Phenylamino-pyrimidine (PAP) derivatives: A new class of potent and selective inhibitors of protein kinase C (PKC)

Archiv der Pharmazie

Volumn 329, Issue 7, 1996, Pages 371-376

  Zimmermann, Jürg ^a   Caravatti, Giorgio ^a   Mett, Helmut ^a   Meyer, Thomas ^a   Müller, Marcel ^a   Lydon, Nicholas B ^a   Fabbro, Doriano ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

anti proliferative effect; phenylamino pyrimidine; protein kinase C; signal transduction

Indexed keywords

N (3 NITROPHENYL) 4 (3 PYRIDYL) 2 PYRIMIDINAMINE; N [3 (1 IMIDAZOYL)PHENYL] 4 (3 PYRIDYL) 2 PYRIMIDINAMINE; PROTEIN KINASE C INHIBITOR; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; DRUG ACTIVITY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

ANILINE COMPOUNDS; CELL DIVISION; ENZYME INHIBITORS; HUMANS; ISOENZYMES; PROTEIN KINASE C; PYRIMIDINES; SUBSTRATE SPECIFICITY; TUMOR CELLS, CULTURED;

EID: 0030057160     PISSN: 03656233     EISSN: None     Source Type: Journal    
DOI: 10.1002/ardp.19963290707     Document Type: Article

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