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Volumn 2, Issue 6, 2003, Pages 366-374

Adenosine receptors and Huntington's disease: Implications for pathogenesis and therapeutics

Author keywords

[No Author keywords available]

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 5 AMINO 2 (2 FURYL) 7 (2 PHENYLETHYL)PYRAZOLO[4,3 E][1,2,4]TRIAZOLO[1,5 C]PYRIMIDINE; 6 ETHYL 4 PROPYL 2 PHENYL 3 PYRIDINECARBOXYLIC ACID 5 THIOCARBOXYLIC ACID 5 ETHYL 3 PROPYL ESTER; 9 CHLORO 2 (2 FURYL) 5 PHENYLACETYLAMINO 1,2,4 TRIAZOLO[1,5 C]QUINAZOLINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE RECEPTOR; BACLOFEN; DEXTROMETHORPHAN; HUNTINGTIN; ISTRADEFYLLINE; KETAMINE; LAMOTRIGINE; MSX 3; N (4 CYANOPHENYL) 2 [4 (2,3,6,7 TETRAHYDRO 2,6 DIOXO 1,3 DIPROPYL 1H PURIN 8 YL)PHENOXY]ACETAMIDE; PRESYNAPTIC RECEPTOR; RILUZOLE; UNCLASSIFIED DRUG; ZW 241385;

EID: 0038231381     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(03)00411-3     Document Type: Review
Times cited : (118)

References (140)
  • 1
    • 0004293145 scopus 로고    scopus 로고
    • P.S. Harper. London: WB Saunder
    • Harper P.S. Huntington's Disease. 2nd edn:1996;WB Saunder, London.
    • (1996) Huntington's Disease 2nd Edn
  • 3
    • 85056013302 scopus 로고
    • Cortical and striatal neurone number in Huntington's disease
    • Heinsen H., Strik M., Bauer M., et al. Cortical and striatal neurone number in Huntington's disease. Acta Neuropathol (Berl). 88:1994;320-333.
    • (1994) Acta Neuropathol (Berl) , vol.88 , pp. 320-333
    • Heinsen, H.1    Strik, M.2    Bauer, M.3
  • 4
    • 0025885733 scopus 로고
    • Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease
    • Hedreen J.C., Peyser C.E., Folstein S.E., Ross C.A. Neuronal loss in layers V and VI of cerebral cortex in Huntington's disease. Neurosci Lett. 133:1991;257-261.
    • (1991) Neurosci Lett , vol.133 , pp. 257-261
    • Hedreen, J.C.1    Peyser, C.E.2    Folstein, S.E.3    Ross, C.A.4
  • 5
    • 0021028244 scopus 로고
    • A polymorphic DNA marker genetically linked to Huntington's disease
    • Gusella J.F., Wexler N.S., Conneally P.M., et al. A polymorphic DNA marker genetically linked to Huntington's disease. Nature. 306:1983;234-238.
    • (1983) Nature , vol.306 , pp. 234-238
    • Gusella, J.F.1    Wexler, N.S.2    Conneally, P.M.3
  • 6
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell. 72:1993;971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 7
    • 18544410106 scopus 로고    scopus 로고
    • Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
    • Davies S.W., Turmaine M., Cozens B.A., et al. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell. 90:1997;537-548.
    • (1997) Cell , vol.90 , pp. 537-548
    • Davies, S.W.1    Turmaine, M.2    Cozens, B.A.3
  • 9
    • 16044373842 scopus 로고    scopus 로고
    • Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
    • Mangiarini L., Sathasivam K., Seller M., et al. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell. 87:1996;493-506.
    • (1996) Cell , vol.87 , pp. 493-506
    • Mangiarini, L.1    Sathasivam, K.2    Seller, M.3
  • 10
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DiFiglia M., Sapp E., Chase K.O., et al. Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science. 277:1997;1990-1993.
    • (1997) Science , vol.277 , pp. 1990-1993
    • Difiglia, M.1    Sapp, E.2    Chase, K.O.3
  • 11
    • 0036580677 scopus 로고    scopus 로고
    • Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length
    • de Almeida L.P., Ross C.A., Zala D., Aebischer P., Deglon N. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. J Neurosci. 22:2002;3473-3483.
    • (2002) J Neurosci , vol.22 , pp. 3473-3483
    • De Almeida, L.P.1    Ross, C.A.2    Zala, D.3    Aebischer, P.4    Deglon, N.5
  • 12
    • 1542565641 scopus 로고    scopus 로고
    • Lentiviral vectors-mediated gene transfer as a new strategy to model Huntington's disease
    • Amsterdam, Netherlands
    • Deglon N. Lentiviral vectors-mediated gene transfer as a new strategy to model Huntington's disease. 13th Nectar meeting, Amsterdam, Netherlands, 2002.
    • (2002) 13th Nectar Meeting
    • Deglon, N.1
  • 13
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • Saudou F., Finkbeiner S., Devys D., Greenberg M.E. Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell. 95:1998;55-66.
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 14
    • 0033119123 scopus 로고    scopus 로고
    • Nuclear and neuropil aggregates in Huntington's disease: Relationship to neuropathology
    • Gutekunst C.A., Li S.H., Yi H., et al. Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology. J Neurosci. 19:1999;2522-2534.
    • (1999) J Neurosci , vol.19 , pp. 2522-2534
    • Gutekunst, C.A.1    Li, S.H.2    Yi, H.3
  • 15
    • 9344227302 scopus 로고    scopus 로고
    • Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
    • Goldberg Y.P., Nicholson D.W., Rasper D.M., et al. Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract. Nat Genet. 13:1996;442-449.
    • (1996) Nat Genet , vol.13 , pp. 442-449
    • Goldberg, Y.P.1    Nicholson, D.W.2    Rasper, D.M.3
  • 16
    • 0037096376 scopus 로고    scopus 로고
    • Calpain activation in Huntington's disease
    • Gafni J., Ellerby L.M. Calpain activation in Huntington's disease. J Neurosci. 22:2002;4842-4849.
    • (2002) J Neurosci , vol.22 , pp. 4842-4849
    • Gafni, J.1    Ellerby, L.M.2
  • 17
    • 0033136692 scopus 로고    scopus 로고
    • A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
    • Hodgson J.G., Agopyan N., Gutekunst C.A., et al. A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 23:1999;181-192.
    • (1999) Neuron , vol.23 , pp. 181-192
    • Hodgson, J.G.1    Agopyan, N.2    Gutekunst, C.A.3
  • 18
    • 12944263711 scopus 로고    scopus 로고
    • The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
    • Steffan J.S., Kazantsev A., Spasic-Boskovic O., et al. The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription. Proc Natl Acad Sci USA. 97:2000;6763-6768.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6763-6768
    • Steffan, J.S.1    Kazantsev, A.2    Spasic-Boskovic, O.3
  • 19
    • 0032833981 scopus 로고    scopus 로고
    • Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
    • Boutell J.M., Thomas P., Neal J.W., et al. Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin. Hum Mol Genet. 8:1999;1647-1655.
    • (1999) Hum Mol Genet , vol.8 , pp. 1647-1655
    • Boutell, J.M.1    Thomas, P.2    Neal, J.W.3
  • 20
    • 0035937523 scopus 로고    scopus 로고
    • Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
    • Nucifora F.C. Jr, Sasaki M., Peters M.F., et al. Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity. Science. 291:2001;2423-2428.
