-
1
-
-
0022380768
-
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice
-
Adams J.M., Harris A.W., Pinkert C.A., Corcoran L.M., Alexander W.S., Cory S., Palmiter R.D., Brinster R.L. The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice. Nature. 318:1985;533-538.
-
(1985)
Nature
, vol.318
, pp. 533-538
-
-
Adams, J.M.1
Harris, A.W.2
Pinkert, C.A.3
Corcoran, L.M.4
Alexander, W.S.5
Cory, S.6
Palmiter, R.D.7
Brinster, R.L.8
-
2
-
-
0034014308
-
Complex transcriptional regulatory mechanisms control expression of the E2F3 locus
-
Adams M.R., Sears R., Nuckolls F., Leone G., Nevins J.R. Complex transcriptional regulatory mechanisms control expression of the E2F3 locus. Mol. Cell. Biol. 20:2000;3633-3639.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3633-3639
-
-
Adams, M.R.1
Sears, R.2
Nuckolls, F.3
Leone, G.4
Nevins, J.R.5
-
3
-
-
0025937489
-
Constitutive c-myc expression in an IL3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
-
Askew D.S., Ashmun R.A., Simmons B.C., Cleveland J.L. Constitutive c-myc expression in an IL3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene. 6:1991;1915-1922.
-
(1991)
Oncogene
, vol.6
, pp. 1915-1922
-
-
Askew, D.S.1
Ashmun, R.A.2
Simmons, B.C.3
Cleveland, J.L.4
-
4
-
-
0035067387
-
P27 destruction: Cks1 pulls the trigger
-
Bartek J., Lukas J. p27 destruction. Cks1 pulls the trigger Nat. Cell Biol. 3:2001;E95-E98.
-
(2001)
Nat. Cell Biol.
, vol.3
-
-
Bartek, J.1
Lukas, J.2
-
6
-
-
0024420150
-
Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures
-
Borzillo G.V., Sherr C.J. Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures. Mol. Cell. Biol. 9:1989;3973-3981.
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 3973-3981
-
-
Borzillo, G.V.1
Sherr, C.J.2
-
7
-
-
0033214080
-
Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27
-
Bouchard C., Thieke K., Maier A., Saffrich R., Hanley-Hyde J., Ansorge W., Reed S., Sicinski P., Bartek J., Eilers M. Direct induction of cyclin D2 by Myc contributes to cell cycle progression and sequestration of p27. EMBO J. 18:1999;5321-5333.
-
(1999)
EMBO J.
, vol.18
, pp. 5321-5333
-
-
Bouchard, C.1
Thieke, K.2
Maier, A.3
Saffrich, R.4
Hanley-Hyde, J.5
Ansorge, W.6
Reed, S.7
Sicinski, P.8
Bartek, J.9
Eilers, M.10
-
8
-
-
0030738479
-
Distinct roles for E2F proteins in cell growth control and apoptosis
-
DeGregori J., Leone G., Miron A., Jakoi L., Nevins J. Distinct roles for E2F proteins in cell growth control and apoptosis. Proc. Natl. Acad. Sci. USA. 94:1997;7245-7250.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 7245-7250
-
-
DeGregori, J.1
Leone, G.2
Miron, A.3
Jakoi, L.4
Nevins, J.5
-
9
-
-
0032146274
-
The regulation of E2F by pRB-family proteins
-
Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 12:1998;2245-2262.
-
(1998)
Genes Dev.
, vol.12
, pp. 2245-2262
-
-
Dyson, N.1
-
10
-
-
0024396222
-
Chimaeras between the MYC oncoprotein and sterioid receptors cause hormone-dependent transformation cells
-
Eilers M., Picard D., Yamamoto K., Bishop J.M. Chimaeras between the MYC oncoprotein and sterioid receptors cause hormone-dependent transformation cells. Nature. 340:1989;66-68.
-
(1989)
Nature
, vol.340
, pp. 66-68
-
-
Eilers, M.1
Picard, D.2
Yamamoto, K.3
Bishop, J.M.4
-
11
-
-
0033569422
-
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
-
Eischen C.M., Weber J.D., Roussel M.F., Sherr C.J., Cleveland J.L. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev. 13:1999;2658-2669.
-
(1999)
Genes Dev.
