메뉴 건너뛰기




Volumn 72, Issue 14, 2003, Pages 1549-1561

Molecular mechanisms of corticosteroid actions in chronic inflammatory airway diseases

Author keywords

Coactivators; Corepressors; Glucocorticoids; Mitogen activated protein kinases; Transcription factors

Indexed keywords

CORTICOSTEROID; CYTOPLASMIC RECEPTOR; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR;

EID: 0037458439     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(02)02446-3     Document Type: Short Survey
Times cited : (95)

References (86)
  • 3
    • 0023686772 scopus 로고
    • Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer
    • Akerblom I.E., Slater E.P., Beato M., Baxter J.D., Mellon P.L. Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science. 241:1988;350-353.
    • (1988) Science , vol.241 , pp. 350-353
    • Akerblom, I.E.1    Slater, E.P.2    Beato, M.3    Baxter, J.D.4    Mellon, P.L.5
  • 4
    • 0032940072 scopus 로고    scopus 로고
    • Histone deacetylases: Transcriptional repression with SINers and NuRDs
    • Ayer D.E. Histone deacetylases: transcriptional repression with SINers and NuRDs. Trends in Cell Biology. 9:1999;193-198.
    • (1999) Trends in Cell Biology , vol.9 , pp. 193-198
    • Ayer, D.E.1
  • 5
    • 0035437169 scopus 로고    scopus 로고
    • Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor-κB
    • Ayroldi E., Migliorati G., Bruscoli S., Marchetti C., Zollo O., Cannarile L., D'Adamio F., Riccardi C. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor-κB. Blood. 98:2001;743-753.
    • (2001) Blood , vol.98 , pp. 743-753
    • Ayroldi, E.1    Migliorati, G.2    Bruscoli, S.3    Marchetti, C.4    Zollo, O.5    Cannarile, L.6    D'Adamio, F.7    Riccardi, C.8
  • 6
    • 0030026713 scopus 로고    scopus 로고
    • Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids
    • Bamberger C.M., Schulte H.M., Chrousos G.P. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocrine Reviews. 17:1996;245-261.
    • (1996) Endocrine Reviews , vol.17 , pp. 245-261
    • Bamberger, C.M.1    Schulte, H.M.2    Chrousos, G.P.3
  • 9
    • 0031080138 scopus 로고    scopus 로고
    • NF-κB: A pivotal role in asthma and a new target for therapy
    • Barnes P.J., Adcock I.M. NF-κB: a pivotal role in asthma and a new target for therapy. Trends in Pharmacological Sciences. 18:1997;46-50.
    • (1997) Trends in Pharmacological Sciences , vol.18 , pp. 46-50
    • Barnes, P.J.1    Adcock, I.M.2
  • 12
    • 0033604599 scopus 로고    scopus 로고
    • Therapeutic strategies for allergic diseases
    • Barnes P.J. Therapeutic strategies for allergic diseases. Nature. 402(Supplement):1999;B31-B38.
    • (1999) Nature , vol.402 , Issue.SUPPL.
    • Barnes, P.J.1
  • 13
    • 0034721232 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease
    • Barnes P.J. Chronic obstructive pulmonary disease. New England Journal of Medicine. 343:2000;269-280.
    • (2000) New England Journal of Medicine , vol.343 , pp. 269-280
    • Barnes, P.J.1
  • 15
    • 0025828493 scopus 로고
    • Transcriptional control by nuclear receptors
    • Beato M. Transcriptional control by nuclear receptors. FASEB Journal. 5:1991;2044-2051.
    • (1991) FASEB Journal , vol.5 , pp. 2044-2051
    • Beato, M.1
  • 16
    • 0343985350 scopus 로고    scopus 로고
    • Transcriptional regulation by steroid hormones
    • Beato M., Chavez S., Truss S. Transcriptional regulation by steroid hormones. Steroids. 61:1996;240-251.
    • (1996) Steroids , vol.61 , pp. 240-251
    • Beato, M.1    Chavez, S.2    Truss, S.3
  • 18
    • 0025293278 scopus 로고
    • Post-transcriptional regulation of granulocyte-macrophage colony-stimulating factor synthesis in murine T cells
    • Bickel M., Cohen R.B., Pluznik D.H. Post-transcriptional regulation of granulocyte-macrophage colony-stimulating factor synthesis in murine T cells. Journal of Immunology. 145:1990;840-845.