    • (2001) Science , vol.291 , pp. 2423-2428
    • Nucifora Jr., F.C.1    Sasaki, M.2    Peters, M.F.3
  • 21
    • 0037150687 scopus 로고    scopus 로고
    • Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
    • Dunah A.W., Jeong H., Griffin A., et al. Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease. Science. 296:2002;2238-2243.
    • (2002) Science , vol.296 , pp. 2238-2243
    • Dunah, A.W.1    Jeong, H.2    Griffin, A.3
  • 22
    • 0033614761 scopus 로고    scopus 로고
    • Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease
    • Cha J.H., Frey A.S., Alsdorf S.A., et al. Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease. Philos Trans R Soc Lond B Biol Sci. 354:1999;981-989.
    • (1999) Philos Trans R Soc Lond B Biol Sci , vol.354 , pp. 981-989
    • Cha, J.H.1    Frey, A.S.2    Alsdorf, S.A.3
  • 23
    • 0034283877 scopus 로고    scopus 로고
    • Transcriptional dysregulation in Huntington's disease
    • Cha J.H. Transcriptional dysregulation in Huntington's disease. Trends Neurosci. 23:2000;387-392.
    • (2000) Trends Neurosci , vol.23 , pp. 387-392
    • Cha, J.H.1
  • 24
    • 0033757718 scopus 로고    scopus 로고
    • Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice
    • Dragatsis I., Levine M.S., Zeitlin S. Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice. Nat Genet. 26:2000;300-306.
    • (2000) Nat Genet , vol.26 , pp. 300-306
    • Dragatsis, I.1    Levine, M.S.2    Zeitlin, S.3
  • 25
    • 0035919701 scopus 로고    scopus 로고
    • Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
    • Zuccato C., Ciammola A., Rigamonti D., et al. Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science. 293:2001;493-498.
    • (2001) Science , vol.293 , pp. 493-498
    • Zuccato, C.1    Ciammola, A.2    Rigamonti, D.3
  • 26
    • 0034657112 scopus 로고    scopus 로고
    • Wild-type huntingtin protects from apoptosis upstream of caspase-3
    • Rigamonti D., Bauer J.H., De Fraja C., et al. Wild-type huntingtin protects from apoptosis upstream of caspase-3. J Neurosci. 20:2000;3705-3713.
    • (2000) J Neurosci , vol.20 , pp. 3705-3713
    • Rigamonti, D.1    Bauer, J.H.2    De Fraja, C.3
  • 27
    • 0036173770 scopus 로고    scopus 로고
    • Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi
    • Gervais F.G., Singaraja R., Xanthoudakis S., et al. Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi. Nat Cell Biol. 4:2002;95-105.
    • (2002) Nat Cell Biol , vol.4 , pp. 95-105
    • Gervais, F.G.1    Singaraja, R.2    Xanthoudakis, S.3
  • 29
    • 0032815680 scopus 로고    scopus 로고
    • Replicating Huntington's disease phenotype in experimental animals
    • Brouillet E., Conde F., Beal M.F., Hantraye P. Replicating Huntington's disease phenotype in experimental animals. Prog Neurobiol. 59:1999;427-468.
    • (1999) Prog Neurobiol , vol.59 , pp. 427-468
    • Brouillet, E.1    Conde, F.2    Beal, M.F.3    Hantraye, P.4
  • 30
    • 0034237719 scopus 로고    scopus 로고
    • Energetics in the pathogenesis of neurodegenerative diseases
    • Beal M.F. Energetics in the pathogenesis of neurodegenerative diseases. Trends Neurosci. 23:2000;298-304.
    • (2000) Trends Neurosci. , vol.23 , pp. 298-304
    • Beal, M.F.1
  • 31
    • 0030708576 scopus 로고    scopus 로고
    • Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease: An in situ hybridization study
    • Arzberger T., Krampfl K., Leimgruber S., Weindl A. Changes of NMDA receptor subunit (NR1, NR2B) and glutamate transporter (GLT1) mRNA expression in Huntington's disease: an in situ hybridization study. J Neuropathol Exp Neurol. 56:1997;440-454.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 440-454
    • Arzberger, T.1    Krampfl, K.2    Leimgruber, S.3    Weindl, A.4
  • 32
    • 0033571743 scopus 로고    scopus 로고
    • Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
    • Levine M.S., Klapstein G.J., Koppel A., et al. Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease. J Neurosci Res. 58:1999;515-532.
    • (1999) J Neurosci Res , vol.58 , pp. 515-532
    • Levine, M.S.1    Klapstein, G.J.2    Koppel, A.3
  • 33
    • 0037075624 scopus 로고    scopus 로고
    • Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
    • Zeron M.M., Hansson O., Chen N., et al. Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease. Neuron. 33:2002;849-860.
    • (2002) Neuron , vol.33 , pp. 849-860
    • Zeron, M.M.1    Hansson, O.2    Chen, N.3
  • 34
    • 0036345741 scopus 로고    scopus 로고
    • Impaired glutamate transport and glutamate-glutamine cycling: Downstream effects of the Huntington mutation
    • Behrens P.F., Franz P., Woodman B., Lindenberg K.S., Landwehrmeyer G.B. Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain. 125:2002;1908-1922.
    • (2002) Brain , vol.125 , pp. 1908-1922
    • Behrens, P.F.1    Franz, P.2    Woodman, B.3    Lindenberg, K.S.4    Landwehrmeyer, G.B.5
  • 35
    • 0032851595 scopus 로고    scopus 로고
    • Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
    • Sawa A., Wiegand G.W., Cooper J., et al. Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization. Nat Med. 5:1999;1194-1198.
    • (1999) Nat Med , vol.5 , pp. 1194-1198
    • Sawa, A.1    Wiegand, G.W.2    Cooper, J.3
  • 36
    • 0036327065 scopus 로고    scopus 로고
    • Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
    • Panov A.V., Gutekunst C.A., Leavitt B.R., et al. Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines. Nat Neurosci. 5:2002;731-736.
    • (2002) Nat Neurosci , vol.5 , pp. 731-736
    • Panov, A.V.1    Gutekunst, C.A.2    Leavitt, B.R.3
  • 37
    • 0033954584 scopus 로고    scopus 로고
    • Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases
    • Alexi T., Borlongan C.V., Faull R.L., et al. Neuroprotective strategies for basal ganglia degeneration: Parkinson's and Huntington's diseases. Prog Neurobiol. 60:2000;409-470.
    • (2000) Prog Neurobiol , vol.60 , pp. 409-470
    • Alexi, T.1    Borlongan, C.V.2    Faull, R.L.3
  • 38
    • 0035854087 scopus 로고    scopus 로고
    • Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat
    • Blum D., Gall D., Cuvelier L., Schiffmann S.N. Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat. Neuroreport. 12:2001;1769-1772.
    • (2001) Neuroreport , vol.12 , pp. 1769-1772
    • Blum, D.1    Gall, D.2    Cuvelier, L.3    Schiffmann, S.N.4
  • 39
    • 0035211142 scopus 로고    scopus 로고
    • Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid
    • El Massioui N., Ouary S., Cheruel F., Hantraye P., Brouillet E. Perseverative behavior underlying attentional set-shifting deficits in rats chronically treated with the neurotoxin 3-nitropropionic acid. Exp Neurol. 172:2001;172-181.
