096-4102.
62. Gingrich, J.R., Barrios, R.J., Kattan, M.W., Nahm, H.S., Finegold, M.J. and Greenberg, N.M. (1997) Cancer Res. 57, 4687-4691.
63. Kaplan, P.J., Mohan, S., Cohen, P., Foster, B.A. and Greenberg, N.M. (1999) Cancer Res. 59, 2203-2209.
64. Huss, W.J., Hanrahan, C.F., Barrios, R.J., Simons, J.W. and Greenberg, N.M. (2001) Cancer Res. 61, 2736-2743.
65. Gupta, S., Ahmad, N., Marengo, S.R., MacLennan, G.T., Greenberg, N.M. and Mukhtar, H. (2000) Cancer Res. 60, 5125-5133.
66. Mentor-Marcel, R., Lamartiniere, C.A., Eltoum, I.E., Greenberg, N.M. and Elgavish, A. (2001) Cancer Res. 61, 6777-6782.
67. Gupta, S., Hastak, K., Ahmad, N., Lewin, J.S. and Mukhtar, H. (2001) Proc. Natl. Acad. Sci. USA 98, 10350-10355.
68. Masumori, N., Thomas, T.Z., Chaurand, P., Case, T., Paul, M., Kasper, S., Caprioli, R.M., Tsukamoto, T., Shappell, S.B. and Matusik, R.J. (2001) Cancer Res. 61, 2239-2249.
69. Abate-Shen, C. and Shen, M.M. (2002) Trends Genet. 18, S1-5.
70. Cohen, R.J., Glezerson, G. and Haffejee, Z. (1991) Br. J. Urol. 68, 258-262.
71. Kadmon, D., Thompson, T.C., Lynch, G.R. and Scardino, P.T. (1991) J. Urol. 146, 358-361.
72. Roy-Burman, P., Zheng, J. and Miller, G.J. (1997) Mol. Med. Today 3, 476-482.
73. Latil, A., Bieche, I., Pesche, S., Volant, A., Valeri, A., Fournier, G., Cussenot, O. and Lidereau, R. (1999) Hum. Pathol. 30, 809-815.
74. Ray, F.A., Meyne, J. and Kraemer, P.M. (1992) Mutat. Res. 284. 265-273.
75. Slack, A., Cervoni, N., Pinard, M. and Szyf, M. (1999) J. Biol. Chem. 274, 10105-10112.
76. Toyooka, S., Pass, H.I., Shivapurkar, N., Fukuyama, Y., Maruyama, R., Toyooka, K.O., Gilcrease, M., Farinas, A., Minna, J.D. and Gazdar, A.F. (2001) Cancer Res. 61, 5727-5730.
77. Feuchter, A.E. and Mager, D.L. (1992) Virology 187, 242-250.
78. Frost, J.A., Alberts, A.S., Sontag, E., Guan, K., Mumby, M.C. and Feramisco, J.R. (1994) Mol. Cell. Biol. 14, 6244-6252.
79. Wheat, W.H., Roesler, W.J. and Klemm, D.J. (1994) Mol. Cell. Biol. 14, 5881-5890.
80. Sontag, E., Fedorov, S., Kamibayashi, C., Robbins, D., Cobb, M. and Mumby, M. (1993) Cell 75, 887-897.
81. Maroulakou, I.G., Anver, M., Garrett, L. and Green, J.E. (1994) Proc. Natl. Acad. Sci. USA 91, 11236-11240.
82. Green, J.E., Shibata, M.A., Shibata, E., Moon, R.C., Anver, M.R., Kelloff, G. and Lubet, R. (2001) Cancer Res, 61, 7449-7455.
83. Garabedian, E.M., Humphrey, P.A. and Gordon, J.I. (1998) Proc. Natl. Acad. Sci. USA 95, 15382-15387.
84. Capecchi, M.R. (1994) Sci. Am. 270, 52-59.
85. Copp, A.J. (1995) Trends Genet 11, 87-93.
86. Akagi, K., Sandig, V., Vooijs, M., Van der Valk, M., Giovannini, M., Strauss, M. and Berns, A. (1997) Nucleic Acids Res. 25, 1766-1773.
87. Abdulkadir, S.A., Magee, J.A., Peters, T.J., Kaleem, Z., Naughton, C.K., Humphrey, P.A. and Milbrandt, J. (2002) Mol. Cell. Biol. 22, 1495-1503.
