Crystal structure of human cyclin-dependent kinase 2 in complex with the adenine-derived inhibitor H717

Journal of Medicinal Chemistry

Volumn 44, Issue 4, 2001, Pages 524-530

  Dreyer, M K ^a,d   Borcherding, D R ^b   Dumont, J A ^b,c   Peet, N P ^b   Tsay, J T ^b   Wright, P S ^b   Bitonti, A J ^b,c   Shen, J ^b   Kim, S H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SANOFI   (France)

^c Syntonix Pharmaceuticals Inc   (United States)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE DERIVATIVE; ADENOSINE TRIPHOSPHATE; CYCLIN DEPENDENT KINASE 2; PURINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANCER THERAPY; CELL CYCLE; CELL GROWTH; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; EUKARYOTE; GENETIC TRANSCRIPTION; SYNTHESIS; TRANSLATION INITIATION;

EID: 0035865934     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm001043t     Document Type: Article

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