    • (2001) Exp Neurol , vol.172 , pp. 172-181
    • El Massioui, N.1    Ouary, S.2    Cheruel, F.3    Hantraye, P.4    Brouillet, E.5
  • 40
    • 0036405496 scopus 로고    scopus 로고
    • Striatal and cortical neurochemical changes induced by chronic metabolic compromise in the 3-nitropropionic model of Huntington's disease
    • Blum D., Galas M.C., Gall D., Cuvelier L., Schiffmann S.N. Striatal and cortical neurochemical changes induced by chronic metabolic compromise in the 3-nitropropionic model of Huntington's disease. Neurobiol Dis. 10:2002;410-426.
    • (2002) Neurobiol Dis , vol.10 , pp. 410-426
    • Blum, D.1    Galas, M.C.2    Gall, D.3    Cuvelier, L.4    Schiffmann, S.N.5
  • 41
    • 0004109776 scopus 로고    scopus 로고
    • L.P. Rowland. Philadelphia: Lippincott Williams and Wilkins
    • Rowland L.P. Merritt's neurology. 10th edn:2000;Lippincott Williams and Wilkins, Philadelphia.
    • (2000) Merritt's Neurology 10th Edn
  • 42
    • 0242432635 scopus 로고    scopus 로고
    • Maintained improvement with minocycline of a patient with advanced Huntington's disease
    • Denovan-Wright E.M., Devarajan S., Dursun S.M., Robertson H.A. Maintained improvement with minocycline of a patient with advanced Huntington's disease. J Psychopharmacol. 16:2002;393-394.
    • (2002) J Psychopharmacol , vol.16 , pp. 393-394
    • Denovan-Wright, E.M.1    Devarajan, S.2    Dursun, S.M.3    Robertson, H.A.4
  • 43
    • 0034979217 scopus 로고    scopus 로고
    • Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease
    • de Almeida L.P., Zala D., Aebischer P., Deglon N. Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. Neurobiol Dis. 8:2001;433-446.
    • (2001) Neurobiol Dis , vol.8 , pp. 433-446
    • De Almeida, L.P.1    Zala, D.2    Aebischer, P.3    Deglon, N.4
  • 44
    • 0034690615 scopus 로고    scopus 로고
    • Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease
    • Mittoux V., Joseph J.M., Conde F., et al. Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease. Hum Gene Ther. 11:2000;1177-1187.
    • (2000) Hum Gene Ther , vol.11 , pp. 1177-1187
    • Mittoux, V.1    Joseph, J.M.2    Conde, F.3
  • 45
    • 0036083379 scopus 로고    scopus 로고
    • The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves huntingtin phosphorylation by Akt
    • Humbert S., Bryson E.A., Cordelieres F.P., et al. The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves huntingtin phosphorylation by Akt. Dev Cell. 2:2002;831-837.
    • (2002) Dev Cell , vol.2 , pp. 831-837
    • Humbert, S.1    Bryson, E.A.2    Cordelieres, F.P.3
  • 46
    • 0034015127 scopus 로고    scopus 로고
    • Fetal tissue transplants in animal models of Huntington's disease: The effects on damaged neuronal circuitry and behavioral deficits
    • Nakao N., Itakura T. Fetal tissue transplants in animal models of Huntington's disease: the effects on damaged neuronal circuitry and behavioral deficits. Prog Neurobiol. 61:2000;313-338.
    • (2000) Prog Neurobiol. , vol.61 , pp. 313-338
    • Nakao, N.1    Itakura, T.2
  • 47
    • 0034627143 scopus 로고    scopus 로고
    • Motor and cognitive improvements in patients with Huntington's disease after neural transplantation
    • Bachoud-Levi A.C., Remy P., Nguyen J.P., et al. Motor and cognitive improvements in patients with Huntington's disease after neural transplantation. Lancet. 356:2000;1975-1979.
    • (2000) Lancet , vol.356 , pp. 1975-1979
    • Bachoud-Levi, A.C.1    Remy, P.2    Nguyen, J.P.3
  • 48
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V., Burnstock G. Receptors for purines and pyrimidines. Pharmacol Rev. 50:1998;413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 49
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie T.V., Masino S.A. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci. 24:2001;31-55.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 50
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm B.B., Ijzerman A.P., Jacobson K.A., Klotz K.N., Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev. 53:2001;527-552.
    • (2001) Pharmacol Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 51
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • Fredholm B.B., Battig K., Holmen J., Nehlig A., Zvartau E.E. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev. 51:1999;83-133.
    • (1999) Pharmacol Rev , vol.51 , pp. 83-133
    • Fredholm, B.B.1    Battig, K.2    Holmen, J.3    Nehlig, A.4    Zvartau, E.E.5
  • 52
    • 49249149792 scopus 로고
    • Are methylxanthine effects due to antagonism of endogenous adenosine?
    • Fredholm B.B. Are methylxanthine effects due to antagonism of endogenous adenosine? Trends Pharmacol Sci. 1:1980;129-132.
    • (1980) Trends Pharmacol Sci , vol.1 , pp. 129-132
    • Fredholm, B.B.1
  • 53
    • 0029885802 scopus 로고    scopus 로고
    • Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
    • Delaney S.M., Geiger J.D. Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation. J Neurosci Methods. 64:1996;151-156.
    • (1996) J Neurosci Methods , vol.64 , pp. 151-156
    • Delaney, S.M.1    Geiger, J.D.2
  • 54
    • 0028351091 scopus 로고
    • Extracellular adenosine concentrations in hippocampal brain slices and the tonic inhibitory modulation of evoked excitatory responses
    • Dunwiddie T.V., Diao L. Extracellular adenosine concentrations in hippocampal brain slices and the tonic inhibitory modulation of evoked excitatory responses. J Pharmacol Exp Ther. 268:1994;537-545.
    • (1994) J Pharmacol Exp Ther , vol.268 , pp. 537-545
    • Dunwiddie, T.V.1    Diao, L.2
  • 55
    • 0033766981 scopus 로고    scopus 로고
    • Extracellular metabolism of ATP and other nucleotides
    • Zimmermann H. Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedebergs Arch Pharmacol. 362:2000;299-309.
    • (2000) Naunyn Schmiedebergs Arch Pharmacol , vol.362 , pp. 299-309
    • Zimmermann, H.1
  • 56
    • 0030875738 scopus 로고    scopus 로고
    • Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus
    • Dunwiddie T.V., Diao L., Proctor W.R. Adenine nucleotides undergo rapid, quantitative conversion to adenosine in the extracellular space in rat hippocampus. J Neurosci. 17:1997;7673-7682.
    • (1997) J Neurosci , vol.17 , pp. 7673-7682
    • Dunwiddie, T.V.1    Diao, L.2    Proctor, W.R.3
  • 57
    • 0031838032 scopus 로고    scopus 로고
    • Levels of endogenous adenosine in rat striatum: I, regulation by ionotropic glutamate receptors, nitric oxide and free radicals
    • Delaney S.M., Shepel P.N., Geiger J.D. Levels of endogenous adenosine in rat striatum: I, regulation by ionotropic glutamate receptors, nitric oxide and free radicals. J Pharmacol Exp Ther. 285:1998;561-567.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 561-567
    • Delaney, S.M.1    Shepel, P.N.2    Geiger, J.D.3
  • 58
    • 0027942571 scopus 로고
    • Release of adenosine by activation of NMDA receptors in the hippocampus
    • Manzoni O.J., Manabe T., Nicoll R.A. Release of adenosine by activation of NMDA receptors in the hippocampus. Science. 265:1994;2098-2101.