88. Maddison, L.A., Nahm, H., DeMayo, F. and Greenberg, N.M. (2000) Genesis J. Genet. Dev. 26, 154-156.
89. Wu, X., Wu, J., Huang, J., Powell, W.C., Zhang, J., Matusik, R.J., Sangiorgi, F.O., Maxson, R.E., Sucov, H.M. and Roy-Burman, P. (2001) Mech. Dev. 101, 61-69.
90. Zhang, J., Thomas, T.Z., Kasper, S. and Matusik, R.J. (2000) Endocrinology 141, 4698-4710.
91. Soriano, P. (1999) Nat. Genet. 21, 70-71.
92. Qian, J., Hirasawa, K., Bostwick, D.G., Bergstralh, E.J., Slezak, J.M., Anderl, K.L., Borell, T.J., Lieber, M.M. and Jenkins, R.B. (2002) Mod. Pathol. 15, 35-44.
93. Qian, J., Jenkins, R.B. and Bostwick, D.G. (1997) Mod. Pathol. 10, 1113-1119.
94. Fox, S.B., Persad, R.A., Royds, J., Kore, R.N., Silcocks, P.B. and Collins, C.C. (1993) J. Urol. 150, 490-494.
95. Nag, A. and Smith, R.G. (1989) Prostate 15, 115-122.
96. Zhang, X., Lee, C., Ng, P.Y., Rubin, M., Shabsigh, A. and Buttyan, R. (2000) Prostate 43, 278-285.
97. Nelson, K.A. and Witte, J.S. (2002) Am. J. Epidemiol. 155, 883-890.
98. Stanbrough, M., Leav, I., Kwan, P.W., Bubley, G.J. and Balk, S.P. (2001) Proc. Natl. Acad. Sci. USA 98, 10823-10828.
99. Montgomery, J.S., Price, D.K. and Figg, W.D. (2001) J. Pathol. 195, 138-146.
100. Kantoff, P., Giovannucci, E. and Brown, M. (1998) Biochim. Biophys. Acta 1378, C1-5.
101. Merajver, S.D., Frank, T.S., Xu, J., Pham, T.M., Calzone, K.A., Bennett-Baker, P., Chamberlain, J., Boyd, J., Garber, J.E. and Collins, F.S. (1995) Clin. Cancer Res. 1, 539-544.
102. Zhu, X., Dunn, J.M., Goddard, A.D., Squire, J.A., Becker, A., Phillips, R.A. and Gallie, B.L. (1992) Cytogenet. Cell Genet. 59, 248-252.
103. Di Cristofano, A., Pesce, B., Cordon-Cardo, C. and Pandolfi, P.P. (1998) Nat. Genet. 19, 348-355.
104. Kwabi-Addo, B., Giri, D., Schmidt, K., Podsypanina, K., Parsons, R., Greenberg, N. and Ittmann, M. (2001) Proc. Natl. Acad. Sci. USA 98, 11563-11568.
105. Bhatia-Gaur, R., Donjacour, A.A., Sciavolino, P.J., Kim, M., Desai, N., Young, P., Norton, C.R., Gridley, T., Cardiff, R.D., Cunha, G.R., Abate-Shen, C. and Shen, M.M. (1999) Genes Dev. 13, 966-977.
106. He, W.W., Sciavolino, P.J., Wing, J., Augustus, M., Hudson, P., Meissner, P.S., Curtis, R.T., Shell, B.K., Bostwick, D.G., Tindall, D.J., Gelmann, E.P., Abate-Shen, C. and Carter, K.C. (1997) Genomics 43, 69-77.
107. Voeller, H.J., Augustus, M., Madike, V., Bova, G.S., Carter, K.C. and Gelmann, E.P. (1997) Cancer Res. 57, 4455-4459.
108. Schneider, A., Brand, T., Zweigerdt, R. and Arnold, H. (2000) Mech. Dev. 95, 163-174.
109. Tanaka, M., Komuro, I., Inagaki, H., Jenkins, N.A., Copeland, N.G. and Izumo, S. (2000) Dev. Dyn. 219, 248-260.
110. Kim, M.J., Cardiff, R.D., Desai, N., Banach-Petrosky, W.A., Parsons, R., Shen, M.M. and Abate-Shen, C. (2002) Proc. Natl. Acad. Sci. USA 99, 2884-2889.
111. Bowen, C., Bubendorf, L., Voeller, H.J., Slack, R., Willi, N., Sauter, G., Gasser, T.C., Koivisto, P., Lack, E.E., Kononen, J., Kallioniemi, O.P. and Gelmann, E.P. (2000) Cancer Res. 60, 6111-6115.
