-
1
-
-
0002411854
-
Cell cycle control
-
(ed.)
-
Dunphy, W.G. (ed.) (1997). Cell cycle control. Methods Enzymol., 283, 678.
-
(1997)
Methods Enzymol.
, vol.283
, pp. 678
-
-
Dunphy, W.G.1
-
2
-
-
0031466305
-
Cyclin-dependent kinases: Engines, clocks, and microprocessors
-
Morgan D. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu. Rev. Cell Dev. Biol. 13:1997;261-291.
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 261-291
-
-
Morgan, D.1
-
5
-
-
0031670668
-
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms
-
Senderowicz A., Sausville E.A.et al. Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms. J. Clin. Oncol. 16:1998;1-17.
-
(1998)
J. Clin. Oncol.
, vol.16
, pp. 1-17
-
-
Senderowicz, A.1
Sausville, E.A.2
-
7
-
-
0030271304
-
Chemical inhibitors of cyclin-dependent kinases
-
Meijer L. Chemical inhibitors of cyclin-dependent kinases. Trends Cell Biol. 6:1996;393-397.
-
(1996)
Trends Cell Biol.
, vol.6
, pp. 393-397
-
-
Meijer, L.1
-
8
-
-
0030753686
-
Chemical inhibitors of cyclin-dependent kinases
-
Meijer L., Kim S.H. Chemical inhibitors of cyclin-dependent kinases. Methods Enzymol. 283:1997;113-128.
-
(1997)
Methods Enzymol.
, vol.283
, pp. 113-128
-
-
Meijer, L.1
Kim, S.H.2
-
9
-
-
0033036758
-
Properties and potential applications of chemical inhibitors of cyclin-dependent kinases
-
Meijer L., Leclerc S., Leost M. Properties and potential applications of chemical inhibitors of cyclin-dependent kinases. Pharmacol. Ther. 82:1999;279-284.
-
(1999)
Pharmacol. Ther.
, vol.82
, pp. 279-284
-
-
Meijer, L.1
Leclerc, S.2
Leost, M.3
-
11
-
-
0025841808
-
suc1-coated microtitration plates
-
suc1-coated microtitration plates. Anticancer Res. 11:1991;1581-1590.
-
(1991)
Anticancer Res.
, vol.11
, pp. 1581-1590
-
-
Rialet, V.1
Meijer, L.2
-
12
-
-
0027186226
-
Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase
-
Kitagawa M., Okuyama A.et al. Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase. Oncogene. 8:1993;2425-2432.
-
(1993)
Oncogene
, vol.8
, pp. 2425-2432
-
-
Kitagawa, M.1
Okuyama, A.2
-
13
-
-
0028093182
-
Inhibition of cyclin-dependent kinases by purine derivatives
-
Vesely J., Meijer L.et al. Inhibition of cyclin-dependent kinases by purine derivatives. Eur. J. Biochem. 224:1994;771-786.
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 771-786
-
-
Vesely, J.1
Meijer, L.2
-
14
-
-
0028176485
-
Potent inhibition of cdc2 kinase activity by the flavonoid L86-8275
-
Losiewiecz M.D., Carlson B.A., Kaur G., Sausville E.A., Worland P.J. Potent inhibition of cdc2 kinase activity by the flavonoid L86-8275. Biochem. Biophys. Res. Commun. 201:1994;589-595.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.201
, pp. 589-595
-
-
Losiewiecz, M.D.1
Carlson, B.A.2
Kaur, G.3
Sausville, E.A.4
Worland, P.J.5
-
15
-
-
0031028163
-
Inhibition of cyclin-dependent kinases by purine analogues: Crystal structure of human cdk2 complexed with roscovitine
-
De Azevedo W.F., Leclerc S., Meijer L., Havlicek L., Strnad M., Kim S-H. Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine. Eur. J. Biochem. 243:1997;518-526.
-
(1997)
Eur. J. Biochem.
, vol.243
, pp. 518-526
-
-
De Azevedo, W.F.1
Leclerc, S.2
Meijer, L.3
Havlicek, L.4
Strnad, M.5
Kim, S.-H.6
-
16
-
-
0031037714
-
Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 & cdk5
-
Meijer L., Moulinoux J.P.et al. Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 & cdk5. Eur. J. Biochem. 243:1997;527-536.