    • (1994) Science , vol.265 , pp. 2098-2101
    • Manzoni, O.J.1    Manabe, T.2    Nicoll, R.A.3
  • 60
    • 0033065893 scopus 로고    scopus 로고
    • Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices
    • Latini S., Bordoni F., Pedata F., Corradetti R. Extracellular adenosine concentrations during in vitro ischaemia in rat hippocampal slices. Br J Pharmacol. 127:1999;729-739.
    • (1999) Br J Pharmacol , vol.127 , pp. 729-739
    • Latini, S.1    Bordoni, F.2    Pedata, F.3    Corradetti, R.4
  • 61
    • 0025300578 scopus 로고
    • A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons: Possible relationship with D1 dopamine receptor
    • Schiffmann S.N., Libert F., Vassart G., Dumont J.E., Vanderhaeghen J.J. A cloned G protein-coupled protein with a distribution restricted to striatal medium-sized neurons: possible relationship with D1 dopamine receptor. Brain Res. 519:1990;333-337.
    • (1990) Brain Res , vol.519 , pp. 333-337
    • Schiffmann, S.N.1    Libert, F.2    Vassart, G.3    Dumont, J.E.4    Vanderhaeghen, J.J.5
  • 62
    • 0026396691 scopus 로고
    • Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord
    • Reppert S.M., Weaver D.R., Stehle J.H., Rivkees S.A. Molecular cloning and characterization of a rat A1-adenosine receptor that is widely expressed in brain and spinal cord. Mol Endocrinol. 5:1991;1037-1048.
    • (1991) Mol Endocrinol , vol.5 , pp. 1037-1048
    • Reppert, S.M.1    Weaver, D.R.2    Stehle, J.H.3    Rivkees, S.A.4
  • 63
    • 0028986566 scopus 로고
    • Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia
    • Rivkees S.A., Price S.L., Zhou F.C. Immunohistochemical detection of A1 adenosine receptors in rat brain with emphasis on localization in the hippocampal formation, cerebral cortex, cerebellum, and basal ganglia. Brain Res. 677:1995;193-203.
    • (1995) Brain Res , vol.677 , pp. 193-203
    • Rivkees, S.A.1    Price, S.L.2    Zhou, F.C.3
  • 64
    • 0029666493 scopus 로고    scopus 로고
    • Dopamine D1 receptor-mediated facilitation of GABAergic neurotransmission in the rat strioentopenduncular pathway and its modulation by adenosine A1 receptor-mediated mechanisms
    • Ferre S., O'Connor W.T., Svenningsson P., et al. Dopamine D1 receptor-mediated facilitation of GABAergic neurotransmission in the rat strioentopenduncular pathway and its modulation by adenosine A1 receptor-mediated mechanisms. Suppl Eur J Neurosci. 8:1996;1545-1553.
    • (1996) Suppl Eur J Neurosci , vol.8 , pp. 1545-1553
    • Ferre, S.1    O'Connor, W.T.2    Svenningsson, P.3
  • 65
    • 0023882404 scopus 로고
    • How does adenosine inhibit transmitter release?
    • Fredholm B.B., Dunwiddie T.V. How does adenosine inhibit transmitter release? Trends Pharmacol Sci. 9:1988;130-134.
    • (1988) Trends Pharmacol Sci , vol.9 , pp. 130-134
    • Fredholm, B.B.1    Dunwiddie, T.V.2
  • 66
    • 0026326607 scopus 로고
    • Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: An in situ hybridization histochemistry study
    • Schiffmann S.N., Jacobs O., Vanderhaeghen J.J. Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: an in situ hybridization histochemistry study. J Neurochem. 57:1991;1062-1067.
    • (1991) J Neurochem. , vol.57 , pp. 1062-1067
    • Schiffmann, S.N.1    Jacobs, O.2    Vanderhaeghen, J.J.3
  • 67
    • 0026763441 scopus 로고
    • Molecular cloning of the rat A2 adenosine receptor: Selective co-expression with D2 dopamine receptors in rat striatum
    • Fink J.S., Weaver D.R., Rivkees S.A., et al. Molecular cloning of the rat A2 adenosine receptor: selective co-expression with D2 dopamine receptors in rat striatum. Brain Res Mol Brain Res. 14:1992;186-195.
    • (1992) Brain Res Mol Brain Res , vol.14 , pp. 186-195
    • Fink, J.S.1    Weaver, D.R.2    Rivkees, S.A.3
  • 68
    • 0027339887 scopus 로고
    • Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons
    • Schiffmann S.N., Vanderhaeghen J.J. Adenosine A2 receptors regulate the gene expression of striatopallidal and striatonigral neurons. J Neurosci. 13:1993;1080-1087.
    • (1993) J Neurosci , vol.13 , pp. 1080-1087
    • Schiffmann, S.N.1    Vanderhaeghen, J.J.2
  • 70
    • 0035848459 scopus 로고    scopus 로고
    • Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum
    • Hettinger B.D., Lee A., Linden J., Rosin D.L. Ultrastructural localization of adenosine A2A receptors suggests multiple cellular sites for modulation of GABAergic neurons in rat striatum. J Comp Neurol. 431:2001;331-446.
    • (2001) J Comp Neurol , vol.431 , pp. 331-446
    • Hettinger, B.D.1    Lee, A.2    Linden, J.3    Rosin, D.L.4
  • 71
    • 0036522987 scopus 로고    scopus 로고
    • Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: Possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum
    • Popoli P., Pintor A., Domenici M.R., et al. Blockade of striatal adenosine A2A receptor reduces, through a presynaptic mechanism, quinolinic acid-induced excitotoxicity: possible relevance to neuroprotective interventions in neurodegenerative diseases of the striatum. J Neurosci. 22:2002;1967-1975.
    • (2002) J Neurosci , vol.22 , pp. 1967-1975
    • Popoli, P.1    Pintor, A.2    Domenici, M.R.3
  • 72
    • 0030841177 scopus 로고    scopus 로고
    • Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor
    • Ledent C., Vaugeois J.M., Schiffmann S.N., et al. Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature. 388:1997;674-678.
    • (1997) Nature , vol.388 , pp. 674-678
    • Ledent, C.1    Vaugeois, J.M.2    Schiffmann, S.N.3
  • 73
    • 0035979311 scopus 로고    scopus 로고
    • Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor
    • Johansson B., Halldner L., Dunwiddie T.V., et al. Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor. Proc Natl Acad Sci USA. 98:2001;9407-9412.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9407-9412
    • Johansson, B.1    Halldner, L.2    Dunwiddie, T.V.3
  • 74
    • 0026030658 scopus 로고
    • Postsynaptic dopamine/adenosine interaction: I. Adenosine analogues inhibit dopamine D2-mediated behaviour in short-term reserpinized mice
    • Ferre S., Herrera-Marschitz M., Grabowska-Anden M., Ungerstedt U., Casas M., Anden N.E. Postsynaptic dopamine/adenosine interaction: I. Adenosine analogues inhibit dopamine D2-mediated behaviour in short-term reserpinized mice. Eur J Pharmacol. 192:1991;25-30.