112. Kim, M.J., Bhatia-Gaur, R., Banach-Petrosky, W.A., Desai, N., Wang, Y., Hayward, S.W., Cunha, G.R., Cardiff, R.D., Shen, M.M. and Abate-Shen, C. (2002) Cancer Res. 62, 2999-3004.
113. Zhong, H., Chiles, K., Feldser, D., Laughner, E., Hanrahan, C., Georgescu, M.M., Simons, J.W. and Semenza, G.L. (2000) Cancer Res. 60, 1541-1545.
114. Di Cristofano, A. and Pandolfi, P.P. (2000) Cell 100, 387-390.
115. Giri, D. and Ittmann, M. (1999) Hum. Pathol. 30, 419-424.
116. Stambolic, V., Suzuki, A., de la Pompa, J.L., Brothers, G.M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J.M., Siderovski, D.P. and Mak, T.W. (1998) Cell 95, 29-39.
117. Vlietstra, R.J., van Alewijk, D.C., Hermans, K.G., van Steenbrugge, G.J. and Trapman, J. (1998) Cancer Res. 58, 2720-2723.
118. Wang, S.I., Parsons, R. and Ittmann, M. (1998) Clin. Cancer Res. 4, 811-815.
119. Whang, Y.E., Wu, X., Suzuki, H., Reiter, R.E., Tran, C., Vessella, R.L., Said, J.W., Isaacs, W.B. and Sawyers, C.L. (1998) Proc. Natl. Acad. Sci. USA 95, 5246-5250.
120. Podsypanina, K., Ellenson, L.H., Nemes, A., Gu, J., Tamura, M., Yamada, K.M., Cordon-Cardo, C., Catoretti, G., Fisher, P.E. and Parsons, R. (1999) Proc. Natl. Acad. Sci. USA 96. 1563-1568.
121. Di Cristofano, A., Kotsi, P., Peng, Y.F., Cordon-Cardo, C., Elkon, K.B. and Pandolfi, P.P. (1999) Science 285, 2122-2125.
122. Leid, M., Kastner, P. and Chambon, P. (1992) Trends Biochem. Sci. 17, 427-433.
123. Chambon, P. (1996) FASEB J. 10, 940-954.
124. Sucov, H.M., Dyson, E., Gumeringer, C.L., Price, J., Chien, K.R. and Evans, R.M. (1994) Genes Dev. 8, 1007-1018.
125. Kastner, P., Grondona, J.M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J.L., Dolle, P. and Chambon, P. (1994) Cell 78, 987-1003.
126. Lohnes, D., Kastner, P., Dierich, A., Mark, M., LeMeur, M. and Chambon, P. (1993) Cell 73, 643-658.
127. Krezel, W., Dupe, V., Mark, M., Dierich, A., Kastner, P. and Chambon, P. (1996) Proc. Natl. Acad. Sci. USA 93, 9010-9014.
128. Mangelsdorf, D.J., Umesono, K. and Evans, R.M. (1994) in The retinoids (Sporn, M.B., Roberts, A.B. and Goodman, D.S. eds), pp. 319-349, Raven Press.
129. Kubota, T., Koshizuka, K., Williamson, E.A., Asou, H., Said, J.W., Holden, S., Miyoshi, I. and Koeffler, H.P. (1998) Cancer Res. 58, 3344-3352.
130. Almasan, A., Mangelsdorf, D.J., Ong, E.S., Wahl, G.M. and Evans, R.M. (1994) Genomics 20, 397-403.
131. Ruijter, E., van de Kaa, C., Miller, G., Ruiter, D., Debruyne, F. and Schalken, J. (1999) Endocr. Rev. 20, 22-45.
132. Faria, T.N., Mendelsohn, C., Chambon, P. and Gudas, L.J. (1999) J. Biol. Chem. 274, 26783-26788.
133. Liu, Y., Lee, M.O., Wang, H.G., Li, Y., Hashimoto, Y., Klaus, M., Reed, J.C. and Zhang, X. (1996) Mol. Cell. Biol. 16, 1138-1149.
134. Lotan, Y., Xu, X.C., Shalev, M., Lotan, R., Williams, R., Wheeler, T.M., Thompson, T.C. and Kadmon, D. (2000) J. Clin. Oncol. 18, 116-121.
135. Sirchia, S.M., Ren, M., Pili, R., Sironi, E., Somenzi, G., Ghidoni, R., Toma, S., Nicolo, G. and Sacchi, N. (2002) Cancer Res. 62, 2455-2461.
