Interleukin-7 signaling in human B cell precursor acute lymphoblastic leukemia cells and murine BAF3 cells involves activation of STAT1 and STAT5 mediated via the interleukin-7 receptor α chain

Leukemia

Volumn 10, Issue 8, 1996, Pages 1317-1325

  Van Der Plas, D C ^a   Smiers, F ^a   Pouwels, K ^a   Hoefsloot, L H ^a   Lowenberg B ^a   Touw, I P ^a,b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

BCP ALL; IL 7 receptor; Signal transduction; STAT activation

Indexed keywords

CYTOKINE RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 7; MEMBRANE RECEPTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ALPHA CHAIN; ARTICLE; B LYMPHOCYTE; CELL PROLIFERATION; COMPLEX FORMATION; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STEM CELL;

EID: 0029785520     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Goodwin RG, Lupton S, Schmierer A, Hjerrild KJ, Jerzy R, Clevenger W, Gillis S, Cosman D, Namen AE. Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells. Proc Natl Acad Sci USA 1989; 86: 302-306.
2. Touw I, Pouwels K, van Agthoven T, van Gurp R, Budel L, Hoogerbrugge H, Delwel R, Goodwin R, Namen A, Löwenberg B. Interleukin-7 is a growth factor of precursor B and T acute lymphoblastic leukemia. Blood 1990; 75: 2097-2101.
3. Skjonsberg C, Erikstein BK, Smeland EB, Lie SO, Funderud S, Beiske K, Blomhoff HK. Interleukin-7 differentiates a subgroup of acute lymphoblastic leukemias. Blood 1991; 77: 2445-2450.
4. Smiers FJ, van Paassen M, Pouwels K, Beishuizen A, Hählen K, Löwenberg B, Touw IP. Heterogeneity of proliferative responses of human B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells to interleukin-7 (IL-7): no correlation with immunoglobulin gene status and expression of IL-7 receptor or IL-2/IL-4/IL-7 receptor common γ chain genes. Leukemia 1995; 9: 1039-1045.
5. Taniguchi T. Cytokine signaling through nonreceptor protein tryosine kinases. Science 1995; 268: 251-255.
6. Noguchi M, Nakamura Y, Russell SM, Ziegler SF, Tsang M, Cao X, Leonard WJ. Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor. Science 1993; 262: 1877-1883.
7. Kondo M, Takeshita T, Higuchi M, Nakamura M, Sudo T, Nishikawa S, Sugamura K. Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes. Science 1994; 263: 1453-1454.
8. Russell SM, Keegan AD, Harada N, Nakamura Y, Noguchi M, Leland P, Friedmann MC, Miyajima A, Puri RK, Paul WE, Leonard WJ. Interleukin-2 receptor gamma chain: a functional component of the inlerleukin-4 receptor. Science 1993; 262: 1880-1883.
9. Kondo M, Takeshita T, Ishii N, Nakamura M, Watanabe S, Arai K, Sugamura K. Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. Science 1993; 262: 1874-1877.
10. Kawahara A, Minami Y, Taniguchi T. Evidence for a critical role for the cytoplasmic region of the interleukin 2 (IL-2) receptor gamma chain in IL-2, IL-4, and IL-7 signaling. Mol Cell Biol 1994; 14: 5433-5440.
11. Nakamura Y, Russell SM, Mess SA, Friedmann M, Erdos M, Francois C, Jacques Y, Adelstein S, Leonard WJ. Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signaling. Nature 1994; 369: 330-333.
12. Russell SM, Johnston JA, Noguchi M, Kawamura M, Bacon CM, Friedmann M, Berg M, McVicar DW, Witthuhn BA, Silvennoinen O, Goldman AS, Schmalstieg FC, Ihle JN, O'Shea JJ, Leonard WJ. Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 1994; 266: 1042-1045.
13. Darnell J Jr, Kerr IM, Stark GR. Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins. Science 1994; 264: 1415-1421.
14. Beadling C, Guschin D, Witthuhn BA, Ziemiecki A, Ihle JN, Kerr IM, Cantrell DA. Activation of JAK kinases and STAT proteins by interleukin-2 and interferon alpha, but not the T cell antigen receptor, in human T lymphocytes. EMBO J 1994; 13: 5605-5615.
15. Ihle JN, Witthuhn BA, Quelle FW, Yamamoto K, Thierfelder WE, Kreider B, Silvennoinen O. Signaling by the cytokine receptor superfamily: JAKs and STATs. Trends Biochem Sci 1994; 19: 222-227.
