The Bmi-1 oncogene induces telomerase activity and immortalizes human mammary epithelial cells

Cancer Research

Volumn 62, Issue 16, 2002, Pages 4736-4745

  Dimri, Goberdhan P ^a   Martinez, Jose Luis ^a   Jacobs, Jacqueline J L ^c   Keblusek, Petra ^c   Itahana, Koji ^d   Van Lohuizen, Maarten ^c   Campisi, Judith ^d   Wazer, David E ^a   Band, Vimla ^a,b  

^a TUFTS MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NETHERLANDS CANCER INSTITUTE   (Netherlands)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; MYC PROTEIN; ONCOPROTEIN; ONCOPROTEIN BMI 1; RNA DIRECTED DNA POLYMERASE; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; BREAST EPITHELIUM; CELL AGING; CELL DIVISION; CELL IMMORTALIZATION; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INDUCTION; GENE; GENE DELETION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HTERT GENE; HUMAN; HUMAN CELL; ONCOGENE; ONCOGENE BMI 1; ONCOGENE C MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION;

BINDING SITES; BREAST; BREAST NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; DNA-BINDING PROTEINS; DOWN-REGULATION; ENZYME INDUCTION; EPITHELIAL CELLS; HUMANS; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-MYC; REPRESSOR PROTEINS; TELOMERASE; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 0037102196     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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