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Volumn 2, Issue 3, 2000, Pages 148-155

p16(INK4A) and p19(ARF) act in overlapping pathways in cellular immortalization

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; GENE PRODUCT; PROTEIN P16; PROTEIN P19; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; CRE RECOMBINASE; INTEGRASE; MDM2 PROTEIN, MOUSE; NUCLEAR PROTEIN; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; PROTEIN; PROTEIN MDM2; PROTEIN P14ARF; PROTEIN P16INK4A; VIRUS PROTEIN; VIRUS T ANTIGEN;

EID: 0033622003     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35004020     Document Type: Article
Times cited : (258)

References (33)
  • 3
    • 0010045614 scopus 로고    scopus 로고
    • Extension of life-span by introduction of telomerase into normal human cells
    • (1998) Science , vol.279 , pp. 349-352
    • Bodnar, A.G.1
  • 5
    • 0030931491 scopus 로고    scopus 로고
    • Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
    • (1997) Cell , vol.91 , pp. 25-34
    • Blasco, M.A.1
  • 8
  • 9
    • 0030728468 scopus 로고    scopus 로고
    • Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19(ARF)
    • (1997) Cell , vol.91 , pp. 649-659
    • Kamijo, T.1
  • 10
    • 0029993450 scopus 로고    scopus 로고
    • Role of the INK4a locus in tumor suppression and cell mortality
    • (1996) Cell , vol.85 , pp. 27-37
    • Serrano, M.1
  • 11
    • 0030477686 scopus 로고    scopus 로고
    • Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts
    • (1996) Proc. Natl Acad. Sol. USA , vol.93 , pp. 13742-13747
    • Alcorta, D.A.1
  • 13
    • 0032487675 scopus 로고    scopus 로고
    • Both Rb/p16(INK4A) inactivation and telomerase activity are required to immortalize human epithelial cells
    • (1998) Nature , vol.396 , pp. 84-88
    • Kiyono, T.1
  • 14
    • 0029807327 scopus 로고    scopus 로고
    • Association of extended in vitro proliferative potential with loss of p16INK4 expression
    • (1996) Oneogene , vol.13 , pp. 1259-1268
    • Noble, J.R.1
  • 18
    • 0029054399 scopus 로고
    • Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16
    • (1995) Nature , vol.375 , pp. 503-506
    • Lukas, J.1
  • 20
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 21
    • 0032549704 scopus 로고    scopus 로고
    • The Ink 4a tumor suppressor gene product, p19(ARF), interacts with MDM2 and neutralizes MDM2's inhibition of p53
    • (1998) Cell , vol.92 , pp. 713-723
    • Pomerantz, J.1
  • 23
    • 0029028354 scopus 로고
    • Interaction between the retinoblastoma protein and the oncoprotein MDM2
    • (1995) Nature , vol.375 , pp. 694-698
    • Xiao, Z.X.1
  • 29
    • 0032160407 scopus 로고    scopus 로고
    • Key roles for E2FI in signaling p53-dependent apoptosis and in cell division within developing tumors
    • (1998) Mol. Cell , vol.2 , pp. 283-292
    • Pan, H.1
  • 31
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 33
    • 0030714115 scopus 로고    scopus 로고
    • Methylation of the multi tumor suppressor gene-2 (MTS2,CDKNI, p15(INK4B)) in childhood acute lymphoblasticleukemia
    • (1997) Oncogene , vol.15 , pp. 2609-2614
    • Iravani, M.1    Dhat, R.2    Price, C.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.