In vivo resistance to corticosteroids in bronchial asthma is associated with enhanced phosphorylation of JUN N-terminal kinase and failure of prednisolone to inhibit JUN N-terminal kinase phosphorylation

Journal of Allergy and Clinical Immunology

Volumn 104, Issue 3 II, 1999, Pages 564-574

  Sousa, Ana R ^a   Lane, Stephen J ^a   Soh, Cecilia ^a   Lee, Tak H ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GUY S HOSPITAL   (United Kingdom)

Author keywords

Activating protein 1; Asthma; Corticosteroids; JUN N terminal kinase; Proto oncogene

Indexed keywords

BECLOMETASONE; CORTICOSTEROID; GLUCOCORTICOID RECEPTOR; PREDNISOLONE; PROTEIN C FOS; SALBUTAMOL; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; TUBERCULIN;

ARTICLE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; DOUBLE BLIND PROCEDURE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INHALATIONAL DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PROTO ONCOGENE; SKIN BIOPSY; T LYMPHOCYTE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTHMA; DOUBLE-BLIND METHOD; DRUG RESISTANCE; FEMALE; GLUCOCORTICOIDS; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PREDNISOLONE; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-JUN; TRANSCRIPTION FACTOR AP-1;

EID: 0032843944     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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