메뉴 건너뛰기




Volumn 19, Issue 21, 1999, Pages 9192-9200

A(2A) adenosine receptor deficiency attenuates brain injury induced by transient focal ischemia in mice

Author keywords

A(2A) adenosine receptor; Ischemia; Knock out; Neuroprotection; Purine receptor; Stroke

Indexed keywords

ADENOSINE A2A RECEPTOR; RECEPTOR SUBTYPE;

EID: 0033232779     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-21-09192.1999     Document Type: Article
Times cited : (511)

References (53)
  • 1
    • 0030777698 scopus 로고    scopus 로고
    • Mutant mice and neuroscience: Recommendations concerning genetic background
    • Banbury conference on genetic background in mice (1997) Mutant mice and neuroscience: recommendations concerning genetic background. Neuron 19:755-759.
    • (1997) Neuron , vol.19 , pp. 755-759
  • 2
    • 0343852967 scopus 로고    scopus 로고
    • Neonatal cerebral hypoxia ischemia: The effect of adenosine receptor antagonists
    • Bona E, Aden U, Gilland E, Fredholm BB, Hagberg H (1997) Neonatal cerebral hypoxia ischemia: the effect of adenosine receptor antagonists. Neuropharmacology 36:1327-1338.
    • (1997) Neuropharmacology , vol.36 , pp. 1327-1338
    • Bona, E.1    Aden, U.2    Gilland, E.3    Fredholm, B.B.4    Hagberg, H.5
  • 4
    • 0342977733 scopus 로고    scopus 로고
    • Characterization of the genomic structure of mouse A2aR adenosine receptor gene
    • Chen J-F, Fink JS (1996) Characterization of the genomic structure of mouse A2aR adenosine receptor gene. Soc Neurosci Abstr 22:1569.
    • (1996) Soc Neurosci Abstr , vol.22 , pp. 1569
    • Chen, J.-F.1    Fink, J.S.2
  • 5
    • 0032101921 scopus 로고
    • Role of adenosine and its receptors in the vasodilation induced in the cerebral cortex of the rat by systemic hypoxia
    • Lond
    • Coney AM, Marshall JM (1988) Role of adenosine and its receptors in the vasodilation induced in the cerebral cortex of the rat by systemic hypoxia. J Physiol (Lond) 509:507-518.
    • (1988) J Physiol , vol.509 , pp. 507-518
    • Coney, A.M.1    Marshall, J.M.2
  • 7
    • 0027983055 scopus 로고
    • Adenosine, an endogenous anti-inflammatory agent
    • Cronstein BN (1994) Adenosine, an endogenous anti-inflammatory agent. J Appl Physiol 76:5-13.
    • (1994) J Appl Physiol , vol.76 , pp. 5-13
    • Cronstein, B.N.1
  • 8
    • 0028170895 scopus 로고
    • Adenosine-an endogenous neuroprotective metabolite and neuromodulator
    • Deckert J, Gleiter CH (1994) Adenosine-an endogenous neuroprotective metabolite and neuromodulator. J Neural Transm 43:23-31.
    • (1994) J Neural Transm , vol.43 , pp. 23-31
    • Deckert, J.1    Gleiter, C.H.2
  • 13
    • 0028321498 scopus 로고
    • CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischaemic injury in the Mongolian gerbil
    • Gao Y, Phillis JW (1994) CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischaemic injury in the Mongolian gerbil. Life Sci 55:PL61-PL65.
    • (1994) Life Sci , vol.55
    • Gao, Y.1    Phillis, J.W.2
  • 14
    • 0025293685 scopus 로고
    • Neurotransmitters and neuromodulators in the basal ganglia
    • Graybiel AM (1990) Neurotransmitters and neuromodulators in the basal ganglia. Trends Neurosci 13:244-254.
    • (1990) Trends Neurosci , vol.13 , pp. 244-254
    • Graybiel, A.M.1
  • 15
    • 0029977048 scopus 로고    scopus 로고
    • 2A receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals
    • 2A receptor involves activation of both N- and P-type calcium channels by different G proteins and protein kinases in the same striatal nerve terminals. J Neurochem 67:374-381.
    • (1996) J Neurochem , vol.67 , pp. 374-381
    • Gubitz, A.K.1    Widdowson, L.2    Kurokawa, M.3    Kirkpatrick, K.A.4    Richardson, P.J.5
  • 16
    • 0023240964 scopus 로고
    • Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia
    • Hagberg H, Andersson P, Lacarewicz J, Jacobson I, Butcher S, Sandberg M (1987) Extracellular adenosine, inosine, hypoxanthine, and xanthine in relation to tissue nucleotides and purines in rat striatum during transient ischemia. J Neurochem 49:227-231.
    • (1987) J Neurochem , vol.49 , pp. 227-231
    • Hagberg, H.1    Andersson, P.2    Lacarewicz, J.3    Jacobson, I.4    Butcher, S.5    Sandberg, M.6
  • 17
    • 0029976959 scopus 로고    scopus 로고
    • Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion
    • Hara H, Huang PL, Panahian N, Fishman MC, Moskowitz MA (1996) Reduced brain edema and infarction volume in mice lacking the neuronal isoform of nitric oxide synthase after transient MCA occlusion. J Cereb Blood Flow Metab 16:605-611.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 605-611
    • Hara, H.1    Huang, P.L.2    Panahian, N.3    Fishman, M.C.4    Moskowitz, M.A.5
  • 19
    • 0025964894 scopus 로고
    • Effects of topical adenosine analogs and forskolin on rat pial arterioles in vivo
    • Ibayashi S, Ngai AC, Meno JR, Winn HR (1991) Effects of topical adenosine analogs and forskolin on rat pial arterioles in vivo. J Cereb Blood Flow Metab 11:72-76.
    • (1991) J Cereb Blood Flow Metab , vol.11 , pp. 72-76
    • Ibayashi, S.1    Ngai, A.C.2    Meno, J.R.3    Winn, H.R.4
  • 20
    • 0026520040 scopus 로고
    • Adenosine receptors -pharmacology, structure activity relationships, and therapeutic potential
    • Jacobson KA, van Galen, PJ, Williams M (1992) Adenosine receptors -pharmacology, structure activity relationships, and therapeutic potential. J Med Chem 35:407-422.
    • (1992) J Med Chem , vol.35 , pp. 407-422
    • Jacobson, K.A.1    Van Galen, P.J.2    Williams, M.3
  • 24
    • 0030614436 scopus 로고    scopus 로고
    • 2receptor activation attenuates reperfusion injury by inhibiting neutrophil accumulation, superoxide generation and coronary endothelial adherence
    • 2receptor activation attenuates reperfusion injury by inhibiting neutrophil accumulation, superoxide generation and coronary endothelial adherence. J Pharmacol Exp Ther 280:301-309.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 301-309
    • Jordan, J.E.1    Zhao, Z.-Q.2    Sato, H.3    Taft, S.4    Vinten-Johansen, J.5
  • 25
    • 0022496671 scopus 로고
    • Adenosine receptors of cerebral microvessels and choroid plexus
    • Kalaria RN, Harik SI (1986) Adenosine receptors of cerebral microvessels and choroid plexus. J Cereb Blood Flow Metab 6:463-470.
    • (1986) J Cereb Blood Flow Metab , vol.6 , pp. 463-470
    • Kalaria, R.N.1    Harik, S.I.2
  • 27
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R (1992) Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915-926.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 28
    • 0026559157 scopus 로고
    • Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia
    • Matsumoto K, Graf R, Rosner G, Shimada N, Heiss W-D (1992) Flow thresholds for extracellular purine catabolite elevation in cat focal ischemia. Brain Res 579:309-314.
    • (1992) Brain Res , vol.579 , pp. 309-314
    • Matsumoto, K.1    Graf, R.2    Rosner, G.3    Shimada, N.4    Heiss, W.-D.5
  • 29
    • 0032217044 scopus 로고    scopus 로고
    • 2A adenosine receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats
    • 2A adenosine receptors by SCH 58261 results in neuroprotective effects in cerebral ischaemia in rats. NeuroReport 9:3955-3959.
    • (1998) NeuroReport , vol.9 , pp. 3955-3959
    • Monopoli, A.1    Lozza, G.2    Forlani, A.3    Mattavelli, A.4    Ongini, E.5
  • 30
    • 0030200394 scopus 로고    scopus 로고
    • Network-level changes in inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal
    • Moratalla R, Elibol B, Vallejo M, Graybiel AM (1996) Network-level changes in inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal. Neuron 17:147-156.
    • (1996) Neuron , vol.17 , pp. 147-156
    • Moratalla, R.1    Elibol, B.2    Vallejo, M.3    Graybiel, A.M.4
  • 33
    • 0026611117 scopus 로고
    • 2 agonist CGS 21680 enhances excitatory transmitter amino acid release from the ischemic rat cerebral cortex
    • 2 agonist CGS 21680 enhances excitatory transmitter amino acid release from the ischemic rat cerebral cortex. Neurosci Lett 138:169-172.
    • (1992) Neurosci Lett , vol.138 , pp. 169-172
    • O'Regan, M.H.1    Simpson, R.E.2    Perkins, L.M.3    Phillis, J.W.4
  • 34
    • 0030048906 scopus 로고    scopus 로고
    • Characterization and expression of the human A2aR adenosine receptor gene
    • Peterfreund RA, MacCollin M, Gusella J, Fink JS (1996) Characterization and expression of the human A2aR adenosine receptor gene. J Neurochem 66:362-368.
    • (1996) J Neurochem , vol.66 , pp. 362-368
    • Peterfreund, R.A.1    MacCollin, M.2    Gusella, J.3    Fink, J.S.4