-
(1997)
Eur. J. Biochem.
, vol.243
, pp. 527-536
-
-
Meijer, L.1
Moulinoux, J.P.2
-
17
-
-
0032563315
-
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors
-
Gray N.S., Schultz P.G.et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science. 281:1998;533-538.
-
(1998)
Science
, vol.281
, pp. 533-538
-
-
Gray, N.S.1
Schultz, P.G.2
-
18
-
-
0033128165
-
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
-
Hoessel R., Meijer L.et al. Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases. Nat. Cell Biol. 1:1999;60-67.
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 60-67
-
-
Hoessel, R.1
Meijer, L.2
-
19
-
-
0033614949
-
The Paullones, a series of cyclin-dependent kinase inhibitors: Synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity
-
Schultz C., Kunick C.et al. The Paullones, a series of cyclin-dependent kinase inhibitors: synthesis, evaluation of CDK1/cyclin B inhibition, and in vitro antitumor activity. J. Med. Chem. 42:1999;2909-2919.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 2909-2919
-
-
Schultz, C.1
Kunick, C.2
-
20
-
-
0033152122
-
Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases
-
Zaharevitz D., Sausville E.A.et al. Discovery and initial characterization of the paullones, a novel class of small-molecule inhibitors of cyclin-dependent kinases. Cancer Res. 59:1999;2566-2569.
-
(1999)
Cancer Res.
, vol.59
, pp. 2566-2569
-
-
Zaharevitz, D.1
Sausville, E.A.2
-
21
-
-
0034010742
-
Inhibition of cyclin-dependent kinases 1, 2 & 5, GSK-3β and casein kinase 1 by hymenialdisine, a marine sponge constituent
-
Meijer L., Pettit G.R.et al. Inhibition of cyclin-dependent kinases 1, 2 & 5, GSK-3β and casein kinase 1 by hymenialdisine, a marine sponge constituent. Chem. Biol. 7:2000;51-63.
-
(2000)
Chem. Biol.
, vol.7
, pp. 51-63
-
-
Meijer, L.1
Pettit, G.R.2
-
22
-
-
15444355744
-
CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation
-
Brooks E.E., Shiffman D.et al. CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation. J. Biol. Chem. 272:1997;29207-29211.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29207-29211
-
-
Brooks, E.E.1
Shiffman, D.2
-
23
-
-
0030877852
-
Prevention of graft coronary arteriosclerosis by antisense cdk2 kinase oligonucleotide
-
Suzuki J.I., Sekiguchi M.et al. Prevention of graft coronary arteriosclerosis by antisense cdk2 kinase oligonucleotide. Nature Med. 3:1997;900-903.
-
(1997)
Nature Med.
, vol.3
, pp. 900-903
-
-
Suzuki, J.I.1
Sekiguchi, M.2
-
24
-
-
0030781307
-
Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with roscovitine, a novel CDK2 antagonist
-
Pippin J.W., Qu Q., Meijer L., Shankland S.J. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with roscovitine, a novel CDK2 antagonist. J. Clin. Invest. 100:1997;2512-2520.
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2512-2520
-
-
Pippin, J.W.1
Qu, Q.2
Meijer, L.3
Shankland, S.J.4
-
25
-
-
0030751147
-
Cell-cycle control and renal disease
-
Shankland S.J. Cell-cycle control and renal disease. Kidney Int. 52:1997;294-308.
-
(1997)
Kidney Int.
, vol.52
, pp. 294-308
-
-
Shankland, S.J.1
-
26
-
-
0031009357
-
Inhibition of cellular cdk2 activity blocks human cytomegalovirus replication
-
Bresnahan W.A., Boldogh I., Chi P., Thompson E.A., Albrecht T. Inhibition of cellular cdk2 activity blocks human cytomegalovirus replication. Virology. 231:1997;239-247.
-
(1997)
Virology
, vol.231
, pp. 239-247
-
-
Bresnahan, W.A.1
Boldogh, I.2
Chi, P.3
Thompson, E.A.4
Albrecht, T.5
-
27
-
-
14444281157
-
P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro
-
Mancebo H.S.Y., Flores O.et al. P-TEFb kinase is required for HIV Tat transcriptional activation in vivo and in vitro. Genes Dev. 11:1997;2633-2644.
