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Volumn 95, Issue 1-2, 2000, Pages 163-174

Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: Parallels to glandular duct morphogenesis in prostate

Author keywords

Duct morphogenesis; Epithelial hyperplasia; Gene knock out; Nkx3.1 transcription factor; Prostate and salivary glands

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR;

EID: 0034234783     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(00)00355-5     Document Type: Article
Times cited : (97)

References (52)
  • 1
    • 0027237596 scopus 로고
    • Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • Azpiazu N., Frasch M. tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 7:1993;1325-1340.
    • (1993) Genes Dev. , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 4
    • 0031959594 scopus 로고    scopus 로고
    • Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart
    • Biben C., Hatzistavrou T., Harvey R.P. Expression of NK-2 class homeobox gene Nkx2-6 in foregut endoderm and heart. Mech. Dev. 73:1998;125-127.
    • (1998) Mech. Dev. , vol.73 , pp. 125-127
    • Biben, C.1    Hatzistavrou, T.2    Harvey, R.P.3
  • 5
    • 0029768633 scopus 로고    scopus 로고
    • Prostate-specific and androgen-dependent expression of a novel homeobox gene
    • Bieberich C.J., Fujita K., He W.W., Jay G. Prostate-specific and androgen-dependent expression of a novel homeobox gene. J. Biol. Chem. 271:1996;31779-31782.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31779-31782
    • Bieberich, C.J.1    Fujita, K.2    He, W.W.3    Jay, G.4
  • 7
    • 0030746215 scopus 로고    scopus 로고
    • Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development
    • Brand T., Andree B., Schneider A., Buchberger A., Arnold H.H. Chicken NKx2-8, a novel homeobox gene expressed during early heart and foregut development. Mech. Dev. 64:1997;53-59.
    • (1997) Mech. Dev. , vol.64 , pp. 53-59
    • Brand, T.1    Andree, B.2    Schneider, A.3    Buchberger, A.4    Arnold, H.H.5
  • 8
    • 0026437438 scopus 로고
    • Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death
    • Braun T., Rudnicki M.A., Arnold H.H., Jaenisch R. Targeted inactivation of the muscle regulatory gene Myf-5 results in abnormal rib development and perinatal death. Cell. 71:1992;369-382.
    • (1992) Cell , vol.71 , pp. 369-382
    • Braun, T.1    Rudnicki, M.A.2    Arnold, H.H.3    Jaenisch, R.4
  • 10
    • 0029984771 scopus 로고    scopus 로고
    • Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: Differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development
    • Buchberger A., Pabst O., Brand T., Seidl K., Arnold H.H. Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeobox gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development. Mech. Dev. 56:1996;151-163.
    • (1996) Mech. Dev. , vol.56 , pp. 151-163
    • Buchberger, A.1    Pabst, O.2    Brand, T.3    Seidl, K.4    Arnold, H.H.5
  • 11
    • 0028122476 scopus 로고
    • The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively
    • Copeland N.G., Jenkins N.A., Harvey R.P. The murine homeobox genes Nkx2.3 and Nkx2.6 are located on chromosomes 19 and 14, respectively. Genomics. 22:1994;655-656.
    • (1994) Genomics , vol.22 , pp. 655-656
    • Copeland, N.G.1    Jenkins, N.A.2    Harvey, R.P.3
  • 12
    • 0028095580 scopus 로고
    • Mechanisms of mRNA degradation in eukaryotes
    • Decker C.J., Parker R. Mechanisms of mRNA degradation in eukaryotes. Trends Biochem. Sci. 19:1994;336-340.
    • (1994) Trends Biochem. Sci. , vol.19 , pp. 336-340
    • Decker, C.J.1    Parker, R.2
  • 13
    • 0029005521 scopus 로고
    • Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts
    • Decker C.J., Parker R. Diversity of cytoplasmic functions for the 3′ untranslated region of eukaryotic transcripts. Curr. Opin. Cell Biol. 7:1995;386-392.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 386-392
    • Decker, C.J.1    Parker, R.2
  • 14
    • 0028863326 scopus 로고
    • Tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman
    • Evans S.M., Yan W., Murillo M.P., Ponce J., Papalopulu N. tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman. Development. 121:1995;3889-3899.
    • (1995) Development , vol.121 , pp. 3889-3899
    • Evans, S.M.1    Yan, W.2    Murillo, M.P.3    Ponce, J.4    Papalopulu, N.5