    • (1990) Journal of Immunology , vol.145 , pp. 840-845
    • Bickel, M.1    Cohen, R.B.2    Pluznik, D.H.3
  • 20
    • 0031455626 scopus 로고    scopus 로고
    • Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway
    • Caelles C., Gonzalez-Sancho J.M., Munoz A. Nuclear hormone receptor antagonism with AP-1 by inhibition of the JNK pathway. Genes & Development. 11:1997;3351-3364.
    • (1997) Genes & Development , vol.11 , pp. 3351-3364
    • Caelles, C.1    Gonzalez-Sancho, J.M.2    Munoz, A.3
  • 21
    • 0027536245 scopus 로고
    • Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma
    • Cembrzynska-Nowak M., Szklarz E., Inglot A.D., Teodorczyk-Injeyan J.A. Elevated release of tumor necrosis factor-alpha and interferon-gamma by bronchoalveolar leukocytes from patients with bronchial asthma. American Review of Respiratory Disease. 147:1993;291-295.
    • (1993) American Review of Respiratory Disease , vol.147 , pp. 291-295
    • Cembrzynska-Nowak, M.1    Szklarz, E.2    Inglot, A.D.3    Teodorczyk-Injeyan, J.A.4
  • 22
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L., Karin M. Mammalian MAP kinase signalling cascades. Nature. 410:2001;37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 23
    • 0034636021 scopus 로고    scopus 로고
    • Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
    • De Bosscher K., Vanden Berghe W., Vermeulen L., Plaisance S., Boone E., Haegeman G. Glucocorticoids repress NF-κB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell. Proceedings of the National Academy of Sciences USA. 97:2000;3919-3924.
    • (2000) Proceedings of the National Academy of Sciences USA , vol.97 , pp. 3919-3924
    • De Bosscher, K.1    Vanden Berghe, W.2    Vermeulen, L.3    Plaisance, S.4    Boone, E.5    Haegeman, G.6
  • 25
    • 0033161645 scopus 로고    scopus 로고
    • Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle
    • Fernandes D., Guida E., Koutsoubos V., Harris T., Vadiveloo P., Wilson J.W., Stewart A.G. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 21:1999;77-88.
    • (1999) American Journal of Respiratory Cell and Molecular Biology , vol.21 , pp. 77-88
    • Fernandes, D.1    Guida, E.2    Koutsoubos, V.3    Harris, T.4    Vadiveloo, P.5    Wilson, J.W.6    Stewart, A.G.7
  • 27
  • 28
    • 0034650893 scopus 로고    scopus 로고
    • The coregulator exchange in transcriptional functions of nuclear receptors
    • Glass C.K., Rosenfeld M.G. The coregulator exchange in transcriptional functions of nuclear receptors. Genes and Development. 14:2000;121-141.
    • (2000) Genes and Development , vol.14 , pp. 121-141
    • Glass, C.K.1    Rosenfeld, M.G.2
  • 29
    • 0344423816 scopus 로고    scopus 로고
    • Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells
    • Gonzalez M.V., Gonzalez-Sancho J.M., Caelles C., Munoz A., Jimenez B. Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells. FEBS Letters. 459:1999;272-276.
    • (1999) FEBS Letters , vol.459 , pp. 272-276
    • Gonzalez, M.V.1    Gonzalez-Sancho, J.M.2    Caelles, C.3    Munoz, A.4    Jimenez, B.5
  • 30
    • 0026754249 scopus 로고
    • Control of transcription activation by steroid hormone receptors
    • Gronemeyer H. Control of transcription activation by steroid hormone receptors. FASEB Journal. 6:1992;2524-2529.
    • (1992) FASEB Journal , vol.6 , pp. 2524-2529
    • Gronemeyer, H.1
  • 34
    • 0032054723 scopus 로고    scopus 로고
    • Signal transduction by the c-Jun N-terminal kinase (JNK): From inflammation to development
    • Ip Y.T., Davis R.J. Signal transduction by the c-Jun N-terminal kinase (JNK): from inflammation to development. Current Opinion in Cell Biology. 10:1998;205-219.
    • (1998) Current Opinion in Cell Biology , vol.10 , pp. 205-219
    • Ip, Y.T.1    Davis, R.J.2
  • 35
  • 36
    • 0033821409 scopus 로고    scopus 로고
    • Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12
    • Ito K., Barnes P.J., Adcock I.M. Glucocorticoid receptor recruitment of histone deacetylase 2 inhibits interleukin-1β-induced histone H4 acetylation on lysines 8 and 12. Molecular Cell Biology. 20:2000;6891-6903.