-
(1997)
Genes Dev.
, vol.11
, pp. 2633-2644
-
-
Mancebo, H.S.Y.1
Flores, O.2
-
28
-
-
0031746015
-
Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription
-
Schang L.M., Phillips J., Schaffer P.A. Requirement for cellular cyclin-dependent kinases in herpes simplex virus replication and transcription. J. Virol. 72:1998;5626-5637.
-
(1998)
J. Virol.
, vol.72
, pp. 5626-5637
-
-
Schang, L.M.1
Phillips, J.2
Schaffer, P.A.3
-
29
-
-
0032901995
-
Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase
-
Ye M., Duus K.M., Peng J., Price D.H., Grose C. Varicella-zoster virus Fc receptor component gI is phosphorylated on its endodomain by a cyclin-dependent kinase. J. Virol. 73:1999;1320-1330.
-
(1999)
J. Virol.
, vol.73
, pp. 1320-1330
-
-
Ye, M.1
Duus, K.M.2
Peng, J.3
Price, D.H.4
Grose, C.5
-
30
-
-
0031045216
-
Physiology and pathology of tau protein kinases in relation to Alzheimer's disease
-
Imahori K., Uchida T. Physiology and pathology of tau protein kinases in relation to Alzheimer's disease. J. Biochem. 121:1997;179-188.
-
(1997)
J. Biochem.
, vol.121
, pp. 179-188
-
-
Imahori, K.1
Uchida, T.2
-
32
-
-
0023867410
-
1 kinase during the sea urchin egg mitotic divisions
-
1 kinase during the sea urchin egg mitotic divisions. Exp. Cell Res. 174:1988;116-129.
-
(1988)
Exp. Cell Res.
, vol.174
, pp. 116-129
-
-
Meijer, L.1
Pondaven, P.2
-
33
-
-
0023945117
-
6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity
-
Néant I., Guerrier P. 6-Dimethylaminopurine blocks starfish oocyte maturation by inhibiting a relevant protein kinase activity. Exp. Cell Res. 176:1988;68-79.
-
(1988)
Exp. Cell Res.
, vol.176
, pp. 68-79
-
-
Néant, I.1
Guerrier, P.2
-
34
-
-
0032492705
-
Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases
-
Legraverend M., Ludwig O., Bisagni E., Leclerc S., Meijer L. Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases. Bioorg. Med. Chem. Lett. 8:1998;793-798.
-
(1998)
Bioorg. Med. Chem. Lett.
, vol.8
, pp. 793-798
-
-
Legraverend, M.1
Ludwig, O.2
Bisagni, E.3
Leclerc, S.4
Meijer, L.5
-
36
-
-
0031575637
-
Combinatorial synthesis of 2,9-substituted purines
-
Gray N.S., Schultz P.G. Combinatorial synthesis of 2,9-substituted purines. Tetrahedron Lett. 38:1997;1161-1164.
-
(1997)
Tetrahedron Lett.
, vol.38
, pp. 1161-1164
-
-
Gray, N.S.1
Schultz, P.G.2
-
37
-
-
0031013919
-
Facile preparation of 2,6-disubstituted purines using solid phase chemistry
-
Nugiel D.A., Cornelius L.A.M., Corbett J.W. Facile preparation of 2,6-disubstituted purines using solid phase chemistry. J. Org. Chem. 62:1997;201-203.
-
(1997)
J. Org. Chem.
, vol.62
, pp. 201-203
-
-
Nugiel, D.A.1
Cornelius, L.A.M.2
Corbett, J.W.3
-
38
-
-
0033150476
-
Synthesis and application of 2,6,9-trisubstituted purine library towards the development of functionally diverse CDK inhibitors
-
Chang Y.T., Schultz P.G.et al. Synthesis and application of 2,6,9-trisubstituted purine library towards the development of functionally diverse CDK inhibitors. Chem. Biol. 6:1999;361-375.
-
(1999)
Chem. Biol.