  • 15
    • 0028630689 scopus 로고
    • Patterning of mammalian somites by surface ectoderm and notochord: Evidence for sclerotome induction by a hedgehog homolog
    • Fan C.M., Tessier-Lavigne M. Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog. Cell. 79:1994;1175-1186.
    • (1994) Cell , vol.79 , pp. 1175-1186
    • Fan, C.M.1    Tessier-Lavigne, M.2
  • 16
    • 0031647381 scopus 로고    scopus 로고
    • Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner
    • Fu Y., Yan W., Mohun T.J., Evans S.M. Vertebrate tinman homologues XNkx2-3 and XNkx2-5 are required for heart formation in a functionally redundant manner. Development. 125:1998;4439-4449.
    • (1998) Development , vol.125 , pp. 4439-4449
    • Fu, Y.1    Yan, W.2    Mohun, T.J.3    Evans, S.M.4
  • 17
    • 0001093537 scopus 로고
    • Gene and enhancer trap screens in ES cell chimeras
    • Oxford: IRL Press
    • Gossler A., Zachgo J. Gene and enhancer trap screens in ES cell chimeras. Gene Targeting. A Practical Approach. 1993;181-225 IRL Press, Oxford.
    • (1993) Gene Targeting. a Practical Approach , pp. 181-225
    • Gossler, A.1    Zachgo, J.2
  • 18
    • 0032380010 scopus 로고    scopus 로고
    • Tinman function is essential for vertebrate heart development: Elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5
    • Grow M.W., Krieg P.A. Tinman function is essential for vertebrate heart development: elimination of cardiac differentiation by dominant inhibitory mutants of the tinman-related genes, XNkx2-3 and XNkx2-5. Dev. Biol. 204:1998;187-196.
    • (1998) Dev. Biol. , vol.204 , pp. 187-196
    • Grow, M.W.1    Krieg, P.A.2
  • 19
    • 0033136589 scopus 로고    scopus 로고
    • Morphological features of the minor salivary glands
    • Hand A.R., Pathmanathan D., Field R.B. Morphological features of the minor salivary glands. Arch. Oral Biol. 44:(Suppl. 1):1999;S3-S10.
    • (1999) Arch. Oral Biol. , vol.44 , Issue.SUPPL. 1 , pp. 3-S10
    • Hand, A.R.1    Pathmanathan, D.2    Field, R.B.3
  • 20
    • 0030587603 scopus 로고    scopus 로고
    • NK-2 homeobox genes and heart development
    • Harvey R.P. NK-2 homeobox genes and heart development. Dev. Biol. 178:1996;203-216.
    • (1996) Dev. Biol. , vol.178 , pp. 203-216
    • Harvey, R.P.1
  • 23
    • 0028651869 scopus 로고
    • Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites
    • Johnson R.L., Laufer E., Riddle R.D., Tabin C. Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites. Cell. 79:1994;1165-1173.
    • (1994) Cell , vol.79 , pp. 1165-1173
    • Johnson, R.L.1    Laufer, E.2    Riddle, R.D.3    Tabin, C.4
  • 24
    • 0030057596 scopus 로고    scopus 로고
    • The T/ebp null mouse: Thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary
    • Kimura S., Hara Y., Pineau T., Fernandez-Salguero P., Fox C.H., Ward J.M., Gonzalez F.J. The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. Genes Dev. 10:1996;60-69.
    • (1996) Genes Dev. , vol.10 , pp. 60-69
    • Kimura, S.1    Hara, Y.2    Pineau, T.3    Fernandez-Salguero, P.4    Fox, C.H.5    Ward, J.M.6    Gonzalez, F.J.7
  • 25
    • 0027184211 scopus 로고
    • Csx: A murine homeobox-containing gene specifically expressed in the developing heart
    • Komuro I., Izumo S. Csx: a murine homeobox-containing gene specifically expressed in the developing heart. Proc. Natl. Acad. Sci. USA. 90:1993;8145-8149.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8145-8149
    • Komuro, I.1    Izumo, S.2
  • 26
    • 0031930644 scopus 로고    scopus 로고
    • Mediolateral patterning of somites: Multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression
    • Kos L., Chiang C., Mahon K.A. Mediolateral patterning of somites: multiple axial signals, including Sonic hedgehog, regulate Nkx-3.1 expression. Mech. Dev. 70:1998;25-34.
    • (1998) Mech. Dev. , vol.70 , pp. 25-34
    • Kos, L.1    Chiang, C.2    Mahon, K.A.3
  • 27
    • 0026340586 scopus 로고
    • The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain
    • Lazzaro D., Price M., de Felice M., Di Lauro R. The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development. 113:1991;1093-1104.
    • (1991) Development , vol.113 , pp. 1093-1104
    • Lazzaro, D.1    Price, M.2    De Felice, M.3    Di Lauro, R.4
  • 29
    • 0027700251 scopus 로고
    • Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
    • Lints T.J., Parsons L.M., Hartley L., Lyons I., Harvey R.P. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development. 119:1993;969.
    • (1993) Development , vol.119 , pp. 969
    • Lints, T.J.1    Parsons, L.M.2    Hartley, L.3    Lyons, I.4    Harvey, R.P.5
  • 30
    • 0029090829 scopus 로고
    • Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5
    • Lyons I., Parsons L.M., Hartley L., Li R., Andrews J.E., Robb L., Harvey R.P. Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev. 9:1995;1654-1666.
    • (1995) Genes Dev. , vol.9 , pp. 1654-1666
    • Lyons, I.1    Parsons, L.M.2    Hartley, L.3    Li, R.4    Andrews, J.E.5    Robb, L.6    Harvey, R.P.7
  • 31
    • 0002077379 scopus 로고    scopus 로고
    • Formation and septation of the tubular heart. Integrating the dynamics of morphology with emerging molecular concepts
    • Boston, MA: Birkhäuser
    • Markwald R.R., Trush T., Moreno-Rodriguez R. Formation and septation of the tubular heart. Integrating the dynamics of morphology with emerging molecular concepts. Living Morphogenesis of the Heart. 1999;43-84 Birkhäuser, Boston, MA.
    • (1999) Living Morphogenesis of the Heart , pp. 43-84
    • Markwald, R.R.1    Trush, T.2    Moreno-Rodriguez, R.3
  • 32
    • 0031835362 scopus 로고    scopus 로고
    • Tinman-related genes expressed during heart development in Xenopus
    • Newman C.S., Krieg P.A. tinman-related genes expressed during heart development in Xenopus. Dev. Genet. 22:1998;230-238.
    • (1998) Dev. Genet. , vol.22 , pp. 230-238
    • Newman, C.S.1    Krieg, P.A.2
  • 33
    • 0030899175 scopus 로고    scopus 로고
    • The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- And postnatal mouse development
    • Pabst O., Schneider A., Brand T., Arnold H.H. The mouse Nkx2-3 homeodomain gene is expressed in gut mesenchyme during pre- and postnatal mouse development. Dev. Dyn. 209:1997;29-35.
    • (1997) Dev. Dyn. , vol.209 , pp. 29-35
    • Pabst, O.1    Schneider, A.2    Brand, T.3    Arnold, H.H.4
  • 34
    • 0032974961 scopus 로고    scopus 로고
    • Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen
    • Pabst O., Zweigerdt R., Arnold H.H. Targeted disruption of the homeobox transcription factor Nkx2-3 in mice results in postnatal lethality and abnormal development of small intestine and spleen. Development. 126:1999;2215-2225.
    • (1999) Development , vol.126 , pp. 2215-2225
    • Pabst, O.1    Zweigerdt, R.2    Arnold, H.H.3
  • 35
    • 0033966374 scopus 로고    scopus 로고
    • NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos
    • Pabst O., Herbrand H., Takuma N., Arnold H.H. NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos. Dev. Genes Evol. 210:2000;47-50.
    • (2000) Dev. Genes Evol. , vol.210 , pp. 47-50
    • Pabst, O.1    Herbrand, H.2    Takuma, N.3    Arnold, H.H.4
  • 36
    • 0032563948 scopus 로고    scopus 로고
    • Sonic hedgehog regulates branching morphogenesis in the mammalian lung
    • Pepicelli C.V., Lewis P.M., McMahon A.P. Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr. Biol. 8:1998;1083-1086.
    • (1998) Curr. Biol. , vol.8 , pp. 1083-1086
    • Pepicelli, C.V.1    Lewis, P.M.2    McMahon, A.P.3
  • 37
    • 0033136040 scopus 로고    scopus 로고
    • Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium
    • Podlasek C.A., Barnett D.H., Clemens J.Q., Bak P.M., Bushman W. Prostate development requires Sonic hedgehog expressed by the urogenital sinus epithelium. Dev. Biol. 209:1999;28-39.
    • (1999) Dev. Biol. , vol.209 , pp. 28-39
    • Podlasek, C.A.1    Barnett, D.H.2    Clemens, J.Q.3    Bak, P.M.4    Bushman, W.5
  • 38
    • 0031571635 scopus 로고    scopus 로고
    • Chicken Nkx-2.8: A novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm
    • Reecy J.M., Yamada M., Cummings K., Sosic D., Chen C.Y., Eichele G., Olson E.N., Schwartz R.J. Chicken Nkx-2.8: a novel homeobox gene expressed in early heart progenitor cells and pharyngeal pouch-2 and -3 endoderm. Dev. Biol. 188:1997;295-311.
    • (1997) Dev. Biol. , vol.188 , pp. 295-311
    • Reecy, J.M.1    Yamada, M.2    Cummings, K.3    Sosic, D.4    Chen, C.Y.5    Eichele, G.6    Olson, E.N.7    Schwartz, R.J.8
  • 39
    • 33645518276 scopus 로고    scopus 로고
