-
9
-
-
0032567967
-
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
-
(1998)
Curr Biol
, vol.8
, pp. 279-282
-
-
Vaziri, H.1
Benchimol, S.2
-
10
-
-
0034616215
-
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase
-
(2000)
J Biol Chem
, vol.275
, pp. 10072-10076
-
-
Ouellette, M.M.1
Liao, M.2
Herbert, B.S.3
Johnson, M.4
Holt, S.E.5
Liss, H.S.6
Shay, J.W.7
Wright, W.E.8
-
11
-
-
0010045614
-
Extension of life-span by introduction of telomerase into normal human cells
-
(1998)
Science
, vol.279
, pp. 349-352
-
-
Bodnar, A.G.1
Ouellette, M.2
Frolkis, M.3
Holt, S.E.4
Chui, C.-P.5
Morin, G.B.6
Harley, C.B.7
Shay, J.W.8
Lichtsteiner, S.9
Wright, W.E.10
-
12
-
-
0032923742
-
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
-
(1999)
Nat Genet
, vol.21
, pp. 111-114
-
-
Jiang, X.R.1
Jimenez, G.2
Chang, E.3
Frolkis, M.4
Kusler, B.5
Sage, M.6
Beeche, M.7
Bodnar, A.G.8
Wahl, G.M.9
Tlsty, T.D.10
Chiu, C.P.11
-
13
-
-
0032924343
-
Absence of cancer-associated changes in human fibroblasts immortalized with telomerase
-
(1999)
Nat Genet
, vol.21
, pp. 115-118
-
-
Morales, C.P.1
Holt, S.E.2
Ouellette, M.3
Kaur, K.J.4
Yan, Y.5
Wilson, K.S.6
White, M.A.7
Wright, W.E.8
Shay, J.W.9
-
17
-
-
0033543760
-
Human endothelial cell life extension by telomerase expression
-
(1999)
J Biol Chem
, vol.274
, pp. 26141-26148
-
-
Yang, J.1
Chang, E.2
Cherry, A.M.3
Bangs, C.D.4
Oei, Y.5
Bodnar, A.6
Bronstein, A.7
Chiu, C.P.8
Herron, G.S.9
-
18
-
-
0033987424
-
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts
-
(2000)
Nat Genet
, vol.24
, pp. 16-17
-
-
Wyllie, F.S.1
Jones, C.J.2
Skinner, J.W.3
Haughton, M.F.4
Wallis, C.5
Wynford-Thomas, D.6
Faragher, R.G.7
Kipling, D.8
-
21
-
-
0033979731
-
Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1436-1447
-
-
Dickson, M.A.1
Hahn, W.C.2
Ino, Y.3
Ronfard, V.4
Wu, J.Y.5
Weinberg, R.A.6
Louis, D.N.7
Li, F.P.8
Rheinwald, J.G.9
-
22
-
-
0033842950
-
Genetic and epigenetic changes in human epithelial cells immortalized by telomerase
-
(2000)
Am J Pathol
, vol.156
, pp. 1537-1547
-
-
Farwell, D.G.1
Shera, K.A.2
Koop, J.I.3
Bonnet, G.A.4
Matthews, C.P.5
Reuther, G.W.6
Coltrera, M.D.7
McDougall, J.K.8
Klingelhutz, A.J.9
-
23
-
-
0033941559
-
Evidence for a telomere-independent 'clock' limiting RAS oncogene-driven proliferation of human thyroid epithelial cells
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5690-5699
-
-
Jones, C.J.1
Kipling, D.2
Morris, M.3
Hepburn, P.4
Skinner, J.5
Bounacer, A.6
Wyllie, F.S.7
Ivan, M.8
Bartek, J.9
Wynford-Thomas, D.10
Bond, J.A.11
-
24
-
-
0033564106
-
p16/pRb pathway alterations are required for bypassing senescence in human prostate epithelial cells
-
(1999)
Cancer Res
, vol.59
, pp. 2957-2964
-
-
Jarrard, D.F.1
Sarkar, S.2
Shi, Y.3
Yeager, T.R.4
Magrane, G.5
Kinoshita, H.6
Nassif, N.7
Meisner, L.8
Newton, M.A.9
Waldman, F.M.10
Reznikoff, C.A.11
-
28
-
-
0034284973
-
Extension of life-span with superoxide dismutase/catalase mimetics
-
(2000)
Science
, vol.289
, pp. 1567-1569
-
-
Melov, S.1
Ravenscroft, J.2
Malik, S.3
Gill, M.S.4
Walker, D.W.5
Clayton, P.E.6
Wallace, D.C.7
Malfroy, B.8
Doctrow, S.R.9
Lithgow, G.J.10
-
29
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
36
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
Wynshaw-Boris, A.11
-
37
-
-
0030659153
-
Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation
-
(1997)
Nat Genet
, vol.17
, pp. 423-430
-
-
Connor, F.1
Bertwistle, D.2
Mee, P.J.3
Ross, G.M.4
Swift, S.5
Grigorieva, E.6
Tybulewicz, V.L.7
Ashworth, A.8
-
38
-
-
0032980573
-
Postnatal growth failure, short life span, and early onset of cellular senescence and subsequent immortalization in mice lacking the xeroderma pigmentosum group G gene
-
(1999)
Mol Cell Biol
, vol.19
, pp. 2366-2372
-
-
Harada, Y.N.1
Shiomi, N.2
Koike, M.3
Ikawa, M.4
Okabe, M.5
Hirota, S.6
Kitamura, Y.7
Kitagawa, M.8
Matsunaga, T.9
Nikaido, O.10
Shiomi, T.11
-
39
-
-
0033993450
-
The p53 tumor suppressor protein does not regulate expression of its own inhibitor, MDM2, except under conditions of stress
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2023-2030
-
-
Mendrysa, S.M.1
Perry, M.E.2
-
41
-
-
0033834247
-
Telomere dynamics in cancer progression and prevention: Fundamental differences in human and mouse telomere biology
-
(2000)
Nat Med
, vol.6
, pp. 849-851
-
-
Wright, W.E.1
Shay, J.W.2
-
45
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
(1999)
J Biol Chem
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
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