, vol.13
, pp. 2658-2669
-
-
Eischen, C.M.1
Weber, J.D.2
Roussel, M.F.3
Sherr, C.J.4
Cleveland, J.L.5
-
12
-
-
0034953712
-
Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis
-
Eischen C.M., Woo D., Roussel M.F., Cleveland J.L. Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis. Mol. Cell. Biol. 21:2001;5063-5070.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5063-5070
-
-
Eischen, C.M.1
Woo, D.2
Roussel, M.F.3
Cleveland, J.L.4
-
13
-
-
0035882058
-
Deconstructing myc
-
Eisenman R.N. Deconstructing myc. Genes Dev. 15:2001;2023-2030.
-
(2001)
Genes Dev.
, vol.15
, pp. 2023-2030
-
-
Eisenman, R.N.1
-
14
-
-
0035902115
-
Proliferation, cell cycle and apoptosis in cancer
-
Evan G.I., Vousden K.H. Proliferation, cell cycle and apoptosis in cancer. Nature. 411:2001;342-348.
-
(2001)
Nature
, vol.411
, pp. 342-348
-
-
Evan, G.I.1
Vousden, K.H.2
-
15
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
Evan G.I., Wyllie A.H., Gilbert C.S., Littlewood T.D., Land H., Brooks M., Waters C.M., Penn L.Z., Hancock D.C. Induction of apoptosis in fibroblasts by c-myc protein. Cell. 69:1992;119-128.
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
16
-
-
0029949784
-
E2F-1 functions in mice to promote apoptosis and suppress proliferation
-
Field S.J., Tsai F.-Y., Kuo F., Zubiaga A.M., Kaelin W.G., Livingston D.M., Orkin S.H., Greenberg M.E. E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell. 85:1996;549-561.
-
(1996)
Cell
, vol.85
, pp. 549-561
-
-
Field, S.J.1
Tsai, F.-Y.2
Kuo, F.3
Zubiaga, A.M.4
Kaelin, W.G.5
Livingston, D.M.6
Orkin, S.H.7
Greenberg, M.E.8
-
17
-
-
0029779280
-
Cdc25 cell-cycle phosphatase is a target of c-myc
-
Galaktionov K., Chen X., Beach D. Cdc25 cell-cycle phosphatase is a target of c-myc. Nature. 382:1996;511-517.
-
(1996)
Nature
, vol.382
, pp. 511-517
-
-
Galaktionov, K.1
Chen, X.2
Beach, D.3
-
18
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y., Maya R., Kazaz A., Oren M. Mdm2 promotes the rapid degradation of p53. Nature. 387:1997;296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
19
-
-
12944281162
-
Identification of CDK4 as a target of c-MYC
-
Hermeking H., Rago C., Schuhmacher M., Li Q., Barrett J.F., Obaya A.J., O'Connell B.C., Mateyak M.K., Tam W., Kohlhuber F.et al. Identification of CDK4 as a target of c-MYC. Proc. Natl. Acad. Sci. USA. 97:2000;2229-2234.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 2229-2234
-
-
Hermeking, H.1
Rago, C.2
Schuhmacher, M.3
Li, Q.4
Barrett, J.F.5
Obaya, A.J.6
O'Connell, B.C.7
Mateyak, M.K.8
Tam, W.9
Kohlhuber, F.10
-
20
-
-
0034654105
-
E2f3 is critical for normal cellular proliferation
-
Humbert P.O., Verona R., Trimarchi J.M., Rogers C., Dandapani S., Lees J.A. E2f3 is critical for normal cellular proliferation. Genes Dev. 14:2000;690-703.
-
(2000)
Genes Dev.
, vol.14
, pp. 690-703
-
-
Humbert, P.O.1
Verona, R.2
Trimarchi, J.M.3
Rogers, C.4
Dandapani, S.5
Lees, J.A.6
-
21
-
-
0035890273
-
Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas
-
Inoue K., Zindy F., Randle D.H., Rehg J.E., Sherr C.J. Dmp1 is haplo-insufficient for tumor suppression and modifies the frequencies of Arf and p53 mutations in Myc-induced lymphomas. Genes Dev. 15:2001;2934-2939.
-
(2001)
Genes Dev.
, vol.15
, pp. 2934-2939
-
-
Inoue, K.1
Zindy, F.2
Randle, D.H.3
Rehg, J.E.4
Sherr, C.J.5
-
22
-
-
0033569429
-
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc induced apoptosis via INK4a/ARF
-
Jacobs J.J.L., Scheijen B., Vonchen J.-W., Kieboom K., Berns A., van Lohuizen M. Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc induced apoptosis via INK4a/ARF. Genes Dev. 13:1999;2678-2690.
