Chemical and biological profile of dual Cdk1 and Cdk2 inhibitors

Current Medicinal Chemistry - Anti-Cancer Agents

Volumn 3, Issue 1, 2003, Pages 1-14

  Ruetz, Stephan ^a   Fabbro, Doriano ^a   Zimmermann, Juerg ^a   Meyer, Thomas ^a   Gray, Nathanael ^b  

^a NOVARTIS PHARMA AG   (Switzerland)

^b GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINOCYCLOHEXYLAMINO) 6 (3,4 DICHLOROANILINO) 9 ETHYLPURINE; 2 (3 CHLOROANILINO) 4 [2 (3 HYDROXYPROPYLAMINO) 4 PYRIDYL]PYRIMIDINE; 2 BIS(2 HYDROXYETHYL)AMINO 9 ISOPROPYL 6 (4 METHOXYBENZYLAMINO)PURINE; 6 O CYCLOHEXYLMETHYLGUANINE; ADENOSINE TRIPHOSPHATE; CARBONYL DERIVATIVE; COMPLEMENTARY DNA; CYCLIN B; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; EPIDERMAL GROWTH FACTOR; H 717; MIMOSINE; MITOGEN ACTIVATED PROTEIN KINASE 1; OLOMOUCINE; ONCOPROTEIN; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE C ALPHA; PURINE DERIVATIVE; PURVALANOL; PURVALANOL A; PURVALANOL B; PYRIMIDINE DERIVATIVE; RETINOBLASTOMA PROTEIN; ROSCOVITINE; STAUROSPORINE; STEM CELL FACTOR; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

AFFINITY CHROMATOGRAPHY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; BINDING SITE; CANCER THERAPY; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; DRUG EFFICACY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG TOLERABILITY; GENE CONTROL; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALIGNANT TRANSFORMATION; MOLECULAR WEIGHT; NONHUMAN; ONCOGENE; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVIEW; STRUCTURE ACTIVITY RELATION; TUMOR SUPPRESSOR GENE;

EID: 0037242297     PISSN: 15680118     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568011033353605     Document Type: Review

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