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Biochemistry

Volumn 39, Issue 40, 2000, Pages 12450-12456

Proteolytic activation of recombinant pro-memapsin 2 (pro-β-secretase) studied with new fluorogenic substrates

(4) Ermolieff, J a Loy, J A a,b Koelsch, G a Tang, J a,b

a OKLAHOMA MEDICAL RESEARCH FOUNDATION (United States)

b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ASPARTIC PROTEINASE; BETA SECRETASE; CLOSTRIPAIN; ENZYME PRECURSOR; FLUORESCENT DYE; KALLIKREIN; PROMEMAPSIN 2; PROTEIN PRECURSOR; TRYPSIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; DISSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; FLUORESCENCE; MICHAELIS CONSTANT; PH; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMYLOID PRECURSOR PROTEIN SECRETASES; ASPARTIC ENDOPEPTIDASES; BINDING, COMPETITIVE; CHROMOGENIC COMPOUNDS; ENDOPEPTIDASES; ENZYME ACTIVATION; ENZYME PRECURSORS; FLUORESCENT DYES; GLYCINE; HUMANS; HYDROLYSIS; KINETICS; LEUCINE; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTEASE INHIBITORS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; SURFACE PLASMON RESONANCE;

EID: 0034633995 PISSN: 00062960 EISSN: None Source Type: Journal
DOI: 10.1021/bi001494f Document Type: Article

Times cited : (136)

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