    • (1991) Eur J Pharmacol , vol.192 , pp. 25-30
    • Ferre, S.1    Herrera-Marschitz, M.2    Grabowska-Anden, M.3    Ungerstedt, U.4    Casas, M.5    Anden, N.E.6
  • 75
    • 0030610486 scopus 로고    scopus 로고
    • Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens
    • Svenningsson P., Nomikos G.G., Ongini E., Fredholm B.B. Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens. Neuroscience. 79:1997;753-764.
    • (1997) Neuroscience , vol.79 , pp. 753-764
    • Svenningsson, P.1    Nomikos, G.G.2    Ongini, E.3    Fredholm, B.B.4
  • 76
    • 0035404473 scopus 로고    scopus 로고
    • New aspects of physiological and pathophysiological functions of adenosine A2A receptor in basal ganglia
    • Kase H. New aspects of physiological and pathophysiological functions of adenosine A2A receptor in basal ganglia. Biosci Biotechnol Biochem. 65:2001;1447-1457.
    • (2001) Biosci Biotechnol Biochem , vol.65 , pp. 1447-1457
    • Kase, H.1
  • 77
    • 0034212341 scopus 로고    scopus 로고
    • Neuronal cell death in Huntington's disease: A potential role for dopamine
    • Jakel R.J., Maragos W.F. Neuronal cell death in Huntington's disease: a potential role for dopamine. Trends Neurosci. 23:2000;239-245.
    • (2000) Trends Neurosci , vol.23 , pp. 239-245
    • Jakel, R.J.1    Maragos, W.F.2
  • 79
    • 33845216127 scopus 로고    scopus 로고
    • Adenosine and neuroprotection
    • Fredholm B.B. Adenosine and neuroprotection. Int Rev Neurobiol. 40:1997;259-280.
    • (1997) Int Rev Neurobiol , vol.40 , pp. 259-280
    • Fredholm, B.B.1
  • 80
    • 0028340803 scopus 로고
    • Opposite effects of cyclohexyladenosine and theophylline on hypoxic damage in cultured neurons
    • Daval J.L., Nicolas F. Opposite effects of cyclohexyladenosine and theophylline on hypoxic damage in cultured neurons. Neurosci Lett. 175:1994;114-116.
    • (1994) Neurosci Lett , vol.175 , pp. 114-116
    • Daval, J.L.1    Nicolas, F.2
  • 81
    • 0032555429 scopus 로고    scopus 로고
    • Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures
    • Lynch J.J. III, Alexander K.M., Jarvis M.F., Kowaluk E.A. Inhibition of adenosine kinase during oxygen-glucose deprivation in rat cortical neuronal cultures. Neurosci Lett. 252:1998;207-210.
    • (1998) Neurosci Lett , vol.252 , pp. 207-210
    • Lynch III, J.J.1    Alexander, K.M.2    Jarvis, M.F.3    Kowaluk, E.A.4
  • 82
    • 0030742435 scopus 로고    scopus 로고
    • Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide
    • Barth A., Newell D.W., Nguyen L.B., et al. Neurotoxicity in organotypic hippocampal slices mediated by adenosine analogues and nitric oxide. Brain Res. 762:1997;79-88.
    • (1997) Brain Res , vol.762 , pp. 79-88
    • Barth, A.1    Newell, D.W.2    Nguyen, L.B.3
  • 83
    • 0023692737 scopus 로고
    • Cyclohexyl adenosine protects against neuronal death following ischemia in the CA1 region of gerbil hippocampus
    • Von Lubitz D.K., Dambrosia J.M., Kempski O., Redmond D.J. Cyclohexyl adenosine protects against neuronal death following ischemia in the CA1 region of gerbil hippocampus. Stroke. 19:1988;1133-1139.
    • (1988) Stroke , vol.19 , pp. 1133-1139
    • Von Lubitz, D.K.1    Dambrosia, J.M.2    Kempski, O.3    Redmond, D.J.4
  • 84
    • 0025579957 scopus 로고
    • Cerebral ischemia in gerbils: Postischemic administration of cyclohexyl adenosine and 8-sulfophenyl-theophylline
    • Von Lubitz D.K., Marangos P.J. Cerebral ischemia in gerbils: postischemic administration of cyclohexyl adenosine and 8-sulfophenyl- theophylline. J Mol Neurosci. 2:1990;53-59.
    • (1990) J Mol Neurosci , vol.2 , pp. 53-59
    • Von Lubitz, D.K.1    Marangos, P.J.2
  • 85
    • 0028268303 scopus 로고
    • Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia
    • Von Lubitz D.K., Lin R.C., Melman N., Ji X.D., Carter M.F., Jacobson K.A. Chronic administration of selective adenosine A1 receptor agonist or antagonist in cerebral ischemia. Eur J Pharmacol. 256:1994;161-167.
    • (1994) Eur J Pharmacol , vol.256 , pp. 161-167
    • Von Lubitz, D.K.1    Lin, R.C.2    Melman, N.3    Ji, X.D.4    Carter, M.F.5    Jacobson, K.A.6
  • 87
    • 0026663842 scopus 로고
    • Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: An anatomical and behavioral study
    • Boissard C.G., Lindner M.D., Gribkoff V.K. Hypoxia produces cell death in the rat hippocampus in the presence of an A1 adenosine receptor antagonist: an anatomical and behavioral study. Neuroscience. 48:1992;807-812.
    • (1992) Neuroscience , vol.48 , pp. 807-812
    • Boissard, C.G.1    Lindner, M.D.2    Gribkoff, V.K.3
  • 88
    • 0029417320 scopus 로고
    • The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil
    • Phillis J.W. The effects of selective A1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil. Brain Res. 705:1995;79-84.
    • (1995) Brain Res , vol.705 , pp. 79-84
    • Phillis, J.W.1
  • 89
    • 0024361487 scopus 로고
    • Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain slice
    • Fowler J.C. Adenosine antagonists delay hypoxia-induced depression of neuronal activity in hippocampal brain slice. Brain Res. 490:1989;378-384.
    • (1989) Brain Res , vol.490 , pp. 378-384
    • Fowler, J.C.1
  • 90
    • 0025190225 scopus 로고
    • Adenosine antagonists alter the synaptic response to in vitro ischemia in the rat hippocampus
    • Fowler J.C. Adenosine antagonists alter the synaptic response to in vitro ischemia in the rat hippocampus. Brain Res. 509:1990;331-334.
    • (1990) Brain Res , vol.509 , pp. 331-334
    • Fowler, J.C.1
  • 91
    • 0028172835 scopus 로고
    • Modulation of nerve and glial function by adenosine: Role in the development of ischemic damage
    • Schubert P., Rudolphi K.A., Fredholm B.B., Nakamura Y. Modulation of nerve and glial function by adenosine: role in the development of ischemic damage. Int J Biochem. 26:1994;1227-1236.
    • (1994) Int J Biochem , vol.26 , pp. 1227-1236
    • Schubert, P.1    Rudolphi, K.A.2    Fredholm, B.B.3    Nakamura, Y.4
  • 92
    • 0030061333 scopus 로고    scopus 로고
    • Functional characterization of adenosine receptors in the nucleus tractus solitarius mediating hypotensive responses in the rat
    • White P.J., Rose'Meyer R.B., Hope W. Functional characterization of adenosine receptors in the nucleus tractus solitarius mediating hypotensive responses in the rat. Br J Pharmacol. 117:1996;305-308.
