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Volumn 8, Issue 9, 1999, Pages 1647-1655

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; CELL NUCLEUS RECEPTOR; GENE PRODUCT; HISTONE DEACETYLASE; HUNTINGTIN; REPRESSOR PROTEIN; RETINOID X RECEPTOR; THYROID HORMONE RECEPTOR;

EID: 0032833981     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/8.9.1647     Document Type: Article
Times cited : (254)

References (59)
  • 1
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington's Disease Collaborative Research Group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell, 72, 971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 0025800526 scopus 로고
    • Androgen receptor gene mutations in x-linked spinal and bulbar muscular atrophy
    • La Spada, A.R., Wilson, E.M., Lubahn, D.B., Harding, A.E. and Fischbeck, K.H. (1991) Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy. Nature, 352, 77-79.
    • (1991) Nature , vol.352 , pp. 77-79
    • La Spada, A.R.1    Wilson, E.M.2    Lubahn, D.B.3    Harding, A.E.4    Fischbeck, K.H.5
  • 11
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neuntes in brain
    • DiFiglia, M., Sapp, E., Chase, K.O., Davies, S.W., Bates, G.P., Vonsattel, J.P. and Aronin, N. (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neuntes in brain. Science, 277, 1990-1993.
    • (1997) Science , vol.277 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 16
    • 0031680014 scopus 로고    scopus 로고
    • A cellular model that recapitulates major pathogenic steps of Huntington's disease
    • Lunke, A. and Mandel, J.-L. (1998) A cellular model that recapitulates major pathogenic steps of Huntington's disease. Hum. Mol. Genet., 7, 1355-1361.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1355-1361
    • Lunke, A.1    Mandel, J.-L.2
  • 17
    • 0032475931 scopus 로고    scopus 로고
    • Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
    • Saudou, F., Finkbeiner, S., Devys, D. and Greenberg, M.E. (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell, 95, 55-66.
    • (1998) Cell , vol.95 , pp. 55-66
    • Saudou, F.1    Finkbeiner, S.2    Devys, D.3    Greenberg, M.E.4
  • 18
    • 0029089172 scopus 로고
    • When more is less: Pathogenesis of glutamine repeat neurodegenerative diseases
    • Ross, C.A. (1995) When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron, 157, 493-496.
    • (1995) Neuron , vol.157 , pp. 493-496
    • Ross, C.A.1
  • 22
    • 0029014180 scopus 로고
    • Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals
    • Servadio, A., Koshy, B., Armstrong, D., Antalffy, B., Orr, H.T. and Zoghbi, H. Y. (1995) Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals. Nature Genet., 10, 94-98.
    • (1995) Nature Genet. , vol.10 , pp. 94-98
    • Servadio, A.1    Koshy, B.2    Armstrong, D.3    Antalffy, B.4    Orr, H.T.5    Zoghbi, H.Y.6
  • 24
    • 0027475093 scopus 로고
    • Androgen receptor and mechanism of androgen action
    • Janne, O.A., Palvimo, J.J., Kallio, P. and Mehto, M. (1993) Androgen receptor and mechanism of androgen action. Ann. Med., 25, 83-89.
    • (1993) Ann. Med. , vol.25 , pp. 83-89
    • Janne, O.A.1    Palvimo, J.J.2    Kallio, P.3    Mehto, M.4
  • 30
    • 0029899868 scopus 로고    scopus 로고
    • Huntingtin-associated protein (HAPl): Discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase
    • Li, X.J., Sharp, A.H., Li, S.H., Dawson, T.M., Snyder, S.H. and Ross, C.A. (1996) Huntingtin-associated protein (HAPl): discrete neuronal localizations in the brain resemble those of neuronal nitric oxide synthase. Proc. Natl Acad. Sci. USA, 93, 39-44.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 39-44
    • Li, X.J.1    Sharp, A.H.2    Li, S.H.3    Dawson, T.M.4    Snyder, S.H.5    Ross, C.A.6
  • 32
    • 0030767266 scopus 로고    scopus 로고
    • Huntingtin-associated protein 1 (HAP1) binds to a trio-like polypeptide,with a rac1 guanine nucleotide exchange factor domain
    • Colomer, V., Engelender, S., Sharp, A.H., Duan, K., Cooper, J.K., Lanahan, A., Lyford, G., Worley, P. and Ross, C.A. (1997) Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide,with a rac1 guanine nucleotide exchange factor domain. Hum. Mol. Genet., 6, 1519-1525.
    • (1997) Hum. Mol. Genet. , vol.6 , pp. 1519-1525
    • Colomer, V.1    Engelender, S.2    Sharp, A.H.3    Duan, K.4    Cooper, J.K.5    Lanahan, A.6    Lyford, G.7    Worley, P.8    Ross, C.A.9
  • 40
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O.K. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340, 245-246.
    • (1989) Nature , vol.340 , pp. 245-246
    • Fields, S.1    Song, O.K.2
  • 44
    • 0031007189 scopus 로고    scopus 로고
    • Histone deacetylase activity is required for full transcriptional repression by mSin3A