16. Johnston JA, Kawamura M, Kirken RA, Chen YQ, Blake TB, Shibuya K, Ortaldo JR, McVicar DW, O'Shea JJ. Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2. Nature 1994; 370: 151-153.
17. Lamb P, Kessler LV, Suto C, Levy DE, Seidel HM, Stein RB, Rosen J. Rapid activation of proteins that interact with the interferon gamma activation site in response to multiple cytokines. Blood 1994; 83: 2063-2071.
18. Guschin D, Rogers N, Briscoe J, Witthuhn B, Watling D, Horn F, Pellegrini S, Yasukawa K, Heinrich P, Stark GR, Ihle JN, Kerr IM. A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6. EMBO J 1995; 14: 1421-1429.
19. Zheng YX, Takahashi H, Shibata M, Hirokawa K. JAK3 Janus kinase is involved in interleukin-7 signal pathway. FEBS Lett 1994; 353: 289-293.
20. Lin J-X, Mingone T-S, Tsang M, Friedman M, Weatherbee JA, Zhou L, Yamauchi A, Bloom ET, Mietz J, John S, Leonard WJ. The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. Immunity 1995; 2: 331-339.
21. Madsen M, Johnsen HE, Hansen PW, Christiansen SE. Isolation of human T and B lymphocytes by E-rosette gradient centrifugation. Characterization of the isolated subpopulations. J Immunol Meth 1980; 33: 323-326.
22. Skoda RC, Seldin DC, Chiang MK, Peichel CL, Vogt TF, Leder P. Murine c-mpl: a member of the hematopoietic growth factor receptor superfamily that transduces a proliferative signal. EMBO J 1993; 12: 2645-2653.
23. Palacios R, Steinmetz M. IL-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo. Cell 1985; 41: 727-734.
24. Dong F, Brynes RK, Tidow N, Welte K, Löwenberg B, Touw IP. Mutations in the gene for the granulocyte colony-stimulating factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia. New Engl J Med 1995; 333: 487-493.
25. Sadowski HB, Gilman MZ. Cell-free activation of a DNA-binding protein by epidermal growth factor. Nature 1993; 362: 79-83.
26. Wagner BJ, Hayes TE, Hoban CJ, Cochran BH. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J 1990; 9: 4477-4484.
27. Wakao H, Harada N, Kitamura T, Mui AL, Miyajima A. Interleukin-2 and erythropoietin activate STAT5/MGF via distinct pathways. EMBO J 1995; 14: 2527-2535.
28. Wen Z, Zhong Z, Darnell JE. Maximal activation of transcription by Stat1 and Stat3 requires both thyrosine and serine phosphorylation. Cell 1995; 82: 241-250.
29. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen L-A, Norstedt G, Levy D, Groner B. Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO J 1995; 14: 2005-2013.
30. de Koning JP, Dong F, Smith L, Schelen AM, Barge RMY, van der Plas DC, Hoefsloot LH, Löwenberg B, Touw IP. The membrane-distal cytoplasmic region of human granulocyte colony-stimulating factor receptor is required for STAT3, but not STAT1 homodimer formation. Blood 1996; 87: 1335-1342.
31. Era T, Ogawa M, Nishikawa S-I, Okamoto M, Homjo T, Akagi K, Miyazaki J-I, Yamamura K-I. Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin. EMBO J 1991; 10: 337-342.
32. Fujii H, Nakagawa Y, Schindler U, Kawahara A, Mori H, Gouilleux F, Groner B, Ihle JN, Minami Y, Miyazaki T, Taniguchi T. Activation of Stat5 by interleukin-2 requires a carboxy-terminal region of the interleukin-2 receptor β chain but is not essential for the proliferative signal transduction. Proc Natl Acad Sci USA 1995; 92: 5482-5486.
33. fyn through a segment of its cytoplasmic tail. Proc Natl Acad Sci USA 1992; 89: 12083-12087.
34. Venkitaraman AR, Cowling RJ. Interleukin-7 induces the association of phosphatidylinositol 3-kinase with the α chain of the interleukin-7 receptor. Eur J Immunol 1994; 24: 2168-2174.
35. Chiba T, Nagata Y, Machide M, Kishi A, Amanuma H, Sugiyama M, Todokoro K. Tyrosine kinase activation through the extracellular domains of cytokine receptors. Nature 1993; 362: 646-648.
36. Yoshimura A, Todokoro K. Second subunit of Epo receptor? Nature 1994; 372: 137-138.