-
(1999)
Genes Dev.
, vol.13
, pp. 2678-2690
-
-
Jacobs, J.J.L.1
Scheijen, B.2
Vonchen, J.-W.3
Kieboom, K.4
Berns, A.5
Van Lohuizen, M.6
-
23
-
-
0033152390
-
C-Myc induced sensitization to apoptosis is mediated through cytochrome c release
-
Juin P., Hueber A.-O., Littlewood T., Evan G. c-Myc induced sensitization to apoptosis is mediated through cytochrome c release. Genes Dev. 13:1999;1367-1381.
-
(1999)
Genes Dev.
, vol.13
, pp. 1367-1381
-
-
Juin, P.1
Hueber, A.-O.2
Littlewood, T.3
Evan, G.4
-
24
-
-
0030728468
-
ARF
-
ARF. Cell. 91:1997;649-659.
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
25
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
Kamijo T., Weber J.D., Zambetti G., Zindy F., Roussel M.F., Sherr C.J. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc. Natl. Acad. Sci. USA. 95:1998;8292-8297.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, F.4
Roussel, M.F.5
Sherr, C.J.6
-
28
-
-
0030995824
-
Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F
-
Leone G., DeGregori J., Sears R., Jakoi L., Nevins J.R. Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F. Nature. 387:1997;422-426.
-
(1997)
Nature
, vol.387
, pp. 422-426
-
-
Leone, G.1
DeGregori, J.2
Sears, R.3
Jakoi, L.4
Nevins, J.R.5
-
29
-
-
17944375816
-
Myc requires distinct E2F activities to induce S phase and apoptosis
-
Leone G., Sears R., Huang E., Rempel R., Nuckolls F., Park C.-H., Giangrande P., Wu L., Saavedra H.I., Field S.J.et al. Myc requires distinct E2F activities to induce S phase and apoptosis. Mol. Cell. 8:2001;105-113.
-
(2001)
Mol. Cell
, vol.8
, pp. 105-113
-
-
Leone, G.1
Sears, R.2
Huang, E.3
Rempel, R.4
Nuckolls, F.5
Park, C.-H.6
Giangrande, P.7
Wu, L.8
Saavedra, H.I.9
Field, S.J.10
-
30
-
-
0034609864
-
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
-
Lissy N.A., Davis P.K., Irwin M., Kaelin W.G., Dowdy S.F. A common E2F-1 and p73 pathway mediates cell death induced by TCR activation. Nature. 407:2000;642-645.
-
(2000)
Nature
, vol.407
, pp. 642-645
-
-
Lissy, N.A.1
Davis, P.K.2
Irwin, M.3
Kaelin, W.G.4
Dowdy, S.F.5
-
31
-
-
0029002136
-
A modified estrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins
-
Littlewood T.D., Hancock D.C., Danielian P.S., Parker M.G., Evan G.I. A modified estrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins. Nucleic Acids Res. 23:1995;1686-1690.
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 1686-1690
-
-
Littlewood, T.D.1
Hancock, D.C.2
Danielian, P.S.3
Parker, M.G.4
Evan, G.I.5
-
32
-
-
0036613246
-
Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry
-
Lomazzi M., Moroni M.C., Jensen M.R., Frittoli E., Helin K. Suppression of the p53- or pRB-mediated G1 checkpoint is required for E2F-induced S-phase entry. Nat. Genet. 31:2002;190-194.
-
(2002)
Nat. Genet.
, vol.31
, pp. 190-194
-
-
Lomazzi, M.1
Moroni, M.C.2
Jensen, M.R.3
Frittoli, E.4
Helin, K.5
-
33
-
-
0035921821
-
A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase
-
Malek N.P., Sundberg H., McGrew S., Nakayama K., Kyriakides T.R., Roberts J.M. A mouse knock-in model exposes sequential proteolytic pathways that regulate p27Kip1 in G1 and S phase. Nature. 413:2001;323-327.
-
(2001)
Nature
, vol.413
, pp. 323-327
-
-
Malek, N.P.1
Sundberg, H.2
McGrew, S.3
Nakayama, K.4
Kyriakides, T.R.5
Roberts, J.M.6
-
35
-
-
0037099496
-
Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis
-
Martins C.P., Berns A. Loss of p27(Kip1) but not p21(Cip1) decreases survival and synergizes with MYC in murine lymphomagenesis. EMBO J. 21:2002;3739-3748.