    • (2000) Molecular Cell Biology , vol.20 , pp. 6891-6903
    • Ito, K.1    Barnes, P.J.2    Adcock, I.M.3
  • 37
    • 0035315925 scopus 로고    scopus 로고
    • Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages
    • Ito K., Lim S., Caramori G., Chung K.F., Barnes P.J., Adcock I.M. Cigarette smoking reduces histone deacetylase 2 expression, enhances cytokine expression, and inhibits glucocorticoid actions in alveolar macrophages. FASEB Journal. 15:2001;1110-1112.
    • (2001) FASEB Journal , vol.15 , pp. 1110-1112
    • Ito, K.1    Lim, S.2    Caramori, G.3    Chung, K.F.4    Barnes, P.J.5    Adcock, I.M.6
  • 38
    • 0031954369 scopus 로고    scopus 로고
    • Structural and inflammatory changes in COPD: A comparison with asthma
    • Jeffery P.K. Structural and inflammatory changes in COPD: a comparison with asthma. Thorax. 53:1998;129-136.
    • (1998) Thorax , vol.53 , pp. 129-136
    • Jeffery, P.K.1
  • 39
    • 0037126628 scopus 로고    scopus 로고
    • Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
    • Kassel O., Sancono A., Kratzschmar J., Kreft B., Stassen M., Cato A.C. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO Journal. 20:2001;7108-7116.
    • (2001) EMBO Journal , vol.20 , pp. 7108-7116
    • Kassel, O.1    Sancono, A.2    Kratzschmar, J.3    Kreft, B.4    Stassen, M.5    Cato, A.C.6
  • 40
    • 0023906367 scopus 로고
    • Dexamethasone inhibition of interleukin-1β production by human monocytes. Posttranscriptional mechanisms
    • Kern J.A., Lamb R.J., Reed J.C., Daniele R.P., Nowell P.C. Dexamethasone inhibition of interleukin-1β production by human monocytes. Posttranscriptional mechanisms. Journal of Clinical Investigation. 81:1988;237-244.
    • (1988) Journal of Clinical Investigation , vol.81 , pp. 237-244
    • Kern, J.A.1    Lamb, R.J.2    Reed, J.C.3    Daniele, R.P.4    Nowell, P.C.5
  • 41
    • 0032535369 scopus 로고    scopus 로고
    • Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
    • Lane S.J., Adcock I.M., Richards D., Hawrylowicz C., Barnes P.J., Lee T.H. Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes. Journal of Clinical Investigation. 102:1998;2156-2164.
    • (1998) Journal of Clinical Investigation , vol.102 , pp. 2156-2164
    • Lane, S.J.1    Adcock, I.M.2    Richards, D.3    Hawrylowicz, C.4    Barnes, P.J.5    Lee, T.H.6
  • 42
    • 0035138742 scopus 로고    scopus 로고
    • Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38
    • Lasa M., Brook M., Saklatvala J., Clark A.R. Dexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38. Molecular Cell Biology. 31:2001;771-780.
    • (2001) Molecular Cell Biology , vol.31 , pp. 771-780
    • Lasa, M.1    Brook, M.2    Saklatvala, J.3    Clark, A.R.4
  • 43
    • 0025780755 scopus 로고
    • Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
    • Luisi B.F., Xu W.X., Otwinowski Z., Freedman L.P., Yamamoto K.R. Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA. Nature. 352:1991;497-505.
    • (1991) Nature , vol.352 , pp. 497-505
    • Luisi, B.F.1    Xu, W.X.2    Otwinowski, Z.3    Freedman, L.P.4    Yamamoto, K.R.5
  • 45
    • 0033304494 scopus 로고    scopus 로고
    • Molecular control of immune/inflammatory responses: Interactions between nuclear factor-κB and steroid receptor-signaling pathways
    • McKay L.I., Cidlowski J.A. Molecular control of immune/inflammatory responses: interactions between nuclear factor-κB and steroid receptor-signaling pathways. Endocrine Reviews. 20:1999;435-459.
    • (1999) Endocrine Reviews , vol.20 , pp. 435-459
    • McKay, L.I.1    Cidlowski, J.A.2
  • 46
    • 0034464826 scopus 로고    scopus 로고
    • CBP (CREB binding protein) integrates NF-κB (nuclear factor-κB) and glucocorticoid receptor physical interactions and antagonism
    • McKay L.I., Cidlowski J.A. CBP (CREB binding protein) integrates NF-κB (nuclear factor-κB) and glucocorticoid receptor physical interactions and antagonism. Molecular Endocrinology. 14:2000;1222-1234.