  • 35
    • 0024623228 scopus 로고
    • Adenosine in the control of the cerebral circulation
    • Phillis JW (1989) Adenosine in the control of the cerebral circulation. Cerebrovasc Brain Metab Rev 1:26-54.
    • (1989) Cerebrovasc Brain Metab Rev , vol.1 , pp. 26-54
    • Phillis, J.W.1
  • 36
    • 0029417320 scopus 로고
    • 1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil
    • 1 and A2a adenosine receptor antagonists on cerebral ischemic injury in the gerbil. Brain Res 705:79-84.
    • (1995) Brain Res , vol.705 , pp. 79-84
    • Phillis, J.W.1
  • 37
    • 0000467290 scopus 로고    scopus 로고
    • Adenosine agonists and antagonists
    • (Welch KMA, Caplan LR, Reis DJ, Siesjo BK, Weir B, eds). San Diego: Academic
    • Phillis JW (1997) Adenosine agonists and antagonists. In: Primer on cerebrovascular disease (Welch KMA, Caplan LR, Reis DJ, Siesjo BK, Weir B, eds), pp 250-253. San Diego: Academic.
    • (1997) Primer on Cerebrovascular Disease , pp. 250-253
    • Phillis, J.W.1
  • 38
  • 39
    • 0027152254 scopus 로고
    • Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia
    • Pulsinelli W, Sarokin A, Buchan A (1993) Antagonism of the NMDA and non-NMDA receptors in global versus focal brain ischemia. Prog Brain Res 96:125-135.
    • (1993) Prog Brain Res , vol.96 , pp. 125-135
    • Pulsinelli, W.1    Sarokin, A.2    Buchan, A.3
  • 43
    • 0030887853 scopus 로고    scopus 로고
    • Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches
    • Schauwecker PE, Steward O (1997) Genetic determinants of susceptibility to excitotoxic cell death: Implications for gene targeting approaches. Proc Natl Acad Sci USA 94:4103-4108.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4103-4108
    • Schauwecker, P.E.1    Steward, O.2
  • 45
    • 0026326607 scopus 로고
    • Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: An in situ hybridization histochemistry study
    • Schiffmann SN, Jacobs O, Vanderhaeghen J-J (1991) Striatal restricted adenosine A2 receptor (RDC8) is expressed by enkephalin but not by substance P neurons: an in situ hybridization histochemistry study. J Neurochem 57:1062-1067.
    • (1991) J Neurochem , vol.57 , pp. 1062-1067
    • Schiffmann, S.N.1    Jacobs, O.2    Vanderhaeghen, J.-J.3
  • 46
    • 0029665969 scopus 로고    scopus 로고
    • Adenosine A2 receptor-mediated excitatory actions on the nervous system
    • Sebastiao AM, Ribeiro JA (1996) Adenosine A2 receptor-mediated excitatory actions on the nervous system. Prog Neurobiol 48:167-189.
    • (1996) Prog Neurobiol , vol.48 , pp. 167-189
    • Sebastiao, A.M.1    Ribeiro, J.A.2
  • 47
    • 0031466973 scopus 로고    scopus 로고
    • Gene targeting and the biology of learning and memory
    • Silva AJ, Smith AM, Gieses KP (1997) Gene targeting and the biology of learning and memory. Annu Rev Genet 31:527-546.
    • (1997) Annu Rev Genet , vol.31 , pp. 527-546
    • Silva, A.J.1    Smith, A.M.2    Gieses, K.P.3
  • 49
    • 0026711060 scopus 로고
    • Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: Effects of adenosine receptor agonists and antagonists
    • Simpson RE, O'Regan MH, Perkins LM, Phillis JW (1992) Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: effects of adenosine receptor agonists and antagonists. J Neurochem 58:1683-1690.
    • (1992) J Neurochem , vol.58 , pp. 1683-1690
    • Simpson, R.E.1    O'Regan, M.H.2    Perkins, L.M.3    Phillis, J.W.4
  • 51
    • 0003006729 scopus 로고    scopus 로고
    • Adenosine and acute treatment of cerebral ischemia and stroke - "put out more flags."
    • (Jacobson KA, Jarvis MF, eds). New York. Wiley-Liss
    • von Lubitz DJKE (1997) Adenosine and acute treatment of cerebral ischemia and stroke - "put out more flags." In: Purinergic approaches in experimental therapeutics (Jacobson KA, Jarvis MF, eds), pp 449-470. New York. Wiley-Liss.
    • (1997) Purinergic Approaches in Experimental Therapeutics , pp. 449-470
    • Von Lubitz, D.J.K.E.1
  • 53
    • 0027332624 scopus 로고
    • 2A adenosine receptor gene expression in developing rat brain
    • 2A adenosine receptor gene expression in developing rat brain. Brain Res Mol Brain Res 20:313-327.
    • (1993) Brain Res Mol Brain Res , vol.20 , pp. 313-327
    • Weaver, D.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.