메뉴 건너뛰기




Volumn 158, Issue 9, 1997, Pages 4137-4144

An Ovalbumin-IL-12 Fusion Protein Is More Effective than Ovalbumin Plus Free Recombinant IL-12 in Inducing a T Helper Cell Type 1-Dominated Immune Response and Inhibiting Antigen-Specific IgE Production

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAMMA INTERFERON; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN 12; OVALBUMIN;

EID: 0031134912     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (166)

References (34)
  • 1
    • 0028518985 scopus 로고
    • Generation and in vivo persistence of polarized Th1 and Th2 memory cells
    • Swain, S. L. 1994. Generation and in vivo persistence of polarized Th1 and Th2 memory cells. Immunity 1:543.
    • (1994) Immunity , vol.1 , pp. 543
    • Swain, S.L.1
  • 2
    • 0028265155 scopus 로고
    • Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones
    • Manetti, R., F. Gerosa, M. G. Giudizi, R. Biagiotti, P. Parronchi, M. P. Piccinni, S. Sampognaro, E. Maggi, S. Romagnani, G. Trinchieri. 1994. Interleukin 12 induces stable priming for interferon gamma (IFN-gamma) production during differentiation of human T helper (Th) cells and transient IFN-gamma production in established Th2 cell clones.J Exp. Med. 179:1273.
    • (1994) J Exp. Med. , vol.179 , pp. 1273
    • Manetti, R.1    Gerosa, F.2    Giudizi, M.G.3    Biagiotti, R.4    Parronchi, P.5    Piccinni, M.P.6    Sampognaro, S.7    Maggi, E.8    Romagnani, S.9    Trinchieri, G.10
  • 3
  • 4
    • 0028821825 scopus 로고
    • Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
    • Gavett, S. H., D. J. O'Hearn, X. Li, S. K. Huang, F. D. Finkelman, and M. Wills-Karp. 1995. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J. Exp. Med. 182:1527.
    • (1995) J. Exp. Med. , vol.182 , pp. 1527
    • Gavett, S.H.1    O'Hearn, D.J.2    Li, X.3    Huang, S.K.4    Finkelman, F.D.5    Wills-Karp, M.6
  • 5
    • 0029042649 scopus 로고
    • IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia
    • Wynn, T. A., D. Jankovic, S. Hieny, A. W. Cheever, and A. Sher. 1995. IL-12 enhances vaccine-induced immunity to Schistosoma mansoni in mice and decreases T helper 2 cytokine expression, IgE production, and tissue eosinophilia. J. Immunol. 154:4701.
    • (1995) J. Immunol. , vol.154 , pp. 4701
    • Wynn, T.A.1    Jankovic, D.2    Hieny, S.3    Cheever, A.W.4    Sher, A.5
  • 7
    • 0029973242 scopus 로고    scopus 로고
    • Immunoregulation by interleukin-12
    • Trinchieri, G., and F. Gerosa. 1996. Immunoregulation by interleukin-12. J. Leukocyte Biol. 59:505.
    • (1996) J. Leukocyte Biol. , vol.59 , pp. 505
    • Trinchieri, G.1    Gerosa, F.2
  • 12
    • 0030002449 scopus 로고    scopus 로고
    • 1L-12 synergizes with IL-2 and other stimuli in inducing IL-10 production by human T cells
    • Jeannin, P., Y. Delneste, M. Seveso, P. Life, and J. Y. Bonnefoy. 1996. 1L-12 synergizes with IL-2 and other stimuli in inducing IL-10 production by human T cells. J. Immunol. 156:3159.
    • (1996) J. Immunol. , vol.156 , pp. 3159
    • Jeannin, P.1    Delneste, Y.2    Seveso, M.3    Life, P.4    Bonnefoy, J.Y.5
  • 13
  • 14
    • 0019364279 scopus 로고
    • Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression
    • Ozato, K., and D. H. Sachs. 1981. Monoclonal antibodies to mouse MHC antigens. III. Hybridoma antibodies reacting to antigens of the H-2b haplotype reveal genetic control of isotype expression. J. Immunol. 126:317.
    • (1981) J. Immunol. , vol.126 , pp. 317
    • Ozato, K.1    Sachs, D.H.2
  • 15
    • 0023821578 scopus 로고
    • Introduction of soluble protein into the class I pathway of antigen processing and presentation
    • Moore, M. W., F. R. Carbone, and J. J. Bevan. 1988. Introduction of soluble protein into the class I pathway of antigen processing and presentation. Cell 54:777.
    • (1988) Cell , vol.54 , pp. 777
    • Moore, M.W.1    Carbone, F.R.2    Bevan, J.J.3
  • 17
    • 0026431613 scopus 로고
    • Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus
    • Kaufman, R. J., M. V. Davies, L. C. Wasley, and D. Michnick. 1991. Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus. Nucleic Acids Res. 19:4485.
    • (1991) Nucleic Acids Res. , vol.19 , pp. 4485
    • Kaufman, R.J.1    Davies, M.V.2    Wasley, L.C.3    Michnick, D.4
  • 18
    • 0027216863 scopus 로고
    • Anti-TAPA-1 antibodies induce protein tyrosine phosphorylation that is prevented by increasing intracellular thiol levels
    • Schick, M. R., N. Q. Ngujen, and S. Levy. 1993. Anti-TAPA-1 antibodies induce protein tyrosine phosphorylation that is prevented by increasing intracellular thiol levels. J. Immunol 151:1918.
    • (1993) J. Immunol , vol.151 , pp. 1918
    • Schick, M.R.1    Ngujen, N.Q.2    Levy, S.3
  • 19
    • 0027598183 scopus 로고
    • Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins
    • Gillies, S. D., D. Young, K. M. Lo, and S. Roberts. 1993. Biological activity and in vivo clearance of antitumor antibody/cytokine fusion proteins. Bioconj. Chem. 4:230.
    • (1993) Bioconj. Chem. , vol.4 , pp. 230
    • Gillies, S.D.1    Young, D.2    Lo, K.M.3    Roberts, S.4
  • 20
    • 0027996540 scopus 로고
    • Idiotype-cytokine fusion proteins as cancer vaccines: Relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor
    • Chen, T. T., M. H. Tao, and R. Levy. 1994. Idiotype-cytokine fusion proteins as cancer vaccines: relative efficacy of IL-2, IL-4, and granulocyte-macrophage colony-stimulating factor. J. Immunol. 153:4775.
    • (1994) J. Immunol. , vol.153 , pp. 4775
    • Chen, T.T.1    Tao, M.H.2    Levy, R.3
  • 21
    • 0024328379 scopus 로고
    • Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: The role of endogenous interleukin 1 in proliferative responses
    • Grun, J. L., and P. H. Maurer. 1989. Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses. Cell. Immunol. 121:134.
    • (1989) Cell. Immunol. , vol.121 , pp. 134
    • Grun, J.L.1    Maurer, P.H.2
  • 22
    • 0027534132 scopus 로고
    • Allergen-dependent induction of interleukin-4 synthesis in vivo
    • Yang, X., and K. T. Hayglass. 1993. Allergen-dependent induction of interleukin-4 synthesis in vivo. Immunology 78:74.
    • (1993) Immunology , vol.78 , pp. 74
    • Yang, X.1    Hayglass, K.T.2
  • 24
    • 0028901793 scopus 로고
    • Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated Y cell cultures
    • Jutel, M., W. J. Pichler, D. Skrbic, A. Urwyler, C. Dahinden, and U. R. Muller. 1995. Bee venom immunotherapy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated Y cell cultures. J. Immunol. 154:4187.
    • (1995) J. Immunol. , vol.154 , pp. 4187
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Muller, U.R.6
  • 25
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • Varney, V. A., Q. A. Hamid, M. Gaga, S. Ying, M. Jacobson, A. J. Frew, A. B. Kay, and S. R. Durham. 1993. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J. Clin. Invest. 92:644.
    • (1993) J. Clin. Invest. , vol.92 , pp. 644
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3    Ying, S.4    Jacobson, M.5    Frew, A.J.6    Kay, A.B.7    Durham, S.R.8
  • 26
    • 0028970060 scopus 로고
    • Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adoptive immunity
    • Trinchieri, G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adoptive immunity. Annu. Rev. Immunol. 13:251.
    • (1995) Annu. Rev. Immunol. , vol.13 , pp. 251
    • Trinchieri, G.1
  • 27
    • 0028877056 scopus 로고
    • Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations
    • Openshaw, P., E. E. Murphy, N. A. Hosken, V. Maino, K. Davis, K. Murphy, and A. O'Garra. 1995. Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populations. J. Exp. Med. 182: 1357.
    • (1995) J. Exp. Med. , vol.182 , pp. 1357
    • Openshaw, P.1    Murphy, E.E.2    Hosken, N.A.3    Maino, V.4    Davis, K.5    Murphy, K.6    O'Garra, A.7
  • 28
    • 0028934155 scopus 로고
    • Switch from a type 2 to a type 1 T helper cell response and cure of established Laeishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam
    • Nabors, G. S., L. C. Afonso, J. P. Farrell, and P. Scott. 1995. Switch from a type 2 to a type 1 T helper cell response and cure of established Laeishmania major infection in mice is induced by combined therapy with interleukin 12 and Pentostam. Proc. Natl. Acad. Sci. USA 92:3142.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3142
    • Nabors, G.S.1    Afonso, L.C.2    Farrell, J.P.3    Scott, P.4
  • 31
    • 0029919272 scopus 로고    scopus 로고
    • Immunotherapy of cancer with genetically modified tumor vaccines
    • Gilboa, E. 1996. Immunotherapy of cancer with genetically modified tumor vaccines. Semin. Oncol. 23:101.
    • (1996) Semin. Oncol. , vol.23 , pp. 101
    • Gilboa, E.1
  • 32
    • 0029925502 scopus 로고    scopus 로고
    • Immunoprophylaxis of allergen-induced immunoglobulin e synthesis and airway hyperresponsiveness in vivo by genetic immunization
    • Hsu, C. H., K. Y. Chua, M. H. Tao, Y. L. Lai, H. D. Wu, S. K. Huang, and K. H. Hsieh. 1996. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nat. Med. 2:540.
    • (1996) Nat. Med. , vol.2 , pp. 540
    • Hsu, C.H.1    Chua, K.Y.2    Tao, M.H.3    Lai, Y.L.4    Wu, H.D.5    Huang, S.K.6    Hsieh, K.H.7
  • 34
    • 0026708718 scopus 로고
    • Regulation of immunity to parasites by T cells and T cell-derived cytokines
    • Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385.
    • (1992) Annu. Rev. Immunol. , vol.10 , pp. 385
    • Sher, A.1    Coffman, R.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.