    • (2000) Molecular Endocrinology , vol.14 , pp. 1222-1234
    • McKay, L.I.1    Cidlowski, J.A.2
  • 47
    • 0024396320 scopus 로고
    • Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins
    • Mitchell P.J., Tjian R. Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins. Science. 245:1989;371-378.
    • (1989) Science , vol.245 , pp. 371-378
    • Mitchell, P.J.1    Tjian, R.2
  • 48
    • 0032429910 scopus 로고    scopus 로고
    • Glucocorticoids inhibit IL-4 and mitogen-induced IL-4Rα chain expression by different post-transcriptional mechanisms
    • Mozo L., Gayo A., Suarez A., Rivas D., Zamorano J., Gutierrez C. Glucocorticoids inhibit IL-4 and mitogen-induced IL-4Rα chain expression by different post-transcriptional mechanisms. Journal of Allergy and Clinical Immunology. 102:1998;968-976.
    • (1998) Journal of Allergy and Clinical Immunology , vol.102 , pp. 968-976
    • Mozo, L.1    Gayo, A.2    Suarez, A.3    Rivas, D.4    Zamorano, J.5    Gutierrez, C.6
  • 49
    • 0141835487 scopus 로고    scopus 로고
    • Bethesda: U.S. Department of Health and Human Services, National Heart, Lung, and Blood Institute, publication no. 97-4051
    • Guidelines for the diagnosis and management of asthma: expert panel report 2. 1997;U.S. Department of Health and Human Services, National Heart, Lung, and Blood Institute, publication no. 97-4051, Bethesda.
    • (1997) Guidelines for the diagnosis and management of asthma: Expert panel report 2
  • 50
    • 0033610923 scopus 로고    scopus 로고
    • Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA
    • Newton R., Seybold J., Kuttert L.M., Bergmann M., Barnes P.J. Repression of cyclooxygenase-2 and prostaglandin E2 release by dexamethasone occurs by transcriptional and post-transcriptional mechanisms involving loss of polyadenylated mRNA. Journal of Biological Chemistry. 273:1998;32312-32321.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 32312-32321
    • Newton, R.1    Seybold, J.2    Kuttert, L.M.3    Bergmann, M.4    Barnes, P.J.5
  • 51
    • 34147214922 scopus 로고    scopus 로고
    • Bethesda: U.S. Department of Health and Human Services, National Heart, Lung, and Blood Institute, NIH publication no. 2701
    • Global strategy for the diagnosis, management, and prevention of COPD. 2001;U.S. Department of Health and Human Services, National Heart, Lung, and Blood Institute, NIH publication no. 2701, Bethesda.
    • (2001) Global strategy for the diagnosis, management, and prevention of COPD
  • 52
    • 0032525139 scopus 로고    scopus 로고
    • Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin
    • Nightingale K.P., Wellinger R.E., Sogo J.M., Becker P.B. Histone acetylation facilitates RNA polymerase II transcription of the Drosophila hsp26 gene in chromatin. EMBO Journal. 17:1998;2865-2876.
    • (1998) EMBO Journal , vol.17 , pp. 2865-2876
    • Nightingale, K.P.1    Wellinger, R.E.2    Sogo, J.M.3    Becker, P.B.4
  • 54
    • 0034665748 scopus 로고    scopus 로고
    • The glucocorticoid receptor inhibits NF-κB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
    • Nissen R.M., Yamamoto K.R. The glucocorticoid receptor inhibits NF-κB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes & Development. 14:2000;2314-2329.
    • (2000) Genes & Development , vol.14 , pp. 2314-2329
    • Nissen, R.M.1    Yamamoto, K.R.2
  • 56
    • 0028234712 scopus 로고
    • 2-adrenergic receptors and the implications for bronchial asthma: An update
    • 2-adrenergic receptors and the implications for bronchial asthma: an update. Monaldi Archives for Chest Disease. 49:1994;125-130.
    • (1994) Monaldi Archives for Chest Disease , vol.49 , pp. 125-130
    • Pelaia, G.1    Marsico, S.A.2
  • 59
    • 0026100340 scopus 로고
    • The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids
    • Peppel K., Vinci J.M., Baglioni C. The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids. Journal of Experimental Medicine. 173:1991;349-355.
