Transforming growth factor-β1 in asthma: Measurement in bronchoalveolar lavage fluid

American Journal of Respiratory and Critical Care Medicine

Volumn 156, Issue 2 I, 1997, Pages 642-647

  Redington, Anthony E ^a,b   Madden, Jacqueline ^a   Frew, Anthony J ^a   Djukanovic, Ratko ^a   Roche, William R ^a   Holgate, Stephen T ^a   Howarth, Peter H ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BECLOMETASONE DIPROPIONATE; TRANSFORMING GROWTH FACTOR BETA1;

AIRWAY; ARTICLE; ASTHMA; ATOPY; BRONCHUS BIOPSY; BRONCHUS HYPERREACTIVITY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBEROPTIC BRONCHOSCOPY; HUMAN; HUMAN CELL; INHALATIONAL DRUG ADMINISTRATION; LUNG LAVAGE; MALE; PRIORITY JOURNAL; PROVOCATION TEST;

EID: 0030753766     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.156.2.9605065     Document Type: Article

References (22)

1. Peat, J. K., A. J. Woolcock, and K. Cullen. 1987. Rate of decline of lung function in subjects with asthma. Eur. J. Respir. Dis. 70:171-179.
2. Redington, A. E., and P. H. Howarth. 1997. Airway wall remodeling in asthma. Thorax 52:310-312.
3. Wiggs, B. R., C. Bosken, P. D. Paré, A. James, and J. C. Hogg. 1992. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am. Rev. Respir. Dis. 145:1251-1258.
4. Massagué, J. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6:597-641.
5. Teran, L. M., M. P. Carroll, A. J. Frew, A. E. Redington, D. E. Davies, I. Lindley, P. H. Howarth, M. K. Church, and S. T. Holgate. 1996. Leukocyte recruitment after local endobronchial allergen challenge in asthma: relationship to procedure and to airway interleukin-8 release. Am. J. Respir. Crit. Care Med. 154:469-476.
6. Djukanovic, R., J. W. Wilson, C. K. W. Lai, S. T. Holgate, and P. H. Howarth, 1991. The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma. Am. Rev. Respir. Dis. 143:772-777.
7. Krug, N., L. M. Teran, A. E. Redington, C. Gratziou, S. Montefort, R. Polosa, H. Brewster, P. H. Howarth, S. T. Holgate, A. J. Frew, and M. P. Carroll. 1996. Safety aspects of local endobronchial allergen challenge in asthmatic patients. Am. J. Respir. Crit. Care Med. 153:1391-1397.
8. National Heart, Lung, and Blood Institute. 1992. Workshop summary and guidelines: investigative use of bronchoscopy, lavage, and bronchial biopsies in asthma and other airway diseases. J. Allergy Clin. Immunol. 88:808-814.
9. Britten, K. M., P. H. Howarth, and W. R. Roche. 1993. Immunohistochemistry on resin sections: a comparison of resin embedding techniques for small mucosal biopsies. Biotech. Histochem. 68:271-280.
10. Yamauchi, K., Y. Martinet, P. Basset, G. A. Fells, and R. G. Crystal. 1988. High levels of transforming growth factor-β are present in the epithelial lining fluid of the normal human lower respiratory tract. Am. Rev. Respir. Dis. 137:1360-1363.
11. Perkett, E. A., R. M. Lyons, H. L. Moses, and K. L. Brigham. 1990. Transforming growth factor-β activity in sheep lung lymph during the development of pulmonary hypertension. J. Clin. Invest. 86:1459-1464.
12. Roche, W. R., R. Beasley, J. H. Williams, and S. T. Holgate. 1989. Subepithelial fibrosis in the bronchi of asthmatics. Lancet i:520-524.
13. Redington, A. E., R. Polosa, A. F. Walls, P. H. Howarth, and S. T. Holgate. 1995. Role of mast cells and basophils in asthma. Chem. Immunol. 62:22-59.
14. Pennington, D. W., A. R. Lopez, P. S. Thomas, C. Peck, and W. M. Gold. 1992. Dog mastocytoma cells produce transforming growth factor beta 1. J. Clin. Invest. 90:35-11.
15. Gordon, J. R., and S. J. Galli. 1994. Promotion of mouse fibroblast collagen gene expression by mast cells stimulated via the FcεRI: role for mast cell-derived transforming growth factor β and tumor necrosis factor α. J. Exp. Med. 180:2027-2037.
16. Baumgartner, R. A., V. A. Deramo, and M. A. Heaven. 1996. Constitutive and inducible mechanisms for synthesis and release of cytokines in immune cell lines. J. Immunol. 157:4087-4093.
17. Ohno, I., R. G. Lea, K. C. Flanders, D. A. Clark, D. Banwatt, J. Dolovich, J. Denburg, C. B. Harley, J. Gauldie, and M. Jordana. 1992. Eosinophils in chronically inflamed human upper airway tissues express transforming growth factor β1 gene (TGFβ1). J. Clin. Invest. 89:1662-1668.
18. Ohno, I., Y. Nitta, K. Yamauchi, H. Hoshi, M. Honma, K. Woolley, P. O'Byrne, G. Tamura, M. Jordana, and K. Shirato. 1996. Transforming growth factor β1 (TGFβ1) gene expression by eosinophils in asthmatic airway inflammation. Am. J. Respir. Cell Mol. Biol. 15:404-409.
19. Aubert, J.-D., B. I. Dalal, T. R. Bai, C. R. Roberts, S. Hayashi, and J. C. Hogg. 1994. Transforming growth factor β1 gene expression in human airways. Thorax 49:225-232.
20. Miyazono, K., U. Hellman, C. Wernstedt, and C.-H. Heldin. 1988. Latent high molecular weight complex of transforming growth factor β1: purification from human platelets and structural characterization. J. Biol. Chem. 263:6407-6415.
21. Dennis, P. A., and D. B. Rifkin. 1991. Cellular activation of latent transforming growth factor β requires binding to the cation-independent mannose 6-phosphate/insulin-like growth factor type II receptor. Proc. Natl. Acad. Sci. U.S.A. 88:580-584.
22. Sato, Y., and D. B. Rifkin. 1989. Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture. J. Cell Biol. 109:309-315.