-
(2002)
EMBO J.
, vol.21
, pp. 3739-3748
-
-
Martins, C.P.1
Berns, A.2
-
36
-
-
0030714114
-
Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes
-
Muller D., Bouchard C., Rudolph B., Steiner P., Stuckmann I., Saffrich R., Ansorge W., Huttner W., Eilers M. Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes. Oncogene. 15:1997;2561-2576.
-
(1997)
Oncogene
, vol.15
, pp. 2561-2576
-
-
Muller, D.1
Bouchard, C.2
Rudolph, B.3
Steiner, P.4
Stuckmann, I.5
Saffrich, R.6
Ansorge, W.7
Huttner, W.8
Eilers, M.9
-
37
-
-
0035063183
-
The Rb/E2F pathway and cancer
-
Nevins J.R. The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10:2001;699-703.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 699-703
-
-
Nevins, J.R.1
-
38
-
-
0037052539
-
A complex with chromatin modifiers that occupies E2F-and Myc-responsive genes in G0 cells
-
Ogawa H., Ishiguro K., Gaubatz S., Livingston D.M., Nakatani Y. A complex with chromatin modifiers that occupies E2F-and Myc-responsive genes in G0 cells. Science. 296:2002;1132-1136.
-
(2002)
Science
, vol.296
, pp. 1132-1136
-
-
Ogawa, H.1
Ishiguro, K.2
Gaubatz, S.3
Livingston, D.M.4
Nakatani, Y.5
-
39
-
-
0033856881
-
Myc-enchanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression
-
O'Hagan R.C., Ohh M., David G., de Alboran I.M., Alt F.W., Kaelin W.G. Jr., DePinho R.A. Myc-enchanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression. Genes Dev. 14:2000;2185-2191.
-
(2000)
Genes Dev.
, vol.14
, pp. 2185-2191
-
-
O'Hagan, R.C.1
Ohh, M.2
David, G.3
De Alboran, I.M.4
Alt, F.W.5
Kaelin W.G., Jr.6
DePinho, R.A.7
-
40
-
-
0032160407
-
Key roles for E2F1 in signaling p53-dependent apoptosis and cell division
-
Pan H., Yin C., Dyson J.J., Harlow E., Yamasaki L., Van Dyke T. Key roles for E2F1 in signaling p53-dependent apoptosis and cell division. Mol. Cell. 2:1998;283-292.
-
(1998)
Mol. Cell
, vol.2
, pp. 283-292
-
-
Pan, H.1
Yin, C.2
Dyson, J.J.3
Harlow, E.4
Yamasaki, L.5
Van Dyke, T.6
-
42
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
Qin X.Q., Livingston D.M., Kaelin W.G. Jr., Adams P.D. Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;10918-10922.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin W.G., Jr.3
Adams, P.D.4
-
43
-
-
0031771497
-
The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53
-
Robertson K.D., Jones P.A. The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol. Cell. Biol. 18:1998;6457-6473.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6457-6473
-
-
Robertson, K.D.1
Jones, P.A.2
-
44
-
-
0036606643
-
Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model
-
Rounbehler R.J., Rogers P.M., Conti C.J., Johnson D.G. Inactivation of E2f1 enhances tumorigenesis in a Myc transgenic model. Cancer Res. 11:2002;3276-3281.
-
(2002)
Cancer Res.
, vol.11
, pp. 3276-3281
-
-
Rounbehler, R.J.1
Rogers, P.M.2
Conti, C.J.3
Johnson, D.G.4
-
46
-
-
0036168192
-
ARF differentially modulates apoptosis induced by E2F1 and Myc
-
Russell J.L., Powers J.T., Rounbehler R.J., Rogers P.M., Conti C.J., Johnson D.G. ARF differentially modulates apoptosis induced by E2F1 and Myc. Mol. Cell. Biol. 22:2002;1360-1368.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1360-1368
-
-
Russell, J.L.1
Powers, J.T.2
Rounbehler, R.J.3
Rogers, P.M.4
Conti, C.J.5
Johnson, D.G.6
-
47
-
-
0035997933
-
Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb
-
Saavedra H.I., Wu L., de Bruin A., Timmers C., Rosol T.J., Weinstein M., Robinson M.L., Leone G. Specificity of E2F1, E2F2, and E2F3 in mediating phenotypes induced by loss of Rb. Cell Growth Differ. 13:2002;215-225.
-
(2002)
Cell Growth Differ.