    • (1991) Journal of Experimental Medicine , vol.173 , pp. 349-355
    • Peppel, K.1    Vinci, J.M.2    Baglioni, C.3
  • 61
    • 0027521592 scopus 로고
    • Nuclear receptor/AP-1 interaction
    • Pfahl M. Nuclear receptor/AP-1 interaction. Endocrine Reviews. 14:1993;651-658.
    • (1993) Endocrine Reviews , vol.14 , pp. 651-658
    • Pfahl, M.1
  • 62
    • 0031840980 scopus 로고    scopus 로고
    • Role of transcription factors in inflammatory lung diseases
    • Rahman I., MacNee W. Role of transcription factors in inflammatory lung diseases. Thorax. 53:1998;601-612.
    • (1998) Thorax , vol.53 , pp. 601-612
    • Rahman, I.1    MacNee, W.2
  • 63
    • 0033806242 scopus 로고    scopus 로고
    • Oxidative stress and regulation of glutathione in lung inflammation
    • Rahman I., MacNee W. Oxidative stress and regulation of glutathione in lung inflammation. European Respiratory Journal. 16:2000;534-554.
    • (2000) European Respiratory Journal , vol.16 , pp. 534-554
    • Rahman, I.1    MacNee, W.2
  • 64
    • 0036710706 scopus 로고    scopus 로고
    • Oxidative stress, transcription factors and chromatin remodeling in lung inflammation
    • Rahman I. Oxidative stress, transcription factors and chromatin remodeling in lung inflammation. Biochemical Pharmacology. 64:2002;935-942.
    • (2002) Biochemical Pharmacology , vol.64 , pp. 935-942
    • Rahman, I.1
  • 65
    • 0025047444 scopus 로고
    • On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: Enhancer, TATA box, and RNA start site (Inr motif) occlusion
    • Ray A., LaForge K.S., Sehgal P.B. On the mechanism for efficient repression of the interleukin-6 promoter by glucocorticoids: enhancer, TATA box, and RNA start site (Inr motif) occlusion. Molecular and Cell Biology. 10:1990;5736-5746.
    • (1990) Molecular and Cell Biology , vol.10 , pp. 5736-5746
    • Ray, A.1    LaForge, K.S.2    Sehgal, P.B.3
  • 66
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
    • Ray A., Prefontaine K.E. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proceedings of the National Academy of Sciences USA. 91:1994;752-756.
    • (1994) Proceedings of the National Academy of Sciences USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 68
    • 0033399323 scopus 로고    scopus 로고
    • Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: Role of GITR and GILZ, two dexamethasone-induced genes
    • Riccardi C., Cifone M.G., Migliorati G. Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes. Cell Death and Differentiation. 6:1999;1182-1189.
    • (1999) Cell Death and Differentiation , vol.6 , pp. 1182-1189
    • Riccardi, C.1    Cifone, M.G.2    Migliorati, G.3
  • 69
    • 0030587114 scopus 로고    scopus 로고
    • Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells
    • Rider L.G., Hirasawa N., Santini F., Beaven M.A. Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells. Journal of Immunology. 157:1996;2374-2380.
    • (1996) Journal of Immunology , vol.157 , pp. 2374-2380
    • Rider, L.G.1    Hirasawa, N.2    Santini, F.3    Beaven, M.A.4
  • 72
    • 0027447541 scopus 로고
    • Steroid receptors and their associated proteins
    • Smith D.F., Toft D.O. Steroid receptors and their associated proteins. Molecular Endocrinology. 7:1993;4-11.
    • (1993) Molecular Endocrinology , vol.7 , pp. 4-11
    • Smith, D.F.1    Toft, D.O.2
  • 73
    • 0032742092 scopus 로고    scopus 로고
    • Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3
    • Song C.-Z., Tian X., Gelehrter T.D. Glucocorticoid receptor inhibits transforming growth factor-β signaling by directly targeting the transcriptional activation function of Smad3. Proceedings of the National Academy of Sciences USA. 96:1999;11776-11781.
    • (1999) Proceedings of the National Academy of Sciences USA , vol.96 , pp. 11776-11781
    • Song, C.-Z.1    Tian, X.2    Gelehrter, T.D.3
  • 74
    • 0032843944 scopus 로고    scopus 로고
    • In vivo resistance to corticosteroids in bronchial asthma is associated with enhanced phosphorylation of Jun N-terminal kinase and failure of prednisolone to inhibit Jun N-terminal kinase phosphorylation
    • Sousa A.R., Lane S.J., Soh C., Lee T.H. In vivo resistance to corticosteroids in bronchial asthma is associated with enhanced phosphorylation of Jun N-terminal kinase and failure of prednisolone to inhibit Jun N-terminal kinase phosphorylation. Journal of Allergy and Clinical Immunology. 104:1999;565-574.
