Immunological tolerance to inhaled antigen

American Journal of Respiratory and Critical Care Medicine

Volumn 162, Issue 4 II, 2000, Pages

  Hoyne, Gerard F ^a   Tan, Karen ^a   Corsin Jimenez, Marta ^a   Wahl, Karen ^a   Stewart, Mairi ^a   Howie, Sarah E M ^a   Lamb, Jonathan R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN;

ALLERGIC DISEASE; CONFERENCE PAPER; HELPER CELL; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RESPIRATORY SYSTEM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION;

EID: 0033763860     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.162.supplement_3.15tac6     Document Type: Conference Paper

References (50)

1. Down-regulation of immune responses to inhaled antigen: Studies on the mechanism of induced suppression
2. Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation
3. + T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production
4. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse
5. Murine animal models to study the central role of T cells in immediate-type hypersensitivity responses
6. Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy
7. + or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization
8. + T cells
9. Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type 1 allergy
10. Murine allergic respiratory responses to the major house dust mite allergen Der p 1
11. Studies on the density, distribution, and surface phenotype of intraepithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways
12. Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: Differential regulation of Ia expression at different levels of the respiratory tract
13. Regulation of T-cell sensitization at epithelial surfaces in the respiratory tract: Suppression of IgE responses to inhaled antigens by CD3+ TCR alpha-/beta-lymphocytes (putative gamma/delta T cells)
14. Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells
15. Inhibition of IgE production and normalization of airways responsiveness by sensitized CD8 T cells in a mouse model of allergen-induced sensitization
16. TH2-polarized immunological memory to inhalant allergens in atopics is established during infancy and early childhood
17. Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes
18. Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells
19. Requirement for gammadelta T cells in allergic airway inflammation
20. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
21. Characterization of the specificity and duration of T cell tolerance to intranasally administered peptides in mice: A role for intramolecular epitope suppression
22. + T cells precedes the development of tolerance in vivo
23. Peptide-induced T cell regulation of experimental autoimmune encephalomyelitis: A role for IL-10
24. Hierarchy in the ability of T cell epitopes to induce peripheral tolerance to antigens from myelin
25. Inhibition of experimental autoimmune encephalomyelitis by inhalation but not oral administration of the encephalitogenic peptide: Influence of MHC binding affinity
26. Mucosal tolerance and suppression of collagen-induced arthritis (CIA) induced by nasal inhalation of synthetic peptide 184-198 of bovine type II collagen (CII) expressing a dominant T cell epitope
27. Intranasal administration of retinal antigens suppresses retinal antigen-induced experimental autoimmune uveoretinitis
28. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
29. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering
30. Regulatory T cells and inflammatory bowel disease
31. Control of immune pathology by regulatory T cells
32. Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
33. Induction of circulating myelin basic protein and proteolipid protein-specific transforming growth factor-betal-secreting Th3 T cells by oral administration of myelin in multiple sclerosis patients
34. + T cells: A population of T cells with immune regulatory activities in vitro
35. + T cells
36. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
37. + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
38. Regulation of T cell function in mucosal tolerance
39. Notch signaling: Cell fate control and signal integration in development
40. Notch signaling
41. LIN-12/Notch signaling: Lessons from worms and flies
42. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
43. Notch and the immune system
44. Regulation of T cell fate by Notch
45. Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation
46. The role of Notch in lateral inhibition and cell fate specification
47. Linked suppression in peripheral T cell tolerance to the house dust mite derived allergen Der p 1
48. Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells
49. Protective effects of notch-1 on TCR-induced apoptosis
50. An ancient system of host defense