    • Hassig, C.A., Fleischer, T.C., Billin, A.N., Schreiber, S.L. and Ayer, D.E. (1997) Histone deacetylase activity is required for full transcriptional repression by mSin3A. Cell, 89, 341-347.
    • (1997) Cell , vol.89 , pp. 341-347
    • Hassig, C.A.1    Fleischer, T.C.2    Billin, A.N.3    Schreiber, S.L.4    Ayer, D.E.5
  • 45
    • 0343924289 scopus 로고    scopus 로고
    • Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
    • Kadosh, D. and Struhl, K. (1997) Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell, 89, 365-371.
    • (1997) Cell , vol.89 , pp. 365-371
    • Kadosh, D.1    Struhl, K.2
  • 46
    • 0030969516 scopus 로고    scopus 로고
    • Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression
    • Laherty, C.D., Yang, W.M., Sun, J.M., Davie, J.R., Seto, E. and Eisenman, R.N. (1997) Histone deacetylases associated with the mSin3 corepressor mediate mad transcriptional repression. Cell, 89, 349-356.
    • (1997) Cell , vol.89 , pp. 349-356
    • Laherty, C.D.1    Yang, W.M.2    Sun, J.M.3    Davie, J.R.4    Seto, E.5    Eisenman, R.N.6
  • 47
    • 0030953186 scopus 로고    scopus 로고
    • Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase
    • Nagy, L., Kao, H.Y., Chakravarti, D., Lin, R.J., Hassig, CA., Ayer, D.E., Schreiber, S.L. and Evans, R.M. (1997) Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell, 89, 373-380.
    • (1997) Cell , vol.89 , pp. 373-380
    • Nagy, L.1    Kao, H.Y.2    Chakravarti, D.3    Lin, R.J.4    Hassig, C.A.5    Ayer, D.E.6    Schreiber, S.L.7    Evans, R.M.8
  • 48
    • 0030916729 scopus 로고    scopus 로고
    • Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex
    • Zhang, Y., Iratni, R., Erdjument-Bromage, H., Tempst, P. and Reinberg, D. (1997) Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex. Cell, 89, 357-364.
    • (1997) Cell , vol.89 , pp. 357-364
    • Zhang, Y.1    Iratni, R.2    Erdjument-Bromage, H.3    Tempst, P.4    Reinberg, D.5
  • 49
    • 0031895798 scopus 로고    scopus 로고
    • Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1
    • Crawford, P.A., Dorn, C., Sadovsky, Y. and Milbrandt, J. (1998) Nuclear receptor DAX-1 recruits nuclear receptor corepressor N-CoR to steroidogenic factor 1. Mol. Cell. Biol., 18, 2949-2956.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2949-2956
    • Crawford, P.A.1    Dorn, C.2    Sadovsky, Y.3    Milbrandt, J.4
  • 51
    • 0030916336 scopus 로고    scopus 로고
    • What's up and down in histone deacetylation and transcription?
    • Pazin, M.J. and Kadonga, J.T. (1997) What's up and down in histone deacetylation and transcription? Cell, 89, 325-328.
    • (1997) Cell , vol.89 , pp. 325-328
    • Pazin, M.J.1    Kadonga, J.T.2
  • 52
    • 0029932598 scopus 로고    scopus 로고
    • A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
    • Taunton, J., Hassig, C.A. and Schreiber, S.L. (1996) A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p. Science, 272, 408-411.
    • (1996) Science , vol.272 , pp. 408-411
    • Taunton, J.1    Hassig, C.A.2    Schreiber, S.L.3
  • 53
    • 0029850458 scopus 로고    scopus 로고
    • Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3
    • Yang, W.M., Inouye, C., Zeng, Y., Bearss, D. and Seto, E. (1996) Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc: Natl Acad. Sci. USA. 93, 12845-12850.
    • (1996) Proc: Natl Acad. Sci. USA , vol.93 , pp. 12845-12850
    • Yang, W.M.1    Inouye, C.2    Zeng, Y.3    Bearss, D.4    Seto, E.5
  • 54
    • 0032526615 scopus 로고    scopus 로고
    • The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70
    • Muscat, G.E., Burke, L.J. and Downes, M. (1998) The corepressor N-CoR and its variants RIP13a and RIP13Delta1 directly interact with the basal transcription factors TFIIB, TAFII32 and TAFII70. Nucleic Acids Res., 26, 2899-2907.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2899-2907
    • Muscat, G.E.1    Burke, L.J.2    Downes, M.3
  • 55
    • 0026060619 scopus 로고
    • RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae
    • Vidai, M. and Gaber, R.F. (1991) RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol., 11, 6317-6327.
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 6317-6327
    • Vidai, M.1    Gaber, R.F.2
  • 59
    • 0029833062 scopus 로고    scopus 로고
    • Spinocerebellar ataxia type-1 and spinobulbar muscular-atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase
    • Koshy, B., Matilla, T., Burright, E.N., Merry, D.E., Fischbeck, K.H., Orr, H.T. and Zoghbi, H.Y. (1996) Spinocerebellar ataxia type-1 and spinobulbar muscular-atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase. Hum. Mol. Genet., 5, 1311-1318
    • (1996) Hum. Mol. Genet. , vol.5 , pp. 1311-1318
    • Koshy, B.1    Matilla, T.2    Burright, E.N.3    Merry, D.E.4    Fischbeck, K.H.5    Orr, H.T.6    Zoghbi, H.Y.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.