Inhibition of mitochondrial complex II induces a long-term potentiation of NMDA-mediated synaptic excitation in the striatum requiring endogenous dopamine

Journal of Neuroscience

Volumn 21, Issue 14, 2001, Pages 5110-5120

  Calabresi, Paolo ^a,b   Gubellini, Paolo ^a,c   Picconi, Barbara ^a,b   Centonze, Diego ^a,b   Pisani, Antonio ^a,b   Bonsi, Paola ^a,b   Greengard, Paul ^d   Hipskind, Robert A ^e   Borrelli, Emiliana ^f   Bernardi, Giorgio ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c CNR   (Italy)

^d ROCKEFELLER UNIVERSITY   (United States)

^e CNRS   (France)

^f INSERM   (France)

Author keywords

D2 dopamine receptors; Excitotoxicity; Huntington's disease; Striatum; Succinate dehydrogenase; Synaptic plasticity

Indexed keywords

3 NITROPROPIONIC ACID; DOPAMINE; DOPAMINE 1 RECEPTOR; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE);

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CHOLINERGIC NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME INHIBITION; HUNTINGTON CHOREA; INTERNEURON; LONG TERM POTENTIATION; MOUSE; NERVE CELL; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

EID: 0035879332     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.21-14-05110.2001     Document Type: Article

References (70)

1. Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons
2. 11C]raclopride-PET studies of the Huntington's disease rate of progression: Relevance of the trinucleotide repeat length
3. Parkinsonian-like locomotor impairment in mice like dopamine D2 receptors
4. Modification of dopamine transporter function: Effect of reactive oxygen species and dopamine
5. Neuronal calcium signaling
6. Chronic systemic pesticide exposure reproduces features of Parkinson's disease
7. 2+ mobilization is strongly potentiated by a parathyroid hormone/cAMP-dependent protein kinase pathway independently of mitogen-activated protein kinase
8. Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia
9. Huntington and DRPLA proteins selectively interact with the enzyme GADPH
10. Lithium treatment blocks long-term synaptic depression in the striatum
11. Electro-physiology of dopamine denervated striatal neurons. Implications for Parkinson's disease
12. Post-receptor mechanisms underlying striatal long-term depression
13. The corticostriatal projection: From synaptic plasticity to dysfunctions of the basal ganglia
14. A field potential analysis on the effects of lamotrigine, GP 47779, and felbamate in neocortical slices
15. Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors
16. Striatal spiny neurons and cholinergic interneurons express differential ionotropic glutamatergic responses and vulnerability: Implications for ischemia and Huntington's disease
17. Activation of M1-like muscarinic receptors is required for the induction of corticostriatal LTP
18. Synaptic transmission in the striatum: From plasticity to neurodegeneration
19. Unilateral dopamine denervation blocks corticostriatal LTP
20. Dopaminergic modulation of NMDA-induced whole cell currents in neostriatal neurons: Contribution of calcium conductances
21. P42/44 MAP kinase inhibitor PD98059 attenuates multiple forms of synaptic plasticity in rat dentate gyrus in vitro
22. Selective sparing of a class of striatal neurons in Huntington's disease
23. Increased cerebrospinal fluid dopamine and 3,4-dihydroxyphenylacetic acid levels in Huntington's disease: Evidence for an overactive dopaminergic brain transmission
24. Calcium signaling in neurons: Molecular mechanisms and cellular consequences
25. Building action repertories: Memory and learning function of the basal ganglia
26. Bioenergetics and glutamate excitotoxicity
27. Inhibition of succinate dehydrogenase by malonic acid produces an "excitotoxic" lesion in rat striatum
28. 3-Nitropropionic acid exacerbates N-methyl-D-aspartate toxicity in striatal culture by multiple mechanisms
29. Mitochondrial defect in Huntington's disease caudate nucleus
30. Transgenic mice expressing a Huntington's disease mutation are resistant to quinolinic acid-induced striatal excitotoxicity
31. 3-calcineurin-signaling cascade
32. Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo
33. A YAC mouse model of Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
34. Dopamine receptors and brain function
35. Neuronal cell death in Huntington's disease: A potential role for dopamine
36. Projection subtypes of rat neostriatal matrix cells revealed by intracellular injection of biocytin
37. Striatal interneurons: Chemical, physiological and morphological characterization
38. A kinase to remember: Dual roles for MAP kinase in long-term memory
39. Activation of mitogen-activated protein kinase in cultured rat hippocampal neurons by stimulation of glutamate receptors
40. Enhanced sensitivity to N-methyl-D-aspartate receptor activation in transgenic and knockin mouse models of Huntington's disease
41. 3-Nitropropionic acid - Exogenous animal neurotoxin and possible human striatal toxin
42. Delayed mitochondrial dysfunction in excitotoxic neuron death: Cytochrome c release and a secondary increase in superoxide production
43. 6-Hydroxydopamine injections into the nigrostriatal pathway attenuate striatal malonate and 3-nitropropionic acid lesions
44. Methylmalonate toxicity in primary neuronal cultures
45. The selective vulnerability of striatopallidal neurons
46. Mitochondria in neurodegeneration: Bioenergetic function in cell life and death
47. Catecholaminergic control of intracellular free calcium and endorphin secretion of rat pituitary intermediate lobe cells
48. Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens
49. Bidirectional regulation of DARPP-32 phosphorylation by dopamine
50. Astroglial trophic support and neuronal cell death: Influence of cellular energy level on type of cell death induced by mitochondrial toxin in cultured rat cortical neurons
51. Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
52. Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
53. Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease
54. Genetic neurodegenerative diseases: The human illness and transgenic models
55. Recent advances in understanding the pathogenesis of Huntington's disease
56. Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease
57. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus
58. Epileptiform discharge induced by 4-aminopyridine in magnesium-free medium in neocortical neurons: Physiological and pharmacological characterization
59. Action of GP 47779, the active metabolite of oxcarbazepine, on the corticostriatal system. II. Modulation of high -voltage-activated calcium currents
60. Membrane potential synchrony of simultaneously recorded striatal spiny neurons in vivo
61. Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus
62. Coordinated expression of dopamine receptors in neostriatal medium spiny neurons
63. The neuronal MAP kinase cascade: A biochemical signal integration system subserving synaptic plasticity and memory
64. 2+ concentration decrease in GH4C1 cell
65. Structure and function of dopamine receptors
66. 3-Nitropropionic acid toxicity in the striatum
67. Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism
68. Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease
69. D(2) dopamine receptors induce mitogen-activated protein kinase and cAMP response element-binding protein phosphorylation in neurons