    • (1996) Br J Pharmacol , vol.117 , pp. 305-308
    • White, P.J.1    Rose'Meyer, R.B.2    Hope, W.3
  • 93
    • 0027538536 scopus 로고
    • Purinergic drugs: Opportunities in the 1990s
    • Williams M. Purinergic drugs: opportunities in the 1990s. Drug Res Dev. 28:1993;438-441.
    • (1993) Drug Res Dev , vol.28 , pp. 438-441
    • Williams, M.1
  • 94
    • 0030571556 scopus 로고    scopus 로고
    • Postischemic administration of adenosine amine congener (ADAC): Analysis of recovery in gerbils
    • Von Lubitz D.K., Lin R.C., Paul I.A., et al. Postischemic administration of adenosine amine congener (ADAC): analysis of recovery in gerbils. Eur J Pharmacol. 316:1996;171-179.
    • (1996) Eur J Pharmacol , vol.316 , pp. 171-179
    • Von Lubitz, D.K.1    Lin, R.C.2    Paul, I.A.3
  • 95
    • 0030613748 scopus 로고    scopus 로고
    • Adenosine A1 receptor agonists as clinically viable agents for treatment of ischemic brain disorders
    • Bischofberger N., Jacobson K.A., Von Lubitz D.K. Adenosine A1 receptor agonists as clinically viable agents for treatment of ischemic brain disorders. Ann N Y Acad Sci. 825:1997;23-29.
    • (1997) Ann N Y Acad Sci , vol.825 , pp. 23-29
    • Bischofberger, N.1    Jacobson, K.A.2    Von Lubitz, D.K.3
  • 96
    • 0037107346 scopus 로고    scopus 로고
    • The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity
    • Blum D., Gall D., Galas M.C., d'Alcantara P., Bantubungi K., Schiffmann S.N. The adenosine A1 receptor agonist adenosine amine congener exerts a neuroprotective effect against the development of striatal lesions and motor impairments in the 3-nitropropionic acid model of neurotoxicity. J Neurosci. 22:2002;9122-9133.
    • (2002) J Neurosci , vol.22 , pp. 9122-9133
    • Blum, D.1    Gall, D.2    Galas, M.C.3    D'Alcantara, P.4    Bantubungi, K.5    Schiffmann, S.N.6
  • 97
    • 0035827591 scopus 로고    scopus 로고
    • Protective effect of adenosine receptor agonists in a new model of epilepsy-seizures evoked by mitochondrial toxin, 3-nitropropionic acid, in mice
    • Zuchora B., Turski W.A., Wielosz M., Urbanska E.M. Protective effect of adenosine receptor agonists in a new model of epilepsy-seizures evoked by mitochondrial toxin, 3-nitropropionic acid, in mice. Neurosci Lett. 305:2001;91-94.
    • (2001) Neurosci Lett , vol.305 , pp. 91-94
    • Zuchora, B.1    Turski, W.A.2    Wielosz, M.3    Urbanska, E.M.4
  • 98
    • 0029078855 scopus 로고
    • Inhibition of NMDA receptor-mediated currents in isolated rat hippocampal neurones by adenosine A1 receptor activation
    • de Mendonca A., Sebastiao A.M., Ribeiro J.A. Inhibition of NMDA receptor-mediated currents in isolated rat hippocampal neurones by adenosine A1 receptor activation. Neuroreport. 6:1995;1097-1100.
    • (1995) Neuroreport , vol.6 , pp. 1097-1100
    • De Mendonca, A.1    Sebastiao, A.M.2    Ribeiro, J.A.3
  • 99
    • 0035940687 scopus 로고    scopus 로고
    • Inactivation of adenosine A2A receptor impairs long term potentiation in the accumbens nucleus without altering basal synaptic transmission
    • d'Alcantara P., Ledent C., Swillens S., Schiffmann S.N. Inactivation of adenosine A2A receptor impairs long term potentiation in the accumbens nucleus without altering basal synaptic transmission. Neuroscience. 107:2001;455-464.
    • (2001) Neuroscience , vol.107 , pp. 455-464
    • D'Alcantara, P.1    Ledent, C.2    Swillens, S.3    Schiffmann, S.N.4
  • 100
    • 0031555175 scopus 로고    scopus 로고
    • Adenosine A1 receptor-mediated depression of corticostriatal and thalamostriatal glutamatergic synaptic potentials in vitro
    • Flagmeyer I., Haas H.L., Stevens D.R. Adenosine A1 receptor-mediated depression of corticostriatal and thalamostriatal glutamatergic synaptic potentials in vitro. Brain Res. 778:1997;178-185.
    • (1997) Brain Res , vol.778 , pp. 178-185
    • Flagmeyer, I.1    Haas, H.L.2    Stevens, D.R.3
  • 101
    • 0030764219 scopus 로고    scopus 로고
    • Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats
    • Guyot M.C., Palfi S., Stutzmann J.M., Maziere M., Hantraye P., Brouillet E. Riluzole protects from motor deficits and striatal degeneration produced by systemic 3-nitropropionic acid intoxication in rats. Neuroscience. 81:1997;141-149.
    • (1997) Neuroscience , vol.81 , pp. 141-149
    • Guyot, M.C.1    Palfi, S.2    Stutzmann, J.M.3    Maziere, M.4    Hantraye, P.5    Brouillet, E.6
  • 102
    • 0027433553 scopus 로고
    • Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
    • Beal M.F., Brouillet E., Jenkins B.G., et al. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci. 13:1993;4181-4192.
    • (1993) J Neurosci , vol.13 , pp. 4181-4192
    • Beal, M.F.1    Brouillet, E.2    Jenkins, B.G.3
  • 103
    • 0032479984 scopus 로고    scopus 로고
    • Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist
    • Jones P.A., Smith R.A., Stone T.W. Protection against hippocampal kainate excitotoxicity by intracerebral administration of an adenosine A2A receptor antagonist. Brain Res. 800:1998;328-335.
    • (1998) Brain Res , vol.800 , pp. 328-335
    • Jones, P.A.1    Smith, R.A.2    Stone, T.W.3
  • 104
    • 0033232779 scopus 로고    scopus 로고
    • A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice
    • Chen J.F., Huang Z., Ma J., et al. A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice. J Neurosci. 19:1999;9192-9200.
    • (1999) J Neurosci , vol.19 , pp. 9192-9200
    • Chen, J.F.1    Huang, Z.2    Ma, J.3
  • 105
    • 0032217044 scopus 로고    scopus 로고
    • Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats
    • Monopoli A., Lozza G., Forlani A., Mattavelli A., Ongini E. Blockade of adenosine A2A receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats. Neuroreport. 9:1998;3955-3959.
    • (1998) Neuroreport , vol.9 , pp. 3955-3959
    • Monopoli, A.1    Lozza, G.2    Forlani, A.3    Mattavelli, A.4    Ongini, E.5
  • 106
    • 0037161283 scopus 로고    scopus 로고
    • Caffeinated clues and the promise of adenosine A(2A) antagonists in PD
    • Schwarzschild M.A., Chen J.F., Ascherio A. Caffeinated clues and the promise of adenosine A(2A) antagonists in PD. Neurology. 58:2002;1154-1160.