    • The homeobox gene NKX3.2 is a target of left-right signalling and is expressed on opposite sides in chick and mouse embryos
    • Schneider A., Mijalski T., Schlange T., Dai W., Overbeek P., Arnold H.H., Brand T. The homeobox gene NKX3.2 is a target of left-right signalling and is expressed on opposite sides in chick and mouse embryos. Curr. Biol. 9:1999;911-914.
    • (1999) Curr. Biol. , vol.9 , pp. 911-914
    • Schneider, A.1    Mijalski, T.2    Schlange, T.3    Dai, W.4    Overbeek, P.5    Arnold, H.H.6    Brand, T.7
  • 41
    • 0031843386 scopus 로고    scopus 로고
    • Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells
    • Sussel L., Kalamaras J., Hartigan-O'Connor D.J., Meneses J.J., Pedersen R.A., Rubenstein J.L., German M.S. Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells. Development. 125:1998;2213-2221.
    • (1998) Development , vol.125 , pp. 2213-2221
    • Sussel, L.1    Kalamaras, J.2    Hartigan-O'Connor, D.J.3    Meneses, J.J.4    Pedersen, R.A.5    Rubenstein, J.L.6    German, M.S.7
  • 42
    • 0032841612 scopus 로고    scopus 로고
    • Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: Evidence for a transformation of the pallidum into the striatum
    • Sussel L., Marin O., Kimura S., Rubenstein J.L. Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum. Development. 126:1999;3359-3370.
    • (1999) Development , vol.126 , pp. 3359-3370
    • Sussel, L.1    Marin, O.2    Kimura, S.3    Rubenstein, J.L.4
  • 44
    • 0032907924 scopus 로고    scopus 로고
    • The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development
    • Tanaka M., Chen Z., Bartunkova S., Yamasaki N., Izumo S. The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 126:1999;1269-1280.
    • (1999) Development , vol.126 , pp. 1269-1280
    • Tanaka, M.1    Chen, Z.2    Bartunkova, S.3    Yamasaki, N.4    Izumo, S.5
  • 45
    • 0033167326 scopus 로고    scopus 로고
    • Expression of the Nkx3.1 homobox gene during pre and postnatal development
    • Tanaka M., Lyons G.E., Izumo S. Expression of the Nkx3.1 homobox gene during pre and postnatal development. Mech. Dev. 85:1999;179-182.
    • (1999) Mech. Dev. , vol.85 , pp. 179-182
    • Tanaka, M.1    Lyons, G.E.2    Izumo, S.3
  • 47
    • 0030730924 scopus 로고    scopus 로고
    • Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe
    • Tribioli C., Lufkin T. Molecular cloning, chromosomal mapping and developmental expression of BAPX1, a novel human homeobox-containing gene homologous to Drosophila bagpipe. Gene. 203:1997;225-233.
    • (1997) Gene , vol.203 , pp. 225-233
    • Tribioli, C.1    Lufkin, T.2
  • 48
    • 0033379122 scopus 로고    scopus 로고
    • The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen
    • Tribioli C., Lufkin T. The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen. Development. 126:1999;5699-5711.
    • (1999) Development , vol.126 , pp. 5699-5711
    • Tribioli, C.1    Lufkin, T.2
  • 49
    • 0031193948 scopus 로고    scopus 로고
    • Bapx1: An evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton
    • Tribioli C., Frasch M., Lufkin T. Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. Mech. Dev. 65:1997;145-162.
    • (1997) Mech. Dev. , vol.65 , pp. 145-162
    • Tribioli, C.1    Frasch, M.2    Lufkin, T.3
  • 50
    • 0025780879 scopus 로고
    • Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
    • Tybulewicz V.L., Crawford C.E., Jackson P.K., Bronson R.T., Mulligan R.C. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell. 65:1991;1153-1163.
    • (1991) Cell , vol.65 , pp. 1153-1163
    • Tybulewicz, V.L.1    Crawford, C.E.2    Jackson, P.K.3    Bronson, R.T.4    Mulligan, R.C.5
  • 52
    • 0030822020 scopus 로고    scopus 로고
    • Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers (published erratum appears in Cancer Res. 1997, 57(24), 5613)
    • Voeller H.J., Augustus M., Madike V., Bova G.S., Carter K.C., Gelmann E.P. Coding region of NKX3.1, a prostate-specific homeobox gene on 8p21, is not mutated in human prostate cancers (published erratum appears in Cancer Res. 1997, 57(24), 5613). Cancer Res. 57:1997;4455-4459.
    • (1997) Cancer Res. , vol.57 , pp. 4455-4459
    • Voeller, H.J.1    Augustus, M.2    Madike, V.3    Bova, G.S.4    Carter, K.C.5    Gelmann, E.P.6


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