136. Kikugawa, T., Tanji, N., Miyazaki, T. and Yokoyama, M. (2000) Anticancer Res. 20, 3897-3902.
137. Matsushima-Nishiwaki, R., Okuno, M., Adachi, S., Sano, T., Akita, K., Moriwaki, H., Friedman, S.L. and Kojima, S. (2001 ) Cancer Res. 61, 7675-7682.
138. Delmotte, M.H., Tahayato, A., Formstecher, P. and Lefebvre, P. (1999) J. Biol. Chem. 274, 38225-38231.
139. Rochette-Egly, C., Adam, S., Rossignol, M., Egly, J.M. and Chambon, P. (1997) Cell 90, 97-107.
140. Huang, J., Powell, W.C., Khodavirdi, A.C., Wu, J., Makita, T., Cardiff, R.D., Cohen, M.B., Sucov, H.M. and Roy-Burman, P. (2002) Cancer Res. 62, 4812-4819.
141. Crossley, P.H. and Martin, G.R. (1995) Development - Supplement 121, 439-451.
142. Rudra-Ganguly, N., Zheng, J., Hoang, A.T. and Roy-Burman, P. (1998) Oncogene 16, 1487-1492.
143. Ghosh, A.K., Shankar, D.B., Shackleford, G.M., Wu, K., T'Ang, A., Miller, G.J., Zheng, J. and Roy-Burman, P. (1996) Cell Growth Differ. 7, 1425-1434.
144. Dorkin, T.J., Robinson, M.C., Marsh, C., Bjartell, A., Neal, D.E. and Leung, H.Y. (1999) Oncogene 18, 2755-2761.
145. Valve, E.M., Nevalainen, M.T., Nurmi, M.J., Laato, M.K., Martikainen, P.M. and Harkonen, P.L. (2001) Lab. Invest. 81, 815-826.
146. Song, Z., Powell, W.C., Kasahara, N., van Bokhoven, A., Miller, G.J. and Roy-Burman, P. (2000) Cancer Res. 60. 6730-6736.
147. Song, Z., Wu, X., Powell, W.C., Tin, R.T., Cardiff, R.D., Cohen, M.B., Matusik, R.J., Miller, G.J. and Roy-Burman, P. (2002) Cancer Res. 62, 5096-5105.
148. Chan, J.M., Stampfer, M.J., Giovannucci, E., Gann, P.H., Ma, J., Wilkinson, P., Hennekens, C.H. and Pollak, M. (1998) Science 279, 563-566.
149. DiGiovanni, J., Kiguchi, K., Frijhoff, A., Wilker, E., Bol, D.K., Beltran, L., Moats, S., Ramirez, A., Jorcano, J. and Conti, C. (2000) Proc. Natl. Acad. Sci. USA 97, 3455-3460.
150. Ruan, W., Powell-Braxton, L., Kopchick, J.J. and Kleinberg, D.L. (1999) Endocrinology 140, 1984-1989.
151. DiGiovanni, J., Bol, D.K., Wilker, E., Beltran, L., Carbajal, S., Moats, S., Ramirez, A., Jorcano, J. and Kiguchi, K. (2000) Cancer Res. 60, 1561-1570.
152. Datta, S.R., Brunet, A. and Greenberg, M.E. (1999) Genes Dev. 13, 2905-2927.
153. Fero, M.L., Rivkin, M., Tasch, M., Porter, P., Carow, C.E., Firpo, E., Polyak, K., Tsai, L.H., Broudy, V., Perlmutter, R.M., Kaushansky, K. and Roberts, J.M. (1996) Cell 85, 733-744.
154. Kiyokawa, H., Kineman, R.D., Manova-Todorova, K.O., Soares, V.C., Hoffman, E.S., Ono, M., Khanam, D., Hayday, A.C., Frohman, L.A. and Koff, A. (1996) Cell 85, 721-732.
155. Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Horii, I. and Loh, D.Y. (1996) Cell 85, 707-720.
156. Macri, E. and Loda, M. (1998) Cancer Metastasis Rev, 17, 337-344.
157. Di Cristofano, A., De Acetis, M., Koff, A., Cordon-Cardo, C. and Pandolfi, P.P. (2001) Nat. Genet. 27, 222-224.
158. Brondani, V., Klimkait, T., Egly, J.M. and Hamy, F. (2002) J. Mol. Biol. 319, 715-728.
159. Park, J.H., Walls, J.E., Galvez, J.J., Kim, M., Abate-Shen, C., Shen, M.M. and Cardiff, R.D. (2002) Am. J. Pathol. 161, 727-735.