    • (2002) Neurology , vol.58 , pp. 1154-1160
    • Schwarzschild, M.A.1    Chen, J.F.2    Ascherio, A.3
  • 107
    • 0032781426 scopus 로고    scopus 로고
    • Distribution, biochemistry and function of striatal adenosine A2A receptors
    • Svenningsson P., Le Moine C., Fisone G., Fredholm B.B. Distribution, biochemistry and function of striatal adenosine A2A receptors. Prog Neurobiol. 59:1999;355-396.
    • (1999) Prog Neurobiol , vol.59 , pp. 355-396
    • Svenningsson, P.1    Le Moine, C.2    Fisone, G.3    Fredholm, B.B.4
  • 108
    • 0030615062 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats
    • Fenu S., Pinna A., Ongini E., Morelli M. Adenosine A2A receptor antagonism potentiates L-DOPA-induced turning behaviour and c-fos expression in 6-hydroxydopamine-lesioned rats. Eur J Pharmacol. 321:1997;143-147.
    • (1997) Eur J Pharmacol , vol.321 , pp. 143-147
    • Fenu, S.1    Pinna, A.2    Ongini, E.3    Morelli, M.4
  • 109
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
    • Blum D., Torch S., Lambeng N., et al. Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol. 65:2001;135-172.
    • (2001) Prog Neurobiol , vol.65 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3
  • 110
    • 0344052684 scopus 로고    scopus 로고
    • Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys
    • Grondin R., Bedard P.J., Hadj T.A., Gregoire L., Mori A., Kase H. Antiparkinsonian effect of a new selective adenosine A2A receptor antagonist in MPTP-treated monkeys. Neurology. 52:1999;1673-1677.
    • (1999) Neurology , vol.52 , pp. 1673-1677
    • Grondin, R.1    Bedard, P.J.2    Hadj, T.A.3    Gregoire, L.4    Mori, A.5    Kase, H.6
  • 111
    • 0034711582 scopus 로고    scopus 로고
    • Adenosine A(2A) receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-Parkinsonian rats
    • Koga K., Kurokawa M., Ochi M., Nakamura J., Kuwana Y. Adenosine A(2A) receptor antagonists KF17837 and KW-6002 potentiate rotation induced by dopaminergic drugs in hemi-Parkinsonian rats. Eur J Pharmacol. 408:2000;249-255.
    • (2000) Eur J Pharmacol , vol.408 , pp. 249-255
    • Koga, K.1    Kurokawa, M.2    Ochi, M.3    Nakamura, J.4    Kuwana, Y.5
  • 112
    • 0035874345 scopus 로고    scopus 로고
    • Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease
    • Chen J.F., Xu K., Petzer J.P., et al. Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease. J Neurosci. 21:2001;RC143.
    • (2001) J Neurosci , vol.21 , pp. 143
    • Chen, J.F.1    Xu, K.2    Petzer, J.P.3
  • 113
    • 0036020950 scopus 로고    scopus 로고
    • Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease
    • Ikeda K., Kurokawa M., Aoyama S., Kuwana Y. Neuroprotection by adenosine A2A receptor blockade in experimental models of Parkinson's disease. J Neurochem. 80:2002;262-270.
    • (2002) J Neurochem , vol.80 , pp. 262-270
    • Ikeda, K.1    Kurokawa, M.2    Aoyama, S.3    Kuwana, Y.4
  • 114
    • 0034081681 scopus 로고    scopus 로고
    • The pattern of neurodegeneration in Huntington's disease: A comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease
    • Glass M., Dragunow M., Faull R.L. The pattern of neurodegeneration in Huntington's disease: a comparative study of cannabinoid, dopamine, adenosine and GABA(A) receptor alterations in the human basal ganglia in Huntington's disease. Neuroscience. 97:2000;505-519.
    • (2000) Neuroscience , vol.97 , pp. 505-519
    • Glass, M.1    Dragunow, M.2    Faull, R.L.3
  • 115
    • 0032860432 scopus 로고    scopus 로고
    • The selective vulnerability of striatopallidal neurons
    • Mitchell I.J., Cooper A.J., Griffiths M.R. The selective vulnerability of striatopallidal neurons. Prog Neurobiol. 59:1999;691-719.
    • (1999) Prog Neurobiol , vol.59 , pp. 691-719
    • Mitchell, I.J.1    Cooper, A.J.2    Griffiths, M.R.3
  • 116
    • 0026717486 scopus 로고
    • Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease
    • Albin R.L., Reiner A., Anderson K.D., et al. Preferential loss of striato-external pallidal projection neurons in presymptomatic Huntington's disease. Ann Neurol. 31:1992;425-430.
    • (1992) Ann Neurol , vol.31 , pp. 425-430
    • Albin, R.L.1    Reiner, A.2    Anderson, K.D.3
  • 117
    • 0029586383 scopus 로고
    • Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients
    • Richfield E.K., Maguire-Zeiss K.A., Vonkeman H.E., Voorn P. Preferential loss of preproenkephalin versus preprotachykinin neurons from the striatum of Huntington's disease patients. Ann Neurol. 38:1995;852-861.
    • (1995) Ann Neurol , vol.38 , pp. 852-861
    • Richfield, E.K.1    Maguire-Zeiss, K.A.2    Vonkeman, H.E.3    Voorn, P.4
  • 118
    • 0034048845 scopus 로고    scopus 로고
    • Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease
    • Menalled L., Zanjani H., MacKenzie L., et al. Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease. Exp Neurol. 162:2000;328-342.
    • (2000) Exp Neurol , vol.162 , pp. 328-342
    • Menalled, L.1    Zanjani, H.2    MacKenzie, L.3
  • 119
    • 0035348156 scopus 로고    scopus 로고
    • Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin
    • Varani K., Rigamonti D., Sipione S., et al. Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin. FASEB J. 15:2001;1245-1247.
    • (2001) FASEB J , vol.15 , pp. 1245-1247
    • Varani, K.1    Rigamonti, D.2    Sipione, S.3
  • 120
    • 0032815531 scopus 로고    scopus 로고
    • Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia
    • Bordelon Y.M., Chesselet M.F. Early effects of intrastriatal injections of quinolinic acid on microtubule-associated protein-2 and neuropeptides in rat basal ganglia. Neuroscience. 93:1999;843-853.
    • (1999) Neuroscience , vol.93 , pp. 843-853
    • Bordelon, Y.M.1    Chesselet, M.F.2
  • 121
    • 0025784311 scopus 로고
    • Acute dyskinesias in young asthmatics treated with theophylline
    • Pranzatelli M.R., Albin R.L., Cohen B.H. Acute dyskinesias in young asthmatics treated with theophylline. Pediatr Neurol. 7:1991;216-219.
    • (1991) Pediatr Neurol , vol.7 , pp. 216-219
    • Pranzatelli, M.R.1    Albin, R.L.2    Cohen, B.H.3
  • 122
    • 0027053159 scopus 로고
    • Choreiform movements observed in an 8-year-old child following use of an oral theophylline preparation
    • Stuart A.M., Worley L.M., Spillane J. Choreiform movements observed in an 8-year-old child following use of an oral theophylline preparation. Clin Pediatr (Phila). 31:1992;692-694.
    • (1992) Clin Pediatr (Phila) , vol.31 , pp. 692-694
    • Stuart, A.M.1    Worley, L.M.2    Spillane, J.3
  • 123
    • 0034703569 scopus 로고    scopus 로고
    • CGS 21680 exerts marked antidystonic effects in a genetic model of paroxysmal dyskinesia
    • Richter A., Hamann M., Bartling C. CGS 21680 exerts marked antidystonic effects in a genetic model of paroxysmal dyskinesia. Eur J Pharmacol. 404:2000;299-302.