    • (1999) Journal of Allergy and Clinical Immunology , vol.104 , pp. 565-574
    • Sousa, A.R.1    Lane, S.J.2    Soh, C.3    Lee, T.H.4
  • 75
    • 0029851231 scopus 로고    scopus 로고
    • Functional interactions between Stat5 and the glucocorticoid receptor
    • Stoecklin E., Wissler M., Gouilleux F., Groner B. Functional interactions between Stat5 and the glucocorticoid receptor. Nature. 383:1996;726-728.
    • (1996) Nature , vol.383 , pp. 726-728
    • Stoecklin, E.1    Wissler, M.2    Gouilleux, F.3    Groner, B.4
  • 76
    • 0030881742 scopus 로고    scopus 로고
    • Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-α) translation: Glucocorticoids inhibit TNF-α translation by blocking JNK/SAPK
    • Swantek J.L., Cobb M.H., Geppert T.D. Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) is required for lipopolysaccharide stimulation of tumor necrosis factor alpha (TNF-α) translation: glucocorticoids inhibit TNF-α translation by blocking JNK/SAPK. Molecular Cell Biology. 17:1997;6274-6282.
    • (1997) Molecular Cell Biology , vol.17 , pp. 6274-6282
    • Swantek, J.L.1    Cobb, M.H.2    Geppert, T.D.3
  • 79
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai M.-J., O'Malley B.W. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annual Review of Biochemistry. 63:1994;451-486.
    • (1994) Annual Review of Biochemistry , vol.63 , pp. 451-486
    • Tsai, M.-J.1    O'Malley, B.W.2
  • 80
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-β/SMAD signalling by the interferon-gamma/STAT pathway
    • Ulloa L., Doody J., Massaguè J. Inhibition of transforming growth factor-β/SMAD signalling by the interferon-gamma/STAT pathway. Nature. 397:1999;710-713.
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massaguè, J.3
  • 81
    • 0036352690 scopus 로고    scopus 로고
    • Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma
    • Umland S.P., Schleimer R.P., Johnston S.L. Review of the molecular and cellular mechanisms of action of glucocorticoids for use in asthma. Pulmonary Pharmacology and Therapeutics. 15:2002;35-50.
    • (2002) Pulmonary Pharmacology and Therapeutics , vol.15 , pp. 35-50
    • Umland, S.P.1    Schleimer, R.P.2    Johnston, S.L.3
  • 82
    • 0033016685 scopus 로고    scopus 로고
    • Glucocorticoid receptor down-regulates c-Jun amino terminal kinases induced by tumor necrosis factor α in fetal rat hepatocyte primary cultures
    • Ventura J.-J., Roncero C., Fabregat I., Benito M. Glucocorticoid receptor down-regulates c-Jun amino terminal kinases induced by tumor necrosis factor α in fetal rat hepatocyte primary cultures. Hepatology. 29:1999;849-857.
    • (1999) Hepatology , vol.29 , pp. 849-857
    • Ventura, J.-J.1    Roncero, C.2    Fabregat, I.3    Benito, M.4
  • 83
    • 0033485289 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid-receptor-mediated repression of gene expression
    • Webster J.C., Cidlowski J.A. Mechanisms of glucocorticoid-receptor-mediated repression of gene expression. Trends in Endocrinology and Metabolism. 10:1999;396-402.
    • (1999) Trends in Endocrinology and Metabolism , vol.10 , pp. 396-402
    • Webster, J.C.1    Cidlowski, J.A.2
  • 84
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
    • Widmann C., Gibson S., Jarpe M.B., Johnson G.L. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiological Reviews. 79:1999;143-180.
    • (1999) Physiological Reviews , vol.79 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 85
    • 0033568608 scopus 로고    scopus 로고
    • The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
    • Winzen R., Kracht M., Ritter B., Wilhelm A., Chen C.-Y.A., Shyu A.-B., Muller M., Gaestel M., Resch K., Holtmann H. The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism. EMBO Journal. 18:1999;4969-4980.
    • (1999) EMBO Journal , vol.18 , pp. 4969-4980
    • Winzen, R.1    Kracht, M.2    Ritter, B.3    Wilhelm, A.4    Chen, C.-Y.A.5    Shyu, A.-B.6    Muller, M.7    Gaestel, M.8    Resch, K.9    Holtmann, H.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.