, vol.6
, pp. 361-375
-
-
Chang, Y.T.1
Schultz, P.G.2
-
39
-
-
0037792445
-
Starfish oocyte maturation: From prophase to metaphase
-
Meijer L., Mordret G. Starfish oocyte maturation: from prophase to metaphase. Semin. Dev. Biol. 5:1994;165-171.
-
(1994)
Semin. Dev. Biol.
, vol.5
, pp. 165-171
-
-
Meijer, L.1
Mordret, G.2
-
40
-
-
0029981099
-
cdc2 on its Thr-14 and Tyr-15 residues at the prophase/metaphase transition
-
cdc2 on its Thr-14 and Tyr-15 residues at the prophase/metaphase transition. J. Biol. Chem. 271:1996;27847-27854.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27847-27854
-
-
Borgne, A.1
Meijer, L.2
-
41
-
-
0005221605
-
Contrôle neurohormonal de la maturation des ovocytes chez Arenicola marina (Annélide Polychète)
-
Etude in vitro [Neurohormonal control of oocyte maturation in Arericola marina: in vivo study]
-
Meijer L., Durchon M. Contrôle neurohormonal de la maturation des ovocytes chez Arenicola marina (Annélide Polychète). C.R. Acad. Sci. Paris. 285:1977;377-380. Etude in vitro [Neurohormonal control of oocyte maturation in Arericola marina: in vivo study].
-
(1977)
C.R. Acad. Sci. Paris
, vol.285
, pp. 377-380
-
-
Meijer, L.1
Durchon, M.2
-
43
-
-
0033609044
-
A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: Biochemical identification using Xenopus egg extracts
-
Rosania G.R., Merlie J., Gray N., Chang Y-T., Schultz P.G., Heald R. A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts. Proc. Natl. Acad. Sci. USA. 96:1999;4797-4802.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4797-4802
-
-
Rosania, G.R.1
Merlie, J.2
Gray, N.3
Chang, Y.-T.4
Schultz, P.G.5
Heald, R.6
-
44
-
-
0030705190
-
Identification, cloning, and mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum
-
Barik S., Taylor R.E., Chakrabarti D. Identification, cloning, and mutational analysis of the casein kinase 1 cDNA of the malaria parasite, Plasmodium falciparum. J. Biol. Chem. 272:1997;26132-26138.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26132-26138
-
-
Barik, S.1
Taylor, R.E.2
Chakrabarti, D.3
-
45
-
-
0029020282
-
The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
-
Hanks S.K., Hunter T. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9:1995;576-596.
-
(1995)
FASEB J.
, vol.9
, pp. 576-596
-
-
Hanks, S.K.1
Hunter, T.2
-
46
-
-
0029090514
-
Multiple modes of ligand recognition: Crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine
-
Schulze-Gahmen U., Kim S.-H.et al. Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine. Proteins. 22:1995;378-391.
-
(1995)
Proteins
, vol.22
, pp. 378-391
-
-
Schulze-Gahmen, U.1
Kim, S.-H.2
-
47
-
-
0029850471
-
High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: Bound waters and natural ligand as guides for inhibitor design
-
Schulze-Gahmen U., De Bondt H.L., Kim S.-H. High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design. J. Med. Chem. 39:1996;4540-4546.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4540-4546
-
-
Schulze-Gahmen, U.1
De Bondt, H.L.2
Kim, S.-H.3
-
48
-
-
0032530336
-
Structural basis of inhibitor selectivity in MAP kinases
-
Wang Z., Goldsmith E.J.et al. Structural basis of inhibitor selectivity in MAP kinases. Structure. 6:1998;1117-1128.
-
(1998)
Structure
, vol.6
, pp. 1117-1128
-
-
Wang, Z.1
Goldsmith, E.J.2
-
49
-
-
0033631382
-
The cell cycle in protozoan parasites
-
L. Meijer, A. Jezequel, & B. Ducommun. New York: Plenum Press
-
Doerig C., Chakrabarti D., Kappes B., Matthews K. The cell cycle in protozoan parasites. Meijer L., Jezequel A., Ducommun B. Progress in Cell Cycle Research, vol. 4. 2000;163-183 Plenum Press, New York.
-
(2000)
Progress in Cell Cycle Research, Vol. 4
, pp. 163-183
-
-
Doerig, C.1
Chakrabarti, D.2
Kappes, B.3
Matthews, K.4
|