    • (2000) Eur J Pharmacol , vol.404 , pp. 299-302
    • Richter, A.1    Hamann, M.2    Bartling, C.3
  • 124
    • 0035879332 scopus 로고    scopus 로고
    • Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine
    • Calabresi P., Gubellini P., Picconi B., et al. Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine. J Neurosci. 21:2001;5110-5120.
    • (2001) J Neurosci , vol.21 , pp. 5110-5120
    • Calabresi, P.1    Gubellini, P.2    Picconi, B.3
  • 125
    • 0028972137 scopus 로고
    • Adenosine A2A receptor stimulation enhances striatal extracellular glutamate levels in rats
    • Popoli P., Betto P., Reggio R., Ricciarello G. Adenosine A2A receptor stimulation enhances striatal extracellular glutamate levels in rats. Eur J Pharmacol. 287:1995;215-217.
    • (1995) Eur J Pharmacol , vol.287 , pp. 215-217
    • Popoli, P.1    Betto, P.2    Reggio, R.3    Ricciarello, G.4
  • 127
    • 0034601298 scopus 로고    scopus 로고
    • Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats
    • Corsi C., Melani A., Bianchi L., Pedata F. Striatal A2A adenosine receptor antagonism differentially modifies striatal glutamate outflow in vivo in young and aged rats. Neuroreport. 11:2000;2591-2595.
    • (2000) Neuroreport , vol.11 , pp. 2591-2595
    • Corsi, C.1    Melani, A.2    Bianchi, L.3    Pedata, F.4
  • 128
    • 0035876383 scopus 로고    scopus 로고
    • SCH 58261 (an adenosine A(2A) receptor antagonist) reduces, only at low doses, K(+)-evoked glutamate release in the striatum
    • Pintor A., Quarta D., Pezzola A., Reggio R., Popoli P. SCH 58261 (an adenosine A(2A) receptor antagonist) reduces, only at low doses, K(+)-evoked glutamate release in the striatum. Eur J Pharmacol. 421:2001;177-180.
    • (2001) Eur J Pharmacol , vol.421 , pp. 177-180
    • Pintor, A.1    Quarta, D.2    Pezzola, A.3    Reggio, R.4    Popoli, P.5
  • 129
    • 0035924320 scopus 로고    scopus 로고
    • Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
    • Ohta A., Sitkovsky M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature. 414:2001;916-920.
    • (2001) Nature , vol.414 , pp. 916-920
    • Ohta, A.1    Sitkovsky, M.2
  • 130
    • 0034743760 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage
    • Mayne M., Fotheringham J., Yan H.J., et al. Adenosine A2A receptor activation reduces proinflammatory events and decreases cell death following intracerebral hemorrhage. Ann Neurol. 49:2001;727-735.
    • (2001) Ann Neurol , vol.49 , pp. 727-735
    • Mayne, M.1    Fotheringham, J.2    Yan, H.J.3
  • 131
    • 0035111235 scopus 로고    scopus 로고
    • Early and progressive accumulation of reactive microglia in the Huntington disease brain
    • Sapp E., Kegel K.B., Aronin N., et al. Early and progressive accumulation of reactive microglia in the Huntington disease brain. J Neuropathol Exp Neurol. 60:2001;161-172.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 161-172
    • Sapp, E.1    Kegel, K.B.2    Aronin, N.3
  • 132
    • 0034943057 scopus 로고    scopus 로고
    • Adenosine extracellular brain concentrations and role of A2A receptors in ischemia
    • Pedata F., Corsi C., Melani A., Bordoni F., Latini S. Adenosine extracellular brain concentrations and role of A2A receptors in ischemia. Ann N Y Acad Sci. 939:2001;74-84.
    • (2001) Ann N Y Acad Sci , vol.939 , pp. 74-84
    • Pedata, F.1    Corsi, C.2    Melani, A.3    Bordoni, F.4    Latini, S.5
  • 133
    • 0023255525 scopus 로고
    • Central versus peripheral mediation of responses to adenosine receptor agonists: Evidence against a central mode of action
    • Brodie M.S., Lee K., Fredholm B.B., Stahle L., Dunwiddie T.V. Central versus peripheral mediation of responses to adenosine receptor agonists: evidence against a central mode of action. Brain Res. 415:1987;323-330.
    • (1987) Brain Res , vol.415 , pp. 323-330
    • Brodie, M.S.1    Lee, K.2    Fredholm, B.B.3    Stahle, L.4    Dunwiddie, T.V.5
  • 134
    • 0030737752 scopus 로고    scopus 로고
    • Adenosine as an antiarrhythmic agent
    • Wilbur S.L., Marchlinski F.E. Adenosine as an antiarrhythmic agent. Am J Cardiol. 79:1997;30-37.
    • (1997) Am J Cardiol , vol.79 , pp. 30-37
    • Wilbur, S.L.1    Marchlinski, F.E.2
  • 135
    • 0028849820 scopus 로고
    • Cardiovascular and antilipolytic effects of the adenosine agonist GR79236
    • Merkel L.A., Hawkins E.D., Colussi D.J., et al. Cardiovascular and antilipolytic effects of the adenosine agonist GR79236. Pharmacology. 51:1995;224-236.
    • (1995) Pharmacology , vol.51 , pp. 224-236
    • Merkel, L.A.1    Hawkins, E.D.2    Colussi, D.J.3
  • 136
    • 0027971992 scopus 로고
    • Characterization of the adenosine receptors mediating hypothermia in the conscious mouse
    • Anderson R., Sheehan M.J., Strong P. Characterization of the adenosine receptors mediating hypothermia in the conscious mouse. Br J Pharmacol. 113:1994;1386-1390.
    • (1994) Br J Pharmacol , vol.113 , pp. 1386-1390
    • Anderson, R.1    Sheehan, M.J.2    Strong, P.3
  • 137
    • 0033539040 scopus 로고    scopus 로고
    • N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects
    • Knutsen L.J., Lau J., Petersen H., et al. N-substituted adenosines as novel neuroprotective A(1) agonists with diminished hypotensive effects. J Med Chem. 42:1999;3463-3477.
    • (1999) J Med Chem , vol.42 , pp. 3463-3477
    • Knutsen, L.J.1    Lau, J.2    Petersen, H.3
  • 139
    • 0031594271 scopus 로고    scopus 로고
    • Adenosine A2A antagonist: A novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys
    • Kanda T., Jackson M.J., Smith L.A., et al. Adenosine A2A antagonist: a novel antiparkinsonian agent that does not provoke dyskinesia in parkinsonian monkeys. Ann Neurol. 43:1998;507-513.
    • (1998) Ann Neurol , vol.43 , pp. 507-513
    • Kanda, T.1    Jackson, M.J.2    Smith, L.A.3
  • 140
    • 0030611334 scopus 로고    scopus 로고
    • Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease
    • Richardson P.J., Kase H., Jenner P.G. Adenosine A2A receptor antagonists as new agents for the treatment of Parkinson's disease. Trends Pharmacol Sci. 18:1997;338-344.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 338-344
    • Richardson, P.J.1    Kase, H.2    Jenner, P.G.3


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