, vol.13
, pp. 215-225
-
-
Saavedra, H.I.1
Wu, L.2
De Bruin, A.3
Timmers, C.4
Rosol, T.J.5
Weinstein, M.6
Robinson, M.L.7
Leone, G.8
-
48
-
-
0034014307
-
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway
-
Santoni-Rugiu E., Falck J., Mailand N., Bartek J., Lukas J. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway. Mol. Cell. Biol. 20:2000;3497-3509.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 3497-3509
-
-
Santoni-Rugiu, E.1
Falck, J.2
Mailand, N.3
Bartek, J.4
Lukas, J.5
-
49
-
-
0033569423
-
INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53
-
Schmitt C.A., McCurrach M.E., De Stanchina E., Lowe S.W. INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes Dev. 13:1999;2670-2677.
-
(1999)
Genes Dev.
, vol.13
, pp. 2670-2677
-
-
Schmitt, C.A.1
McCurrach, M.E.2
De Stanchina, E.3
Lowe, S.W.4
-
51
-
-
0028061670
-
Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis
-
Shan B., Lee W.H. Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis. Mol. Cell. Biol. 14:1994;8166-8173.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 8166-8173
-
-
Shan, B.1
Lee, W.H.2
-
52
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff R., Groudine M., Gordon M., Roberts J., Clurman B. Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11:1997;1464-1478.
-
(1997)
Genes Dev.
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.1
Groudine, M.2
Gordon, M.3
Roberts, J.4
Clurman, B.5
-
53
-
-
0035487104
-
The INK4a/ARF network in tumour suppression
-
Sherr C.J. The INK4a/ARF network in tumour suppression. Nat. Rev. Mol. Cell Biol. 2:2001;731-737.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 731-737
-
-
Sherr, C.J.1
-
56
-
-
0034092911
-
Regulation of the cdk inhibitor p27 and its deregulation in cancer
-
Slingerland J., Pagano M. Regulation of the cdk inhibitor p27 and its deregulation in cancer. J. Cell. Physiol. 183:2002;10-17.
-
(2002)
J. Cell. Physiol.
, vol.183
, pp. 10-17
-
-
Slingerland, J.1
Pagano, M.2
-
57
-
-
0032169516
-
ARF, participates in a regulatory feedback loop with p53 and MDM2
-
ARF, participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17:1998;5001-5014.
-
(1998)
EMBO J.
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
58
-
-
84883840386
-
Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
-
Todaro G.J., Green H. Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J. Cell Biol. 17:1963;299-313.
-
(1963)
J. Cell Biol.
, vol.17
, pp. 299-313
-
-
Todaro, G.J.1
Green, H.2
-
59
-
-
0036133649
-
ARF is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo
-
ARF is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo. Mol. Cell. Biol. 22:2002;370-377.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 370-377
-
-
Tolbert, D.1
Lu, X.2
Yin, C.3
Tantama, M.4
Van Dyke, T.5
-
61
-
-
0035852632
-
The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex
-
Trimarchi J.M., Fairchild B., Wen J., Lees J.A. The E2F6 transcription factor is a component of the mammalian Bmi1-containing polycomb complex. Proc. Natl. Acad. Sci. USA. 98:2001;1519-1524.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 1519-1524
-
-
Trimarchi, J.M.1
Fairchild, B.2
Wen, J.3
Lees, J.A.4
-
62
-
-
0032159103
-
Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos
-
Tsai K.Y., Hu Y., Macleod K.F., Crowley D., Yamasaki L., Jacks T. Mutation of E2f-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos. Mol. Cell. 2:1998;293-304.
-
(1998)
Mol. Cell
, vol.2
, pp. 293-304
-
-
Tsai, K.Y.1
Hu, Y.2
Macleod, K.F.3
Crowley, D.4
Yamasaki, L.5
Jacks, T.6
-
63
-
-
0037154006
-
ARF is not required for apoptosis in Rb mutant mouse embryos
-
a
-
Tsai K.Y., MacPherson D., Rubinson D.A., Crowley D., Jacks T. ARF is not required for apoptosis in Rb mutant mouse embryos. Curr. Biol. 12:2002;159-163. a.
-
(2002)
Curr. Biol.
, vol.12
, pp. 159-163
-
-
Tsai, K.Y.1
MacPherson, D.2
Rubinson, D.A.3
Crowley, D.4
Jacks, T.5
-
64
-
-
0037168638
-
ARF mutation accelerates pituitary tumor development in Rb+/-mice
-
b
-
Tsai K.Y., MacPherson D., Rubinson D.A., Nikitin A.Y., Bronson R., Mercer K.L., Crowley D., Jacks T. ARF mutation accelerates pituitary tumor development in Rb+/-mice. Proc. Natl. Acad. Sci. USA. 99:2002;16865-16870. b.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 16865-16870
-
-
Tsai, K.Y.1
MacPherson, D.2
Rubinson, D.A.3
Nikitin, A.Y.4
Bronson, R.5
Mercer, K.L.6
Crowley, D.7
Jacks, T.8
-
65
-
-
0344931628
-
CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase
-
Vigo E., Muller H., Prosperini E., Hateboer G., Cartwright P., Moroni M.C., Helin K. CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase. Mol. Cell. Biol. 19:1999;6379-6395.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6379-6395
-
-
Vigo, E.1
Muller, H.2
Prosperini, E.3
Hateboer, G.4
Cartwright, P.5
Moroni, M.C.6
Helin, K.7
-
68
-
-
0028222124
-
P53 and E2F-1 cooperate to mediate apoptosis
-
Wu X., Levine A.J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;3602-3606.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
69
-
-
0035936113
-
The E2F1-3 transcription factors are essential for cellular proliferation
-
Wu L., Timmers C., Maiti B., Saavedra H.I., Sang L., Chong G.T., Nuckolls F., Giangrande P., Wright F.A., Field S.J.et al. The E2F1-3 transcription factors are essential for cellular proliferation. Nature. 414:2001;457-462.
-
(2001)
Nature
, vol.414
, pp. 457-462
-
-
Wu, L.1
Timmers, C.2
Maiti, B.3
Saavedra, H.I.4
Sang, L.5
Chong, G.T.6
Nuckolls, F.7
Giangrande, P.8
Wright, F.A.9
Field, S.J.10
-
70
-
-
0029888359
-
Tumor induction and tissue atrophy in mice lacking E2F-1
-
Yamasaki L., Jacks T., Bronson R., Goillot E., Harlow E., Dyson N.J. Tumor induction and tissue atrophy in mice lacking E2F-1. Cell. 85:1996;537-548.
-
(1996)
Cell
, vol.85
, pp. 537-548
-
-
Yamasaki, L.1
Jacks, T.2
Bronson, R.3
Goillot, E.4
Harlow, E.5
Dyson, N.J.6
-
71
-
-
0031897273
-
Loss of E2F-1 reduces tumorigenesis and extends lifespan of Rb1(+/-) mice
-
Yamasaki L., Bronson R., Williams B.O., Dyson N.J., Harlow E., Jacks T. Loss of E2F-1 reduces tumorigenesis and extends lifespan of Rb1(+/-) mice. Nat. Genet. 18:1998;360-364.
-
(1998)
Nat. Genet.
, vol.18
, pp. 360-364
-
-
Yamasaki, L.1
Bronson, R.2
Williams, B.O.3
Dyson, N.J.4
Harlow, E.5
Jacks, T.6
-
72
-
-
0035967099
-
Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc
-
Yang W., Shen J., Wu M., Arsura M., FitzGerald M., Suldan Z., Kim D.W., Hofmann C.S., Pianetti S., Romieu-Mourez R.et al. Repression of transcription of the p27(Kip1) cyclin-dependent kinase inhibitor gene by c-Myc. Oncogene. 20:2001;1688-1702.
-
(2001)
Oncogene
, vol.20
, pp. 1688-1702
-
-
Yang, W.1
Shen, J.2
Wu, M.3
Arsura, M.4
FitzGerald, M.5
Suldan, Z.6
Kim, D.W.7
Hofmann, C.S.8
Pianetti, S.9
Romieu-Mourez, R.10
-
73
-
-
0035118893
-
E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
-
Ziebold U., Reza T., Caron A., Lees J.A. E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos. Genes Dev. 15:2001;386-391.
-
(2001)
Genes Dev.
, vol.15
, pp. 386-391
-
-
Ziebold, U.1
Reza, T.2
Caron, A.3
Lees, J.A.4
-
74
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization
-
Zindy F., Eischen C.M., Randle D.H., Kamijo T., Cleveland J.L., Sherr C.J., Roussel M.F. Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization. Genes Dev. 12:1998;2424-2433.
-
(1998)
Genes Dev.
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
Kamijo, T.4
Cleveland, J.L.5
Sherr, C.J.6
Roussel, M.F.7
|